摘要:
Provided is a novel useful microRNA having improved anti-tumor activity, obtained by introducing a variation in a microRNA which is present in-vivo and which exhibits an anti-tumor effect. This microRNA containing a base sequence (SEQ ID NO: 1) obtained by varying a predetermined region of the base sequence of miR-29b is able to exhibit a particularly outstanding anti-tumor effect.
摘要:
An object of the present invention is to provide an agent that potentiates the antitumor effect of an anticancer agent by allowing efficient accumulation of the anticancer agent in tumor tissue. The administration of carbonate apatite with the anticancer agent allows efficient accumulation of the anticancer agent in the tumor tissue to dramatically potentiate the antitumor effect of the anticancer agent.
摘要:
An object of the present invention is to provide an agent that potentiates the antitumor effect of an anticancer agent by allowing efficient accumulation of the anticancer agent in tumor tissue. The administration of carbonate apatite with the anticancer agent allows efficient accumulation of the anticancer agent in the tumor tissue to dramatically potentiate the antitumor effect of the anticancer agent.
摘要:
An object of the present invention is to provide a pancreatic islet transplantation technique that enables increase of graft survival rate of pancreatic islets after pancreatic islet transplantation, to maintain survival of pancreatic islets, and to reduce the number of transplanted pancreatic islets required for normalizing blood glucose level. When performing pancreatic islet transplantation, by transplanting pancreatic islets and adipose tissue-derived stem cells together, it is possible to significantly improve graft survival rate of transplanted pancreatic islets, and reduce by half the number of transplanted pancreatic islets required for normalizing blood glucose level.
摘要:
The present invention is directed to identify genes involved in the growth of a plant and provide a transformed plant the growth of which is promoted utilizing the genes.
摘要:
An apparatus (14-1, 50) for encrypting image data is disclosed, which includes: a processor (42) configured to divide encoded still image data or video data into a first element (a) and a second element (b); generate a first key (k1); generate a second key (k2) for at least every one image of the still image data or video data; encrypt a first portion (b1) of the second element (b) of the image using the first key (k1) and the second key (k2) corresponding to the at least one image; replace a second portion (b2) of the second element (b) of the at least one image other than the first portion (b1) with the second key (k2) corresponding to the image; and compose the first element (a) of the image, the encrypted first portion (b1′) of the second element (b), and the second key (k2), for at least every one image to generate encrypted data. An apparatus (16-2, 17-2, 70) for decrypting which decrypts the encrypted data generated by the encryption apparatus is also disclosed.
摘要:
In a seat, in a state in which tilting of a back main frame around a tilting center is locked by a reclining mechanism, a lower end of a back joint link is turnably joined to a vehicle side. Thus, turning of a first link, a back sub frame and the back joint link is locked, and operation of a back link mechanism is locked. Therefore, a supporting rigidity from rear side of a back side portion can be enhanced by the back link mechanism (the back sub frame), and a crew sitting in the seat can be thoroughly retained.
摘要:
An object of the present invention is to provide a pancreatic islet transplantation technique that enables increase of graft survival rate of pancreatic islets after pancreatic islet transplantation, to maintain survival of pancreatic islets, and to reduce the number of transplanted pancreatic islets required for normalizing blood glucose level. When performing pancreatic islet transplantation, by transplanting pancreatic islets and adipose tissue-derived stem cells together, it is possible to significantly improve graft survival rate of transplanted pancreatic islets, and reduce by half the number of transplanted pancreatic islets required for normalizing blood glucose level.
摘要:
A multi-cylinder engine with a crankcase integrated cylinder block including a cylinder block having a plurality of cylinder bores, a plurality of crank chambers formed by an upper crankcase and a lower crankcase, a bulkhead that partitions between the cylinder bores and the crank chambers, and a honing release portion having a cylindrical honing release surface formed continuously with the cylinder bore in the upper crankcase and the bulkhead. The honing release surface forms an arcuate recessed portion in the bulkhead, the bulkhead is formed with a communication hole that includes a first opening edge on a side of the cylinder bore, a second opening edge on a side of the crank chamber having an opening width decreasing with a distance from the cylinder bore, and a third opening edge that extends substantially in parallel with the cylinder axis.
摘要:
Power is supplied to an ECU (20) from an on-vehicle battery (41). When an ignition switch (42) is switched from the OFF state to the ON state upon vehicle engine start, the ECU (20) is switched from the power saving mode to the normal mode and a CPU (31) executes initial processing. Moreover, when a user puts on a seat belt and a seat belt switch (44) is switched from the ON state to the OFF state, the ECU (20) is switched from the power saving mode to the normal mode and the CPU (31) executes the initial processing. Thus, the initial processing is executed at a comparatively short interval and it is possible to improve the reliability of the CPU (31).