公开(公告)号：US20090036305A1

公开(公告)日：2009-02-05

申请号：US11919588

申请日：2006-05-10

Applicant: Markus Gewehr ,  Jochen Dietz ,  Thomas Grote ,  Wassilios Gremmenos ,  Udo Hunger ,  Bernd Muller ,  Frank Schieweck ,  Anja Schwogler ,  Jan Klaas Lohmann ,  Joachim Rheinheimer ,  Jens Renner ,  Peter Schafer

Inventor： Markus Gewehr ,  Jochen Dietz ,  Thomas Grote ,  Wassilios Gremmenos ,  Udo Hunger ,  Bernd Muller ,  Frank Schieweck ,  Anja Schwogler ,  Jan Klaas Lohmann ,  Joachim Rheinheimer ,  Jens Renner ,  Peter Schafer

IPC: A01N43/56 ,  C07D231/14 ,  A01P3/00

CPC classification number: A01N43/56 ,  C07D231/14

Abstract: The present invention relates to pyrazolecarboxamides of the formula I in which the variables are as defined below: X is trifluoromethyl; R1 is F, Cl, Br, C1-C4-alkyl or C1-C4-haloalkyl; R2 is hydrogen, halogen or C1-C4-alkyl; R3 is hydrogen, C1-C4-alkyl, C1-C4-haloalkyl, C2-C4-alkenyl, C2-C4-alkynyl or C3-C6-cycloalkyl; W is O or S; with the proviso that, if R3 is hydrogen and W is oxygen, a) R1 and R2 are not simultaneously methyl and F, respectively; b) R1 and R2 are not simultaneously trifluoromethyl and hydrogen or fluorine, respectively. to processes for preparing these compounds, to seeds and compositions comprising them and to methods for controlling harmful fungi.

Abstract translation: 本发明涉及式I的吡唑酰胺，其中变量如下所定义：X是三氟甲基; R1是F，Cl，Br，C1-C4-烷基或C1-C4卤代烷基; R2是氢，卤素或C1-C4-烷基; R 3是氢，C 1 -C 4 - 烷基，C 1 -C 4卤代烷基，C 2 -C 4 - 烯基，C 2 -C 4 - 炔基或C 3 -C 6 - 环烷基; W为O或S; 条件是，如果R3是氢并且W是氧，则a）R1和R2分别不同时为甲基和F; b）R1和R2分别不同时为三氟甲基和氢或氟。 制备这些化合物的方法，包括它们的种子和组合物以及用于控制有害真菌的方法。

公开(公告)号：US20080314889A1

公开(公告)日：2008-12-25

申请号：US12214657

申请日：2008-06-20

Applicant: Martin Blanc ,  Peter Schafer ,  Gerd Brauchle

Inventor： Martin Blanc ,  Peter Schafer ,  Gerd Brauchle

IPC: F23Q13/00 ,  G05F5/00

CPC classification number: F02P19/02

Abstract: The description discloses a glow plug system for a Diesel engine of a motor vehicle having a glow plug (RG1, RG2) which comprises a positive terminal for connecting a supply voltage (U1) and a ground terminal for connecting to a ground potential (GND), a controlling device (1) for controlling the electric power supplied to the glow plug (RG1, RG2) in operation, whereby the controlling device (1) comprises a measurement input (ADC1) and a ground input (ADC2) in order to determine, in operation, a measured value of the supply voltage (U1) in relation to a reference potential (GND′) applied to the ground input (ADC2). The controlling device (1) has a test input (ADC3) which, in operation, is connected to a test voltage source via a first resistor (R1) and to the positive terminal of the glow plug (RG1, RG2) via a second resistor (R2), whereby the controlling device (1), in operation, determines a difference of the electric potential of the test input (ADC3) and the electric potential (GND′) of the ground input (ADC2), determines a deviation of the difference of these potentials from a reference value and, if this deviation is unequal to zero, uses the deviation to correct the measured value of the supply voltage (U1) and uses the corrected value of the supply voltage (U1) as for controlling the power. Furthermore, the description discloses a controlling device for a glow plug system of this type and a method for controlling the power of a glow plug.

