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公开(公告)号：US09627097B2
公开(公告)日：2017-04-18
申请号：US10792683
申请日：2004-03-02
Applicant: Mark Alan Jackson , Paritosh Jayant Dhawale , Hernan Rodrigo Lara , Michael Brussermann , Ulrich Ketzscher
Inventor： Mark Alan Jackson , Paritosh Jayant Dhawale , Hernan Rodrigo Lara , Michael Brussermann , Ulrich Ketzscher
IPC: A61B6/00 , A61M5/00 , G21F5/018 , G01T1/00 , G21G4/08 , G21H5/02 , A61M5/172 , A61M5/178 , G06F19/00 , A61B6/03
CPC classification number: G21F5/018 , A61B6/037 , A61B6/548 , A61M5/007 , A61M5/172 , A61M5/1785 , G01T1/00 , G06F19/00 , G06F19/3481 , G16H40/63 , G21G4/08 , G21H5/02
Abstract: Systems, apparatus and methods are provided through which an injector system automates a process of injecting an individual dose from a multiple dose of a radiotracer material. In some embodiments, the injector system includes a first dose calibrator system that receives a multidose vial of a radiotracer, a second dose calibrator system, an injection pump and an intravenous needle. In some embodiments, the first dose calibrator system and the multidose vial have an integrated shape. In some embodiments, the first dose calibrator system includes a pneumatic arm that receives the multidose vial.
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2.发明申请公开(公告)号：US20100264326A1
公开(公告)日：2010-10-21
申请号：US12713954
申请日：2010-02-26
Applicant: Michael Brussermann , Guido Schwartenbeck , Stefan Riese
Inventor： Michael Brussermann , Guido Schwartenbeck , Stefan Riese
IPC: G01T1/00
CPC classification number: G01N5/04 , G01N1/38 , Y10T436/11 , Y10T436/13
Abstract: A system and method for measurement of radioactivity concentration of a radiopharmaceutical are disclosed. The radiopharmaceutical may be a radioactive tracer solution including a tracer solution and a buffer solution. The system may include a vial that receives the tracer solution and the buffer solution; a scale; a radioactivity measuring device; and a controller that determines the radioactive concentration based on a measured radioactivity of the tracer solution and the buffer solution in the vial, and a weight of the tracer solution and the buffer solution in the vial. The method may include the steps of (1) transferring the tracer solution into a vial; (2) measuring a radioactivity of the tracer solution in the vial; (3) determining a weight necessary to achieve a desired radioactivity concentration; and (4) diluting the tracer solution in the vial to the determined weight with a buffer solution.
Abstract translation: 公开了用于测量放射性药物的放射性浓度的系统和方法。 放射性药物可以是包括示踪剂溶液和缓冲溶液的放射性示踪剂溶液。 系统可以包括接收示踪剂溶液和缓冲溶液的小瓶; 规模 放射性测量装置; 以及控制器，其基于测量的示踪剂溶液和小瓶中的缓冲溶液的放射性以及示踪剂溶液和小瓶中的缓冲溶液的重量来确定放射性浓度。 该方法可以包括以下步骤：（1）将示踪剂溶液转移到小瓶中; （2）测量小瓶中示踪剂溶液的放射性; （3）确定实现所需放射性浓度所需的重量; 和（4）用缓冲溶液将小瓶中的示踪剂溶液稀释至确定的重量。
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3.发明申请SYSTEMS, METHODS AND APPARATUS FOR PREPARATION, DELIVERY AND MONITORING OF RADIOPHARMACEUTICALS 审中-公开放射性物质的制备，输送和监测的系统，方法和装置公开(公告)号：US20100286512A1
公开(公告)日：2010-11-11
申请号：US12781543
申请日：2010-05-17
Applicant: Paritosh Jayant Dhawale , Mark Alan Jackson , Hernan Rodrigo Lara , Michael Brussermann , Ulrich Ketzscher
Inventor： Paritosh Jayant Dhawale , Mark Alan Jackson , Hernan Rodrigo Lara , Michael Brussermann , Ulrich Ketzscher
CPC classification number: G21F5/018 , A61B6/037 , A61B6/548 , A61M5/007 , A61M5/172 , A61M5/1785 , G01T1/00 , G06F19/3481 , G16H40/63 , G21G4/08 , G21H5/02
Abstract: In one aspect, systems, methods and apparatus are provided through which a dispensing station dispenses a large quantity of a radiotracer to one or more positron emission tomography imaging stations. In some aspects a quality control unit verifies the quality of the radiotracer. In some embodiments, components of the system are coupled by a local area network. In some aspects, each positron emission tomography imaging station includes an injector system, a physiological monitoring device, and a positron emission tomography scanner. All of the devices can be controlled by a computer system.
