Sheet conductance/resistance measurement system

    公开(公告)号:US08428706B2

    公开(公告)日:2013-04-23

    申请号:US11595306

    申请日:2006-11-10

    IPC分类号: A61B5/00

    摘要: An apparatus for testing of electrical or physical properties of a material include a single coil sensor mounted adjacent to a sample of the material. Sheet conductance of a wide variety of materials may be measured using the single coil to determine if the material conforms to generally accepted standards for the use to which the material will be put. In some examples, the material is a semiconductor wafer or flat panel. In other examples, the material is the body tissue of a patient. A non-invasive technique using the apparatus is also disclosed for monitoring the health of patient tissue such as musculature, and/or to determine whether healthy circulation is present, by measuring the conductance of the patient tissue in response to a magnetic field applied by the single coil. The single coil may be hand held, or it may be movable using an automated positioning system under computer control.

    Stress urinary incontinence implant and device for deploying same
    3.
    发明申请
    Stress urinary incontinence implant and device for deploying same 有权
    压力性尿失禁植入物及其部署装置

    公开(公告)号:US20070156012A1

    公开(公告)日:2007-07-05

    申请号:US11321659

    申请日:2005-12-29

    IPC分类号: A61F2/02

    摘要: A suburethral implant for treating stress urinary incontinence (SUI) includes an elongated plate-like member which is slightly curved in transverse cross-section, and a pair of spaced apart arms having hooked ends or barbs which extend from the plate-like member. A device for deploying the suburethral implant for treating SUI includes a vaginal probe for insertion in the vaginal canal of a patient, and a urethra locator probe for the simultaneous insertion in the urethra of a patient. The urethra probe is spaced apart from and overlies the vaginal probe. The vaginal probe includes a wall in which is formed an exit port. A suburethral implant introducer assembly is extendable and retractable through the exit port on the vaginal probe. The introducer assembly has a distal end on which is removably mounted a suburethral implant. The introducer assembly is extendable through the exit port to pierce the vaginal canal wall of the patient in order to position the suburethral implant in proximity to the patient's urethra. The hooked ends or barbs on the arms of the suburethral implant engage the tissue surrounding the patient's urethra and are affixed thereto during deployment of the implant. The introducer assembly is then retracted into the vaginal probe, whereby the implant is released from the introducer assembly and remains affixed to tissue in proximity to the patient's urethra.

    摘要翻译: 用于治疗压力性尿失禁的尿道植入物(SUI)包括在横截面上略微弯曲的细长板状构件,以及一对间隔开的臂,其具有从板状构件延伸的钩端或倒钩。 用于部署用于治疗SUI的尿道植入物的装置包括用于插入患者阴道内的阴道探针和用于同时插入患者尿道的尿道定位器探针。 尿道探针与阴道探针间隔开并覆盖阴道探针。 阴道探针包括形成有出口的壁。 尿道植入物导引器组件可以通过阴道探针上的出口延伸和缩回。 导引器组件具有远端,其上可移除地安装有尿道植入物。 导引器组件可通过出口延伸以刺穿患者的阴道管壁,以将尿道植入物定位在患者的尿道附近。 尿道植入物的手臂上的钩状端或倒钩与患者尿道周围的组织接合,并在植入物展开过程中固定在其上。 导引器组件然后缩回到阴道探针中,由此植入物从导引器组件释放并且保持附着于患者尿道附近的组织。

    Sheet conductance/resistance measurement system
    5.
    发明申请
    Sheet conductance/resistance measurement system 有权
    片材电导/电阻测量系统

    公开(公告)号:US20070108972A1

    公开(公告)日:2007-05-17

    申请号:US11595306

    申请日:2006-11-10

    IPC分类号: G01R33/12

    摘要: An apparatus for testing of electrical or physical properties of a material include a single coil sensor mounted adjacent to a sample of the material. Sheet conductance of a wide variety of materials may be measured using the single coil to determine if the material conforms to generally accepted standards for the use to which the material will be put. In some examples, the material is a semiconductor wafer or flat panel. In other examples, the material is the body tissue of a patient. A non-invasive technique using the apparatus is also disclosed for monitoring the health of patient tissue such as musculature, and/or to determine whether healthy circulation is present, by measuring the conductance of the patient tissue in response to a magnetic field applied by the single coil. The single coil may be hand held, or it may be movable using an automated positioning system under computer control.

