公开(公告)号：US4197166A

公开(公告)日：1980-04-08

申请号：US928964

申请日：1978-07-28

Applicant: Shigeo Inoue ,  Yoshiharu Kimura ,  Manzo Kinta

Inventor： Shigeo Inoue ,  Yoshiharu Kimura ,  Manzo Kinta

IPC: B01F17/56 ,  C07H3/04 ,  C07H15/10 ,  C12P19/44 ,  C12P19/46 ,  C12R1/88 ,  B01D3/34

CPC classification number: C07H15/10 ,  C07H3/04 ,  C12P19/44 ,  C12R1/88 ,  Y10S435/803 ,  Y10S435/944

Abstract: A dehydrating purification process for a fermentation product, which comprises adding at least one polyhydric alcohol represented by the formulae (III) or (IV), ##STR1## wherein R.sub.8 represents a hydrogen atom or a methyl group, R.sub.9 represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, and m and n represent integers from 1 to 6, to hydrated Sophorolipid or a secondary derivative thereof which is a fermentation product of Torulopsis bombicola, and distilling off water with heating under reduced pressure.

Abstract translation: 一种用于发酵产物的脱水纯化方法，其包括加入至少一种由式（III）或（IV）表示的多元醇，其中R 8表示氢原子或 甲基，R9表示氢原子或碳原子数1〜5的烷基，m和n表示1〜6的整数，作为Torulopsis bombicola的发酵产物的水合的槐糖脂或其二次衍生物，蒸馏除去 水在减压下加热。

公开(公告)号：US4216311A

公开(公告)日：1980-08-05

申请号：US961555

申请日：1978-11-17

Applicant: Shigeo Inoue ,  Yoshiharu Kimura ,  Manzo Kinta

Inventor： Shigeo Inoue ,  Yoshiharu Kimura ,  Manzo Kinta

IPC: C07H15/08 ,  A61K8/60 ,  B01F17/00 ,  B01F17/56 ,  C07H15/04 ,  C11B5/00 ,  C11D3/22 ,  C07H15/06 ,  C07H3/04

CPC classification number: C11D1/662 ,  C07H15/04

Abstract: A glycolipid methyl ester represented by the formula (I), ##STR1## wherein R.sub.3 represents a hydrogen atom or a methyl group, and R.sub.4 represents a saturated or unsaturated hydrocarbon group having 12 to 16 carbon atoms when R.sub.3 is a hydrogen atom, and R.sub.4 represents a saturated or unsaturated hydrocarbon group having 11 to 15 carbon atoms when R.sub.3 is a methyl group, is produced by adding at least one polyhydric alcohol represented by the formula (III) or (IV), ##STR2## wherein R.sub.5 represents a hydrogen atom or a methyl group, R.sub.6 and R.sub.7 represent a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, and m and n represent integers from 1 to 6, to hydrated Sophorolipid, removing water by distillation under reduced pressure, and subjecting the resulting Sophorolipid-polyhydric alcohol system to methanolysis and methylation by reaction with methanol in the presence of a strong acid.

Abstract translation: 由式（I）代表的糖脂甲酯，其中R 3表示氢原子或甲基，R 4表示当R 3为氢原子时具有12至16个碳原子的饱和或不饱和烃基 （III）或（IV）表示的至少一种多元醇，R4表示R3为甲基时碳原子数11〜15的饱和或不饱和烃基， （IV）其中R5表示氢原子或甲基，R6和R7表示氢原子或碳原子数为1〜5的烷基，m和n表示1〜6的整数，水合的槐糖脂， 通过减压蒸馏除去水，并且在强酸存在下，通过与甲醇反应，使所得的苦参多脂醇体系进行甲醇分解和甲基化。