Abstract translation: 该说明书公开了一种用于具有电热塞（RG1，RG2）的机动车辆的柴油发动机的电热塞系统，其包括用于连接电源电压（U1）的正极端子和用于连接到地电位（GND）的接地端子， 控制装置（1），用于控制在运行中提供给预热塞（RG1，RG2）的电力，由此控制装置（1）包括测量输入（ADC1）和接地输入（ADC2），以便确定 在操作中，相对于施加到接地输入（ADC2）的基准电位（GND'）的电源电压（U1）的测量值。 控制装置（1）具有测试输入（ADC3），其在操作中经由第一电阻器（R1）连接到测试电压源，并经由第二电阻器连接到电热塞（RG1，RG2）的正极端子 （R2），由此，操作中的控制装置（1）确定测试输入（ADC3）的电位差和接地输入（ADC2）的电位（GND'）之间的差异，确定 这些电位与参考值的差异，如果该偏差不等于零，则使用该偏差来校正电源电压（U1）的测量值，并使用电源电压（U1）的校正值作为控制功率 。 此外，该说明书公开了这种类型的电热塞系统的控制装置和用于控制电热塞的功率的方法。

公开(公告)号：US20080262000A1

公开(公告)日：2008-10-23

申请号：US11884412

申请日：2006-02-14

Applicant: Peter Schafer ,  Udo Hunger ,  Maria Scherer ,  Harald Kohle ,  Helmut Schiffer ,  Thomas Grote ,  Jochen Dietz ,  Wassilios Grammenos ,  Jan Klaas Lohmann ,  Bernd Muller ,  Joachim Rheinheimer ,  Frank Schieweck ,  Anja Schwogler

Inventor： Peter Schafer ,  Udo Hunger ,  Maria Scherer ,  Harald Kohle ,  Helmut Schiffer ,  Thomas Grote ,  Jochen Dietz ,  Wassilios Grammenos ,  Jan Klaas Lohmann ,  Bernd Muller ,  Joachim Rheinheimer ,  Frank Schieweck ,  Anja Schwogler

IPC: A01N43/90 ,  C07D487/04 ,  A01P3/00

CPC classification number: C07D487/04

Abstract: 5-Alkoxyalkyl-6-alkyl-7-aminoazolopyrimidines of the formula I in which the substituents are defined as follows: R1 is alkyl, cycloalkyl, alkenyl, alkynyl, alkoxyalkyl, cyanoalkyl, and benzyloxyalkyl, where the groups in the aliphatic or aromatic moiety may be unsubstituted or may have substitution by from one to three groups Ra: Ra is halogen, cyano, nitro, hydroxy, cycloalkyl, alkoxy, alkylthio, and NRARB; RA, RB are hydrogen and alkyl; R2 is alkoxyalkyl, phenoxyalkyl, alkylthioalkyl, and phenylthioalkyl, which groups may have no substitution or may have substitution according to the description; R3 is hydrogen and alkyl; A is N and C—RA; processes for preparation of these compounds, compositions comprising them, and their use for controlling phytopathogenic harmful fungi.

Abstract translation: 式I的5-烷氧基烷基-6-烷基-7-氨基偶氮嘧啶，其中取代基定义如下：R 1是烷基，环烷基，烯基，炔基，烷氧基烷基，氰基烷基和苄氧基烷基，其中 脂族或芳族部分中的基团可以是未取代的或可以具有一至三个基团的取代基：R a是卤素，氰基，硝基，羟基，环烷基 ，烷氧基，烷硫基和NR A R B， R A，B B是氢和烷基; R 2是烷氧基烷基，苯氧基烷基，烷硫基烷基和苯硫基烷基，该基团可以不具有取代基或可以根据描述进行取代; R 3是氢和烷基; A是N和C-R A; 制备这些化合物的方法，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。

公开(公告)号：US20080248952A1

公开(公告)日：2008-10-09

申请号：US11631004

申请日：2005-07-06

Applicant: Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Udo Hunger ,  Bernd Muller ,  Matthias Niedenbruck ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Oliver Wagner ,  Barbara Nave ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

Inventor： Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Udo Hunger ,  Bernd Muller ,  Matthias Niedenbruck ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Oliver Wagner ,  Barbara Nave ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC: C07D487/04 ,  A01N43/90 ,  A01N25/00

