公开(公告)号：US5702823A

公开(公告)日：1997-12-30

申请号：US728823

申请日：1996-10-10

Applicant: Lloyd Forrestal ,  Marc Voorhees ,  Yung-Ming Chen ,  Richard A. Edrich

Inventor： Lloyd Forrestal ,  Marc Voorhees ,  Yung-Ming Chen ,  Richard A. Edrich

IPC: A61L33/00 ,  A61L27/34 ,  A61L31/10 ,  A61L33/06 ,  B01D67/00 ,  C08G77/42 ,  C08J7/00 ,  C09D183/10 ,  B32B15/08

CPC classification number: B01D67/0088 ,  A61L27/34 ,  A61L31/10 ,  A61L33/068 ,  C09D183/10 ,  Y10T428/249978 ,  Y10T428/24998 ,  Y10T428/249992 ,  Y10T428/31663 ,  Y10T428/31667 ,  Y10T428/31681 ,  Y10T428/31786 ,  Y10T428/31797

Abstract: The biocompatibility of polymeric and metallic articles used in contact with blood can be substantially improved by coating the articles as described. The coating materials are triblock copolymers of the polylactone-polysiloxane-polylactone type. Optimum biocompatibility is provided by a coating of optimum surface concentration. Porous membranes can be coated as described, providing improved biocompatibility of blood oxygenators, hemodialyzers and the like.