- 专利标题： RNA sequence having anti-tumour activity
-
申请号： US15123623申请日： 2015-03-04
-
公开(公告)号： US10150966B2公开(公告)日： 2018-12-11
- 发明人: Hirofumi Yamamoto , Masaki Mori , Yuichiro Doki
- 申请人： Hirofumi Yamamoto , Masaki Mori
- 申请人地址： JP Suita-shi, Osaka JP Suita-shi, Osaka
- 专利权人： Hirofumi Yamamoto,Masaki Mori
- 当前专利权人： Hirofumi Yamamoto,Masaki Mori
- 当前专利权人地址： JP Suita-shi, Osaka JP Suita-shi, Osaka
- 代理机构： Knobbe, Martens, Olson & Bear, LLP
- 优先权： JP2014-041769 20140304
- 国际申请： PCT/JP2015/056352 WO 20150304
- 国际公布： WO2015/133521 WO 20150911
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; A61K47/02 ; A61K9/00 ; A61K9/51
摘要：
Provided is a novel useful microRNA having improved anti-tumor activity, obtained by introducing a variation in a microRNA which is present in-vivo and which exhibits an anti-tumor effect. This microRNA containing a base sequence (SEQ ID NO: 1) obtained by varying a predetermined region of the base sequence of miR-29b is able to exhibit a particularly outstanding anti-tumor effect.
公开/授权文献
- US20170073675A1 NOVEL RNA SEQUENCE HAVING ANTI-TUMOUR ACTIVITY 公开/授权日：2017-03-16
信息查询