CPC classification number: A01N43/90 ,  C07D487/04

Abstract: Substituted triazolopyrimidines of the formula I in which the substituents are as defined below: R1 is alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, cycloalkenyl, halocycloalkenyl, alkynyl, haloalkynyl or phenyl, naphthyl, or a five- or six-membered saturated, partially unsaturated or aromatic heterocycle comprising one to four heteroatoms from the group consisting of O, N and S, R2 is hydrogen or a group R1, R1 and R2 together with the nitrogen atom, to which they are attached, may also form a five- or six-membered heterocyclyl or heteroaryl which is attached via N and which may comprise one to three further heteroatoms from the groups consisting of O, N and S as ring member and/or may be substituted according to the description; L is fluorine, chlorine or methyl; X is cyano, C1-C4-alkyl, C1-C4-alkoxy or C1-C2-haloalkoxy, where X is not methyl if R1 and R2 together are n-pentylene or 3-methyl-n-pentylene and L is fluorine, or R1 and R2 together are 3-methyl-n-pentylene and L is chlorine; processes and intermediates for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi.

Abstract translation: 取代基如下定义：式I的取代三唑并嘧啶：R 1是烷基，卤代烷基，环烷基，卤代环烷基，烯基，卤代烯基，环烯基，卤代环烯基，炔基， 包含一至四个由O，N和S组成的组的杂原子的五或六元饱和的部分不饱和或芳族杂环，R 2是氢或基团R 1， R 1，R 2和R 2与它们所连接的氮原子一起也可以形成五元或六元杂环基或杂芳基，它们是 通过N连接并且其可以包含一个至三个由O，N和S组成的基团的另外的杂原子作为环成员和/或可以根据描述被取代; L是氟，氯或甲基; X是氰基，C 1 -C 4 - 烷基，C 1 -C 4 - 烷氧基或C 1 -C 4 - 如果R 1和R 2一起都是正 - 亚戊基，其中X不是甲基，其中X不是甲基 或3-甲基 - 正戊烯，L是氟，R 1和R 2一起是3-甲基 - 正戊烯，L是氯; 制备这些化合物的方法和中间体，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。

公开(公告)号：US20080227795A1

公开(公告)日：2008-09-18

申请号：US10585992

申请日：2005-01-15

Applicant: Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Oliver Wagner ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

Inventor： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Oliver Wagner ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC: A01N43/90 ,  C07D487/04 ,  A01P3/00

CPC classification number: C07D487/04 ,  A01N43/90

Abstract: The invention relates to substituted triazolopyrimidines of formula (I), with the substituents as follows: R1, R2=H, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, cycloalkenyl, halocycloalkenyl, alkinyl, haloalkinyl, phenyl, naphthyl, or a five- or six-membered saturated, partially unsaturated or aromatic heterocycle, comprising one to four heteroatoms of the group O, N or S, R1 and R2 can, together with the nitrogen atom to which it is attached, form a five- or six-membered heterocycle or heteroaryl, bonded via N and containing one to three further heteroatoms from the group O, N and S as ring members, substituted as per the description, L1=fluorine, chlorine or bromine, L2=H, alkyl or alkoxy and X=halogen, cyano, alkyl, haloalkyl, alkoxy or haloalkoxy. The invention further relates to methods and intermediates for production of said compounds, agents comprising the same and use thereof for controlling fungal pests harmful to plants.

Abstract translation: 本发明涉及式（I）的取代三唑并嘧啶，其取代基如下：R 1，R 2 = H，烷基，卤代烷基，环烷基，卤代环烷基，烯基， 卤代烯基，环烯基，卤代环烯基，炔基，卤代炔基，苯基，萘基或五元或六元饱和的部分不饱和或芳族杂环，其包含一至四个O，N或S的杂原子， / SUP>和R 2可以与其所连接的氮原子一起形成五元或六元杂环或杂芳基，其通过N键合并含有一至三个其它杂原子 基团O，N和S作为环成员，根据描述被取代，L 1 =氟，氯或溴，L 2 = H，烷基或烷氧基，X = 卤素，氰基，烷基，卤代烷基，烷氧基或卤代烷氧基。 本发明还涉及用于生产所述化合物的方法和中间体，包含该化合物的试剂和用于控制对植物有害的真菌害虫的用途。

公开(公告)号：US20070275981A1

公开(公告)日：2007-11-29

申请号：US11661922

申请日：2005-09-05

Applicant: Markus Gewehr ,  Thomas Grote ,  Bernd Muller ,  Wassilios Grammenos ,  Anja Schwogler ,  Joachim Rheinheimer ,  Carsten Blettner ,  Peter Schafer ,  Frank Schieweck ,  Oliver Wagner ,  Jan Rether ,  Siefgried Strathmann ,  Reinhard Stierl ,  Maria Scherer

