公开(公告)号：US09925118B2

公开(公告)日：2018-03-27

申请号：US14113760

申请日：2012-04-26

Applicant: Marc Holtwick ,  James Alexander Davies ,  Simon Lewis Bilton ,  David Moore ,  Steven Wimpenny ,  Christopher Nigel Langley

Inventor： Marc Holtwick ,  James Alexander Davies ,  Simon Lewis Bilton ,  David Moore ,  Steven Wimpenny ,  Christopher Nigel Langley

IPC: A61M5/00 ,  A61J1/14 ,  A61M5/19 ,  A61M5/24 ,  A61M5/34 ,  A61M5/50 ,  A61M5/31 ,  A61M5/20 ,  A61M5/178

CPC classification number: A61J1/1475 ,  A61M5/19 ,  A61M5/2066 ,  A61M5/24 ,  A61M5/2448 ,  A61M5/345 ,  A61M5/348 ,  A61M5/50 ,  A61M2005/1787 ,  A61M2005/2496 ,  A61M2005/3125 ,  A61M2005/3128 ,  A61M2205/502

Abstract: The invention is related to a manifold comprising at least two valve receptacles, further comprising a fluid groove arrangement comprising at least two fluid grooves, wherein a first fluid groove of the at least two fluid grooves has a starting point near a first valve receptacle of the at least two valve receptacles and an end point near a second valve receptacle of the at least two valve receptacles and wherein a second fluid groove of the at least two fluid grooves has a starting point near a second valve receptacle of the at least two valve receptacles. The invention is further related to an apparatus comprising a manifold of the aforementioned kind and further comprising an inner body of a dispense interface.

公开(公告)号：US09717864B2

公开(公告)日：2017-08-01

申请号：US14113535

申请日：2012-04-26

Applicant: James Alexander Davies ,  Simon Lewis Bilton ,  David Moore ,  Steven Wimpenny ,  Christopher Nigel Langley

Inventor： James Alexander Davies ,  Simon Lewis Bilton ,  David Moore ,  Steven Wimpenny ,  Christopher Nigel Langley

IPC: A61M5/00 ,  A61M5/50 ,  A61M5/34 ,  A61M5/24 ,  A61M5/28

CPC classification number: A61M5/50 ,  A61M5/2448 ,  A61M5/284 ,  A61M5/34 ,  A61M2205/273

Abstract: A dispense interface for use with a drug delivery device with an inner body and with a lockout element. The lockout element is coupled to the inner body movable from a receptive condition to a locked condition, wherein in the receptive condition the dispense interface is attachable to the drug delivery device. In the locked condition, the dispense interface is not-attachable to the drug delivery device. The lockout element is configured to move from the receptive condition to the locked condition when said dispense interface is attached to and detached from said drug delivery device.

公开(公告)号：US09238107B2

公开(公告)日：2016-01-19

申请号：US13322097

申请日：2010-06-01

Applicant: James Alexander Davies ,  Steven Wimpenny ,  Daniel Thomas De Sausmarez Lintell ,  Malcolm Stanley Boyd ,  Naceur Rekaya ,  Simon Lewis Bilton ,  John David Cross

Inventor： James Alexander Davies ,  Steven Wimpenny ,  Daniel Thomas De Sausmarez Lintell ,  Malcolm Stanley Boyd ,  Naceur Rekaya ,  Simon Lewis Bilton ,  John David Cross

IPC: A61M5/31 ,  A61M5/32 ,  A61M5/28 ,  A61M5/00 ,  A61M5/20 ,  A61M5/14 ,  A61J1/20 ,  A61M5/315 ,  A61M5/34 ,  A61M5/178

CPC classification number: A61M5/284 ,  A61J1/20 ,  A61J1/2089 ,  A61M5/1409 ,  A61M5/1413 ,  A61M5/204 ,  A61M5/2066 ,  A61M5/288 ,  A61M5/31525 ,  A61M5/326 ,  A61M5/3294 ,  A61M5/3297 ,  A61M5/347 ,  A61M2005/1787 ,  A61M2005/3142 ,  A61M2005/3247 ,  A61M2005/3267

Abstract: A medicated module attachable to a drug delivery device comprises a connecting body configured for attachment to the drug delivery device. A first needle is fixed within the connecting body and a movable needle hub is operatively coupled to the connecting body. A needle guard is operatively coupled to the connecting body and a biasing member is positioned between the connecting body and needle guard. A second needle is fixed within the needle hub. A first cavity within the connecting body defines a reservoir containing at least one dose of a medicament. The reservoir configured for fluid communication with the first and the second needle. The reservoir comprises a bypass configured to allow medicament from the drug delivery device to bypass the reservoir and exit the second needle.

