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公开(公告)号：US20180021508A1
公开(公告)日：2018-01-25
申请号：US15548981
申请日：2016-02-10
CPC分类号： A61M5/14248 , A61M5/158 , A61M5/3287 , A61M2005/14252 , A61M2005/1583 , A61M2005/1585 , A61M2205/13 , A61M2205/18 , A61M2205/44 , A61M2205/581 , A61M2205/583 , A61M2207/00
摘要： An insertion mechanism (200) for a drug pump (10, 1300) includes an insertion mechanism (200) housing (202, 1202, 2202, 3202); a sleeve (220, 1220, 2220, 3220); a rotational biasing member (210, 1210, 2210, 3210) initially held in an energized state; a retraction biasing member (216, 1216, 2216, 3216) and a hub (212, 1212, 2212, 3212) connected to a proximal end of a needle (214, 1214, 2214, 3214), wherein the retraction biasing member (216, 1216, 2216, 3216) is held initially in an energized state between the hub (212, 1212, 2212, 3212) and the sleeve (220, 1220, 2220, 3220). The needle (214, 1214, 2214, 3214) is inserted into a target tissue by the rotational biasing member (210, 1210, 2210, 3210) and interaction between the hub (212, 1212, 2212, 3212) and housing (202, 1202, 2202, 3202). Retraction of the needle (214, 1214, 2214, 3214) is caused by decompressing or de-energizing of the retraction biasing member (216, 1216, 2216, 3216). A drug delivery pump includes an activation mechanism (14), a drive mechanism (100), a sterile access connection (300), and the insertion mechanism (200). Assembly and operation methods are provided.
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公开(公告)号：US20170281859A1
公开(公告)日：2017-10-05
申请号：US15625563
申请日：2017-06-16
发明人： Ryan M. Agard , Ian B. Hanson , Nicholas J. Ciccarelli , Sean M. O'Connor , Kevin Bokelman , Paul F. Bente, IV , John C. Love , Christopher Edward Hatch
CPC分类号： A61M5/14216 , A61M5/14248 , A61M5/1454 , A61M5/14566 , A61M5/172 , A61M2005/14252 , A61M2005/2474 , A61M2205/3317 , A61M2205/3379 , A61M2205/50 , A61M2205/58 , A61M2205/82
摘要： A drive mechanism includes a housing, a piston adapted to impart movement to a plunger seal within a drug container, a plurality of biasing members disposed in parallel, and a retainer. The biasing members are disposed to release energy to cause movement of the piston from a retracted first position to the extended second position, the piston bearing against the plunger seal to dispense medicine. The retainer is disposed to maintain the biasing members in the energized position and to release the biasing members to permit the piston to dispense the medicine. The drive mechanism may also include an end-of-dose indicator to identify at least one of when the sleeve assembly is disposed subjacent a window in the housing the relative motion of the sleeve assembly with reference to the window or another reference component, the stoppage of such motion, and the rated or change of rate of motion.
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公开(公告)号：US09707335B2
公开(公告)日：2017-07-18
申请号：US14230784
申请日：2014-03-31
发明人： Ryan M. Agard , Ian B. Hanson , Nicholas J. Ciccarelli , Sean M. O'Connor , Kevin Bokelman , Paul F. Bente, IV , John C. Love , Christopher Edward Hatch
CPC分类号： A61M5/14216 , A61M5/14248 , A61M5/1454 , A61M5/14566 , A61M5/172 , A61M2005/14252 , A61M2005/2474 , A61M2205/3317 , A61M2205/3379 , A61M2205/50 , A61M2205/58 , A61M2205/82
摘要： A drive mechanism includes a housing, a piston adapted to impart movement to a plunger seal within a drug container, a plurality of biasing members disposed in parallel, and a retainer. The biasing members are disposed to release energy to cause movement of the piston from a retracted first position to the extended second position, the piston bearing against the plunger seal to dispense medicine. The retainer is disposed to maintain the biasing members in the energized position and to release the biasing members to permit the piston to dispense the medicine. The drive mechanism may also include an end-of-dose indicator to identify at least one of when the sleeve assembly is disposed subjacent a window in the housing, the relative motion of the sleeve assembly with reference to the window or another reference component, the stoppage of such motion, and the rated or change of rate of motion.
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公开(公告)号：US20140296787A1
公开(公告)日：2014-10-02
申请号：US14230784
申请日：2014-03-31
发明人： Ryan M. Agard , Ian B. Hanson , Nicholas J. Ciccarelli , Sean M. O'Connor , Kevin Bokelman , Paul F. Bente, IV , John C. Love , Christopher Edward Hatch
IPC分类号： A61M5/142
CPC分类号： A61M5/14216 , A61M5/14248 , A61M5/1454 , A61M5/14566 , A61M5/172 , A61M2005/14252 , A61M2005/2474 , A61M2205/3317 , A61M2205/3379 , A61M2205/50 , A61M2205/58 , A61M2205/82
摘要： A drive mechanism includes a housing, a piston adapted to impart movement to a plunger seal within a drug container, a plurality of biasing members disposed in parallel, and a retainer. The biasing members are disposed to release energy to cause movement of the piston from a retracted first position to the extended second position, the piston bearing against the plunger seal to dispense medicine. The retainer is disposed to maintain the biasing members in the energized position and to release the biasing members to permit the piston to dispense the medicine. The drive mechanism may also include an end-of-dose indicator to identify at least one of when the sleeve assembly is disposed subjacent a window in the housing, the relative motion of the sleeve assembly with reference to the window or another reference component, the stoppage of such motion, and the rated or change of rate of motion.
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公开(公告)号：US20180008769A1
公开(公告)日：2018-01-11
申请号：US15651807
申请日：2017-07-17
发明人： Sean M. O'Connor , Ian B. Hanson , Paul F. Bente, IV , Rajan Ramaswamy , Daniel S. Codd , Scott W. Beaver , Kevin L. Bokelman , John C. Love
CPC分类号： A61M5/14248 , A61M5/1452 , A61M5/162 , A61M5/16813 , A61M5/16877 , A61M2005/1581
摘要： A user-initiated fluid pathway connection includes: a connection hub, a piercing member, a sterile sleeve, and a drug container having a cap, a pierceable seal, a barrel, and a plunger seal, wherein the piercing member is initially retained within the sterile sleeve between the connection hub and the pierceable seal of the drug container. The connection hub may include an internal aperture within the connection hub which functions as a flow restrictor and wherein a piercing member is connected to one end of the internal aperture and a fluid conduit is connected to another end of the internal aperture. A drug delivery pump with integrated sterility maintenance features includes a housing, upon which an activation mechanism, an insertion mechanism, a fluid pathway connection as described above, a power and control system, and a drive mechanism connected to a drug container are mounted. Methods of assembly and operation are also provided.
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