公开(公告)号：US08383678B2

公开(公告)日：2013-02-26

申请号：US12984994

申请日：2011-01-05

申请人： Jean-Pierre Sachetto ,  Roly Bufton ,  Thomas Buser

发明人： Jean-Pierre Sachetto ,  Roly Bufton ,  Thomas Buser

IPC分类号： A61K31/202 ,  A61K9/48

CPC分类号： A61K31/202 ,  A61K9/4825 ,  A61K9/4891 ,  A61K31/20 ,  A61K31/201 ,  A61K31/23

摘要： A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterized in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.

摘要翻译： 包含游离酸形式的至少一种ω-3多不饱和脂肪酸或其药理学上可接受的衍生物的药物制剂包含在软明胶胶囊中，其特征在于所述胶囊包括通过提取方法提取的明胶，所述提取方法包括对胶原进行酸预处理 资源。 本发明相对于含有相同制剂但含有通过包括碱预处理胶原源的提取方法提取的明胶的软明胶胶囊的一个优点是本发明不会随着时间的推移显着硬化，因此具有更长的保质期 。

公开(公告)号：US07960370B2

公开(公告)日：2011-06-14

申请号：US10587201

申请日：2005-02-07

申请人： Jean-Pierre Sachetto ,  Roly Bufton ,  Thomas Buser

发明人： Jean-Pierre Sachetto ,  Roly Bufton ,  Thomas Buser

IPC分类号： A61K31/33 ,  A61K31/194

CPC分类号： A61K31/202 ,  A61K9/4825 ,  A61K9/4891 ,  A61K31/20 ,  A61K31/201 ,  A61K31/23

摘要： A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterized in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.

摘要翻译： 包含游离酸形式的至少一种ω-3多不饱和脂肪酸或其药理学上可接受的衍生物的药物制剂包含在软明胶胶囊中，其特征在于所述胶囊包括通过提取方法提取的明胶，所述提取方法包括对胶原进行酸预处理 资源。 本发明相对于含有相同制剂但含有通过包括碱预处理胶原源的提取方法提取的明胶的软明胶胶囊的一个优点是本发明不会随着时间的推移显着硬化，因此具有更长的保质期 。

公开(公告)号：US20110097394A1

公开(公告)日：2011-04-28

申请号：US12984994

申请日：2011-01-05

申请人： Jean-Pierre Sachetto ,  Roly Bufton ,  Thomas Buser

发明人： Jean-Pierre Sachetto ,  Roly Bufton ,  Thomas Buser

IPC分类号： A61K31/202 ,  A61K9/48 ,  A61P29/00 ,  A61P3/06 ,  A61P11/06 ,  A61P35/00 ,  A61P1/04 ,  A61P17/06 ,  A61P19/02

CPC分类号： A61K31/202 ,  A61K9/4825 ,  A61K9/4891 ,  A61K31/20 ,  A61K31/201 ,  A61K31/23

摘要： A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.

摘要翻译： 包含游离酸形式的至少一种ω-3多不饱和脂肪酸或其药理学上可接受的衍生物的药物制剂包含在软明胶胶囊中，其特征在于所述胶囊包括通过提取方法提取的明胶，所述提取方法包括对胶原进行酸预处理 资源。 本发明相对于含有相同制剂但含有通过包括碱预处理胶原源的提取方法提取的明胶的软明胶胶囊的一个优点是本发明不会随着时间的推移显着硬化，因此具有更长的保质期 。

公开(公告)号：US20070269507A1

公开(公告)日：2007-11-22

申请号：US10587201

申请日：2005-02-07

申请人： Jean-Pierre Sachetto ,  Roly Bufton ,  Thomas Buser

发明人： Jean-Pierre Sachetto ,  Roly Bufton ,  Thomas Buser

IPC分类号： A61K31/202 ,  A61K9/64 ,  A61P29/00 ,  A61P3/00

CPC分类号： A61K31/202 ,  A61K9/4825 ,  A61K9/4891 ,  A61K31/20 ,  A61K31/201 ,  A61K31/23

摘要： A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.

摘要翻译： 包含游离酸形式的至少一种ω-3多不饱和脂肪酸或其药理学上可接受的衍生物的药物制剂包含在软明胶胶囊中，其特征在于所述胶囊包括通过提取方法提取的明胶，所述提取方法包括对胶原进行酸预处理 资源。 本发明相对于含有相同制剂但含有通过包括碱预处理胶原源的提取方法提取的明胶的软明胶胶囊的一个优点是本发明不会随着时间的推移显着硬化，因此具有更长的保质期 。

公开(公告)号：US20140228437A1

公开(公告)日：2014-08-14

申请号：US14258523

申请日：2014-04-22

申请人： Jean-Pierre SACHETTO ,  Roly BUFTON ,  Thomas BUSER

发明人： Jean-Pierre SACHETTO ,  Roly BUFTON ,  Thomas BUSER

IPC分类号： A61K31/202 ,  A61K9/48

CPC分类号： A61K31/202 ,  A61K9/4825 ,  A61K9/4891 ,  A61K31/20 ,  A61K31/201 ,  A61K31/23

摘要： A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.

摘要翻译： 包含游离酸形式的至少一种ω-3多不饱和脂肪酸或其药理学上可接受的衍生物的药物制剂包含在软明胶胶囊中，其特征在于所述胶囊包括通过提取方法提取的明胶，所述提取方法包括对胶原进行酸预处理 资源。 本发明相对于含有相同制剂但含有通过包括碱预处理胶原源的提取方法提取的明胶的软明胶胶囊的一个优点是本发明不会随着时间的推移显着硬化，因此具有更长的保质期 。