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    STENTS MODIFIED WITH MATERIAL COMPRISING AMNION TISSUE AND CORRESPONDING PROCESSES
    2.
    发明申请
    STENTS MODIFIED WITH MATERIAL COMPRISING AMNION TISSUE AND CORRESPONDING PROCESSES 有权
    用包含粘结组织和相应工艺的材料修改的手套

    公开(公告)号：US20100228335A1

    公开(公告)日：2010-09-09

    申请号：US12713666

    申请日：2010-02-26

    申请人： John Schorgl ,  Paul Thompson ,  Steven J. Healy ,  Robert Thatcher

    发明人： John Schorgl ,  Paul Thompson ,  Steven J. Healy ,  Robert Thatcher

    IPC分类号： A61F2/82 ,  B05D7/00

    CPC分类号： A61L31/005 ,  A61F2/062 ,  A61F2/07 ,  A61F2/82 ,  A61F2/86 ,  A61F2002/065 ,  A61F2210/0076 ,  A61F2220/0025 ,  A61F2220/0066 ,  A61F2310/00982 ,  A61L27/3604 ,  A61L27/3813 ,  A61L27/3834 ,  A61L27/507 ,  A61L31/08 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/30 ,  A61L2300/412 ,  A61L2300/64 ,  A61L2400/18

    摘要： A stent scaffold combined with amniotic tissue provides for a biocompatible stent that has improved biocompatibility and hemocompatibility. The amnion tissue can be variously modified or unmodified form of amnion tissue such as non-cryo amnion tissue, solubilized amnion tissue, amnion tissue fabric, chemically modified amnion tissue, amnion tissue treated with radiation, amnion tissue treated with heat, or a combination thereof. Materials such as polymer, placental tissue, pericardium tissue, small intestine submucosa can be used in combination with the amnion tissue. The amnion tissue can be attached to the inside, the outside, both inside and outside, or complete encapsulation of the stent scaffold. In some embodiments, at least part of the covering or lining comprises a plurality of layers of amnion tissue. The method of making the biocompatible stent and its delivery and deployment are also discussed.

    摘要翻译： 与羊膜组织结合的支架支架提供具有改善的生物相容性和血液相容性的生物相容性支架。 羊膜组织可以是羊膜组织的各种修饰或未修饰形式，例如非低温羊膜组织，溶解的羊膜组织，羊膜组织织物，化学修饰的羊膜组织，用辐射处理的羊膜组织，用热处理的羊膜组织或其组合 。 诸如聚合物，胎盘组织，心包组织，小肠粘膜下层的材料可以与羊膜组织结合使用。 羊膜组织可以连接到内部，外部，内部和外部，或完全包封支架支架。 在一些实施例中，覆盖物或衬里的至少一部分包括多层羊膜织物。 还讨论了制备生物相容性支架及其递送和部署的方法。

    Apparatus for deploying body implantable stents
    3.
    发明授权
    Apparatus for deploying body implantable stents 失效
    用于部署身体可植入支架的装置

    公开(公告)号：US06380457B1

    公开(公告)日：2002-04-30

    申请号：US08958066

    申请日：1997-10-27

    申请人： Matthew T. Yurek ,  Steven J. Healy

    发明人： Matthew T. Yurek ,  Steven J. Healy

    IPC分类号： A61F202

    CPC分类号： A61F2/958 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9583 ,  A61F2002/9665

    摘要： A stent deployment device includes a flexible, elongate interior catheter and a retaining structure cooperating with the catheter to support a stent along a distal end support region of the catheter. The stent is supported in a reduced radius delivery state to facilitate delivery to a treatment site in a body lumen, by advancing the device over a previously positioned guidewire. An opening at the distal end of the device receives the guidewire into a guidewire lumen of the interior catheter. A second opening through the catheter wall just proximally of the support region allows passage of the guidewire to the exterior of the catheter, whereby the guidewire is contained within the device only along the distal end region. The retaining structure can include an exterior catheter surrounding the interior catheter and stent, and moveable axially relative to the interior catheter. A portion of the guidewire proximally of the second opening is contained between the catheters, and can be removed from the exterior catheter through a slit running axially along the exterior catheter.

    摘要翻译： 支架展开装置包括柔性细长的内部导管和与导管配合的保持结构，以沿着导管的远端支撑区域支撑支架。 通过将装置推进在先前定位的导丝上，支架以减小的半径递送状态被支撑以便于输送到体腔内的治疗部位。 设备远端处的开口将导丝接纳到内导管的导丝管腔中。 通过靠近支撑区域的导管壁的第二开口允许导丝通过导管的外部，由此导丝仅沿着远端区域容纳在装置内。 保持结构可以包括围绕内部导管和支架的外部导管，并且可相对于内部导管轴向移动。 在第二开口的近侧的导丝的一部分被容纳在导管之间，并且可以通过沿着外部导管轴向运动的狭缝从外部导管移除。

    Apparatus for deploying body implantable stent
    5.
    发明授权
    Apparatus for deploying body implantable stent 失效
    用于部署植入式支架的装置

