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公开(公告)号:US07332511B2
公开(公告)日:2008-02-19
申请号:US11195159
申请日:2005-08-01
申请人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Hui-Ling Wang , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Celia Dominguez , James Richard Falsey , Christopher Hulme , Jodie Katon , Thomas Nixey , Vassil I. Ognyanov , Liping H. Pettus , Robert Michael Rzasa
发明人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Hui-Ling Wang , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Celia Dominguez , James Richard Falsey , Christopher Hulme , Jodie Katon , Thomas Nixey , Vassil I. Ognyanov , Liping H. Pettus , Robert Michael Rzasa
IPC分类号: C07D213/30 , C07D213/32 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , A61K31/4427 , A61P19/02 , A61P35/00
CPC分类号: C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12
摘要: Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
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2.Method and apparatus for operational-level functional and degradation fault analysis 失效
标题翻译: 操作级功能和劣化故障分析的方法和装置公开(公告)号:US08108728B2
公开(公告)日:2012-01-31
申请号:US12753166
申请日:2010-04-02
IPC分类号: G06F11/00
CPC分类号: G06F17/504 , G06F2217/70
摘要: An apparatus and method are provided for analyzing fault tolerance of a system, and performing “what if?” analysis for various fault-tolerant system design options. The fault tolerance analysis approach handles logical failures and quality faults emanating from loss of precision in signal values. The method can detect quality faults, which can allow systems to be built which are resilient to precision losses. Two analysis steps are provided, one static and another simulation-based, which are used in tandem to check the fault tolerance of an automotive or other system. While a simulation-based method checks fault-resilience under specific test cases and fault-scenarios, the static analysis method quickly checks all test cases and fault-scenarios. The static analysis method makes approximations while performing the analysis, and any fault detected is reproduced using the simulation-based method. All analysis operations are performed on operations-level behavioral models of the applications, thereby reducing the cost of analysis.
摘要翻译: 提供了一种用于分析系统的容错性并对各种容错系统设计选项执行“如果?”分析的装置和方法。 容错分析方法处理信号值精度损失所产生的逻辑故障和质量故障。 该方法可以检测质量故障,这可以允许建立能够抵御精度损失的系统。 提供了两个分析步骤,一个静态和另一个基于模拟,它们一起用于检查汽车或其他系统的容错。 虽然基于仿真的方法会检查特定测试用例和故障场景下的故障恢复能力,静态分析方法可快速检查所有测试用例和故障场景。 静态分析方法在执行分析时进行近似,并且使用基于模拟的方法再现所检测到的任何故障。 所有分析操作都在应用程序的操作级行为模型上执行,从而降低了分析成本。
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公开(公告)号:US07053088B2
公开(公告)日:2006-05-30
申请号:US10445170
申请日:2003-05-20
申请人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Vassil I. Ognyanov , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Liping H. Pettus , Hui-Ling Wang , Xianghong Wang , Premilla Arasasingham
发明人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Vassil I. Ognyanov , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Liping H. Pettus , Hui-Ling Wang , Xianghong Wang , Premilla Arasasingham
IPC分类号: A61K31/50
CPC分类号: C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要: Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
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公开(公告)号:US20050267163A1
公开(公告)日:2005-12-01
申请号:US11195302
申请日:2005-08-01
申请人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Vassil I. Ognyanov , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Liping H. Pettus , Hui-Ling Wang , Xianghong Wang , Premilla Arasasingham
