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公开(公告)号：US08178057B2
公开(公告)日：2012-05-15
申请号：US12782201
申请日：2010-05-18
CPC分类号： G01N1/38 , B01L3/502715 , B01L3/50273 , B01L2200/027 , B01L2200/0605 , B01L2200/0684 , B01L2300/0654 , B01L2300/0825 , B01L2400/0406 , B01L2400/0475 , B01L2400/0478 , B01L2400/065 , B01L2400/0688 , Y10T436/25375 , Y10T436/2575
摘要： An apparatus for filling a sample volume defining device for separating at least one small defined volume of a liquid sample from a relatively larger undefined volume of said sample, said device including a first body and a second body movable relative to each other, whereby said first body has at least one cavity in a surface thereof, said at least one cavity having said defined volume. One of said first or said second body has at least one inlet opening adapted to be placed in a drop of the liquid sample. A defined channel is provided between said first and second body, which channel has fluid connection with said at least one opening and at least beyond said at least one cavity whereby the dimensions of said channel being such that said channel and said at least one cavity is filled with said liquid sample.
摘要翻译： 一种用于填充样品体积限定装置的设备，用于从相对较大的未定义体积的所述样品中分离出至少一个小的限定体积的液体样品，所述装置包括可相对于彼此移动的第一体和第二体， 主体在其表面中具有至少一个空腔，所述至少一个空腔具有所述限定的体积。 所述第一或所述第二主体中的一个具有适于放置在液体样品的液滴中的至少一个入口。 限定的通道设置在所述第一和第二主体之间，该通道与所述至少一个开口具有流体连接，并且至少超过所述至少一个空腔，由此所述通道的尺寸使得所述通道和所述至少一个空腔是 填充所述液体样品。
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公开(公告)号：US20080220464A1
公开(公告)日：2008-09-11
申请号：US12118603
申请日：2008-05-09
CPC分类号： G01N33/491 , B01L3/502 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L9/54 , B01L2200/027 , B01L2200/10 , B01L2300/0809 , B01L2300/0867 , B01L2400/0481 , B01L2400/0622 , B01L2400/065 , G01N1/38 , G01N33/4875
摘要： A blood test instrument using a disposable cartridge and a method of measuring a blood sample using the instrument are disclosed. The instrument includes a cell counting station for counting blood cells by electrical resistance measurement, a pressure actuating component adapted to apply a pressure alternately on two flexible receptacles of a disposable cartridge removably placed in the instrument to cause flowing of a mixture of a blood sample and a liquid agent between the two receptacles to obtain proper mixing, and a conduit adapted to deliver the mixture to the cell counting station for counting. After measuring the blood sample, the instrument withdraws a washing liquid contained in another receptacle of the disposable cartridge and uses the washing liquid to clean the instrument and to deliver the mixture back to the cartridge for disposal.
摘要翻译： 公开了一种使用一次性药筒的血液检查仪器和使用该仪器测量血液样品的方法。 该仪器包括用于通过电阻测量来计数血细胞的细胞计数站，压力致动部件，其适于在可拆卸地放置在仪器中的一次性药筒的两个柔性容器上交替施加压力，以引起血液样本和 两个容器之间的液体试剂以获得适当的混合，以及适于将混合物输送到细胞计数站进行计数的导管。 在测量血液样本之后，仪器将包含在一次性药筒的另一个容器中的洗涤液体取出并使用洗涤液清洁仪器并将混合物输送到药筒以进行处理。
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公开(公告)号：US07833746B2
公开(公告)日：2010-11-16
申请号：US12118603
申请日：2008-05-09
IPC分类号： C12Q1/02
CPC分类号： G01N33/491 , B01L3/502 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L9/54 , B01L2200/027 , B01L2200/10 , B01L2300/0809 , B01L2300/0867 , B01L2400/0481 , B01L2400/0622 , B01L2400/065 , G01N1/38 , G01N33/4875
摘要： A blood test instrument using a disposable cartridge and a method of measuring a blood sample using the instrument are disclosed. The instrument includes a cell counting station for counting blood cells by electrical resistance measurement, a pressure actuating component adapted to apply a pressure alternately on two flexible receptacles of a disposable cartridge removably placed in the instrument to cause flowing of a mixture of a blood sample and a liquid agent between the two receptacles to obtain proper mixing, and a conduit adapted to deliver the mixture to the cell counting station for counting. After measuring the blood sample, the instrument withdraws a washing liquid contained in another receptacle of the disposable cartridge and uses the washing liquid to clean the instrument and to deliver the mixture back to the cartridge for disposal.
