公开(公告)号：US20060002768A1

公开(公告)日：2006-01-05

申请号：US10879589

申请日：2004-06-30

申请人： John Meyer ,  John Meyer

发明人： John Meyer ,  John Meyer

IPC分类号： E02D5/00 ,  E21D5/00

CPC分类号： E02D17/04

摘要： A corner connection used to secure I-beams together at corners within the excavation site is provided with a reinforcing assembly that allows for greater loads. Typically, four I-beams are connected together to form a rectangular frame that is suspended within the excavation for bracing the shoring walls thereof, however, any polygonal shape may be used. The corner connection itself comprises mating socket or connecting members that are placed over the ends of I-beams to be fastened together. One of the connecting members includes an outwardly extended tab while the other includes a pair of outwardly extended tabs. The first outwardly extending tab fits between the two extending tabs of the corresponding connecting member. All of the tabs are provided with apertures that are placed in alignment when the connection is made so that a bolt or pin can be passed through the apertures to secure the two connectors together. An additional set of tabs is provided on the connecting members that is also provide with apertures. A reinforcing assembly is provided and includes a reinforcing bar with tabs. A first spacer bar is attached to the reinforcing bar and one connecting member and a second spacer bar is attached to the reinforcing bar and an adjacent connecting member. The spacer bars, the reinforcing bar and the connection members are all connected with tab/pin connections. Advantageously the reinforcing assembly can use the existing second set of tabs located on the prior art connectors. Such an arrangement provides much greater support for the sidewalls of the excavation site.

摘要翻译： 用于将I型梁固定在挖掘位置的拐角处的一个角连接件设有一个允许更大负载的加强组件。 通常，四个I型梁连接在一起以形成悬挂在挖掘中用于支撑其支撑壁的矩形框架，然而，可以使用任何多边形形状。 角连接本身包括配合插座或连接构件，其放置在将被紧固在一起的I型梁的端部上。 连接构件中的一个包括向外延伸的突出部，而另一个包括一对向外延伸的突出部。 第一向外延伸的突出部配合在相应连接件的两个伸出的突片之间。 所有的突出部都设置有孔，当连接被制成时，孔被放置成对齐，使得螺栓或销能够穿过孔以将两个连接器固定在一起。 在连接构件上还设有另外一组突出部，其还具有孔。 提供加强组件并且包括具有突出部的钢筋。 第一间隔杆连接到钢筋上，一个连接构件和第二间隔杆连接到钢筋和相邻的连接构件。 间隔杆，钢筋和连接构件均与接头/销连接。 有利地，加强组件可以使用位于现有技术连接器上的现有第二组突片。 这种布置为挖掘现场的侧壁提供了更大的支撑。

公开(公告)号：US09510055B2

公开(公告)日：2016-11-29

申请号：US13748357

申请日：2013-01-23

申请人： Ron Kuper ,  Arthur L. Coburn, IV ,  John Meyer ,  Mike Delaney

发明人： Ron Kuper ,  Arthur L. Coburn, IV ,  John Meyer ,  Mike Delaney

IPC分类号： H04N21/4788 ,  H04N21/436 ,  H04N21/482 ,  G11B27/10 ,  G11B27/34

CPC分类号： H04N21/4788 ,  G06F3/0482 ,  G06F3/04847 ,  G11B27/105 ,  G11B27/34 ,  H04L41/22 ,  H04L67/10 ,  H04N21/43615 ,  H04N21/4825

摘要： Embodiments described herein include systems and methods for providing a social interface for sharing media experience information between households in a community. Users of different households may form the community. The social interface may be provided as an application on a mobile device or an Internet webpage as a portal to the community. The social interface may display a list of households, and a user of the interface may select a household from the list to view information on media being experienced within the household. The selected household may include separate groups of media players configured to render media in synchrony, and the social interface may display, upon selection of the household, a list of the separate groups included in the selected household. The user may then select a group from the list, among other actions, view information on media being rendered by the media players in the selected group.

