公开(公告)号：US08652212B2

公开(公告)日：2014-02-18

申请号：US12362159

申请日：2009-01-29

申请人： Kirt L. Case ,  Oludele O. Popoola ,  Robby Kissling ,  Brion R. Mimnaugh ,  Archie W. Newsome ,  Clarence M. Panchison ,  Dirk L. Pletcher ,  Randy L. Schlemmer ,  Zhibin Fang ,  Juan Vivanco ,  Alicia Rufner

发明人： Kirt L. Case ,  Oludele O. Popoola ,  Robby Kissling ,  Brion R. Mimnaugh ,  Archie W. Newsome ,  Clarence M. Panchison ,  Dirk L. Pletcher ,  Randy L. Schlemmer ,  Zhibin Fang ,  Juan Vivanco ,  Alicia Rufner

IPC分类号： A61F2/32

CPC分类号： B29C70/682 ,  A61B17/86 ,  A61F2/30942 ,  A61F2/34 ,  A61F2002/30329 ,  A61F2002/305 ,  A61F2002/3092 ,  A61F2002/3096 ,  A61F2002/30981 ,  A61F2002/3291 ,  A61F2002/3401 ,  A61F2002/3411 ,  A61F2220/0025 ,  A61F2310/00131 ,  A61L27/18 ,  A61L27/50 ,  A61L27/56 ,  B29C43/18 ,  B29C45/14 ,  C08L71/00

摘要： An orthopedic component having multiple layers that are selected to provide an overall modulus that is substantially lower than the modulus of known orthopedic components to more closely approximate the modulus of the bone into which the orthopedic component is implanted. In one exemplary embodiment, the orthopedic component is an acetabular shell. For example, the acetabular shell may include an outer layer configured for securement to the natural acetabulum of a patient and an inner layer configured to receive an acetabular liner. The head of a femoral prosthesis articulates against the acetabular liner to replicate the function of a natural hip joint. Alternatively, the inner layer of the acetabular shell may act as an integral acetabular liner against which the head of the femoral prosthesis articulates.

摘要翻译： 具有多个层的整形外科组件被选择以提供基本上低于已知矫形部件的模量的总模量，以更接近地将骨骼部件植入其中的骨的模数近似近似。 在一个示例性实施例中，矫形部件是髋臼壳。 例如，髋臼壳可以包括被配置用于固定到患者的天然髋臼的外层和构造成接收髋臼衬垫的内层。 股骨假体的头部与髋臼衬垫铰接以复制天然髋关节的功能。 或者，髋臼壳的内层可以作为整体的髋臼衬垫，股骨假体的头与该髋臼衬垫铰接。

公开(公告)号：US20090192610A1

公开(公告)日：2009-07-30

申请号：US12362159

申请日：2009-01-29

申请人： Kirt L. Case ,  Oludele O. Popoola ,  Robby Kissling ,  Brion R. Mimnaugh ,  Archie W. Newsome ,  Clarence M. Panchison ,  Dirk L. Pletcher ,  Randy L. Schlemmer ,  Zhibin Fang ,  Juan Vivanco ,  Alicia Rufner

发明人： Kirt L. Case ,  Oludele O. Popoola ,  Robby Kissling ,  Brion R. Mimnaugh ,  Archie W. Newsome ,  Clarence M. Panchison ,  Dirk L. Pletcher ,  Randy L. Schlemmer ,  Zhibin Fang ,  Juan Vivanco ,  Alicia Rufner

IPC分类号： A61F2/28 ,  A61F2/32 ,  B29D31/505

CPC分类号： B29C70/682 ,  A61B17/86 ,  A61F2/30942 ,  A61F2/34 ,  A61F2002/30329 ,  A61F2002/305 ,  A61F2002/3092 ,  A61F2002/3096 ,  A61F2002/30981 ,  A61F2002/3291 ,  A61F2002/3401 ,  A61F2002/3411 ,  A61F2220/0025 ,  A61F2310/00131 ,  A61L27/18 ,  A61L27/50 ,  A61L27/56 ,  B29C43/18 ,  B29C45/14 ,  C08L71/00