Inventor： Markus Gewehr ,  Thomas Grote ,  Bernd Muller ,  Wassilios Grammenos ,  Anja Schwogler ,  Joachim Rheinheimer ,  Carsten Blettner ,  Peter Schafer ,  Frank Schieweck ,  Oliver Wagner ,  Jan Rether ,  Siefgried Strathmann ,  Reinhard Stierl ,  Maria Scherer

IPC: A01N43/40 ,  A01N43/54 ,  A01P3/00 ,  C07D239/28 ,  C07D401/04

CPC classification number: A01N43/78 ,  A01N43/56 ,  C07D213/82 ,  C07D231/40 ,  C07D277/56 ,  C07D333/38 ,  C07D401/12 ,  C07D403/12 ,  C07D409/12 ,  C07D417/12

Abstract: The invention relates to the use of (hetero)cyclylcarboxamides of general formula (I) and to the agriculturally useful salts thereof for controlling plant pathogenic fungi, the variables in formula (I) having the following designations: A represents phenyl or an at least monosaturated five-membered or six-membered heterocycle with 1, 2 or 3 heteroatoms as ring members selected from N, O, S, S(═O) and S(═O)2, where phenyl and the at least monosaturated five-membered or six-membered heterocycle can be unsubstituted or substituted according to the description; Y represents oxygen or sulphur; R1 represents H, OH, alkyl, cycloalkyl, alkoxy, halogenalkyl, halogencycloalkyl or halogenalkoxy; R2 and R3 represent H, halogen, nitro, CN, alkyl, cycloalkyl, alkenyl, alkinyl, alkoxy, halogenalkyl, halogencycloalkyl, halogenalkenyl, halogenalkinyl or halogenalkoxy; R4 represents halogen, nitro, CN, alkyl, cycloalkyl, alkenyl, alkinyl, alkoxy, halogenalkyl, halogencycloalkyl, halogenalkenyl, halogenalkinyl or halogenalkoxy; R5 represents hydrogen, halogen, nitro, CN, OH, alkyl, cycloalkyl, alkenyl, alkinyl, alkoxy, alkenyloxy, alkinyloxy, alkoxyalkoxy, halogenalkyl, halogencycloalkyl, halogenalkenyl, halogenalkinyl or halogenalkoxy; alklthio, halogenalkylthio, alkylsulfinyl, halogenalkylsulfinyl, alkylsulfonyl, halogenalkylsulfonyl, —(CR6)═NOR7, —C(O)R8, NR9R10, —C(O)NR9R10, —C(S)NR9R10, phenyl or phenylalkyl, the phenyl ring in the last two radicals optionally comprising between 1 and 4 of the radicals cited for R4; R6, R7, R8, R9 and R10 have the designations cited in the description; the two radicals R4 and R5 bound to adjacent carbon atoms can also represent an alkylene chain with 3 to 5 members, wherein 1 or 2 non-adjacent CH2 groups can also be replaced by O or S, and part or all of the hydrogens can be replaced by halogen; Ar represents phenyl, naphtyl or a five-membered or six-membered heteroaromatic radical with 1, 2 or 3 heteroatoms as ring members selected from N, O, and S, that can optionally also carry a fused benzene ring; and n represents 0, 1, 2, 3, or 4. The invention also relates to crop protection agents containing said compounds.

公开(公告)号：US20070197389A1

公开(公告)日：2007-08-23

申请号：US10589496

申请日：2005-02-24

Applicant: Anja Schwogler ,  Markus Gewehr ,  Bernd Muller ,  Thomas Grote ,  Wassilios Grammenos ,  Jordi Blasco ,  Joachim Rheinheimer ,  Carsten Blettner ,  Peter Schafer ,  Frank Schieweck ,  Oliver Wagner ,  Reinhard Stierl ,  Ulrich Schofl ,  Siegfried Strathmann ,  Maria Scherer

