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公开(公告)号：US20230118351A1
公开(公告)日：2023-04-20
申请号：US16978674
申请日：2020-02-20
发明人： Tingfeng CAO , Fang FAN , Shengcan ZOU , Guojunnan FENG , Jinli LIU , Xiu LU , Zengliang ZHANG
摘要： This application belongs to the field of biotechnology and discloses a method for producing a clam active peptide. The method for producing a clam active peptide comprises cleaning fresh clam meat with water, adding water and homogenizing with a colloid mill to prepare a clam meat slurry; adding water and complex protease for enzymolysis of the clam meat slurry, and heating to inactivate enzyme after the enzymolysis; centrifuging to collect an enzymatic hydrolyzate, capturing the enzymatic hydrolyzate having a molecular weight of lower than 2 KDa through microfiltration-ultrafiltration-nanofiltration membrane filtration, and drying to obtain the clam active peptide. The present disclosure produces a clam active peptide having pure color, outstanding taste, and blood pressure lowering function which is easily absorbed by human body using fresh clam meat as raw material, adopting a complex enzyme-membrane coupling technology through processing techniques such as enzymolysis, membrane separation purification and drying.
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公开(公告)号：US20210301314A1
公开(公告)日：2021-09-30
申请号：US17180727
申请日：2021-02-20
发明人： Shengcan Zou , Changwei Wang , Yanmei Wang , Shanglong Wang , Tingfeng Cao , Bafang Li
摘要： A preparation method and an application of sea cucumber protein peptides are disclosed. The disclosure develops a preparation method of sea cucumber protein peptides with simple operation and excellent product quality by optimizing raw materials and enzymolysis extraction process of sea cucumber protein peptides. On the one hand, the problem that the deodorization and decolorization effect of the sea cucumber peptide hydrolysate of the prior art is not obvious is solved. On the other hand, the obtained sea cucumber protein peptides can be processed into nutritional supplements and used as raw materials for preparing health care products or cosmetics for enhancing immunity, relieving physical fatigue, resisting oxidation and aging, which has good development and utilization potential.
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公开(公告)号：US20220241362A1
公开(公告)日：2022-08-04
申请号：US17213340
申请日：2021-03-26
发明人： Shengcan Zou , Zengliang Zhang , Min Wang , Zhuqing Liu , Sai Lu , Li Li , Shanglong Wang
IPC分类号： A61K36/296 , A61K38/01 , A61K31/737 , A61K31/7008 , A61K36/537 , A61K36/8945
摘要： A multi-efficacy traditional Chinese medicine compound composition and application thereof in pharmaceutical preparations are disclosed. The traditional Chinese medicine extracts are combined with the glucosamine, the collagen and the chondroitin sulfate, so that the multi-efficacy traditional Chinese medicine compound composition is prepared. The traditional Chinese medicine compound composition starts from improving the health of bone and joint and accompanying cardiovascular disease, selects the medicinal materials, and optimizes the extraction process of the traditional Chinese medicine for the diseases dominated by degenerative osteoarthritis. The disclosure has the efficacious of improving the symptoms of degenerative osteoarthritis, reducing blood pressure, improving the symptoms with osteoporosis, improving the symptoms with cardiovascular disease, improving the symptoms with urinary system disease, etc. It also has the characteristics of less dosage, significant curative effect and various functions, which is suitable for market promotion and application.
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公开(公告)号：US20210109068A1
公开(公告)日：2021-04-15
申请号：US17094840
申请日：2020-11-11
发明人： Shengcan Zou , Jiancheng Zong , Wenyu Li , Lei Zong , Zengliang Zhang , Shanglong Wang
IPC分类号： G01N30/86 , B01J20/286 , B01J20/10 , A61K36/185 , A61K36/65 , A61K36/744 , A61K36/48 , G01N30/06 , G01N30/60
摘要： The present invention discloses a fingerprint detection method for an antidepressant drug, which adopts liquid chromatography to characterize pharmacological active ingredients of the antidepressant drug composed of Hypericum perforatum L., Paeonia lactiflora Pall, Gardenia jasminoides Ellis, Albizia julibrissin Durazz, and Moutan Cortex, provides an effective detection method, and realizes the quality control of traditional Chinese medicine compositions. The fingerprint detection method provided by the present invention has the advantages of high repeatability and high stability.
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公开(公告)号：US11975052B2
公开(公告)日：2024-05-07
申请号：US17156534
申请日：2021-01-23
发明人： Shengcan Zou , Zengliang Zhang , Jiancheng Zong , Wenyu Li , Xin Li , Li Li , Shanglong Wang , Lei Zong
IPC分类号： A61K38/39 , A23J3/34 , A23L29/281 , A23L33/00 , A23L33/105 , A23L33/155 , A23L33/16 , A23L33/17 , A61K31/122 , A61K31/593 , A61K33/06 , A61K36/126 , A61K36/39 , A61K36/46 , A61P19/00
CPC分类号： A61K38/39 , A23L29/284 , A23L33/105 , A23L33/155 , A23L33/16 , A23L33/17 , A23L33/40 , A61K31/122 , A61K31/593 , A61K33/06 , A61K36/126 , A61K36/39 , A61K36/46 , A61P19/00 , A23J3/342 , A23V2002/00 , A23V2250/5422 , A61K2236/31 , A61K2236/333 , A61K2236/37 , A61K2236/51 , A61K2236/53
摘要： A compound composition for improving bone health and preparation and application thereof are provided. The compound composition is prepared by combining a traditional Chinese medicine extract with chicken cartilage collagen, magnesium, vitamin K2 and vitamin D3. The compound composition overcomes the food safety risk of the existing osteoporosis preventive drugs by adding the traditional Chinese medicine extract for improving osteoporosis and promoting bone health. And the compound composition disclosed can be used as a dietary supplement or health food raw material for preventing or treating osteoporosis. Therefore, the compound composition disclosed is suitable for promotion and application.
