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公开(公告)号：US08637294B2
公开(公告)日：2014-01-28
申请号：US11728219
申请日：2007-03-22
Applicant: Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
Inventor： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
CPC classification number: C12N9/2437 , C11D3/38645 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , D21C5/005 , Y02E50/16
Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
Abstract translation: 本文描述的是H.jecorina CBH I，Cel7酶的变体。 本发明提供了具有改善的热稳定性和可逆性的新型纤维二糖水解酶。
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公开(公告)号：US08232080B2
公开(公告)日：2012-07-31
申请号：US13107702
申请日：2011-05-13
Applicant: Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
Inventor： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
CPC classification number: C12N9/2437 , C11D3/38645 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , D21C5/005 , Y02E50/16
Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
Abstract translation: 本文描述的是H.jecorina CBH I，Cel7酶的变体。 本发明提供了具有改善的热稳定性和可逆性的新型纤维二糖水解酶。
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公开(公告)号：US20110229956A1
公开(公告)日：2011-09-22
申请号：US13107702
申请日：2011-05-13
Applicant: Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
Inventor： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
CPC classification number: C12N9/2437 , C11D3/38645 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , D21C5/005 , Y02E50/16
Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
Abstract translation: 本文描述的是H.jecorina CBH I，Cel7酶的变体。 本发明提供了具有改善的热稳定性和可逆性的新型纤维二糖水解酶。
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公开(公告)号：US07972832B2
公开(公告)日：2011-07-05
申请号：US10641678
申请日：2003-08-15
Applicant: Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
Inventor： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
CPC classification number: C12N9/2437 , C11D3/38645 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , D21C5/005 , Y02E50/16
Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
Abstract translation: 本文描述的是H.jecorina CBH I，Cel7酶的变体。 本发明提供了具有改善的热稳定性和可逆性的新型纤维二糖水解酶。
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公开(公告)号：US20070173431A1
公开(公告)日：2007-07-26
申请号：US11728219
申请日：2007-03-22
Applicant: Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
Inventor： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
CPC classification number: C12N9/2437 , C11D3/38645 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , D21C5/005 , Y02E50/16
Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
Abstract translation: 本文描述的是H.jecorina CBH I，Cel7酶的变体。 本发明提供了具有改善的热稳定性和可逆性的新型纤维二糖水解酶。
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Patent Agency Ranking
公开(公告)号：US20050277172A1
公开(公告)日：2005-12-15
申请号：US10641678
申请日：2003-08-15
Applicant: Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
Inventor： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
CPC classification number: C12N9/2437 , C11D3/38645 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , D21C5/005 , Y02E50/16
Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
Abstract translation: 本文描述的是H.jecorina CBH I，Cel7酶的变体。 本发明提供了具有改善的热稳定性和可逆性的新型纤维二糖水解酶。
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公开(公告)号：US20190161521A1
公开(公告)日：2019-05-30
申请号：US16301075
申请日：2017-05-08
Applicant: Torleif Härd , Mats Sandgren , Benjamin Schmuck
Inventor： Torleif Härd , Mats Sandgren , Benjamin Schmuck
IPC: C07K14/395 , C07K16/06 , G01N33/531
Abstract: The present embodiments relate to antibody binding nanofibrils obtainable by co-fibrillation of carrier proteins and carrier-Z fusion proteins at a molar ratio selected within an interval of from 1:0.20 to :0.90. The antibody binding nanofibrils have extremely high antibody binding capacity and can thereby be used in various applications, such as antibody purification, and detection of biomarkers in point of care or laboratory diagnosis applications.
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公开(公告)号：US11066452B2
公开(公告)日：2021-07-20
申请号：US16301075
申请日：2017-05-08
Applicant: Torleif Härd , Mats Sandgren , Benjamin Schmuck
Inventor： Torleif Härd , Mats Sandgren , Benjamin Schmuck
IPC: G01N33/531 , C07K14/395 , C07K14/31 , C07K16/00 , C07K1/22 , C07K16/06
Abstract: The present embodiments relate to antibody binding nanofibrils obtainable by co-fibrillation of carrier proteins and carrier-Z fusion proteins at a molar ratio selected within an interval of from 1:0.20 to 1:0.90. The antibody binding nanofibrils have extremely high antibody binding capacity and can thereby be used in various applications, such as antibody purification, and detection of biomarkers in point of care or laboratory diagnosis applications.
(FIG. 6).-
公开(公告)号：US09447400B2
公开(公告)日：2016-09-20
申请号：US13510902
申请日：2010-11-19
Applicant: Richard R. Bott , Thijs Kaper , Bradley Kelemen , Frits Goedegebuur , Ronaldus Wilhelmus Hommes , Slavko Kralj , Paulien Kruithof , Igor Nikolaev , Wilhelmus Antonious Hendricus Van Der Kley , Johannes Franciscus Thomas Van Lieshout , Sander Van Stigt Thans , Gudrun Vogtentanz , Mats Sandgren
Inventor： Richard R. Bott , Thijs Kaper , Bradley Kelemen , Frits Goedegebuur , Ronaldus Wilhelmus Hommes , Slavko Kralj , Paulien Kruithof , Igor Nikolaev , Wilhelmus Antonious Hendricus Van Der Kley , Johannes Franciscus Thomas Van Lieshout , Sander Van Stigt Thans , Gudrun Vogtentanz , Mats Sandgren
CPC classification number: C12N9/2445 , C12N15/52 , C12P19/02 , C12P19/14 , C12Y302/01021
Abstract: The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.
Abstract translation: 本公开通常涉及酶，特别是β-葡糖苷酶变体。 还描述了编码β-葡糖苷酶变体的核酸，包含β-葡糖苷酶变体的组合物，使用β-葡糖苷酶变体的方法和鉴定另外有用的β-葡糖苷酶变体的方法。
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公开(公告)号：US08679817B2
公开(公告)日：2014-03-25
申请号：US13523800
申请日：2012-06-14
Applicant: Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe-Kruithof , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
Inventor： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe-Kruithof , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
CPC classification number: C12N9/2437 , C11D3/38645 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , D21C5/005 , Y02E50/16
Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
Abstract translation: 本文描述的是H.jecorina CBH I，Cel7酶的变体。 本发明提供了具有改善的热稳定性和可逆性的新型纤维二糖水解酶。
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