公开(公告)号：US20080081343A1

公开(公告)日：2008-04-03

申请号：US11649744

申请日：2007-01-04

Applicant: Paul Haynes ,  Jing Wei ,  John Yates ,  Nancy Andon ,  Michael P. Washburn ,  Cosmin Deciu ,  Ryan U. Ulaszek

Inventor： Paul Haynes ,  Jing Wei ,  John Yates ,  Nancy Andon ,  Michael P. Washburn ,  Cosmin Deciu ,  Ryan U. Ulaszek

IPC: G01N33/53

CPC classification number: G01N33/6803 ,  C07K1/13 ,  C07K14/395 ,  G01N33/6815 ,  G01N33/6842 ,  G01N33/6848 ,  G01N2458/15 ,  G01N2550/00

Abstract: The disclosed subject matter relates to a method of simultaneously identifying and determining the levels of expression of cysteine-containing proteins in normal and perturbed cells, a method for determining peptide expression levels between a first biological sample and a second biological sample, and a method for quantitative proteomic analysis of two or more peptide populations, and compounds and reagents related thereto.

Abstract translation: 所公开的主题涉及同时鉴定和确定正常和扰动细胞中含半胱氨酸的蛋白质的表达水平的方法，用于测定第一生物样品和第二生物样品之间的肽表达水平的方法，以及用于 两个或多个肽群体的定量蛋白质组学分析，以及与其相关的化合物和试剂。