-
公开(公告)号：US6010697A
公开(公告)日：2000-01-04
申请号：US141441
申请日：1998-08-27
申请人： Stephen L. Smith , Xiaoying Qiao , Susan M. Maciukas , Maureen F. Loudovaris , James G. Bender , Dennis E. Van Epps
发明人： Stephen L. Smith , Xiaoying Qiao , Susan M. Maciukas , Maureen F. Loudovaris , James G. Bender , Dennis E. Van Epps
IPC分类号： A61K35/12 , C12N5/078 , C12N5/0787 , C12N5/00
CPC分类号： C12N5/0644 , C12N5/0642 , A61K35/12 , C12N2500/25 , C12N2500/36 , C12N2500/44 , C12N2500/90 , C12N2501/125 , C12N2501/22 , C12N2501/23 , C12N2501/39
摘要： The invention provides a method of treating a patient having a reduced population of neutrophils following a myeloablative cancer treatment such as high dose chemotherapy. Following myeloablative therapy, a cell composition of at least 25% neutrophil precursors, i.e. promyelocytes, myelocytes, and metamyelocytes, is administered to the patient. Thereafter, the neutrophil precursors differentiate rapidly in vivo to replenish the supply of mature neutrophils for fighting infection. The method is used to reduce the neutropenic window between the time of myeloablative therapy and the time required for infused stem cells to proliferate and differentiate into mature neutrophils.
摘要翻译： 本发明提供了一种治疗患有嗜中性粒细胞减少的患者的方法，所述患者在诸如高剂量化学疗法的骨髓切除癌症治疗之后。 在清髓疗法之后，向患者施用至少25％嗜中性粒细胞前体，即前髓细胞，骨髓细胞和间皮细胞的细胞组合物。 此后，嗜中性粒细胞前体在体内迅速分化，以补充成熟嗜中性粒细胞供应以抵抗感染。 该方法用于减少清髓性治疗时间与输注的干细胞增殖和分化成成熟嗜中性粒细胞所需的时间之间的中性粒细胞筛选窗口。
-
2.发明授权Multilayer gas-permeable container for the culture of adherent and non-adherent cells 失效用于粘附和非贴壁细胞培养的多层透气容器
公开(公告)号：US5935847A
公开(公告)日：1999-08-10
申请号：US72127
申请日：1998-05-04
申请人： Sidney T. Smith , David V. Bacehowski , William Kolanko , Larry Rosenbaum , Stephen L. Smith , James G. Bender , Lecon Woo , Michael T. K. Ling
发明人： Sidney T. Smith , David V. Bacehowski , William Kolanko , Larry Rosenbaum , Stephen L. Smith , James G. Bender , Lecon Woo , Michael T. K. Ling
CPC分类号： C12M23/14 , C12M23/20 , C12M23/24 , Y10T428/1334 , Y10T428/24975 , Y10T428/31909 , Y10T428/31913 , Y10T428/3192
摘要： A multi-layer, flexible, gas-permeable film (10) suitable for forming a cell culture container (20), the film (10) comprising a first layer (12) composed of a polystyrene having a thickness within the range of 0.0001 inches to about 0.0010 inches and, a second layer (14) adhered to the first layer (12) composed of a polymer material having a thickness within the range of 0.004 inches to about 0.025 inches.
摘要翻译： 一种适用于形成细胞培养容器（20）的多层柔性透气膜（10），所述膜（10）包括由厚度在0.0001英寸范围内的聚苯乙烯构成的第一层（12） 至约0.0010英寸，以及粘附到由厚度在0.004英寸至约0.025英寸范围内的聚合物材料构成的第一层（12）的第二层（14）。
-
公开(公告)号：US5797350A
公开(公告)日：1998-08-25
申请号：US838578
申请日：1997-04-10
申请人： Stephen L. Smith
发明人： Stephen L. Smith
摘要： An enclosure for small animals, such as rodents, is described wherein the enclosure is constructed of various component parts. The component parts of the enclosure can be easily replaced when either damaged or destroyed, thus eliminating the need to replace the entire enclosure. The enclosure can also be rapidly assembled and disassembled without the need for any tools or mechanical ability. The enclosure's component parts may be constructed of any suitable thermoplastic material, wherein the thermoplastic material can be either opaque, translucent, or transparent.