公开(公告)号：US4215213A

公开(公告)日：1980-07-29

申请号：US962693

申请日：1978-11-21

Applicant: Shigeo Inoue ,  Yoshiharu Kimura ,  Manzo Kinta

Inventor： Shigeo Inoue ,  Yoshiharu Kimura ,  Manzo Kinta

IPC: A61K8/60 ,  B01F17/00 ,  B01F17/56 ,  C07H15/04 ,  C11B5/00 ,  C11D3/22 ,  C07H15/06 ,  C07H3/04

CPC classification number: C11D3/226 ,  C07H15/04

Abstract: A process for producing a glycolipid ester represented by the formula, ##STR1## wherein R.sub.3 represents a hydrogen atom or a methyl group, R.sub.4 represents a saturated or unsaturated hydrocarbon group having 12 to 16 carbon atoms when R.sub.3 is a hydrogen atom, R.sub.4 represents a saturated or unsaturated hydrocarbon group having 11 to 15 carbon atoms when R.sub.3 is a methyl group, and R represents a saturated or unsaturated alkyl group having 2 to 20 carbon atoms, which comprises subjecting Sophorolipid to methanolysis and methylation reactions by reaction with methanol in the presence of a strong acid to produce methyl 1-[(2'-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranosyl)oxy]-alkanoate and -alkenoate, and subjecting the resulting mixture to ester interchange by reaction with an alcohol represented by the formula,ROHwherein R is the same as defined above.

Abstract translation: 一种由式表示的糖脂酯的方法，其中R 3表示氢原子或甲基，R 4表示当R 3为氢原子时具有12至16个碳原子的饱和或不饱和烃基，R 4表示 R 3为甲基时为11〜15个碳原子的饱和或不饱和烃基，R为碳原子数为2〜20的饱和或不饱和的烷基，其包括在存在下通过与甲醇反应进行甲醇分解和甲基化反应 的强酸产生1 - [（2'-β-D-吡喃葡萄糖基-β-D-吡喃葡萄糖基）氧基] - 烷酸酯和 - 烯丙酸甲酯，并通过与所代表的醇反应将所得混合物进行酯交换 通式ROH其中R与上述定义相同。

公开(公告)号：US4195177A

公开(公告)日：1980-03-25

申请号：US962664

申请日：1978-11-21

Applicant: Shigeo Inoue ,  Yoshiharu Kimura ,  Manzo Kinta

Inventor： Shigeo Inoue ,  Yoshiharu Kimura ,  Manzo Kinta

IPC: B01F17/56 ,  A61K8/60 ,  A61K9/06 ,  A61K31/25 ,  C07H3/04 ,  C07H15/04 ,  C07H15/08 ,  C07H15/10 ,  C12P19/12 ,  C07H13/04

CPC classification number: A61K8/60 ,  A61Q19/00 ,  C07H15/10 ,  C07H3/04 ,  C12P19/12

Abstract: A hydroxyalkyl-etherified glycolipid ester represented by the formula (I), ##STR1## wherein R.sup.1 represents a methyl group or a hydrogen atom, R.sup.2 represents a saturated or unsaturated hydrocarbon group having 11 to 15 carbon atoms when R.sup.1 is a methyl group, R.sup.2 represents a saturated or unsaturated hydrocarbon group having 12 to 16 carbon atoms when R.sup.1 is a hydrogen atom, R.sup.3 represents a saturated or unsaturated hydrocarbon group having 1 to 20 carbon atoms, A represents --CH.sub.2 --CH.sub.2 --O-- or ##STR2## and a,b,c,d,e,f and g represent integers from 1 to 60 in the sum total.

Abstract translation: 由式（I）表示的羟烷基醚化糖脂酯，其中R1表示甲基或氢原子，R2表示当R1是甲基时，具有11至15个碳原子的饱和或不饱和烃基 基团，当R1是氢原子时，R2代表具有12-16个碳原子的饱和或不饱和烃基，R3代表具有1-20个碳原子的饱和或不饱和烃基，A代表-CH2-CH2-O-或和a，b，c，d，e，f和g表示总和中从1到60的整数。