Abstract translation: 在一个方面，提供了一种系统，方法和设备，通过该系统，方法和装置，分配站将大量的放射性示踪器分配给一个或多个正电子发射断层摄影成像站。 在某些方面，质量控制单元验证放射性示踪器的质量。 在一些实施例中，系统的组件由局域网耦合。 在一些方面，每个正电子发射断层摄影成像站包括注射器系统，生理监测装置和正电子发射断层扫描仪。 所有的设备都可以由计算机系统控制。
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Patent Agency Ranking
4.发明申请SYSTEMS, METHODS AND APPARATUS FOR PREPARATION, DELIVERY AND MONITORING OF RADIOISOTOPES IN POSITRON EMISSION TOMOGRAPHY 有权系统，方法和装置，用于放射性摄影术中放射性物质的制备，输送和监测公开(公告)号：US20100121184A1
公开(公告)日：2010-05-13
申请号：US10792029
申请日：2004-03-02
Applicant: Paritosh Jayant Dhawale , Mark Alan Jackson , Hernan Rodrigo Lara , Michael Brussermann , Ulrich Ketzscher
Inventor： Paritosh Jayant Dhawale , Mark Alan Jackson , Hernan Rodrigo Lara , Michael Brussermann , Ulrich Ketzscher
CPC classification number: G21F5/018 , A61B6/037 , A61B6/548 , A61M5/007 , A61M5/172 , A61M5/1785 , G01T1/00 , G06F19/00 , G06F19/3481 , G16H40/63 , G21G4/08 , G21H5/02
Abstract: In one aspect, systems, methods and apparatus are provided through which a dispensing station dispenses a large quantity of a radiotracer to one or more positron emission tomography imaging stations. In some aspects a quality control unit verifies the quality of the radiotracer. In some embodiments, components of the system are coupled by a local area network. In some aspects, each positron emission tomography imaging station includes an injector system, a physiological monitoring device, and a positron emission tomography scanner. All of the devices can be controlled by a computer system.
Abstract translation: 在一个方面，提供了一种系统，方法和设备，通过该系统，方法和装置，分配站将大量的放射性示踪器分配给一个或多个正电子发射断层摄影成像站。 在某些方面，质量控制单元验证放射性示踪器的质量。 在一些实施例中，系统的组件由局域网耦合。 在一些方面，每个正电子发射断层摄影成像站包括注射器系统，生理监测装置和正电子发射断层扫描仪。 所有的设备都可以由计算机系统控制。
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公开(公告)号：US20080242915A1
公开(公告)日：2008-10-02
申请号：US10792683
申请日：2004-03-02
Applicant: Mark Alan Jackson , Paritosh Jayant Dhawale , Hernan Rodrigo Lara , Michael Brussermann , Ulrich Ketzscher
Inventor： Mark Alan Jackson , Paritosh Jayant Dhawale , Hernan Rodrigo Lara , Michael Brussermann , Ulrich Ketzscher
IPC: A61M36/06
CPC classification number: G21F5/018 , A61B6/037 , A61B6/548 , A61M5/007 , A61M5/172 , A61M5/1785 , G01T1/00 , G06F19/00 , G06F19/3481 , G16H40/63 , G21G4/08 , G21H5/02
Abstract: Systems, apparatus and methods are provided through which an injector system automates a process of injecting an individual dose from a multiple dose of a radiotracer material. In some embodiments, the injector system includes a first dose calibrator system that receives a multidose vial of a radiotracer, a second dose calibrator system, an injection pump and an intravenous needle. In some embodiments, the first dose calibrator system and the multidose vial have an integrated shape. In some embodiments, the first dose calibrator system includes a pneumatic arm that receives the multidose vial.
Abstract translation: 提供了系统，装置和方法，通过该系统，装置和方法，注射器系统自动化从多剂量的放射性示踪剂材料注入单个剂量的过程。 在一些实施例中，注射器系统包括第一剂量校准器系统，其接收放射性示踪器，第二剂量校准器系统，注射泵和静脉注射针的多剂量小瓶。 在一些实施例中，第一剂量校准器系统和多剂量小瓶具有整体形状。 在一些实施例中，第一剂量校准器系统包括接收多剂量小瓶的气动臂。
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6.发明授权System and method for measurement of radioactivity concentration of a radiopharmaceutical 有权用于测量放射性药物的放射性浓度的系统和方法公开(公告)号：US08260559B2
公开(公告)日：2012-09-04
申请号：US12713954
申请日：2010-02-26
Applicant: Michael Brussermann , Guido Schwartenbeck , Stefan Riese
Inventor： Michael Brussermann , Guido Schwartenbeck , Stefan Riese
CPC classification number: G01N5/04 , G01N1/38 , Y10T436/11 , Y10T436/13
Abstract: A system and method for measurement of radioactivity concentration of a radiopharmaceutical are disclosed. The radiopharmaceutical may be a radioactive tracer solution including a tracer solution and a buffer solution. The system may include a vial that receives the tracer solution and the buffer solution; a scale; a radioactivity measuring device; and a controller that determines the radioactive concentration based on a measured radioactivity of the tracer solution and the buffer solution in the vial, and a weight of the tracer solution and the buffer solution in the vial. The method may include the steps of (1) transferring the tracer solution into a vial; (2) measuring a radioactivity of the tracer solution in the vial; (3) determining a weight necessary to achieve a desired radioactivity concentration; and (4) diluting the tracer solution in the vial to the determined weight with a buffer solution.