    摘要翻译: 用于测试材料的电学或物理性质的装置包括邻近材料样品安装的单个线圈传感器。 可以使用单个线圈测量各种材料的片材电导,以确定材料是否符合通常接受的材料使用标准。 在一些示例中,材料是半导体晶片或平板。 在其他实例中,材料是患者的身体组织。 还公开了使用该装置的非侵入性技术,用于通过响应于由所述装置施加的磁场来测量患者组织的电导,来监测患者组织的健康,例如肌肉组织和/或确定是否存在健康的循环 单线圈 单个线圈可以是手持的,或者可以在计算机控制下使用自动定位系统来移动。

    Therapeutic calcium phosphate particles for use in inhibiting expression of a gene
    6.
    发明申请
    Therapeutic calcium phosphate particles for use in inhibiting expression of a gene 审中-公开
    用于抑制基因表达的治疗性磷酸钙颗粒

    公开(公告)号:US20060062855A1

    公开(公告)日:2006-03-23

    申请号:US11195479

    申请日:2005-08-02

    申请人: Steve Bell

    发明人: Steve Bell

    IPC分类号: A61K48/00 C12N15/87 A61K9/50

    摘要: Novel calcium phosphate core particles, methods of making them, and methods of using them as carriers of biologically active material and controlled release matrices for biologically active material are disclosed. The core particles may have a surface modifying agent and/or biologically active material, such as polynucleotide material partially coating the particle or impregnated therein or both. The particles may be used to carry polynucleotide (or oligonucleotide) material that is complementary to a sequence of mRNA that binds to or ligates with and inhibits the expression of particular genes (by blocking translation of the mRNA sequence). The core particles are substantially spherical in shape, and have a substantially smooth surface.

    摘要翻译: 公开了新型磷酸钙核心颗粒,其制备方法以及将其用作生物活性材料的载体和用于生物活性材料的控制释放基质的方法。 核心颗粒可以具有表面改性剂和/或生物活性材料,例如部分涂覆颗粒或浸渍在其中或两者的多核苷酸材料。 颗粒可以用于携带与结合或连接的mRNA序列互补的多核苷酸(或寡核苷酸)材料,并且通过阻断mRNA序列的翻译来抑制特定基因的表达。 核心颗粒的形状基本上是球形,并且具有基本平滑的表面。

    Stress urinary incontinence implant and device for deploying same
    7.
    发明授权
    Stress urinary incontinence implant and device for deploying same 有权
    压力性尿失禁植入物及其部署装置

    公开(公告)号:US07942806B2

    公开(公告)日:2011-05-17

    申请号:US11321659

    申请日:2005-12-29

    IPC分类号: A61F2/00

    摘要: A suburethral implant for treating stress urinary incontinence (SUI) includes an elongated plate-like member which is slightly curved in transverse cross-section, and a pair of spaced apart arms having hooked ends or barbs which extend from the plate-like member. A device for deploying the suburethral implant for treating SUI includes a vaginal probe for insertion in the vaginal canal of a patient, and a urethra locator probe for the simultaneous insertion in the urethra of a patient. The urethra probe is spaced apart from and overlies the vaginal probe. The vaginal probe includes a wall in which is formed an exit port. A suburethral implant introducer assembly is extendable and retractable through the exit port on the vaginal probe. The introducer assembly has a distal end on which is removably mounted a suburethral implant. The introducer assembly is extendable through the exit port to pierce the vaginal canal wall of the patient in order to position the suburethral implant in proximity to the patient's urethra. The hooked ends or barbs on the arms of the suburethral implant engage the tissue surrounding the patient's urethra and are affixed thereto during deployment of the implant. The introducer assembly is then retracted into the vaginal probe, whereby the implant is released from the introducer assembly and remains affixed to tissue in proximity to the patient's urethra.

    摘要翻译: 用于治疗压力性尿失禁的尿道植入物(SUI)包括在横截面上略微弯曲的细长板状构件,以及一对间隔开的臂,其具有从板状构件延伸的钩端或倒钩。 用于部署用于治疗SUI的尿道植入物的装置包括用于插入患者阴道内的阴道探针和用于同时插入患者尿道的尿道定位器探针。 尿道探针与阴道探针间隔开并覆盖阴道探针。 阴道探针包括形成有出口的壁。 尿道植入物导引器组件可以通过阴道探针上的出口延伸和缩回。 导引器组件具有远端,其上可移除地安装有尿道植入物。 导引器组件可通过出口延伸以刺穿患者的阴道管壁,以将尿道植入物定位在患者的尿道附近。 尿道植入物的手臂上的钩状端或倒钩与患者尿道周围的组织接合,并在植入物展开过程中固定在其上。 导引器组件然后缩回到阴道探针中,由此植入物从导引器组件释放并且保持附着于患者尿道附近的组织。