摘要翻译： 公开了一种使用一次性药筒的血液检查仪器和使用该仪器测量血液样品的方法。 该仪器包括用于通过电阻测量来计数血细胞的细胞计数站，压力致动部件，其适于在可拆卸地放置在仪器中的一次性药筒的两个柔性容器上交替施加压力，以引起血液样本和 两个容器之间的液体试剂以获得适当的混合，以及适于将混合物输送到细胞计数站进行计数的导管。 在测量血液样本之后，仪器将包含在一次性药筒的另一个容器中的洗涤液体取出并使用洗涤液清洁仪器并将混合物输送到药筒以进行处理。
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公开(公告)号：US07608223B2
公开(公告)日：2009-10-27
申请号：US10533790
申请日：2003-11-19
IPC分类号： B01L3/00
CPC分类号： G01N33/491 , B01L3/502 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L9/54 , B01L2200/027 , B01L2200/10 , B01L2300/0809 , B01L2300/0867 , B01L2400/0481 , B01L2400/0622 , B01L2400/065 , G01N1/38 , G01N33/4875
摘要： A disposable apparatus for use in blood testing includes a housing (21) having integrated means (41) for receiving a blood sample, a plurality of receptacles (28-33) for diluent and diluted sample, and a plurality of channels (34-39). Depressions are formed in a surface (27) of the housing to form the receptacles (28-33) and the channels. A diaphragm (40) seals the receptacles and the channels relative to said surface (27). When a pressure variation is applied to a portion of the diaphragm sealing a receptacle, liquid is caused to be displaced to or from that receptacle.
摘要翻译： 用于血液测试的一次性装置包括具有用于接收血液样本的集成装置（41）的壳体（21），用于稀释剂和稀释样品的多个容器（28-33）和多个通道（34-39 ）。 凹陷形成在壳体的表面（27）中以形成插座（28-33）和通道。 隔膜（40）相对于所述表面（27）密封容器和通道。 当对膜片的一部分施加压力变化来密封容器时，液体被移动到或从该容器移位。
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公开(公告)号：US20060228263A1
公开(公告)日：2006-10-12
申请号：US11399423
申请日：2006-04-07
IPC分类号： B01L3/00
CPC分类号： G01N1/38 , B01L3/502715 , B01L3/50273 , B01L2200/027 , B01L2200/0605 , B01L2200/0684 , B01L2300/0654 , B01L2300/0825 , B01L2400/0406 , B01L2400/0475 , B01L2400/0478 , B01L2400/065 , B01L2400/0688 , Y10T436/25375 , Y10T436/2575
摘要： An apparatus for filling a sample volume defining device for separating at least one small defined volume of a liquid sample from a relatively larger undefined volume of said sample, said device including a first body and a second body movable relative to each other, whereby said first body has at least one cavity in a surface thereof, said at least one cavity having said defined volume. One of said first or said second body has at least one inlet opening adapted to be placed in a drop of the liquid sample. A defined channel is provided between said first and second body, which channel has fluid connection with said at least one opening and at least beyond said at least one cavity whereby the dimensions of said channel being such that said channel and said at least one cavity is filled with said liquid sample.