Abstract translation: 可附接到药物递送装置的药物模块包括构造成附接到药物递送装置的连接体。 第一针固定在连接体内，并且可动针座可操作地联接到连接体。 针护罩可操作地联接到连接体，并且偏置构件定位在连接体和针护罩之间。 第二针固定在针座内。 连接体内的第一腔体限定含有至少一剂药物的储液器。 储存器被配置成与第一和第二针流体连通。 储存器包括旁路，其构造成允许来自药物输送装置的药物绕过储存器并离开第二针。

公开(公告)号：US09155838B2

公开(公告)日：2015-10-13

申请号：US13520692

申请日：2011-02-01

Applicant: Simon Lewis Bilton ,  Malcolm Stanley Boyd ,  James Alexander Davies ,  John David Cross ,  Aled Meredydd James ,  David Moore ,  Daniel Thomas De Sausmarez Lintell

Inventor： Simon Lewis Bilton ,  Malcolm Stanley Boyd ,  James Alexander Davies ,  John David Cross ,  Aled Meredydd James ,  David Moore ,  Daniel Thomas De Sausmarez Lintell

IPC: A61M5/24 ,  A61M5/315 ,  A61M5/32 ,  A61M5/28 ,  A61M5/31 ,  A61M5/34 ,  A61M5/178

CPC classification number: A61M5/2448 ,  A61M5/2466 ,  A61M5/284 ,  A61M5/288 ,  A61M5/3146 ,  A61M5/31525 ,  A61M5/31545 ,  A61M5/3155 ,  A61M5/326 ,  A61M5/3271 ,  A61M5/3294 ,  A61M5/3297 ,  A61M5/3298 ,  A61M5/347 ,  A61M2005/1787 ,  A61M2005/3247 ,  A61M2005/3267

Abstract: A medicated module (100) is attachable to a drug delivery device (102). The medicated module (100) includes a housing (104) having a proximal end and a distal end, the proximal end has a connector (110) configured for attachment to a drug delivery device (102). The distal end contains a shuttle (112). A first needle (114) is fixed in the housing (104) and a second needle (116) is fixed in the shuttle (112). The medicated module (100) also includes a reservoir (118) in the housing (104) comprising a medicament (12). Further, the medicated module (100) includes a guard assembly (122) positioned in the housing (104) and configured to move in an axial direction during application to an injection site. Preferably, the medicated module (100) is locked out after at least two injections of the medicament (105) contained in the drug delivery device (102).

Abstract translation: 药物模块（100）可附接到药物输送装置（102）。 所述药物模块（100）包括具有近端和远端的壳体（104），所述近端具有被配置为附接到药物输送装置（102）的连接器（110）。 远端包含梭子（112）。 第一针（114）固定在壳体（104）中，第二针（116）固定在梭子（112）中。 所述药物模块（100）还包括在所述壳体（104）中的包含药物（12）的储存器（118）。 此外，药物组件（100）包括定位在壳体（104）中的防护组件（122），并构造成在施加到注射部位期间沿轴向方向移动。 优选地，在药物输送装置（102）中包含的药物（105）至少两次注射之后，药物模块（100）被锁定。

公开(公告)号：US20140046267A1

公开(公告)日：2014-02-13

申请号：US14113760

申请日：2012-04-26

Applicant: Marc Holtwick ,  James Alexander Davies ,  Simon Lewis Bilton ,  David Moore ,  Steven Wimpenny ,  Christopher Nigel Langley

Inventor： Marc Holtwick ,  James Alexander Davies ,  Simon Lewis Bilton ,  David Moore ,  Steven Wimpenny ,  Christopher Nigel Langley