    公开(公告)号：US5690644A

    公开(公告)日：1997-11-25

    申请号：US603683

    申请日：1996-02-20

    申请人： Matthew T. Yurek ,  Steven J. Healy

    发明人： Matthew T. Yurek ,  Steven J. Healy

    IPC分类号： A61F2/82 ,  A61F2/06 ,  A61F2/84 ,  A61M25/12 ,  A61F11/00 ,  A61M29/00

    CPC分类号： A61F2/958 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9583 ,  A61F2002/9665

    摘要： A stent deployment device includes a flexible, elongate interior catheter and a retaining structure cooperating with the catheter to support a stent along a distal end support region of the catheter. The stent is supported in a reduced radius delivery state to facilitate delivery to a treatment site in a body lumen, by advancing the device over a previously positioned guidewire. An opening at the distal end of the device receives the guidewire into a guidewire lumen of the interior catheter. A second opening through the catheter wall just proximally of the support region allows passage of the guidewire to the exterior of the catheter, whereby the guidewire is contained within the device only along the distal end region. A retainer for the stent can include an exterior catheter surrounding the interior catheter and stent, and moveable axially relative to the interior catheter. A portion of the guidewire proximally of the second opening is contained between the catheters, and can be removed from the exterior catheter through a slit running axially along the exterior catheter. Alternatively, the stent retainer can include a pair of spaced apart sleeves integral with the interior catheter and frictionally retaining opposite ends of the stent, to maintain the stent in the delivery state. In this case the catheter further supports a dilatation balloon surrounded by the stent. The balloon is expanded to free the stent from the sleeves.

    摘要翻译： 支架展开装置包括柔性细长的内部导管和与导管配合的保持结构，以沿着导管的远端支撑区域支撑支架。 通过将装置推进在先前定位的导丝上，支架以减小的半径递送状态被支撑以便于输送到体腔内的治疗部位。 设备远端处的开口将导丝接纳到内导管的导丝管腔中。 通过靠近支撑区域的导管壁的第二开口允许导丝通过导管的外部，由此导丝仅沿着远端区域容纳在装置内。 用于支架的保持器可以包括围绕内部导管和支架的外部导管，并且可相对于内部导管轴向移动。 在第二开口的近侧的导丝的一部分被容纳在导管之间，并且可以通过沿着外部导管轴向运动的狭缝从外部导管移除。 或者，支架保持器可以包括与内部导管成一体并且摩擦地保持支架的相对端的一对间隔开的套筒，以将支架保持在输送状态。 在这种情况下，导管还支撑由支架包围的扩张气囊。 将气囊膨胀以从袖子释放支架。

    Apparatus for deploying body implantable stents
    6.
    发明授权
    Apparatus for deploying body implantable stents 失效
    用于部署身体可植入支架的装置

    公开(公告)号：US06755855B2

    公开(公告)日：2004-06-29

    申请号：US10100944

    申请日：2002-03-19

    申请人： Matthew T. Yurek ,  Steven J. Healy

    发明人： Matthew T. Yurek ,  Steven J. Healy

    IPC分类号： A61F206

    CPC分类号： A61F2/958 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9583 ,  A61F2002/9665

    摘要： A stent deployment device includes a flexible, elongate interior catheter and a retaining structure cooperating with the catheter to support a stent along a distal end support region of the catheter. The stent is supported in a reduced radius delivery state to facilitate delivery to a treatment site in a body lumen, by advancing the device over a previously positioned guidewire. An opening at the distal end of the device receives the guidewire into a guidewire lumen of the interior catheter. A second opening through the catheter wall just proximally of the support region allows passage of the guidewire to the exterior of the catheter, whereby the guidewire is contained within the device only along the distal end region. The retaining structure can include an exterior catheter surrounding the interior catheter and stent, and moveable axially relative to the interior catheter. A portion of the guidewire proximally of the second opening is contained between the catheters, and can be removed from the exterior catheter through a slit running axially along the exterior catheter. Alternatively, the retaining means can include a pair of spaced apart sleeves integral with the interior catheter and frictionally retaining opposite ends of the stent, to maintain the stent in the delivery state. In this case the catheter further supports a dilatation balloon surrounded by the stent. The balloon is expanded to free the stent from the sleeves.

    摘要翻译： 支架展开装置包括柔性细长的内部导管和与导管配合的保持结构，以沿着导管的远端支撑区域支撑支架。 通过将装置推进在先前定位的导丝上，支架以减小的半径递送状态被支撑以便于输送到体腔内的治疗部位。 设备远端处的开口将导丝接纳到内导管的导丝管腔中。 通过靠近支撑区域的导管壁的第二开口允许导丝通过导管的外部，由此导丝仅沿着远端区域容纳在装置内。 保持结构可以包括围绕内部导管和支架的外部导管，并且可相对于内部导管轴向移动。 在第二开口的近侧的导丝的一部分被容纳在导管之间，并且可以通过沿着外部导管轴向运动的狭缝从外部导管移除。 或者，保持装置可以包括与内部导管成一体的一对间隔开的套筒，并摩擦地保持支架的相对端部，以将支架保持在输送状态。 在这种情况下，导管还支撑由支架包围的扩张气囊。 将气囊膨胀以从袖子释放支架。