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1.发明授权Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use 有权对双链DNA具有高选择性的荧光化合物及其使用方法公开(公告)号：US07943777B2
公开(公告)日：2011-05-17
申请号：US12573809
申请日：2009-10-05
IPC分类号： C07D417/00 , C07D215/00 , C07D251/38
CPC分类号： G01N33/582 , C07D215/10 , C07D215/227 , C07D277/72 , C07D277/74 , C07D417/04 , C07D417/06 , C07D417/14 , C12Q1/6876 , G01N21/6428 , G01N21/6486 , G01N2021/6439 , G01N2201/06113 , Y10T436/143333
摘要： Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.
摘要翻译： 公开了对RNA和单链DNA具有对双链DNA的高选择性的化合物。 化学化合物是在照射时变成荧光并与双链DNA相互作用的污渍，但在不存在双链DNA的情况下表现出减少的或没有荧光。 该化合物可用于各种生物学应用中，以定性或定量测定DNA，即使在RNA的存在下。
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2.发明申请Flourescent chemical compounds having high selectivity for double standard DNA, and methods for their use 有权对双标准DNA具有高选择性的荧光化合物及其使用方法公开(公告)号：US20060263844A1
公开(公告)日：2006-11-23
申请号：US11432814
申请日：2006-05-11
IPC分类号： C12Q1/02
CPC分类号： G01N33/582 , C07D215/10 , C07D215/227 , C07D277/72 , C07D277/74 , C07D417/04 , C07D417/06 , C07D417/14 , C12Q1/6876 , G01N21/6428 , G01N21/6486 , G01N2021/6439 , G01N2201/06113 , Y10T436/143333
摘要： Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.
摘要翻译： 公开了对RNA和单链DNA具有对双链DNA的高选择性的化合物。 化学化合物是在照射时变成荧光并与双链DNA相互作用的污渍，但在不存在双链DNA的情况下表现出减少的或没有荧光。 该化合物可用于各种生物学应用中，以定性或定量测定DNA，即使在RNA的存在下。
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