摘要翻译： 本文描述的实施例包括用于提供用于在社区中的家庭之间共享媒体体验信息的社交界面的系统和方法。 不同家庭的用户可能形成社区。 社交界面可以作为移动设备或互联网网页上的应用程序提供给社区的门户。 社交界面可以显示家庭列表，并且接口的用户可以从列表中选择一个家庭来查看关于家庭内经历的媒体的信息。 所选择的家庭可以包括被配置为同步呈现媒体的单独媒体播放器组，并且社交界面可以在选择家庭时显示包括在所选择的家庭中的单独组的列表。 然后，用户可以从列表中选择一个组，以及其他动作，查看由所选择的组中的媒体播放器呈现的媒体的信息。

公开(公告)号：US20160046711A1

公开(公告)日：2016-02-18

申请号：US14820897

申请日：2015-08-07

申请人： Carl Uli BIALUCHA ,  Scott COLLINS ,  Clemens DÜRR ,  Tiancen HU ,  Mary Jo JANATPOUR ,  Matthew John MEYER

发明人： Carl Uli BIALUCHA ,  Scott COLLINS ,  Clemens DÜRR ,  Tiancen HU ,  Mary Jo JANATPOUR ,  Matthew John MEYER

IPC分类号： C07K16/28 ,  A61K47/48 ,  A61K45/06 ,  G01N33/574

CPC分类号： C07K16/28 ,  A61K31/4738 ,  A61K45/06 ,  A61K47/6803 ,  A61K47/6849 ,  A61K47/6889 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/34 ,  C07K2317/40 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/73 ,  C07K2317/92 ,  G01N33/57492 ,  G01N2333/705 ,  A61K2300/00 ,  A61K39/395

摘要： The present invention relates to anti-CDH6 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.

摘要翻译： 本发明涉及抗CDH6抗体，抗体片段，抗体药物偶联物及其用于治疗癌症的用途。

公开(公告)号：US20100021966A1

公开(公告)日：2010-01-28

申请号：US12405857

申请日：2009-03-17

申请人： Anurag Rathore ,  Stephen B. Lyle ,  David E. Steinmeyer ,  Scott I. Allen ,  John Meyer ,  Denis M. Boyle ,  John J. Buckley ,  Gary V. Johnson

发明人： Anurag Rathore ,  Stephen B. Lyle ,  David E. Steinmeyer ,  Scott I. Allen ,  John Meyer ,  Denis M. Boyle ,  John J. Buckley ,  Gary V. Johnson

IPC分类号： C12N15/09

CPC分类号： C07K1/18 ,  C07K14/61

摘要： The present invention is directed generally to recombinant methods for making a desired polypeptide. These method(s) yield a polypeptide product containing reduced levels of isoform impurities thereof. In particular, the present invention is directed to (1) a recombinant method for preparing growth hormone with reduced isoform impurities thereof and (2) a recombinant method for preparing a growth hormone antagonist, such as pegvisomant, and its protein intermediate, also having reduced isoform impurities thereof. More specifically, the isoform impurities that are decreased by methods of the present invention are the trisulfide and des-phe isoform impurities of growth hormone and growth hormone antagonist (or its intermediate), respectively.

摘要翻译： 本发明一般涉及制备所需多肽的重组方法。 这些方法产生含有降低水平的异构体杂质的多肽产物。 特别地，本发明涉及（1）一种用于制备具有降低的同种型杂质的生长激素的重组方法和（2）一种用于制备生长激素拮抗剂的重组方法，所述生长激素拮抗剂例如栓塞坦及其蛋白质中间体， 其异构体杂质。 更具体地，通过本发明的方法减少的同种型杂质分别是生长激素和生长激素拮抗剂（或其中间体）的三硫化物和脱氢异构体杂质。

公开(公告)号：US07064619B1

公开(公告)日：2006-06-20

申请号：US11142086

申请日：2005-05-31

申请人： Charles John Meyer ,  Donald A. Palaski

发明人： Charles John Meyer ,  Donald A. Palaski

IPC分类号： G01R23/00

CPC分类号： G04G3/02 ,  G04R40/06

摘要： A method and apparatus for restarting a GPS-based timing system without a GPS signal is provided. More specifically, there is provided a system comprising an antenna, a GPS receiver coupled to the antenna and configured to generate a GPS traceable timing signal based on a GPS transmission, and a timing system coupled to the GPS receiver, the timing system comprising a holdover oscillator, timing circuitry coupled to the holdover oscillator and configured to receive the GPS traceable timing signal and to calculate a correction factor for the holdover oscillator, and a non-volatile memory coupled to the timing circuitry, wherein the timing circuitry is configured to store the correction factor on the non-volatile memory.