Abstract translation: 公开了用于测量放射性药物的放射性浓度的系统和方法。 放射性药物可以是包括示踪剂溶液和缓冲溶液的放射性示踪剂溶液。 系统可以包括接收示踪剂溶液和缓冲溶液的小瓶; 规模 放射性测量装置; 以及控制器，其基于测量的示踪剂溶液和小瓶中的缓冲溶液的放射性以及示踪剂溶液和小瓶中的缓冲溶液的重量来确定放射性浓度。 该方法可以包括以下步骤：（1）将示踪剂溶液转移到小瓶中; （2）测量小瓶中示踪剂溶液的放射性; （3）确定实现所需放射性浓度所需的重量; 和（4）用缓冲溶液将小瓶中的示踪剂溶液稀释至确定的重量。
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7.发明授权Systems, methods and apparatus for preparation, delivery and monitoring of radioisotopes in positron emission tomography 有权正电子发射断层扫描中放射性同位素的制备，传递和监测系统，方法和装置公开(公告)号：US07734331B2
公开(公告)日：2010-06-08
申请号：US10792029
申请日：2004-03-02
Applicant: Paritosh Jayant Dhawale , Mark Alan Jackson , Hernan Rodrigo Lara , Michael Brussermann , Ulrich Ketzscher
Inventor： Paritosh Jayant Dhawale , Mark Alan Jackson , Hernan Rodrigo Lara , Michael Brussermann , Ulrich Ketzscher
CPC classification number: G21F5/018 , A61B6/037 , A61B6/548 , A61M5/007 , A61M5/172 , A61M5/1785 , G01T1/00 , G06F19/00 , G06F19/3481 , G16H40/63 , G21G4/08 , G21H5/02
Abstract: In one aspect, systems, methods and apparatus are provided through which a dispensing station dispenses a large quantity of a radiotracer to one or more positron emission tomography imaging stations. In some aspects a quality control unit verifies the quality of the radiotracer. In some embodiments, components of the system are coupled by a local area network. In some aspects, each positron emission tomography imaging station includes an injector system, a physiological monitoring device, and a positron emission tomography scanner. All of the devices can be controlled by a computer system.
Abstract translation: 在一个方面，提供了一种系统，方法和设备，通过该系统，方法和装置，分配站将大量的放射性示踪器分配给一个或多个正电子发射断层摄影成像站。 在某些方面，质量控制单元验证放射性示踪器的质量。 在一些实施例中，系统的组件由局域网耦合。 在一些方面，每个正电子发射断层摄影成像站包括注射器系统，生理监测装置和正电子发射断层扫描仪。 所有的设备都可以由计算机系统控制。
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公开(公告)号：US20070251299A1
公开(公告)日：2007-11-01
申请号：US11411771
申请日：2006-04-27
Applicant: Michael Brussermann , Josef Duhnen , Stefan Riese
Inventor： Michael Brussermann , Josef Duhnen , Stefan Riese
IPC: G01N15/08
CPC classification number: A61L2/28 , B01D46/0012 , B01D2273/18 , G01N15/0826 , G01N2015/084
Abstract: The invention relates to a method for in-process integrity test of a filter. The method may comprise the steps of: coupling a gas source to an input side of a filter without removing the filter from a dispenser system, the gas source supplying a gas and controlling a pressure of the gas; coupling a tube to an output side of the filter, the tube being filled with a liquid; increasing the pressure while monitoring the tube, with a light beam, for a displacement of the liquid by one or more gas bubbles; and determining a value of the pressure at which the displacement of the liquid is detected.
Abstract translation: 本发明涉及一种过滤器的过程内完整性测试方法。 该方法可以包括以下步骤：将气体源连接到过滤器的输入侧，而不从分配器系统移除过滤器，气体源供应气体并控制气体的压力; 将管连接到过滤器的输出侧，管被填充液体; 在用光束监测管时增加压力，以通过一个或多个气泡排出液体; 并且确定检测到液体的位移的压力的值。
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