IPC: A61M5/00 ,  A61J1/14

CPC classification number: A61J1/1475 ,  A61M5/19 ,  A61M5/2066 ,  A61M5/24 ,  A61M5/2448 ,  A61M5/345 ,  A61M5/348 ,  A61M5/50 ,  A61M2005/1787 ,  A61M2005/2496 ,  A61M2005/3125 ,  A61M2005/3128 ,  A61M2205/502

Abstract: The invention is related to a manifold comprising at least two valve receptacles, further comprising a fluid groove arrangement comprising at least two fluid grooves, wherein a first fluid groove of the at least two fluid grooves has a starting point near a first valve receptacle of the at least two valve receptacles and an end point near a second valve receptacle of the at least two valve receptacles and wherein a second fluid groove of the at least two fluid grooves has a starting point near a second valve receptacle of the at least two valve receptacles. The invention is further related to an apparatus comprising a manifold of the aforementioned kind and further comprising an inner body of a dispense interface.

Abstract translation: 本发明涉及包括至少两个阀座的歧管，还包括流体槽布置，其包括至少两个流体槽，其中所述至少两个流体槽的第一流体槽具有靠近所述至少两个流体槽的第一阀座的起始点 至少两个阀座和至少两个阀座的第二阀座附近的端点，并且其中所述至少两个流体槽的第二流体槽具有靠近所述至少两个阀座的第二阀座的起始点 。 本发明还涉及一种包括上述类型的歧管的装置，还包括分配界面的内部主体。

公开(公告)号：US20140039390A1

公开(公告)日：2014-02-06

申请号：US14113396

申请日：2012-04-26

Applicant: Marc Holtwick ,  Ilona Eggert ,  James Alexander Davies ,  Simon Lewis Bilton ,  David Moore ,  Steven Wimpenny ,  Christopher Nigel Langley

Inventor： Marc Holtwick ,  Ilona Eggert ,  James Alexander Davies ,  Simon Lewis Bilton ,  David Moore ,  Steven Wimpenny ,  Christopher Nigel Langley

IPC: A61M5/50

CPC classification number: A61M5/50 ,  A61M5/19 ,  A61M5/31535 ,  A61M5/31538 ,  A61M5/34

Abstract: The invention is related to an apparatus comprising a dispense interface for use with a drug delivery device, the dispense interface comprising a lockout element being arranged at least partially between an outer body of the dispense interface and an inner body of the dispense interface and wherein the lockout element is configured to be removeably maintained in a first position, such that when the dispense interface is first attached and then removed from said drug delivery device, the lockout element moves into a second position, wherein the lockout element in the second position is configured to prevent said dispense interface from being reattached to a drug delivery device.

Abstract translation: 本发明涉及一种包括用于药物输送装置的分配界面的装置，所述分配界面包括至少部分地布置在分配界面的外部主体和分配界面的内部主体之间的锁定元件，并且其中， 闭锁元件被配置为可移除地保持在第一位置，使得当分配界面首先被附接并且然后从所述药物输送装置移除时，锁定元件移动到第二位置，其中配置在第二位置的锁定元件被配置 以防止所述分配界面重新附接到药物输送装置。

公开(公告)号：US20120283649A1

公开(公告)日：2012-11-08

申请号：US13395898

申请日：2010-09-29

Applicant: Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne Macdonald

Inventor： Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne Macdonald

IPC: A61M5/315

CPC classification number: A61M5/31535 ,  A61M5/24 ,  A61M5/31543 ,  A61M5/31555 ,  A61M5/3156 ,  A61M5/3158 ,  A61M5/31593 ,  A61M2005/2407

Abstract: A plunger and a lever are arranged in a body and provided with engaging elements engaging the lever with the plunger. The lever is disengageable from the plunger by a shift of the lever, thus enabling a movement of the plunger relatively to the body in the proximal direction.