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公开(公告)号：US20220152162A1
公开(公告)日：2022-05-19
申请号：US17156534
申请日：2021-01-23
发明人： Shengcan Zou , Zengliang Zhang , Jiancheng Zong , Wenyu Li , Xin Li , Li Li , Shanglong Wang , Lei Zong
IPC分类号： A61K38/39 , A61K33/06 , A61K31/122 , A61K31/593 , A61K36/46 , A61K36/126 , A61K36/39 , A61P19/00 , A23L33/00 , A23L33/17 , A23L33/16 , A23L33/155 , A23L33/105
摘要： A compound composition for improving bone health and preparation and application thereof are provided. The compound composition is prepared by combining a traditional Chinese medicine extract with chicken cartilage collagen, magnesium, vitamin K2 and vitamin D3. The compound composition overcomes the food safety risk of the existing osteoporosis preventive drugs by adding the traditional Chinese medicine extract for improving osteoporosis and promoting bone health. And the compound composition disclosed can be used as a dietary supplement or health food raw material for preventing or treating osteoporosis. Therefore, the compound composition disclosed is suitable for promotion and application.
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公开(公告)号：US11642388B2
公开(公告)日：2023-05-09
申请号：US17105628
申请日：2020-11-26
发明人： Shengcan Zou , Jiancheng Zong , Wenyu Li , Lei Zong , Zengliang Zhang , Shanglong Wang
IPC分类号： A61K36/744 , A61K36/185 , A61K36/65 , A61P25/24 , A61K36/48
CPC分类号： A61K36/744 , A61K36/185 , A61K36/48 , A61K36/65 , A61P25/24 , A61K2236/31 , A61K2236/333 , A61K2236/39
摘要： An antidepressant compound preparation and a preparation method for same were disclosed, The antidepressant includes the following raw materials of Hypericum perforatum L., Paeonia lactiflora Pall., Gardenia jasminoides Ellis, Albizia julibrissin Durazz. and Moutan cortex. The raw materials are weighed in proportion to obtain extracts respectively, and the extracts are mixed to prepare a compound preparation. The compound preparation prepared by the present invention has the advantages of simple preparation, safety, low toxic and side effects, no dependence, etc., and can effectively alleviate depression mood.
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公开(公告)号：US20220175865A1
公开(公告)日：2022-06-09
申请号：US17315224
申请日：2021-05-07
发明人： Shengcan Zou , Jiancheng Zong , Wenyu Li , Xin Li , Lei Zong , Zengliang Zhang , Shanglong Wang
IPC分类号： A61K36/744 , A61K36/65 , A61K36/48 , A61K9/00 , A61P25/22
摘要： A traditional Chinese medicine compound composition with anti-anxiety effect and its preparation method and application are disclosed. The traditional Chinese medicine compound composition with anti-anxiety effect is prepared by compounding the Paeoniae Radix Alba extract, the Gardeniae Fructus extract, the Albiziae Flos extract and the Moutan Cortex extract. The traditional Chinese medicine compound composition has no toxic side effects and has remarkable treatment effect, and can be used as a dietary supplement or a health-care food ingredient to prevent and treat anxiety disorder, and promote mental health. It can be seen that the traditional Chinese medicine compound composition is suitable for promotion and application.
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公开(公告)号：US20220160807A1
公开(公告)日：2022-05-26
申请号：US17105628
申请日：2020-11-26
发明人： Shengcan Zou , Jiancheng Zong , Wenyu Li , Lei Zong , Zengliang Zhang , Shanglong Wang
IPC分类号： A61K36/744 , A61K36/185 , A61K36/65 , A61K36/48 , A61P25/24
摘要： An antidepressant compound preparation and a preparation method for same were disclosed, The antidepressant includes the following raw materials of Hypericum perforatum L., Paeonia lactiflora Pall., Gardenia jasminoides Ellis, Albizia julibrissin Durazz. and Moutan Cortex. The raw materials are weighed in proportion to obtain extracts respectively, and the extracts are mixed to prepare a compound preparation. The compound preparation prepared by the present invention has the advantages of simple preparation, safety, low toxic and side effects, no dependence, etc., and can effectively alleviate depression mood.
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公开(公告)号：US20220087926A1
公开(公告)日：2022-03-24
申请号：US17207740
申请日：2021-03-22
发明人： Shengcan Zou , Zengliang Zhang , Min Wang , Sai Lu , Zhuqing Liu , Jiancheng Zong , Shanglong Wang
IPC分类号： A61K8/9794 , A61K8/9789 , A61K8/9728 , A61Q19/08 , A23L33/105 , A61K36/076 , A61K36/8965 , A61K36/258 , A61K36/64 , A61K36/738 , A61K36/537 , A61K9/48 , A23L33/00
摘要： A compound composition with anti-oxidation and anti-aging effects and preparation method and application thereof we disclosed. 5-8 kinds of traditional Chinese medicine extracts from separate extraction of Panax ginseng C. A. Meyer, Poria, Rehmannia glutinosa, Cistanche deserticola Ma, Salviae Miltiorrhizae, Codonopsis Radix, Persicae Semen and Ophiopogon japonicus (Linn.f.) Ker-Gawl. are compounded with chitooligosaccharide to prepare the compound composition with anti-oxidation and anti-aging effects. The compound composition has no toxic side effects, is easy to be absorbed, and can be used for delaying aging, repairing DNA damage and anti-oxidation damage, and can also reduce the risk of geriatric diseases. Moreover, the compound composition can be used as a raw material of dietary supplement or health food to improve telomerase content and delay aging. Therefore, the compound composition is suitable for promotion and application.
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