公开(公告)号：US11712339B2

公开(公告)日：2023-08-01

申请号：US17009610

申请日：2020-09-01

申请人： Titan Spine, Inc.

发明人： Michelle B. Gallagher ,  Mark E. Berg ,  Jennifer M. Schneider

IPC分类号： A61F2/30 ,  A61L27/00 ,  A61L27/06 ,  A61L27/50 ,  A61B17/58 ,  A61F2/28

CPC分类号： A61F2/30767 ,  A61B17/58 ,  A61F2/2846 ,  A61L27/06 ,  A61L27/50 ,  A61F2/3094 ,  A61F2002/3084 ,  A61F2002/3093 ,  A61F2002/3097 ,  A61F2002/30838 ,  A61F2002/30968 ,  A61F2002/30985 ,  A61L2400/18

摘要： An orthopedic implant having a titanium or titanium alloy body with a plurality of surfaces. The orthopedic implant is produced according to a process comprising the steps of: (a) additively building the orthopedic implant; and then (b) mechanically, chemically, or mechanically and chemically eroding one or more surfaces of the orthopedic implant to (i) remove alpha case from, and (ii) impart an osteoinducting roughness including micro-scale structures and nano-scale structures into, the one or more surfaces.

公开(公告)号：US11690723B2

公开(公告)日：2023-07-04

申请号：US16322373

申请日：2017-06-29

申请人： Titan Spine, Inc.

发明人： Michelle B. Gallagher ,  Mark E. Berg ,  Jennifer M. Schneider

IPC分类号： A61F2/30 ,  A61L27/06 ,  A61L27/50 ,  A61B17/58 ,  A61F2/28

CPC分类号： A61F2/30767 ,  A61B17/58 ,  A61F2/2846 ,  A61L27/06 ,  A61L27/50 ,  A61F2/3094 ,  A61F2002/3084 ,  A61F2002/3093 ,  A61F2002/3097 ,  A61F2002/30838 ,  A61F2002/30968 ,  A61F2002/30985 ,  A61L2400/18

摘要： Bone-contacting surfaces and free surfaces of orthopedic implants. The implants are additively manufactured, followed by mechanical, chemical, or mechanical and chemical erosion. At least some of the surfaces of the implants include an osteoinducting roughness that has micro-scale structures and nano-scale structures that facilitate and enhance osteoinduction and osteogenesis, as well as enhanced alkaline phosphatase, osterix, and osteocalcin expression levels along the pathway of mesenchymal stem cell differentiation to osteoblasts.

公开(公告)号：US20220355375A1

公开(公告)日：2022-11-10

申请号：US17853643

申请日：2022-06-29

申请人： Titan Spine, Inc.

发明人： Michelle B. Gallagher ,  Jennifer M. Schneider ,  Mark E. Berg

IPC分类号： B22F3/24 ,  A61L27/06 ,  A61F2/44 ,  B22F10/20 ,  B33Y10/00 ,  B33Y80/00 ,  A61F2/30

摘要： Orthopedic implants produced by additive manufacture, followed by refinement of exterior and interior surfaces trough mechanical erosion, chemical erosion, or a combination of mechanical and chemical erosion. Surface refinement removes debris, and also produces bone-growth enhancing micro-scale and nano-scale structures.

公开(公告)号：US11376660B2

公开(公告)日：2022-07-05

申请号：US15777435

申请日：2016-11-21

申请人： Titan Spine, Inc.

发明人： Michelle B. Gallagher ,  Jennifer M. Schneider ,  Mark E. Berg

IPC分类号： B22F3/24 ,  B22F3/105 ,  B33Y10/00 ,  C22C1/04 ,  B22F3/15 ,  A61L27/06 ,  A61F2/44 ,  B33Y80/00 ,  A61F2/30 ,  B22F10/20

摘要： Orthopedic implants produced by additive manufacture, followed by refinement of exterior and interior surfaces trough mechanical erosion, chemical erosion, or a combination of mechanical and chemical erosion. Surface refinement removes debris, and also produces bone-growth enhancing micro-scale and nano-scale structures.

公开(公告)号：US20200289284A1

公开(公告)日：2020-09-17

申请号：US16867959

申请日：2020-05-06

申请人： Titan Spine, Inc.

发明人： Peter F. Ullrich, JR. ,  Chad J. Patterson ,  Eric Kennedy ,  Carmie A. Thompson, III

IPC分类号： A61F2/44 ,  A61F2/30

摘要： Implants for vertebral body or functional spinal unit replacement comprise a bioactive surface roughening on one or more of the anterior, posterior, and lateral surfaces of the implant. The bioactive surface includes macro-, micro-, and nano-scale structural features that contact vertebral bone that lines a specialized channel in a vertebrae, and thereby facilitate bone growth and osteointegration of the implant with the vertebral bone.

公开(公告)号：US20190192312A1

公开(公告)日：2019-06-27

申请号：US16195516

申请日：2018-11-19

申请人： Titan Spine, Inc.