摘要翻译： 一种用于填充样品体积限定装置的设备，用于从相对较大的未定义体积的所述样品中分离出至少一个小的限定体积的液体样品，所述装置包括可相对于彼此移动的第一体和第二体， 主体在其表面中具有至少一个空腔，所述至少一个空腔具有所述限定的体积。 所述第一或所述第二主体中的一个具有适于放置在液体样品的液滴中的至少一个入口。 限定的通道设置在所述第一和第二主体之间，该通道与所述至少一个开口具有流体连接，并且至少超过所述至少一个空腔，由此所述通道的尺寸使得所述通道和所述至少一个空腔是 填充所述液体样品。
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6.发明授权Method of measuring blood sample on blood test instrument using a disposable cartridge 有权使用一次性药筒测量血液检测仪器上的血液样本的方法公开(公告)号：US08304207B2
公开(公告)日：2012-11-06
申请号：US12910097
申请日：2010-10-22
IPC分类号： C12Q1/02
CPC分类号： G01N33/491 , B01L3/502 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L9/54 , B01L2200/027 , B01L2200/10 , B01L2300/0809 , B01L2300/0867 , B01L2400/0481 , B01L2400/0622 , B01L2400/065 , G01N1/38 , G01N33/4875
摘要： A blood test instrument using a disposable cartridge and a method of measuring a blood sample using the instrument are disclosed. The instrument includes a cell counting station for counting blood cells by electrical resistance measurement, a pressure actuating component adapted to apply a pressure alternately on two flexible receptacles of a disposable cartridge removably placed in the instrument to cause flowing of a mixture of a blood sample and a liquid agent between the two receptacles to obtain proper mixing, and a conduit adapted to deliver the mixture to the cell counting station for counting. After measuring the blood sample, the instrument withdraws a washing liquid contained in another receptacle of the disposable cartridge and uses the washing liquid to clean the instrument and to deliver the mixture back to the cartridge for disposal.
摘要翻译： 公开了一种使用一次性药筒的血液检查仪器和使用该仪器测量血液样品的方法。 该仪器包括用于通过电阻测量来计数血细胞的细胞计数站，压力致动部件，其适于在可拆卸地放置在仪器中的一次性药筒的两个柔性容器上交替施加压力，以引起血液样本和 两个容器之间的液体试剂以获得适当的混合，以及适于将混合物输送到细胞计数站进行计数的导管。 在测量血液样本之后，仪器将包含在一次性药筒的另一个容器中的洗涤液体取出并使用洗涤液清洁仪器并将混合物输送到药筒以进行处理。
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公开(公告)号：US20100221150A1
公开(公告)日：2010-09-02
申请号：US12782201
申请日：2010-05-18
CPC分类号： G01N1/38 , B01L3/502715 , B01L3/50273 , B01L2200/027 , B01L2200/0605 , B01L2200/0684 , B01L2300/0654 , B01L2300/0825 , B01L2400/0406 , B01L2400/0475 , B01L2400/0478 , B01L2400/065 , B01L2400/0688 , Y10T436/25375 , Y10T436/2575
摘要： An apparatus for filling a sample volume defining device for separating at least one small defined volume of a liquid sample from a relatively larger undefined volume of said sample, said device including a first body and a second body movable relative to each other, whereby said first body has at least one cavity in a surface thereof, said at least one cavity having said defined volume. One of said first or said second body has at least one inlet opening adapted to be placed in a drop of the liquid sample. A defined channel is provided between said first and second body, which channel has fluid connection with said at least one opening and at least beyond said at least one cavity whereby the dimensions of said channel being such that said channel and said at least one cavity is filled with said liquid sample.