摘要翻译： 提供一种用于重新启动没有GPS信号的基于GPS的定时系统的方法和装置。 更具体地，提供了一种系统，包括天线，耦合到天线的GPS接收器，并且被配置为基于GPS传输产生GPS可跟踪定时信号，以及与GPS接收器耦合的定时系统，该定时系统包括保持 振荡器，定时电路，其耦合到所述保持振荡器并且被配置为接收所述GPS可跟踪定时信号并且计算所述保持振荡器的校正因子，以及耦合到所述定时电路的非易失性存储器，其中所述定时电路被配置为存储 非易失性存储器的校正因子。

公开(公告)号：US06935256B1

公开(公告)日：2005-08-30

申请号：US10839745

申请日：2004-05-05

申请人： Bradley John Meyer

发明人： Bradley John Meyer

IPC分类号： A01C7/08 ,  A01C7/10 ,  A01C1/00 ,  A01C7/00

CPC分类号： A01C7/105 ,  A01C7/081

摘要： A control system selectively operates an agitator within a main hopper or bulk tank for a product-on-demand delivery system. A differential pressure switch is used to control operation of the agitator. The differential pressure switch measures the pressure difference between the pressurized air pressure upstream of the tank and tank air pressure to determine when the system is not delivering adequate product to the application units, based on the high air flow rate in the system. When the sensor signals that the system is not delivering adequate product, the system automatically starts the agitator, and conversely when the sensor signals that the system is delivering adequate product, the system automatically stops the agitator.

摘要翻译： 控制系统选择性地操作用于产品点播递送系统的主料斗或散装罐内的搅拌器。 差压开关用于控制搅拌器的运行。 差压开关测量罐体上游加压空气压力与油箱空气压力之间的压力差，以确定系统何时基于系统中的高空气流量向应用单元输送足够的产品。 当传感器发出指示系统没有交付足够的产品时，系统会自动启动搅拌器，反之，当传感器发出指示系统提供足够的产品时，系统会自动停止搅拌器。

公开(公告)号：US20050146217A1

公开(公告)日：2005-07-07

申请号：US10745884

申请日：2003-12-26

申请人： John Meyer

发明人： John Meyer

IPC分类号： B60R25/00 ,  G08B13/06 ,  G08B13/12

CPC分类号： G08B13/126 ,  B60R25/016 ,  G08B13/06

摘要： A security bar providing improved security from breach is obtained with the use of a plurality of free rolling inner bars. Illustratively, three inner rolling bars, arranged in a triangular relationship, are provided inside a cylindrically hollowed out outer bar, thereby ensuring that no inner bar can be attacked simultaneously from opposing sides thereof. The inner bars may be surrounded with a ring of ball bearings to provide for their ability to roll freely in place with respect to the outer bar. Electronic monitoring of the security bar identifies attempts to breach the security bar.

摘要翻译： 通过使用多个自由滚动的内部杆来获得提供改进的破裂安全性的安全杆。 示例性地，在圆柱形中空的外部杆中设置三个关系的三个内滚动条，从而确保没有内杆可以从其相对侧同时受到攻击。 内杆可以被一个滚珠轴承圈包围，以提供它们相对于外杆自由滚动的能力。 安全栏的电子监控标识了违反安全条的尝试。

公开(公告)号：US20050117765A1

公开(公告)日：2005-06-02

申请号：US10992040

申请日：2004-11-18

申请人： John Meyer ,  Andrew Morabito

发明人： John Meyer ,  Andrew Morabito

IPC分类号： H04R25/00

CPC分类号： H04R25/658 ,  B33Y70/00 ,  B33Y80/00 ,  H04R25/652

摘要： Disclosed is a hearing aid assembly wherein the hearing aid is comprised of an acoustic receiver, an acoustic transmitter, and a body, and an annular channel, wherein the acoustic receiver is designed to fit into a external acoustic meatus of an ear, the acoustic transmitter is designed to fit into a inner ear canal, and the generally cylindrical body is disposed between the receiver and the transmitter, the annular channel is disposed on the surface of the body such that it circumscribes the body's circumference. The annular channel is adapted to receive an annular ring which functions as an acoustic seal.