摘要翻译： 描述了用于小动物（例如啮齿动物）的外壳，其中外壳由各种部件构成。 外壳的组件可以在损坏或损坏时轻松更换，从而无需更换整个外壳。 外壳也可以快速组装和拆卸，无需任何工具或机械能力。 外壳的部件可以由任何合适的热塑性材料制成，其中热塑性材料可以是不透明的，半透明的或透明的。
-
公开(公告)号：US20130266452A1
公开(公告)日：2013-10-10
申请号：US13438877
申请日：2012-04-04
申请人： Stephen L. Smith
发明人： Stephen L. Smith
CPC分类号： B64C11/26 , Y10T29/49826 , Y10T29/4998
摘要： A propeller blade spar core includes a leading edge spar foam section surrounded by a first structural layer, a trailing edge spar foam surrounded by a second structural layer, and a third structural layer surrounding both the first and second structural layers.
摘要翻译： 推进器叶片翼梁芯包括由第一结构层围绕的前缘翼梁泡沫部分，由第二结构层包围的后缘翼梁泡沫以及围绕第一和第二结构层的第三结构层。
-
5.发明申请公开(公告)号：US20110200577A1
公开(公告)日：2011-08-18
申请号：US12987531
申请日：2011-01-10
申请人： Stephen L. Smith , Loredana Campo , Jennifer Campbell , Shiri Uriel Wallach , Wanda Seyton , Shane Donovan
发明人： Stephen L. Smith , Loredana Campo , Jennifer Campbell , Shiri Uriel Wallach , Wanda Seyton , Shane Donovan
CPC分类号： A61K38/18 , A61K38/195 , A61K38/363 , A61K38/4833 , A61L24/0015 , A61L24/106 , A61L2300/252 , A61K38/00
摘要： The invention relates to a pharmaceutical composition which comprises a fibrin clot and a cytokine and methods of delivering the composition to a site of disease or injury in vivo to attract and retain regenerative or reparative stem or myeloid cells and their differentiated progeny.
摘要翻译： 本发明涉及一种药物组合物，其包含纤维蛋白凝块和细胞因子以及将组合物递送至体内疾病或损伤部位以吸引和保留再生或修复性干细胞或骨髓细胞及其分化后代的方法。
-
6.发明授权Multilayer gas-permeable container for the culture of adherent and non-adherent cells 失效用于粘附和非贴壁细胞培养的多层透气容器公开(公告)号：US06297046B1
公开(公告)日：2001-10-02
申请号：US08330717
申请日：1994-10-28
申请人： Sidney T. Smith , David V. Bacehowski , William Kolanko , Larry Rosenbaum , Stephen L. Smith , James G. Bender , Lecon Woo , Michael T. K. Ling
发明人： Sidney T. Smith , David V. Bacehowski , William Kolanko , Larry Rosenbaum , Stephen L. Smith , James G. Bender , Lecon Woo , Michael T. K. Ling
IPC分类号： C12M306
摘要： A multi-layer, flexible, gas-permeable film (10) suitable for forming a cell culture container (20), the film (10) comprising a first layer (12) composed of a polystyrene having a thickness within the range of 0.0001 inches to about 0.0010 inches and, a second layer (14) adhered to the first layer (12) composed of a polyolefin having a thickness within the range of 0.004 inches to about 0.015 inches.
摘要翻译： 一种适用于形成细胞培养容器（20）的多层柔性透气膜（10），所述膜（10）包括由厚度在0.0001英寸范围内的聚苯乙烯构成的第一层（12） 至约0.0010英寸，以及粘附到由厚度在0.004英寸至约0.015英寸范围内的聚烯烃构成的第一层（12）的第二层（14）。
-
公开(公告)号：US5846529A
公开(公告)日：1998-12-08
申请号：US376945
申请日：1995-01-20
申请人： Stephen L. Smith , Xiaoying Qiao , Susan M. Maciukas , Maureen F. Loudovaris , James G. Bender , Dennis E. Van Epps
发明人： Stephen L. Smith , Xiaoying Qiao , Susan M. Maciukas , Maureen F. Loudovaris , James G. Bender , Dennis E. Van Epps
IPC分类号： A61K35/12 , C12N5/078 , C12N5/0787 , C12N5/00
CPC分类号： C12N5/0644 , C12N5/0642 , A61K35/12 , C12N2500/25 , C12N2500/36 , C12N2500/44 , C12N2500/90 , C12N2501/125 , C12N2501/22 , C12N2501/23 , C12N2501/39
摘要： The invention provides a method of treating a patient having a reduced population of neutrophils following a myeloablative cancer treatment such as high dose chemotherapy. Following myeloablative therapy, a cell composition of at least 25% neutrophil precursors, i.e. promyelocytes, myelocytes, and metamyelocytes, is administered to the patient. Thereafter, the neutrophil precursors differentiate rapidly in vivo to replenish the supply of mature neutrophils for fighting infection. The method is used to reduce the neutropenic window between the time of myeloablative therapy and the time required for infused stem cells to proliferate and differentiate into mature neutrophils.
