专利检索 ap:"THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORA" 第 1 页

1.

发明申请
METHODS AND COMPOUNDS FOR TREATING MALARIA 审中-公开

公开(公告)号：US20190030056A1

公开(公告)日：2019-01-31

申请号：US16071459

申请日：2017-01-23

申请人： THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORA , WASHINGTON UNIVERSITY IN ST. LOUIS

发明人： Cynthia DOWD , Audrey ODOM , Rachel Edwards , Robert BROTHERS

IPC分类号： A61K31/7056 , A61P33/06 , A61K31/122 , A61K31/137 , A61K31/357 , A61K31/366 , A61K31/437 , A61K31/4706 , A61K31/496 , A61K31/65

CPC分类号： A61K31/7056 , A61K31/122 , A61K31/137 , A61K31/155 , A61K31/357 , A61K31/366 , A61K31/437 , A61K31/4706 , A61K31/49 , A61K31/496 , A61K31/519 , A61K31/65 , A61K31/683 , A61K45/06 , A61P33/06 , Y02A50/411 , A61K2300/00

摘要： A pharmaceutical composition includes a small molecule and a pharmaceutically acceptable excipient. The small molecule interacts with a deoxyxylulose phosphate reductoisomerase (Dxr). A method for treating or preventing a microbial infection in a subject in need thereof includes administering the pharmaceutical composition. A method for inhibiting the growth of a eukaryotic pathogen includes contacting the eukaryotic pathogen with an effective amount of the pharmaceutical composition.