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公开(公告)号：US20130243728A9
公开(公告)日：2013-09-19
申请号：US13510172
申请日：2010-11-18
CPC分类号： C07K14/4703 , C07K14/515
摘要： The invention relates to a recombinant microorganism comprising a transgene encoding angiogenin and optionally follistatin, a food product, beverage product or animal feed produced from or comprising said microorganism and uses thereof.
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公开(公告)号：US20130039889A1
公开(公告)日：2013-02-14
申请号：US13510172
申请日：2011-11-18
CPC分类号： C07K14/4703 , C07K14/515
摘要： The invention relates to a recombinant microorganism comprising a transgene encoding angiogenin and optionally follistatin, a food product, beverage product or animal feed produced from or comprising said microorganism and uses thereof.
摘要翻译： 本发明涉及包含编码血管生成素和任选的卵泡抑素的转基因的重组微生物，由所述微生物产生或包含所述微生物的食品，饮料产品或动物饲料及其用途。
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公开(公告)号：US20120328591A1
公开(公告)日：2012-12-27
申请号：US13510167
申请日：2010-11-18
CPC分类号： C07K14/515 , A61K38/00 , A61K47/64
摘要： The invention provides a method of improving the oral delivery of a therapeutic agent, comprising the step of linking the therapeutic agent to a carrier protein comprising angiogenin, fusion proteins or conjugates comprising angiogenin and a therapeutic agent and their use in medicine.
摘要翻译： 本发明提供了一种改善治疗剂的口服递送的方法，包括将治疗剂与包含血管生成素，融合蛋白或包含血管生成素和治疗剂的缀合物的载体蛋白质连接的方法及其在药物中的用途。
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公开(公告)号：US08871266B2
公开(公告)日：2014-10-28
申请号：US10573784
申请日：2004-03-30
IPC分类号： C12N1/00 , C12N1/04 , C12N1/12 , C12N11/00 , C12N11/16 , C12P1/00 , C12P1/04 , C12P7/00 , C12P19/00 , C12P39/00 , A61K36/064 , A61K35/74 , A61K47/42 , A61K47/26 , A61K47/44 , A61K9/19
CPC分类号： A61K47/26 , A61K9/19 , A61K35/741 , A61K35/744 , A61K35/745 , A61K35/747 , A61K36/064 , A61K47/42 , A61K47/44 , Y10S435/822 , Y10S435/853 , Y10S435/885 , Y10S435/886
摘要： Probiotic microorganisms are micro encapsulated by dispersing the probiotic microorganism in an aqueous suspension of a film forming protein and a carbohydrate; in an oil in water emulsion of a film forming protein and a carbohydrate and a fat; or in an oil which is subsequently dispersed in a film forming protein and a carbohydrate. The emulsion or suspension may be dried to form a powder. The probiotic may be dispersed in oil and then emulsified with the aqueous suspension and then dried to produce an encapsulated oil be dried to produce a powder. Oil suspended probiotics may be preferred where the probiotic is water sensitive. The preferred protein is casein or whey protein and the carbohydrate may be a resistant starch or a saccharide with a reducing sugar group. Where the probiotic is oxygen sensitive the protein carbohydrate is heated to create Maillard reaction products in the encapsulating film.
摘要翻译： 益生菌微生物通过将益生菌微生物分散在成膜蛋白质和碳水化合物的水悬浮液中来微囊化; 在成膜蛋白质和碳水化合物和脂肪的水包油乳液中; 或随后分散在成膜蛋白质和碳水化合物中的油中。 可以将乳液或悬浮液干燥以形成粉末。 益生菌可以分散在油中，然后用水悬浮液乳化，然后干燥以产生待干燥的包封的油以产生粉末。 在益生菌对水敏感的地方，优选油悬浮的益生菌。 优选的蛋白质是酪蛋白或乳清蛋白，碳水化合物可以是抗性淀粉或具有还原糖基团的糖。 当益生菌对氧敏感时，蛋白质碳水化合物被加热以在封装膜中产生美拉德反应产物。
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公开(公告)号：US20070122397A1
公开(公告)日：2007-05-31
申请号：US10573784
申请日：2004-03-30
IPC分类号： A61K35/74
CPC分类号： A61K47/26 , A61K9/19 , A61K35/741 , A61K35/744 , A61K35/745 , A61K35/747 , A61K36/064 , A61K47/42 , A61K47/44 , Y10S435/822 , Y10S435/853 , Y10S435/885 , Y10S435/886
摘要： Probiotic microorganisms are micro encapsulated by dispersing the probiotic microorganism in an aqueous suspension of a film forming protein and a carbohydrate; in an oil in water emulsion of a film forming protein and a carbohydrate and a fat; or in an oil which is subsequently dispersed in a film forming protein and a carbohydrate. The emulsion or suspension may be dried to form a powder. The probiotic may be dispersed in oil and then emulsified with the aqueous suspension and then dried to produce an encapsulated oil be dried to produce a powder. Oil suspended probiotics may be preferred where the probiotic is water sensitive. The preferred protein is casein or whey protein and the carbohydrate may be a resistant starch or a saccharide with a reducing sugar group. Where the probiotic is oxygen sensitive the protein carbohydrate is heated to create Maillard reaction products in the encapsulating film.
摘要翻译： 益生菌微生物通过将益生菌微生物分散在成膜蛋白质和碳水化合物的水悬浮液中来微囊化; 在成膜蛋白质和碳水化合物和脂肪的水包油乳液中; 或随后分散在成膜蛋白质和碳水化合物中的油中。 可以将乳液或悬浮液干燥以形成粉末。 益生菌可以分散在油中，然后用水悬浮液乳化，然后干燥以产生待干燥的包封的油以产生粉末。 在益生菌对水敏感的地方，优选油悬浮的益生菌。 优选的蛋白质是酪蛋白或乳清蛋白，碳水化合物可以是抗性淀粉或具有还原糖基团的糖。 当益生菌对氧敏感时，蛋白质碳水化合物被加热以在封装膜中产生美拉德反应产物。
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