发明人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Vassil I. Ognyanov , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Liping H. Pettus , Hui-Ling Wang , Xianghong Wang , Premilla Arasasingham
IPC分类号: A61K31/4709 , A61K31/501 , A61K31/505 , A61K31/506 , A61K31/5377 , A61P1/00 , A61P1/04 , A61P9/00 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/00 , A61P15/00 , A61P17/00 , A61P17/02 , A61P17/06 , A61P17/14 , A61P19/02 , A61P25/00 , A61P25/02 , A61P25/04 , A61P25/06 , A61P27/02 , A61P29/00 , A61P37/08 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/64 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/22 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , A61K31/4439 , C07D413/02 , C07D417/02 , C07D43/02
CPC分类号: C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要: Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
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公开(公告)号:US07144888B2
公开(公告)日:2006-12-05
申请号:US10638009
申请日:2003-08-08
申请人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Hui-Ling Wang , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Celia Dominguez , James Richard Falsey , Christopher Hulme , Jodie Katon , Thomas Nixey , Vassil I. Ognyanov , Liping H. Pettus , Robert Michael Rzasa
发明人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Hui-Ling Wang , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Celia Dominguez , James Richard Falsey , Christopher Hulme , Jodie Katon , Thomas Nixey , Vassil I. Ognyanov , Liping H. Pettus , Robert Michael Rzasa
IPC分类号: C07D239/34 , C07D239/38 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , A61K31/505 , A61K31/506 , A61K31/4427 , A61P19/02 , A61P25/06
CPC分类号: C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12
摘要: Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
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公开(公告)号:US07396831B2
公开(公告)日:2008-07-08
申请号:US11195303
申请日:2005-08-01
申请人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Vassil I. Ognyanov , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Liping H. Pettus , Hui-Ling Wang , Xianghong Wang , Premilla Arasasingham
发明人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Vassil I. Ognyanov , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Liping H. Pettus , Hui-Ling Wang , Xianghong Wang , Premilla Arasasingham
IPC分类号: C07D403/12 , C07D403/14 , A61K31/501
CPC分类号: C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要: Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
摘要翻译: 具有一般结构和含有它们的组合物的化合物,用于治疗急性,炎性和神经性疼痛,牙痛,一般头痛,偏头痛,丛集性头痛,混合血管和非血管综合征,紧张性头痛,一般炎症,关节炎,风湿性 疾病,骨关节炎,炎症性肠病,炎症性眼病,炎症性或不稳定性膀胱病,银屑病,皮肤炎症成分炎症,慢性炎性病症,炎性疼痛及相关的痛觉过敏和异常性疼痛,神经性疼痛及相关的痛觉过敏和异常性疼痛,糖尿病性神经病疼痛, 咳嗽痛,交感神经痛,交感综合征,哮喘,上皮组织损伤或功能障碍,单纯疱疹,呼吸道内脏运动紊乱,泌尿生殖道,胃肠道或血管区,伤口,烧伤,过敏性皮肤反应,瘙痒症,白癜风,一般胃肠道疾病, G 腹部溃疡,十二指肠溃疡,腹泻,坏死因子诱发的胃损伤,毛发生长,血管舒缩或过敏性鼻炎,支气管疾病或膀胱疾病。
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公开(公告)号:US07301022B2
公开(公告)日:2007-11-27
申请号:US11354650
申请日:2006-02-15
申请人: Yunxin Y. Bo , Partha P. Chakrabarti , Ning Chen , Hongyu Liao , Mark H. Norman , Markian Stec , Nuria Tamayo , Xianghong Wang
发明人: Yunxin Y. Bo , Partha P. Chakrabarti , Ning Chen , Hongyu Liao , Mark H. Norman , Markian Stec , Nuria Tamayo , Xianghong Wang
IPC分类号: C07D239/34 , C07D239/38 , C07D237/14 , C07D237/18 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , A61K31/505 , A61K31/506 , A61K31/4427 , A61P19/02 , A61P35/00
CPC分类号: C07D403/14 , C07D401/14 , C07D417/12 , C07D417/14
摘要: Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
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公开(公告)号:US07148221B2
公开(公告)日:2006-12-12
