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1.发明授权AZA compounds and production method thereof, and metal complexes as MRI contrast agents 有权AZA化合物及其制备方法，以及金属络合物作为MRI造影剂公开(公告)号：US08772475B2
公开(公告)日：2014-07-08
申请号：US12743777
申请日：2008-11-28
Applicant: Teruyuki Kondo , Hiroshi Tsujita , Zainul Abedin Siddique , Shingo Matsuki , Hiroki Miura , Hidehito Tochio , Tetsuya Matsuda , Michiko Narazaki , Hidetoshi Tsuzuki , Katsuaki Kuge , Yoshinori Tomida , Kimihiro Yoshimura , Tetsuya Yano
Inventor： Teruyuki Kondo , Hiroshi Tsujita , Zainul Abedin Siddique , Shingo Matsuki , Hiroki Miura , Hidehito Tochio , Tetsuya Matsuda , Michiko Narazaki , Hidetoshi Tsuzuki , Katsuaki Kuge , Yoshinori Tomida , Kimihiro Yoshimura , Tetsuya Yano
IPC: C07D225/00
CPC classification number: C07F5/003 , A61K49/106 , C07D255/02 , C07D257/02 , C07D259/00 , C07D405/14
Abstract: A core of a cyclic structure represented by (—N—(CH2)n—)k is bonded to a dendrimer-type side chain with a specific branched structure at all nitrogen atoms in the core to produce a compound with a specific structure for producing a metal complex that exhibits a T1-reducing effect, and the resulting compound is coordinated to a metal ion that has a T1-reducing effect to obtain a metal complex that exhibits an excellent T1-reducing effect which is useful as an effective component of an MRI contrast agent and an MRI contrast agent using the same.
Abstract translation: 由（-N-（CH 2）n - ）k表示的环状结构的核心与核心中所有氮原子上具有特定支化结构的树枝状大分子侧链结合，生成具有特定结构的化合物， 具有T1还原效果的金属络合物，所得化合物与具有T1还原效果的金属离子配位，得到显示出优异的T1还原效果的金属络合物，其可用作有机组分 MRI造影剂和使用其的MRI造影剂。
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2.发明申请公开(公告)号：US20140113225A1
公开(公告)日：2014-04-24
申请号：US14127672
申请日：2012-05-30
Applicant: Kimihiro Yoshimura , Yohei Miyauchi , Keiko Yamagishi , Kazuhisa Shirayama , Maho Hori
Inventor： Kimihiro Yoshimura , Yohei Miyauchi , Keiko Yamagishi , Kazuhisa Shirayama , Maho Hori
CPC classification number: G03G7/0053 , G03G5/14704 , G03G5/14734 , G03G5/14773 , G03G5/14795 , G03G15/162 , G03G2215/00957
Abstract: There are provided an electrophotographic photosensitive member and an intermediate transfer member each having good lubricity and good cleaning property on its surface, a process cartridge and an electrophotographic apparatus each including the electrophotographic photosensitive member, and an electrophotographic apparatus including the intermediate transfer member. Therefore, a surface layer of the electrophotographic photosensitive member or intermediate transfer member of the present invention contains a matrix component and a rotatably-retained spherical particle that is not bound with the matrix component and is rotatably retained in a pore in the matrix component.
Abstract translation: 提供了一种电子照相感光构件和中间转印构件，其各自在其表面上具有良好的润滑性和良好的清洁性，每个包括电子照相感光构件的处理盒和电子照相设备以及包括中间转印构件的电子照相设备。 因此，本发明的电子照相感光体或中间转印体的表面层含有不与基体成分结合的基体成分和可旋转保持的球状粒子，并可旋转地保持在基体成分的孔中。
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3.发明申请AZA COMPOUNDS AND PRODUCTION METHOD THEREOF, AND METAL COMPLEXES AS MRI CONTRAST AGENTS 有权AZA化合物及其生产方法，以及金属复合物作为对比剂公开(公告)号：US20110028713A1
公开(公告)日：2011-02-03
申请号：US12743777
申请日：2008-11-28
Applicant: Teruyuki Kondo , Hiroshi Tsujita , Zainul Abedin Siddique , Shingo Matsuki , Hiroki Miura , Hidehito Tochio , Tetsuya Matsuda , Michiko Narazaki , Hidetoshi Tsuzuki , Katsuaki Kuge , Yoshinori Tomida , Kimihiro Yoshimura , Tetsuya Yano
Inventor： Teruyuki Kondo , Hiroshi Tsujita , Zainul Abedin Siddique , Shingo Matsuki , Hiroki Miura , Hidehito Tochio , Tetsuya Matsuda , Michiko Narazaki , Hidetoshi Tsuzuki , Katsuaki Kuge , Yoshinori Tomida , Kimihiro Yoshimura , Tetsuya Yano
IPC: C07F5/00 , C07D405/14 , C07D407/12 , C07D255/02
CPC classification number: C07F5/003 , A61K49/106 , C07D255/02 , C07D257/02 , C07D259/00 , C07D405/14
Abstract: A core of a cyclic structure represented by (—N—(CH2)n—)k is bonded to a dendrimer-type side chain with a specific branched structure at all nitrogen atoms in the core to produce a compound with a specific structure for producing a metal complex that exhibits a T1-reducing effect, and the resulting compound is coordinated to a metal ion that has a T1-reducing effect to obtain a metal complex that exhibits an excellent T1-reducing effect which is useful as an effective component of an MRI contrast agent and an MRI contrast agent using the same.