摘要翻译： 公开了一种助听器组件，其中助听器由声学接收器，声发射器和身体以及环形通道组成，其中声学接收器被设计成适合于耳朵的外部声学通道，声发射器 设计成适合于内耳道，并且大致圆柱体设置在接收器和发射器之间，环形通道设置在身体的表面上，使得其环绕身体的周长。 环形通道适于接收用作声学密封的环形环。

公开(公告)号：US20050030554A1

公开(公告)日：2005-02-10

申请号：US10638698

申请日：2003-08-09

申请人： Bradford Dixon ,  John Meyer ,  David Towery

发明人： Bradford Dixon ,  John Meyer ,  David Towery

IPC分类号： B41J29/02 ,  B41J29/38 ,  B41J29/393 ,  B41J1/00

CPC分类号： B41J29/38 ,  B41J29/02

摘要： An embodiment of a printing apparatus is provided as including a chassis, a print engine supported by the chassis, and a casing of a cardboard material comprising cellulose fiber attached to the chassis and surrounding the print engine when attached to the chassis. A business method for recycling or refurbishing a recyclable printing mechanism is also provided.

摘要翻译： 打印装置的一个实施例被提供为包括底盘，由底盘支撑的打印引擎，以及包含纤维素纤维的纸板材料的壳体，该纤维素纤维附接到底盘并且当连接到底盘时围绕打印引擎。 还提供了回收或翻新可回收打印机构的商业方法。

公开(公告)号：USRE38172E1

公开(公告)日：2003-07-08

申请号：US09741784

申请日：2000-12-20

申请人： Daniell Revenaugh ,  John Meyer

发明人： Daniell Revenaugh ,  John Meyer

IPC分类号： G10C302

CPC分类号： G10C3/02

摘要： A grand piano having a lower lid attached thereto by hinges, and a lid designed for attachment to the bottom of a grand piano. The lid completely covers the bottom of the piano case when latched in a closed position. In its closed position, the lower lid protects the soundboard from damage (such as during transportation of the piano) and mutes the piano's sound. The lower lid of the invention is designed so that, when released from its closed position and pivoted downward into an open position, it will reflect sound from the soundboard outward from the front of the piano. Preferably, the angular orientation of the lower lid in its open position is chosen to reinforce and focus the projection of sound within a desired frequency range (for example, midrange sounds) to a desired target region. Such optimal angular orientation can be determined experimentally. In one embodiment, the lower lid consists of two or more panels connected together by hinges, so that it can be detached from the piano and folded into a compact volume for convenient handling and storage. The dimensions of the lid and the positions of hinges which connect its panels are preferably predetermined so that lid has an optimal orientation for reinforcing projection of midrange sounds (or sounds within another desired frequency range) in a typically-sized room or concert hall when the lid is lowered to an open position in which it rests on the floor.

摘要翻译： 具有通过铰链附接到其上的下盖的大钢琴和设计用于附接到大钢琴底部的盖子。 当锁定在关闭位置时，盖子完全覆盖钢琴盒的底部。 在其关闭位置，下盖可保护音板免受损坏（例如在钢琴运输过程中），并使钢琴的声音静音。 本发明的下盖被设计成当从其关闭位置释放并向下枢转到打开位置时，它将从钢琴的前部向外反射来自声板的声音。 优选地，下盖在其打开位置的角度定向被选择为将声音的投影强化并聚焦在期望的频率范围（例如，中音）内到期望的目标区域。 这种最佳角度取向可以通过实验确定。 在一个实施例中，下盖由通过铰链连接在一起的两个或更多个面板组成，使得其可以从钢琴上拆下并折叠成紧凑的体积以便于操作和储存。 优选地，盖的尺寸和连接其面板的铰链的位置是预定的，使得盖具有用于在典型尺寸的房间或音乐厅中加强对中音（或另一所需频率范围内的声音）的投影的最佳取向， 盖子下降到打开位置，在该打开位置，它放在地板上。