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公开(公告)号:US07598423B2
公开(公告)日:2009-10-06
申请号:US11718753
申请日:2005-11-15
申请人: Thomas Daniel Aicher , Guillermo S. Cortez , Todd Michael Groendyke , Albert Khilevich , James Allen Knobelsdorf , Fredrik Pehr Marmsater , Jeffrey Michael Schkeryantz , Tony Pisal Tang , Nicholas Andrew Magnus
发明人: Thomas Daniel Aicher , Guillermo S. Cortez , Todd Michael Groendyke , Albert Khilevich , James Allen Knobelsdorf , Fredrik Pehr Marmsater , Jeffrey Michael Schkeryantz , Tony Pisal Tang , Nicholas Andrew Magnus
IPC分类号: C07D239/26 , C07D239/28 , C07D241/10 , C07D401/10 , C07D213/02 , C07D291/04 , C07D271/06 , C07D277/20 , C07D417/10 , C07D333/06 , C07D319/06 , C07C49/76
CPC分类号: C07C229/60 , C07C317/44 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/79 , C07D213/80 , C07D213/84 , C07D213/85 , C07D257/04 , C07D401/04 , C07D401/12
摘要: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
摘要翻译: 本申请涉及式I的取代羟基苯基酮化合物或其药学上可接受的盐,其药物组合物及其在治疗偏头痛中的用途。 本申请还涉及制备式I化合物的方法和其中有用的中间体化合物。
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公开(公告)号:US20090318481A1
公开(公告)日:2009-12-24
申请号:US12549552
申请日:2009-08-28
申请人: Thomas Daniel AICHER , Guillermo S. CORTEZ , Todd Michael GROENDYKE , Albert KHILEVICH , James Allen KNOBELSDORF , Fredrik Pehr MARMSATER , Jeffrey Michael SCHKERYANTZ , Tony Pisal TANG
发明人: Thomas Daniel AICHER , Guillermo S. CORTEZ , Todd Michael GROENDYKE , Albert KHILEVICH , James Allen KNOBELSDORF , Fredrik Pehr MARMSATER , Jeffrey Michael SCHKERYANTZ , Tony Pisal TANG
IPC分类号: A61K31/19 , C07D309/00 , A61K31/695 , A61K31/35 , C07C255/00 , A61K31/24 , C07D401/00 , C07D211/78 , C07D239/02 , C07D333/24 , A61K31/381 , A61K31/425 , C07D277/00 , A61K31/505 , C07D271/06 , A61K31/44 , C07C229/00 , A61K31/275 , C07D257/04 , A61K31/41 , C07C63/04
CPC分类号: C07C229/60 , C07C317/44 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/79 , C07D213/80 , C07D213/84 , C07D213/85 , C07D257/04 , C07D401/04 , C07D401/12
摘要: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
摘要翻译: 本申请涉及式I的取代羟基苯基酮化合物或其药学上可接受的盐,其药物组合物及其在治疗偏头痛中的用途。 本申请还涉及制备式I化合物的方法和其中有用的中间体化合物。
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公开(公告)号:US07816523B2
公开(公告)日:2010-10-19
申请号:US12549552
申请日:2009-08-28
申请人: Thomas Daniel Aicher , Guillermo S. Cortez , Todd Michael Groendyke , Albert Khilevich , James Allen Knobelsdorf , Fredrik Pehr Marmsater , Jeffrey Michael Schkeryantz , Tony Pisal Tang
发明人: Thomas Daniel Aicher , Guillermo S. Cortez , Todd Michael Groendyke , Albert Khilevich , James Allen Knobelsdorf , Fredrik Pehr Marmsater , Jeffrey Michael Schkeryantz , Tony Pisal Tang
IPC分类号: C07D239/32 , C07D213/02
CPC分类号: C07C229/60 , C07C317/44 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/79 , C07D213/80 , C07D213/84 , C07D213/85 , C07D257/04 , C07D401/04 , C07D401/12
摘要: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
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公开(公告)号:US07678794B2
公开(公告)日:2010-03-16
申请号:US11718742
申请日:2005-11-15
申请人: Thomas Daniel Aicher , Guillermo S. Cortez , Todd Michael Groendyke , Albert Khilevich , James Allen Knobelsdorf , Fredrik Pehr Marmsater , Jeffrey Michael Schkeryantz , Tony Pisal Tang
发明人: Thomas Daniel Aicher , Guillermo S. Cortez , Todd Michael Groendyke , Albert Khilevich , James Allen Knobelsdorf , Fredrik Pehr Marmsater , Jeffrey Michael Schkeryantz , Tony Pisal Tang
IPC分类号: A61K31/50 , C07D209/54
CPC分类号: C07C229/60 , C07C317/44 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/79 , C07D213/80 , C07D213/84 , C07D213/85 , C07D257/04 , C07D401/04 , C07D401/12
摘要: The present invention provides a compound of formula (I): pharmaceutical compositions thereof, and methods of using the same, processes for preparing the same, and intermediates thereof.