摘要翻译： 一种用于填充样品体积限定装置的设备，用于从相对较大的未定义体积的所述样品中分离出至少一个小的限定体积的液体样品，所述装置包括可相对于彼此移动的第一体和第二体， 主体在其表面中具有至少一个空腔，所述至少一个空腔具有所述限定的体积。 所述第一或所述第二主体中的一个具有适于放置在液体样品的液滴中的至少一个入口。 限定的通道设置在所述第一和第二主体之间，该通道与所述至少一个开口具有流体连接，并且至少超过所述至少一个空腔，由此所述通道的尺寸使得所述通道和所述至少一个空腔是 填充所述液体样品。
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8.发明申请METHOD OF MEASURING BLOOD SAMPLE ON BLOOD TEST INSTRUMENT USING A DISPOSABLE CARTRIDGE 有权使用可拆卸药盒测量血液测试仪器的血液样品的方法公开(公告)号：US20110039298A1
公开(公告)日：2011-02-17
申请号：US12910097
申请日：2010-10-22
CPC分类号： G01N33/491 , B01L3/502 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L9/54 , B01L2200/027 , B01L2200/10 , B01L2300/0809 , B01L2300/0867 , B01L2400/0481 , B01L2400/0622 , B01L2400/065 , G01N1/38 , G01N33/4875
摘要： A blood test instrument using a disposable cartridge and a method of measuring a blood sample using the instrument are disclosed. The instrument includes a cell counting station for counting blood cells by electrical resistance measurement, a pressure actuating component adapted to apply a pressure alternately on two flexible receptacles of a disposable cartridge removably placed in the instrument to cause flowing of a mixture of a blood sample and a liquid agent between the two receptacles to obtain proper mixing, and a conduit adapted to deliver the mixture to the cell counting station for counting. After measuring the blood sample, the instrument withdraws a washing liquid contained in another receptacle of the disposable cartridge and uses the washing liquid to clean the instrument and to deliver the mixture back to the cartridge for disposal.
摘要翻译： 公开了一种使用一次性药筒的血液检查仪器和使用该仪器测量血液样品的方法。 该仪器包括用于通过电阻测量来计数血细胞的细胞计数站，压力致动部件，其适于在可拆卸地放置在仪器中的一次性药筒的两个柔性容器上交替施加压力，以引起血液样本和 两个容器之间的液体试剂以获得适当的混合，以及适于将混合物输送到细胞计数站进行计数的导管。 在测量血液样本之后，仪器将包含在一次性药筒的另一个容器中的洗涤液体取出并使用洗涤液清洁仪器并将混合物输送到药筒以进行处理。
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公开(公告)号：US07744819B2
公开(公告)日：2010-06-29
申请号：US11399423
申请日：2006-04-07
CPC分类号： G01N1/38 , B01L3/502715 , B01L3/50273 , B01L2200/027 , B01L2200/0605 , B01L2200/0684 , B01L2300/0654 , B01L2300/0825 , B01L2400/0406 , B01L2400/0475 , B01L2400/0478 , B01L2400/065 , B01L2400/0688 , Y10T436/25375 , Y10T436/2575
摘要： An apparatus for filling a sample volume defining device for separating at least one small defined volume of a liquid sample from a relatively larger undefined volume of said sample, said device including a first body and a second body movable relative to each other, whereby said first body has at least one cavity in a surface thereof, said at least one cavity having said defined volume. One of said first or said second body has at least one inlet opening adapted to be placed in a drop of the liquid sample. A defined channel is provided between said first and second body, which channel has fluid connection with said at least one opening and at least beyond said at least one cavity whereby the dimensions of said channel being such that said channel and said at least one cavity is filled with said liquid sample.
摘要翻译： 一种用于填充样品体积限定装置的设备，用于从相对较大的未定义体积的所述样品中分离出至少一个小的限定体积的液体样品，所述装置包括可相对于彼此移动的第一体和第二体， 主体在其表面中具有至少一个空腔，所述至少一个空腔具有所述限定的体积。 所述第一或所述第二主体中的一个具有适于放置在液体样品的液滴中的至少一个入口。 限定的通道设置在所述第一和第二主体之间，该通道与所述至少一个开口具有流体连接，并且至少超过所述至少一个空腔，由此所述通道的尺寸使得所述通道和所述至少一个空腔是 填充所述液体样品。
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