Inventor： Anja Schwogler ,  Markus Gewehr ,  Bernd Muller ,  Thomas Grote ,  Wassilios Grammenos ,  Jordi Blasco ,  Joachim Rheinheimer ,  Carsten Blettner ,  Peter Schafer ,  Frank Schieweck ,  Oliver Wagner ,  Reinhard Stierl ,  Ulrich Schofl ,  Siegfried Strathmann ,  Maria Scherer

IPC: A01N43/713 ,  C07D487/02

CPC classification number: C07D487/04

Abstract: The invention relates to azolopyrimidine compounds of general formula (I), wherein A represents N or C—R6; X and Y, independent of one another, represent a chemical compound or oxygen, sulphur or a group N—R7; the variables R1, R2, R3, R4, R5, R6 and R7 have the meanings cited in the claims and the description. The invention also relates to tautomers of compounds of formula (I) and to the agriculturally compatible salts of compounds (I) and of the tautomers thereof. The invention further relates to the use of azolopyrimidine compounds of general formula (I), to the tautomers thereof and to the agriculturally compatible salts thereof which are used to combat phytopathogenic fungi, and to a method for combating phytopathogenic fungi and means for combating fungi, said means containing at least one compound of general formula (I), a tautomer of formula (I) and/or an agriculturally compatible salt thereof or the tautomer thereof and at least one liquid or solid carrier medium.

Abstract translation: 本发明涉及通式（I）的偶氮嘧啶化合物，其中A代表N或C-R 6; X和Y彼此独立地表示化合物或氧，硫或基团N-R 7; 变量R 1，R 2，R 3，R 4，R 5，...，SUP >，R 6和R 7具有权利要求书和说明书中引用的含义。 本发明还涉及式（I）化合物和化合物（I）的农业相容盐及其互变异构体的互变异构体。 本发明还涉及通式（I）的偶氮嘧啶化合物与其互变异构体及其与植物致病真菌的农业相容盐的用途，以及用于防治植物病原性真菌的方法和对抗真菌的方法， 所述方法含有至少一种通式（I）的化合物，式（I）的互变异构体和/或其农业上相容的盐或其互变异构体和至少一种液体或固体载体介质。

公开(公告)号：US20070185099A1

公开(公告)日：2007-08-09

申请号：US11628852

申请日：2005-06-24

Applicant: Carsten Blettner ,  Frank Schieweck ,  Jordi i Blasco ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schafer ,  Anja Schwogler ,  Oliver Wagner ,  John-Bryan Speakman ,  Thorsten Jabs ,  Siegfried Strathmann ,  Ulrich Schofl ,  Maria Scherer ,  Reinhard Stierl

Inventor： Carsten Blettner ,  Frank Schieweck ,  Jordi i Blasco ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schafer ,  Anja Schwogler ,  Oliver Wagner ,  John-Bryan Speakman ,  Thorsten Jabs ,  Siegfried Strathmann ,  Ulrich Schofl ,  Maria Scherer ,  Reinhard Stierl

IPC: A01N43/90 ,  C07D487/04

CPC classification number: A01N43/90 ,  C07D487/04

Abstract: The present invention relates to novel triazolopyrimidine compounds of the formula I in which: X is halogen, cyano, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy or C1-C2-haloalkoxy; W is oxygen or sulfur; Y is O—R4 or a group NR5R6; A is a chemical bond or a group CR7R8; and the variables L, R1 to R7 are as defined in claim 1. The present invention furthermore provides the use of the triazolopyrimidine compounds of the formula I, their tautomers and their agriculturally acceptable salts for controlling phytopathogenic fungi (=harmful fungi) and a method for controlling phytopathogenic harmful fungi, which method comprises treating the fungi or the materials, plants, the soil or seed to be protected against fungal attack with an effective amount of a compound of the formula I, a tautomer of I and/or an agriculturally acceptable salt of I or a tautomer thereof.

Abstract translation: 本发明涉及新的式I的三唑并嘧啶化合物，其中：X为卤素，氰基，C 1 -C 4 - 烷基，C 1〜 C 1 -C 4 - 低级烷基，C 1 -C 4 - 烷氧基或C 1 -C 3 > 2 - 卤代烷氧基; W是氧或硫; Y是O-R 4或NR 5或R 6基团; A是化学键或基团CR 7 R 8; 变量L，R 1至R 7如权利要求1中所定义。本发明还提供式I的三唑并嘧啶化合物，其互变异构体和 其用于控制​​植物病原真菌（=有害真菌）的农业上可接受的盐和控制植物病原性有害真菌的方法，所述方法包括用有效量的有效量处理待保护的真菌或植物，土壤或种子免受真菌侵袭 式I的化合物，I的互变异构体和/或I的农业上可接受的盐或其互变异构体。