Abstract translation: 柱塞和杠杆布置在主体中并且设置有与杠杆与柱塞接合的接合元件。 杠杆通过杠杆的移动而与柱塞脱离，从而使得柱塞能够在近端方向上相对于身体移动。

公开(公告)号：US20120283648A1

公开(公告)日：2012-11-08

申请号：US13496536

申请日：2010-09-29

Applicant: Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

Inventor： Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

IPC: A61M5/31

CPC classification number: A61M5/24 ,  A61M5/31541 ,  A61M5/31555 ,  A61M5/31558 ,  A61M5/31561 ,  A61M5/31575 ,  A61M5/31593 ,  A61M2005/2407 ,  A61M2005/2488 ,  A61M2005/3142

Abstract: A first output member is rotatable around an axis relatively to the body. A second output member is movable relatively to the body along the axis. The first output member and the second output member are rotationally coupled. A drive feature is provided to generate a rotation of the first output member. A part which is removable from and attachable to the body is provided so that the first output member is unidirectionally rotationally coupled with the drive feature when the part is attached to the body.

Abstract translation: 第一输出构件可绕相对于身体的轴线旋转。 第二输出构件可相对于主体沿轴线移动。 第一输出构件和第二输出构件被旋转地联接。 提供驱动特征以产生第一输出构件的旋转。 提供从主体可移除并可附接到本体的部分，使得当部件附接到主体时，第一输出部件与驱动部件单方向地旋转耦合。

公开(公告)号：US20120130346A1

公开(公告)日：2012-05-24

申请号：US13375994

申请日：2010-06-01

Applicant: James Alexander Davies ,  Steven Wimpenny ,  Daniel Thomas De Sausmarez Lintell ,  Malcolm Stanley Boyd ,  Naceur Rekaya ,  Simon Lewis Bilton ,  John David Cross ,  David Moore ,  Jay Graham ,  Ross Douglas MacArthur ,  Michael James David Heald ,  Christopher James Smith

Inventor： James Alexander Davies ,  Steven Wimpenny ,  Daniel Thomas De Sausmarez Lintell ,  Malcolm Stanley Boyd ,  Naceur Rekaya ,  Simon Lewis Bilton ,  John David Cross ,  David Moore ,  Jay Graham ,  Ross Douglas MacArthur ,  Michael James David Heald ,  Christopher James Smith

IPC: A61M5/31 ,  A61M5/32

CPC classification number: A61M5/2448 ,  A61M5/2466 ,  A61M5/31525 ,  A61M5/31556 ,  A61M5/32 ,  A61M5/3294 ,  A61M5/347 ,  A61M2005/1787 ,  A61M2206/20

Abstract: A medicated module (4) for an injection system to co-deliver at least two medicaments (1, 2) is disclosed where a primary delivery device (7) containing a primary medicament (1) accepts a medicated module (4) containing a single dose of a secondary medicament (2) and where both medicaments (1, 2) are delivered through a single hollow needle (3, 16, 21, 31).

Abstract translation: 公开了一种用于共同递送至少两种药物（1,2）的注射系统的药物模块（4），其中包含主药物（1）的主要递送装置（7）接受含有单一药物的药物模块（4） 二次药剂（2）的剂量，并且其中两种药物（1,2）通过单个中空针（3,16,21,31）递送。

公开(公告)号：US09884156B2

公开(公告)日：2018-02-06

申请号：US14113396

申请日：2012-04-26

Applicant: Marc Holtwick ,  Ilona Eggert ,  James Alexander Davies ,  Simon Lewis Bilton ,  David Moore ,  Steven Wimpenny ,  Christopher Nigel Langley

Inventor： Marc Holtwick ,  Ilona Eggert ,  James Alexander Davies ,  Simon Lewis Bilton ,  David Moore ,  Steven Wimpenny ,  Christopher Nigel Langley

IPC: A61M5/50 ,  A61M5/19 ,  A61M5/34 ,  A61M5/315

CPC classification number: A61M5/50 ,  A61M5/19 ,  A61M5/31535 ,  A61M5/31538 ,  A61M5/34

Abstract: The invention is related to an apparatus comprising a dispense interface for use with a drug delivery device, the dispense interface comprising a lockout element being arranged at least partially between an outer body of the dispense interface and an inner body of the dispense interface and wherein the lockout element is configured to be removeably maintained in a first position, such that when the dispense interface is first attached and then removed from said drug delivery device, the lockout element moves into a second position, wherein the lockout element in the second position is configured to prevent said dispense interface from being reattached to a drug delivery device.