Abstract translation: 由（-N-（CH 2）n - ）k表示的环状结构的核心与核心中所有氮原子上具有特定支化结构的树枝状大分子侧链结合，生成具有特定结构的化合物， 具有T1还原效果的金属络合物，所得化合物与具有T1还原效果的金属离子配位，得到显示出优异的T1还原效果的金属络合物，其可用作有机组分 MRI造影剂和使用其的MRI造影剂。
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4.发明授权公开(公告)号：US07829844B2
公开(公告)日：2010-11-09
申请号：US11775539
申请日：2007-07-10
Applicant: Hirokatsu Miyata , Kazuhiro Yamauchi , Kimihiro Yoshimura
Inventor： Hirokatsu Miyata , Kazuhiro Yamauchi , Kimihiro Yoshimura
CPC classification number: H01J49/0418
Abstract: A substrate for mass spectrometry for effectively performing ionization has been demanded. The substrate for mass spectrometry includes a base, a porous film formed on the base, and an inorganic material film formed on the porous film. The inorganic material film has a plurality of concaves formed vertically to the base, and the diameter of the concaves is not less than 1 nm and less than 1 μm.
Abstract translation: 已经要求用于有效地进行电离的质谱用基板。 用于质谱的基板包括基底，形成在基底上的多孔膜和形成在多孔膜上的无机材料膜。 无机材料膜具有与基底垂直形成的多个凹部，凹部的直径为1nm以上且1μm以下。
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公开(公告)号：US20100225314A1
公开(公告)日：2010-09-09
申请号：US12676239
申请日：2008-09-08
Applicant: Katsuaki Kuge , Kimihiro Yoshimura , Fumio Yamauchi , Tetsuya Yano , Masahiro Shirakawa , Yasuhiro Aoyama
Inventor： Katsuaki Kuge , Kimihiro Yoshimura , Fumio Yamauchi , Tetsuya Yano , Masahiro Shirakawa , Yasuhiro Aoyama
IPC: G01R33/44
CPC classification number: G01R33/485 , G01R33/4608 , G01R33/4633 , G01R33/4833 , G01R33/5605 , G01R33/5607
Abstract: The present invention provides a method for measuring nuclear magnetic resonance that employs a compound in which a plurality of nuclei is labeled with isotopes as a probe agent, highly selectively and highly sensitively obtains a nuclear magnetic resonance signal of the above described probe agent, and can attach a spatial positional information to the above described nuclear magnetic resonance signal, and an apparatus therefore.
Abstract translation: 本发明提供一种测定核磁共振的方法，其使用多个核被同位素标记的化合物作为探针剂，高度选择性且高度灵敏地获得上述探针剂的核磁共振信号，并且可以 将空间位置信息附加到上述核磁共振信号，因此装置。
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Patent Agency Ranking
公开(公告)号：US07700914B2
公开(公告)日：2010-04-20
申请号：US12133654
申请日：2008-06-05
Applicant: Kimihiro Yoshimura , Kazuya Miyazaki , Kazuhiro Yamada
Inventor： Kimihiro Yoshimura , Kazuya Miyazaki , Kazuhiro Yamada
CPC classification number: H01J49/0418
Abstract: Provided is a substrate for mass spectrometry, which enables a detection of a high molecular weight compound to be conducted at a high sensitivity, and can avoid the fragmentation so that there is substantially no obstacle to the analysis of a low molecular weight region. The substrate is a substrate for mass spectrometry for use in laser desorption/ionization mass spectrometry, containing a metal and having a porous structure on a surface thereof, wherein at least one functional group selected from the group consisting of a carboxyl group, a sulfonic group and an ammonium chloride group is covalently bonded to the surface of the substrate.
Abstract translation: 提供了一种用于质谱的基质，其能够以高灵敏度检测高分子量化合物，并且可以避免片段化，从而基本上不存在低分子量区域的分析的障碍。 基板是用于激光解吸/电离质谱的质谱用基板，含有金属，在其表面具有多孔结构，其中，选自羧基，磺酸基中的至少一种官能团 并且氯化铵基团共价结合到基材的表面。
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7.发明申请SUBSTRATE FOR MASS SPECTROMETRY, AND METHOD FOR MANUFACTURING SUBSTRATE FOR MASS SPECTROMETRY 有权用于质谱分析的基板，以及用于制造用于质谱分析的基板的方法公开(公告)号：US20080135781A1
公开(公告)日：2008-06-12
申请号：US11775539
申请日：2007-07-10
Applicant: Hirokatsu Miyata , Kazuhiro Yamauchi , Kimihiro Yoshimura
Inventor： Hirokatsu Miyata , Kazuhiro Yamauchi , Kimihiro Yoshimura
IPC: B01D59/44
CPC classification number: H01J49/0418
Abstract: A substrate for mass spectrometry for effectively performing ionization has been demanded. The substrate for mass spectrometry includes a base, a porous film formed on the base, and an inorganic material film formed on the porous film. The inorganic material film has a plurality of concaves formed vertically to the base, and the diameter of the concaves is not less than 1 nm and less than 1 μm.