公开(公告)号：US20070155791A1

公开(公告)日：2007-07-05

申请号：US11645319

申请日：2006-12-21

Applicant: Jerome Zeldis ,  Patricia Rohane ,  Peter Schafer

Inventor： Jerome Zeldis ,  Patricia Rohane ,  Peter Schafer

IPC: A61K31/454 ,  A61K31/4035

CPC classification number: A61K31/4035 ,  A61K9/2018 ,  A61K9/4858 ,  A61K9/4866 ,  A61K31/454 ,  A61K31/5575 ,  A61K45/06 ,  A61K2300/00

Abstract: Methods of treating cutaneous lupus in a human are disclosed. Specific methods encompass the administration of (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, 4-(amino)-2-(2,6-dioxo(3-piperidyl))-isoindoline-1,3-dione (ACTIMID™), 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione (REVLIMID®), or cyclopropyl 2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindolin-4-yl}carboxamide, alone or alternatively, in combination with a second active agent.

Abstract translation: 公开了治疗人类皮肤狼疮的方法。 具体方法包括（+） - 2- [1-（3-乙氧基-4-甲氧基苯基）-2-甲基磺酰基乙基] -4-乙酰氨基异二氢吲哚-1,3-二酮，4-（氨基）-2-（2 ，6-二氧代（3-哌啶基）） - 异二氢吲哚-1,3-二酮（ACTIMID TM），3-（4-氨基-1-氧代-1,3-二氢 - 异吲哚-2-基） - 哌啶 -2,6-二酮（REVLIMID）或环丙基2 - [（1S）-1-（3-乙氧基-4-甲氧基苯基）-2-（甲基磺酰基）乙基] -3-氧代异二氢吲哚-4-基} 甲酰胺，单独或替代地，与第二活性剂组合。

公开(公告)号：US20070149400A1

公开(公告)日：2007-06-28

申请号：US10582934

申请日：2004-12-15

Applicant: Jordi Tormo i Blasco ,  Carsten Biettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Oliver Wagner ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

Inventor： Jordi Tormo i Blasco ,  Carsten Biettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Oliver Wagner ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC: A01N43/90 ,  C07D487/04

CPC classification number: C07D487/04 ,  A01N43/90

Abstract: Substituted triazolopyrimidines of the formula I in which the substituents are as defined below: L is hydrogen, chlorine or bromine; R1, R2 are hydrogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, cycloalkenyl, halocycloalkenyl, alkynyl, haloalkynyl or phenyl, naphthyl or a five- or six-membered saturated, partially unsaturated or aromatic heterocycle which contains one to four heteroatoms from the group consisting of O, N and S, R1 and R2 together with the nitrogen atom to which they are attached may also form a five- or six-membered heterocyclyl or heteroaryl which is attached via N and may contain a further heteroatom from the group consisting of O, N and S as ring member and/or may be substituted as defined in the description; R3 is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, halocycloalkyl or phenylalkyl; R1, R2 and/or R3 may be substituted as defined in the description; X is halogen, cyano, alkyl, haloalkyl, alkoxy or haloalkoxy; processes and intermediates for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi.

Abstract translation: 取代基如下定义的式I的取代三唑并嘧啶：L是氢，氯或溴; R 1，R 2是氢，烷基，卤代烷基，环烷基，卤代环烷基，烯基，卤代烯基，环烯基，卤代环烯基，炔基，卤代炔基或苯基，萘基或五或 含有一至四个由O，N和S杂原子组成的组的六元饱和，部分不饱和或芳族杂环，R 1和R 2连同氮 它们所连接的原子也可以形成通过N连接的五元或六元杂环基或杂芳基，并且可以含有作为环成员的O，N和S中的另外的杂原子和/或可被取代为 在说明书中定义; R 3是烷基，卤代烷基，烯基，卤代烯基，炔基，卤代炔基，环烷基，卤代环烷基或苯基烷基; R 1，R 2和/或R 3可以如说明书中所定义的取代; X是卤素，氰基，烷基，卤代烷基，烷氧基或卤代烷氧基; 制备这些化合物的方法和中间体，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。