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公开(公告)号：US20100197889A1
公开(公告)日：2010-08-05
申请号：US12599960
申请日：2008-04-15
Applicant: Robert Beynon , Simon Gaskell , Julie Pratt , Claire Eyers
Inventor： Robert Beynon , Simon Gaskell , Julie Pratt , Claire Eyers
CPC classification number: G01N33/6851 , C07K5/1008 , C07K7/06 , C07K7/08 , C07K14/001 , G01N2458/15 , G01N2496/00
Abstract: The present invention provides a polypeptide as standard for peptide analysis by mass spectrometry comprising at least 16 peptides selected from the group consisting of the peptides of SEQ ID NO: 1 to SEQ ID NO: 22 or variants thereof, together with an artificial protein comprising the polypeptide, a vector comprising a nucleic acid encoding the polypeptide, a kit for proteome analysis, a selection of peptides for calibration an devaluation of mass spectrometers and chromatographs for proteome analyses and uses thereof.
Abstract translation: 本发明提供了通过质谱法进行肽分析的标准多肽，其包含至少16种选自SEQ ID NO：1至SEQ ID NO：22的肽或其变体的肽，以及包含 多肽，包含编码多肽的核酸的载体，用于蛋白质组分析的试剂盒，用于校准质谱仪的贬值的肽的选择和用于蛋白质组分析的色谱仪及其用途。
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公开(公告)号：US20080076709A1
公开(公告)日：2008-03-27
申请号：US11698250
申请日：2007-01-25
Applicant: Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
Inventor： Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
CPC classification number: C12N9/0036 , A61K38/00 , A61K39/00 , C07K14/31 , C07K16/1275 , C07K2319/00 , C12N9/78 , C12N15/52 , C12Q1/689 , C12Q2600/158 , C12Y105/0103 , C12Y305/04025
Abstract: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
Abstract translation: 本发明涉及新鉴定的葡萄球菌多核苷酸，由这种多核苷酸编码的多肽，这种多核苷酸和多肽的用途，以及这些多核苷酸和多肽的产生以及用多核苷酸转化的重组宿主细胞。 本发明还涉及抑制这些多核苷酸或多肽的生物合成或作用以及这种抑制剂在治疗中的用途。
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公开(公告)号：US08399402B2
公开(公告)日：2013-03-19
申请号：US12599960
申请日：2008-04-15
Applicant: Robert Beynon , Simon Gaskell , Julie Pratt , Claire Eyers
Inventor： Robert Beynon , Simon Gaskell , Julie Pratt , Claire Eyers
IPC: A61K38/00
CPC classification number: G01N33/6851 , C07K5/1008 , C07K7/06 , C07K7/08 , C07K14/001 , G01N2458/15 , G01N2496/00
Abstract: The present invention provides a polypeptide as standard for peptide analysis by mass spectrometry comprising at least 16 peptides selected from the group consisting of the peptides of SEQ ID NO: 1 to SEQ ID NO: 22 or variants thereof, together with an artificial protein comprising the polypeptide, a vector comprising a nucleic acid encoding the polypeptide, a kit for proteome analysis, a selection of peptides for calibration an devaluation of mass spectrometers and chromatographs for proteome analysis and uses thereof.
Abstract translation: 本发明提供了通过质谱法进行肽分析的标准多肽，其包含至少16种选自SEQ ID NO：1至SEQ ID NO：22的肽或其变体的肽，以及包含 多肽，包含编码多肽的核酸的载体，用于蛋白质组分析的试剂盒，用于校准质谱仪的贬值的肽的选择和用于蛋白质组分析的色谱仪及其用途。
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公开(公告)号：US20060083752A1
公开(公告)日：2006-04-20
申请号：US11166905
申请日：2005-06-23
Applicant: Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
Inventor： Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
IPC: A61K39/02 , C07H21/04 , C12N15/74 , C07K14/195 , C12N1/21
CPC classification number: C12N9/0036 , A61K38/00 , A61K39/00 , C07K14/31 , C07K16/1275 , C07K2319/00 , C12N9/78 , C12N15/52 , C12Q1/689 , C12Q2600/158 , C12Y105/0103 , C12Y305/04025
Abstract: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
Abstract translation: 本发明涉及新鉴定的葡萄球菌多核苷酸，由这种多核苷酸编码的多肽，这种多核苷酸和多肽的用途，以及这些多核苷酸和多肽的产生以及用多核苷酸转化的重组宿主细胞。 本发明还涉及抑制这些多核苷酸或多肽的生物合成或作用以及这种抑制剂在治疗中的用途。
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