申请号:US11195134
申请日:2005-08-01
申请人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Hui-Ling Wang , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Celia Dominguez , James Richard Falsey , Christopher Hulme , Jodie Katon , Thomas Nixey , Vassil I. Ognyanov , Liping H. Pettus , Robert Michael Rzasa
发明人: Elizabeth M. Doherty , Jiawang Zhu , Markian Stec , Mark H. Norman , Hui-Ling Wang , Christopher H. Fotsch , Ning Chen , Partha P. Chakrabarti , Celia Dominguez , James Richard Falsey , Christopher Hulme , Jodie Katon , Thomas Nixey , Vassil I. Ognyanov , Liping H. Pettus , Robert Michael Rzasa
IPC分类号: C07D237/14 , C07D237/18 , C07D223/16 , C07D223/18 , A61K31/501 , A61P25/06
CPC分类号: C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12
摘要: Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
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9.METHOD AND APPARATUS FOR OPERATIONAL-LEVEL FUNCTIONAL AND DEGRADATION FAULT ANALYSIS 失效
标题翻译: 操作级功能和降解故障分析的方法和装置公开(公告)号:US20110246831A1
公开(公告)日:2011-10-06
申请号:US12753166
申请日:2010-04-02
IPC分类号: G06F11/07
CPC分类号: G06F17/504 , G06F2217/70
摘要: An apparatus and method are provided for analyzing fault tolerance of a system, and performing “what if?” analysis for various fault-tolerant system design options. The fault tolerance analysis approach handles logical failures and quality faults emanating from loss of precision in signal values. The method can detect quality faults, which can allow systems to be built which are resilient to precision losses. Two analysis steps are provided, one static and another simulation-based, which are used in tandem to check the fault tolerance of an automotive or other system. While a simulation-based method checks fault-resilience under specific test cases and fault-scenarios, the static analysis method quickly checks all test cases and fault-scenarios. The static analysis method makes approximations while performing the analysis, and any fault detected is reproduced using the simulation-based method. All analysis operations are performed on operations-level behavioral models of the applications, thereby reducing the cost of analysis.
摘要翻译: 提供了一种用于分析系统的容错性并对各种容错系统设计选项执行“如果?”分析的装置和方法。 容错分析方法处理信号值精度损失所产生的逻辑故障和质量故障。 该方法可以检测质量故障,这可以允许建立能够抵御精度损失的系统。 提供了两个分析步骤,一个静态和另一个基于模拟,它们一起用于检查汽车或其他系统的容错。 虽然基于仿真的方法会检查特定测试用例和故障场景下的故障恢复能力,静态分析方法可快速检查所有测试用例和故障场景。 静态分析方法在执行分析时进行近似,并且使用基于模拟的方法再现所检测到的任何故障。 所有分析操作都在应用程序的操作级行为模型上执行,从而降低了分析成本。
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公开(公告)号:US20090264424A1
公开(公告)日:2009-10-22
申请号:US12492376
申请日:2009-06-26
申请人: Yunxin Y. Bo , Partha P. Chakrabarti , Ning Chen , Elizabeth M. Doherty , Christopher H. Fotsch , Nianhe Han , Michael G. Kelly , Qingyian Liu , Mark Henry Norman , Vassil I. Ognyanov , Xianghong Wang , Jiawang Zhu
发明人: Yunxin Y. Bo , Partha P. Chakrabarti , Ning Chen , Elizabeth M. Doherty , Christopher H. Fotsch , Nianhe Han , Michael G. Kelly , Qingyian Liu , Mark Henry Norman , Vassil I. Ognyanov , Xianghong Wang , Jiawang Zhu
IPC分类号: A61K31/536 , C07D265/36 , A61P29/00
CPC分类号: C07D471/04 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要: Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
摘要翻译: 具有一般结构和含有它们的组合物的化合物,用于治疗急性,炎性和神经性疼痛,牙痛,一般头痛,偏头痛,丛集性头痛,混合血管和非血管综合征,紧张性头痛,一般炎症,关节炎,风湿性 疾病,骨关节炎,炎症性肠病,炎症性眼病,炎症性或不稳定性膀胱病,银屑病,皮肤炎症成分炎症,慢性炎性病症,炎性疼痛及相关的痛觉过敏和异常性疼痛,神经性疼痛及相关的痛觉过敏和异常性疼痛,糖尿病性神经病疼痛, 咳嗽痛,交感神经痛,交感综合征,哮喘,上皮组织损伤或功能障碍,单纯疱疹,呼吸道内脏运动紊乱,泌尿生殖道,胃肠道或血管区,伤口,烧伤,过敏性皮肤反应,瘙痒症,白癜风,一般胃肠道疾病, G 腹部溃疡,十二指肠溃疡,腹泻,坏死因子诱发的胃损伤,毛发生长,血管舒缩或过敏性鼻炎,支气管疾病或膀胱疾病。
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