摘要： An orthopedic component having multiple layers that are selected to provide an overall modulus that is substantially lower than the modulus of known orthopedic components to more closely approximate the modulus of the bone into which the orthopedic component is implanted. In one exemplary embodiment, the orthopedic component is an acetabular shell. For example, the acetabular shell may include an outer layer configured for securement to the natural acetabulum of a patient and an inner layer configured to receive an acetabular liner. The head of a femoral prosthesis articulates against the acetabular liner to replicate the function of a natural hip joint. Alternatively, the inner layer of the acetabular shell may act as an integral acetabular liner against which the head of the femoral prosthesis articulates.

摘要翻译： 具有多个层的整形外科组件被选择以提供基本上低于已知矫形部件的模量的总模量，以更接近地将骨骼部件植入其中的骨的模数近似近似。 在一个示例性实施例中，矫形部件是髋臼壳。 例如，髋臼壳可以包括被配置用于固定到患者的天然髋臼的外层和构造成接收髋臼衬垫的内层。 股骨假体的头部与髋臼衬垫铰接以复制天然髋关节的功能。 或者，髋臼壳的内层可以作为整体的髋臼衬垫，股骨假体的头与该髋臼衬垫铰接。

公开(公告)号：US20090112315A1

公开(公告)日：2009-04-30

申请号：US12259726

申请日：2008-10-28

申请人： Zhibin Fang ,  Yang W. Son ,  Juan Vivanco ,  Kai Zhang ,  Danny L. Levine

发明人： Zhibin Fang ,  Yang W. Son ,  Juan Vivanco ,  Kai Zhang ,  Danny L. Levine

IPC分类号： A61F2/02 ,  A61F2/28

CPC分类号： A61F2/30 ,  A61F2/30767 ,  A61F2/34 ,  A61F2/389 ,  A61F2002/30062 ,  A61F2002/30677 ,  A61F2002/3092 ,  A61F2002/30929 ,  A61F2002/30957 ,  A61F2210/0004 ,  A61F2310/00095 ,  A61F2310/00131 ,  A61F2310/00491 ,  A61F2310/00544 ,  A61F2310/00976 ,  A61L27/025 ,  A61L27/04 ,  A61L27/44 ,  A61L27/52 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/406 ,  A61L2300/414 ,  A61L2300/604 ,  A61L2300/61

摘要： Medical implants, such as orthopedic implants of the type used in partial or total joint replacement procedures, for example. The implants include a porous substrate, and a bearing portion of a polymeric material, for example, which is at least partially molded within the porous substrate. The bearing portion includes a bearing surface that is exposed to an articulating component of another medical implant, and the porous metal substrate contacts the bone for osseointegration of the bone tissue into the porous substrate to anchor the implant. The porous substrate may include biodegradable carrier materials, in the form of one or more layers, that carry biologically active agents such as antibiotics and bone growth factors, for example. The layers of biodegradable carrier materials may be tailored such that, after implantation of the implants, the biologically active agents are released sequentially and/or over time into the surrounding tissue to reduce the chances of infection and/or to promote osseointegration of the implant, for example.

摘要翻译： 医疗植入物，例如用于部分或全部关节置换手术的类型的矫形植入物。 植入物包括多孔基底和聚合物材料的支承部分，例如其至少部分地模制在多孔基底内。 轴承部分包括暴露于另一种医用植入物的关节部件的支承表面，并且多孔金属基底接触骨，用于将骨组织骨整合到多孔基质中以锚定植入物。 多孔基材可以包括例如具有携带生物活性剂如抗生素和骨生长因子的一层或多层形式的可生物降解的载体材料。 生物可降解载体材料的层可以被定制，使得在植入植入物之后，生物活性剂被顺序地和/或随时间释放到周围组织中以减少感染和/或促进植入物的骨整合的机会， 例如。