Compounds and method for synthesizing sulfoindocyanine dyes
    3.
    发明授权
    Compounds and method for synthesizing sulfoindocyanine dyes 失效
    磺酰吲哚菁染料的化合物和方法

    公开(公告)号:US5767287A

    公开(公告)日:1998-06-16

    申请号:US869032

    申请日:1997-06-04

    CPC分类号: C09B23/02 C07D209/14

    摘要: Novel intermediates having an indolenine nucleus which are useful in the synthesis of fluorescent sulfoindocyanine dyes are described. Dyes synthesized using such intermediates do not contain a reactive group that will covalently attach to a target molecule at an amine- or hydroxy-containing site. Rather, these intermediates are linked to an enzyme substrate or a member of a specific binding pair. Also included are tyramide-containing sulfonidocyanine dyes.

    摘要翻译: 描述了可用于合成荧光磺基吲哚菁染料的具有吲哚宁核的新型中间体。 使用这种中间体合成的染料不含有将在含胺或羟基的位点共价连接到靶分子上的反应性基团。 相反,这些中间体连接到酶底物或特异性结合对的成员。 还包括含有酪酰胺的磺胺蓝染料。

    Compounds and method for synthesizing sulfoindocyanine dyes
    4.
    发明授权
    Compounds and method for synthesizing sulfoindocyanine dyes 失效
    磺酰吲哚菁染料的化合物和方法

    公开(公告)号:US5688966A

    公开(公告)日:1997-11-18

    申请号:US687853

    申请日:1996-07-26

    CPC分类号: C09B23/02 C07D209/14

    摘要: Novel intermediates having an indolenine nucleus which are useful in the synthesis of fluorescent sulfoindocyanine dyes are described. Dyes synthesized using such intermediates do not contain a reactive group that will covalently attach to a target molecule at an amine- or hydroxy-containing site. Rather, these intermediates are linked to an enzyme substrate or a member of a specific binding pair. Also included are tyramide-comaining sulfonidocyanine dyes.

    摘要翻译: 描述了可用于合成荧光磺基吲哚菁染料的具有吲哚宁核的新型中间体。 使用这种中间体合成的染料不含有将在含胺或羟基的位点共价连接到靶分子上的反应性基团。 相反,这些中间体连接到酶底物或特异性结合对的成员。 还包括酪酰胺接枝磺胺蓝染料。