发明人： Peter F. Ullrich, JR. ,  Kenneth Roggow ,  Pablo Polanco

IPC分类号： A61F2/46 ,  A61F2/44 ,  A61F2/30

CPC分类号： A61F2/4611 ,  A61F2/30771 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/447 ,  A61F2002/30133 ,  A61F2002/30331 ,  A61F2002/30364 ,  A61F2002/30365 ,  A61F2002/30426 ,  A61F2002/30476 ,  A61F2002/30538 ,  A61F2002/3054 ,  A61F2002/30543 ,  A61F2002/3082 ,  A61F2002/30879 ,  A61F2002/3093 ,  A61F2002/4475 ,  A61F2002/4615 ,  A61F2002/4622 ,  A61F2002/4623 ,  A61F2002/4624 ,  A61F2002/4628 ,  A61F2002/4642 ,  A61F2002/4681

摘要： A system for use during surgical procedures. The system includes an implant and an inserter. The implant has a faceted post that rotates, ribs adapted to receive impact from an instrument to help position the implant, and stops. The inserter has a sleeve, into and from which a hook retracts and extends and on which a tab is disposed, and a pair of catches. The hook and tab combine to lock the post into position and to release the post so that the post can rotate. The engagements between the hook and the post and between the tab and the post permit rotation of the implant in situ. The stops and catches define an articulation range for the implant relative to a longitudinal axis of the inserter. A related method of using the system is also provided.

公开(公告)号：US20240189111A1

公开(公告)日：2024-06-13

申请号：US18583441

申请日：2024-02-21

申请人： TITAN SPINE, INC.

发明人： Peter F. Ullrich, JR. ,  Eric Kennedy ,  Charles J. Turner

IPC分类号： A61F2/44 ,  A61B17/02 ,  A61F2/30 ,  A61F2/46

CPC分类号： A61F2/4465 ,  A61F2/4455 ,  A61F2/4611 ,  A61B2017/0256 ,  A61F2002/30224 ,  A61F2002/30235 ,  A61F2002/30261 ,  A61F2002/30383 ,  A61F2002/30481 ,  A61F2002/30487 ,  A61F2002/30537 ,  A61F2002/3055 ,  A61F2002/30556 ,  A61F2002/30593 ,  A61F2002/30601 ,  A61F2002/30604 ,  A61F2002/30772 ,  A61F2002/30828 ,  A61F2/442 ,  A61F2/447 ,  A61F2/4603 ,  A61F2002/4622 ,  A61F2002/4628 ,  A61F2/4637 ,  A61F2220/0025

摘要： A system for use during surgical procedures. The system includes an implant and a tool. The implant combines a modular adjustable cage and a shim that locks the cage into position, after the cage has been adjusted to its final position and at its final height, in situ. The tool combines an expander and an inserter. A related method of using the system is also provided.

公开(公告)号：US11510786B2

公开(公告)日：2022-11-29

申请号：US16867959

申请日：2020-05-06

申请人： Titan Spine, Inc.

发明人： Peter F. Ullrich, Jr. ,  Chad J. Patterson ,  Eric Kennedy ,  Carmie A. Thompson, III

IPC分类号： A61F2/44 ,  A61F2/30

摘要： Implants for vertebral body or functional spinal unit replacement comprise a bioactive surface roughening on one or more of the anterior, posterior, and lateral surfaces of the implant. The bioactive surface includes macro-, micro-, and nano-scale structural features that contact vertebral bone that lines a specialized channel in a vertebrae, and thereby facilitate bone growth and osteointegration of the implant with the vertebral bone.

公开(公告)号：US11370025B2

公开(公告)日：2022-06-28

申请号：US15777345

申请日：2016-11-21

申请人： Titan Spine, Inc.

发明人： Michelle B. Gallagher ,  Jennifer M. Schneider ,  Mark E. Berg

IPC分类号： B22F3/24 ,  C22C1/04 ,  B33Y10/00 ,  B33Y40/00 ,  A61L27/04 ,  B24C3/32 ,  B22F10/00 ,  B24C11/00 ,  B24C1/00 ,  A61L27/06 ,  B22F5/10 ,  B22F10/20

摘要： Orthopedic implants produced by additive manufacture, followed by refinement of exterior and interior surfaces trough mechanical erosion, chemical erosion, or a combination of mechanical and chemical erosion. Surface refinement removes debris, and also produces bone-growth enhancing micro-scale and nano-scale structures.

公开(公告)号：US20220000638A1

公开(公告)日：2022-01-06

申请号：US17476640

申请日：2021-09-16

申请人： Titan Spine, Inc.

发明人： Peter F. Ullrich, JR. ,  Eric Kennedy ,  Charles J. Turner

IPC分类号： A61F2/44 ,  A61F2/46

摘要： A system for use during surgical procedures. The system includes an implant and a tool. The implant combines a modular adjustable cage and a shim that locks the cage into position, after the cage has been adjusted to its final position and at its final height, in situ. The tool combines an expander and an inserter. A related method of using the system is also provided.