Abstract translation: 已经要求用于有效地进行电离的质谱用基板。 用于质谱的基板包括基底，形成在基底上的多孔膜和形成在多孔膜上的无机材料膜。 无机材料膜具有垂直于基底形成的多个凹部，凹部的直径不小于1nm且小于1um。
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8.发明申请公开(公告)号：US20070111121A1
公开(公告)日：2007-05-17
申请号：US11617347
申请日：2006-12-28
Applicant: TOSHIHIRO KIKUCHI , ATSUSHI OCHI , HARUMI SAKO , KIMIHIRO YOSHIMURA , HIDEAKI TAMAI , NOBUO KOSAKA
Inventor： TOSHIHIRO KIKUCHI , ATSUSHI OCHI , HARUMI SAKO , KIMIHIRO YOSHIMURA , HIDEAKI TAMAI , NOBUO KOSAKA
IPC: G03G5/047
CPC classification number: G03G5/14786 , G03G5/0614 , G03G5/071 , G03G5/14717
Abstract: An electrophotographic photosensitive member, a process cartridge and an electrophotographic apparatus are provided which not only secure mechanical strength sufficiently but also bring a vast improvement in charge transport performance and which can well satisfy electrical properties. An electrophotographic photosensitive member is provided an outermost surface layer of which contains at least a charge transporting compound having chain polymerizable functional groups which is represented by the following general formula (1-1) or (1-2); the charge transporting compound having been polymerized or cross-linked and cured. Also provided are a process cartridge and an electrophotographic apparatus which have such a photosensitive member.
Abstract translation: 提供了一种电子照相感光构件，处理盒和电子照相设备，其不仅充分确保机械强度，而且还可以极大地改善电荷传输性能，并且可以很好地满足电性能。 提供电子照相感光构件，其最外表面层至少包含由以下通式（1-1）或（1-2）表示的具有链可聚合官能团的电荷输送化合物; 电荷输送化合物已经聚合或交联并固化。 还提供了具有这种感光构件的处理盒和电子照相设备。
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9.发明授权公开(公告)号：US06998210B2
公开(公告)日：2006-02-14
申请号：US10714948
申请日：2003-11-18
Applicant: Kimihiro Yoshimura , Yosuke Morikawa , Tatsuya Ikezue , Kouichi Nakata , Daisuke Tanaka
Inventor： Kimihiro Yoshimura , Yosuke Morikawa , Tatsuya Ikezue , Kouichi Nakata , Daisuke Tanaka
IPC: G03G5/147
CPC classification number: G03G5/1476
Abstract: The present invention relates to an electrophotographic photosensitive member comprising a surface layer excellent in adhesiveness and abrasion resistance, having a hardness and a toughness, and not degrading the charge transport property. One aspect of the present invention provides an electrophotographic photosensitive member comprising a photosensitive layer on a conductive support, wherein a surface layer of the photosensitive member contains a crosslinked epoxy-modified resol type phenolic resin, and at least one of a charge transport material and a conductive fine particle.
Abstract translation: 本发明涉及一种电子照相感光构件，其包括粘合性和耐磨性优异的表面层，具有硬度和韧性，并且不降低电荷传输性能。 本发明的一个方面提供一种电子照相感光构件，其在导电性载体上包含感光层，其中感光构件的表面层含有交联的环氧改性甲阶酚醛树脂型酚醛树脂，并且电荷输送材料和 导电细粒。
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10.发明申请公开(公告)号：US20140051018A1
公开(公告)日：2014-02-20
申请号：US14114157
申请日：2012-04-23
Applicant: Maho Hori , Kimihiro Yoshimura , Yohei Miyauchi , Kazuhisa Shirayama
Inventor： Maho Hori , Kimihiro Yoshimura , Yohei Miyauchi , Kazuhisa Shirayama
CPC classification number: G03G5/08 , G03G5/0507 , G03G5/0542 , G03G5/0564 , G03G5/0696 , G03G5/14704 , G03G5/14756
Abstract: The present invention relates to an electrophotographic photosensitive member including a support and a photosensitive layer formed on the support. The electrophotographic photosensitive member has a surface layer containing a polyarylate resin and acicular inorganic fillers. The acicular inorganic fillers are basic and have a number-average aspect ratio of 5 to 50 and a Mohs hardness of 2 to 6.
Abstract translation: 本发明涉及一种电子照相感光构件，其包括支撑体和形成在支撑体上的感光层。 电子照相感光构件具有包含多芳基化合物树脂和针状无机填料的表面层。 针状无机填料为碱性，数均分子量为5〜50，莫氏硬度为2〜6。
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