摘要翻译: 本发明提供式(I)化合物:其药物组合物及其使用方法,其制备方法及其中间体。
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公开(公告)号:US20080139505A1
公开(公告)日:2008-06-12
申请号:US11718753
申请日:2005-11-15
申请人: Thomas Daniel Aicher , Guillermo S. Cortez , Todd Michael Groendyke , Albert Khilevich , James Allen Knobelsdorf , Fredrik Pehr Marmsater , Jeffrey Michael Schkeryantz , Tony Pisal Tang , Nicholas Andrew Magnus
发明人: Thomas Daniel Aicher , Guillermo S. Cortez , Todd Michael Groendyke , Albert Khilevich , James Allen Knobelsdorf , Fredrik Pehr Marmsater , Jeffrey Michael Schkeryantz , Tony Pisal Tang , Nicholas Andrew Magnus
IPC分类号: A61K31/19 , C07D309/00 , A61K31/695 , A61K31/35 , C07C255/00 , A61K31/24 , C07D401/00 , C07D211/78 , C07D239/02 , C07D333/24 , A61K31/381 , A61K31/425 , C07D277/00 , A61K31/505 , C07D271/06 , A61K31/44 , C07C229/00 , A61K31/275 , A61K31/41 , C07D257/04 , C07C63/04
CPC分类号: C07C229/60 , C07C317/44 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/79 , C07D213/80 , C07D213/84 , C07D213/85 , C07D257/04 , C07D401/04 , C07D401/12
摘要: The present invention provides compounds of formula (I): pharmaceutical compositions thereof, and methods of using the same, processes or preparing the same, and intermediates thereof.
摘要翻译: 本发明提供式(I)化合物:其药物组合物及其使用方法,方法或制备方法及其中间体。
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公开(公告)号:US07858646B2
公开(公告)日:2010-12-28
申请号:US11718446
申请日:2005-11-15
申请人: Thomas Daniel Aicher , Dana Rae Benesh , Maria-Jesus Blanco-Pillado , Guillermo S. Cortez , Todd Michael Groendyke , Albert Khilevich , James Allen Knobelsdorf , Fredrik Pehr Marmsäter , Jeffrey Michael Schkeryantz , Tony Pisal Tang
发明人: Thomas Daniel Aicher , Dana Rae Benesh , Maria-Jesus Blanco-Pillado , Guillermo S. Cortez , Todd Michael Groendyke , Albert Khilevich , James Allen Knobelsdorf , Fredrik Pehr Marmsäter , Jeffrey Michael Schkeryantz , Tony Pisal Tang
IPC分类号: C07D401/04 , C07D213/79 , A61K31/41 , A61K31/4439
CPC分类号: C07C229/60 , C07C317/44 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/79 , C07D213/80 , C07D213/84 , C07D213/85 , C07D257/04 , C07D401/04 , C07D401/12
摘要: The present invention provides compounds of formula (I); pharmaceutical compositions thereof, and methods of using the same, processes or preparing the same, and intermediates thereof.
摘要翻译: 本发明提供式(I)化合物; 其药物组合物及其使用方法,方法或制备方法及其中间体。
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