-
公开(公告)号：US5726924A
公开(公告)日：1998-03-10
申请号：US680282
申请日：1996-07-11
申请人： John Michael Buss , James Douglas Dworkin , Scott Edward Lloyd , ShaoWei Pan , Stephen L. Smith , Shay-Ping Thomas Wang
发明人： John Michael Buss , James Douglas Dworkin , Scott Edward Lloyd , ShaoWei Pan , Stephen L. Smith , Shay-Ping Thomas Wang
CPC分类号： G06F7/556
摘要： A circuit and method for computing an exponential signal x.sup.g is provided. The circuit includes a logarithm converter which converts an input signal to binary word that represents the logarithm of an input signal x. A first shift register shifts the binary word in a bit-wise fashion to produce a first intermediate value; while a second shift register shifts the binary word in a bit-wise fashion to produce a second intermediate value. The shift registers may be implemented using multiplexers. The shifting operations are equivalent to multiplying the intermediate values by a factor which is a power of two. The first intermediate value is either added to or subtracted from the second intermediate value to produce a combined value. An inverse-logarithm converter converts the combined value to the exponential signal.
-
公开(公告)号：US5595517A
公开(公告)日：1997-01-21
申请号：US657065
申请日：1996-05-29
申请人： Stephen L. Smith
发明人： Stephen L. Smith
IPC分类号： B63H16/06
CPC分类号： B63H16/06
摘要： A support for boat oars to hold the oars in a fixed stationary and at rest position without the use of the rower's hands. The support is of particular use in a single sculling boat and consists of securing oar straps fastened to a bar. An overall riser rod assembly is formed by placing upper and lower riser rods on a connecting rod. The overall riser rod assembly is pivotally connected at one end to a plate attached to the bar and, at the other end, to a plate attached to a mounting bracket. The mounting bracket is fastened to the structure of the boat. The overall riser rod assembly can be adjusted in length to conform to various boats and rowers. The support is easily lowered to an out of the way location when not in use.
摘要翻译： 支持船桨将桨固定在静止和静止位置，而无需使用水手的手。 该支撑件在单个的刚性舟艇中特别有用，并且包括固定在杆上的桨带。 整个提升杆组件通过将上部和下部提升杆放置在连接杆上而形成。 整个提升杆组件在一端枢转地连接到附接到杆的板，并且在另一端枢转地连接到附接到安装支架的板。 安装支架固定在船的结构上。 整个提升杆组件的长度可以调整以符合各种船和划船者。 在不使用时，支撑件很容易降低到位置的位置。
-
公开(公告)号：US4464736A
公开(公告)日：1984-08-07
申请号：US421748
申请日：1982-09-23
申请人： Stephen L. Smith
发明人： Stephen L. Smith
CPC分类号： G11C29/789 , G11C16/08
摘要： An E.sup.2 PROM redundant memory element is provided whereby faulty or improperly coded ROM or E.sup.2 PROM elements may be replaced by the user in-package. An address programming element including an E.sup.2 PROM floating gate device having a programmed mode, an unprogrammed mode, and an inhibit mode, may be programmed and erased in-package. Addresses received by the redundant memory element in addition to other inputs determine the mode of the floating gate device.
摘要翻译： 提供了一种E2PROM冗余存储器元件，其中错误或不正确编码的ROM或E2PROM元件可以由用户在包装中替换。 包括具有编程模式，未编程模式和禁止模式的E2PROM浮动栅极器件的地址编程元件可以被编程和擦除在封装中。 除了其他输入之外，由冗余存储器元件接收的地址决定了浮动栅极器件的模式。
-
-
-
-
-
-
-
-
-
搜索结果
32 条记录 (耗时 0.024 秒)
