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公开(公告)号：US11704792B2
公开(公告)日：2023-07-18
申请号：US16645872
申请日：2018-09-24
发明人： Timor Kadir , Lyndsey Pickup , Vaclav Potesil , Jerome Declerck
CPC分类号： G06T7/0012 , G16H30/40 , G16H50/20 , G16H50/30 , G16H50/70 , G06T2207/10081 , G06T2207/10104 , G06T2207/20081 , G06T2207/20084 , G06T2207/30064
摘要： A Computer Aided Diagnosis, CADx, system (200) is described that comprises: at least one input (210, 212, 214) configured to provide at least one input medical image; and a CADx processing engine (220) configured to receive and process the at least one input medical image and produce at least one CADx score. A CADx score mapping circuit is operably coupled to the CADx processing engine (220) and configured to: map the at least one CADx score to a risk adjusted virtual score; and generate an output (235) of at least the risk adjusted virtual score associated with the processed at least one input medical image. The at least one CADx score and the risk adjusted virtual score correspond to an equivalent risk of condition or disease associated with a patient.
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公开(公告)号：US08693741B2
公开(公告)日：2014-04-08
申请号：US12575653
申请日：2009-10-08
CPC分类号： A61B6/12 , A61B5/20 , A61B5/201 , A61B5/7239 , A61B6/037 , G01T1/00 , G06F19/00 , G06T7/0016 , G06T2207/10104 , G06T2207/30084
摘要： In a method and apparatus for analyzing medical imaging data of a subject from an imaging modality using a tracer, data from detection of tracer emission events at least one region of a scanned imaging volume are obtained, and the data processed to establish sub-periods or time points within a scan period for the emission events. A rate of change of emission events per unit time for a given region is then calculated, for example by obtaining a number of emission events in each sub-period in the given region, and fitting a line through the values for the sub-periods.
摘要翻译： 在使用示踪剂从成像模态分析被检体的医学成像数据的方法和装置中，获得来自扫描成像体积的至少一个区域的示踪剂发射事件的检测的数据，并且处理数据以建立子周期或 在发射事件的扫描周期内的时间点。 然后计算给定区域的每单位时间的排放事件的变化率，例如通过获得给定区域中的每个子周期中的排放事件的数量，以及通过子周期的值拟合一行。
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公开(公告)号：US20080319304A1
公开(公告)日：2008-12-25
申请号：US12121279
申请日：2008-05-15
申请人： Jerome DECLERCK , Kevin Scott Hakl
发明人： Jerome DECLERCK , Kevin Scott Hakl
IPC分类号： A61B5/055
CPC分类号： G01R33/481 , A61B5/055 , A61B6/037 , A61B6/5247 , G01R33/281
摘要： A method is described for acquiring and analysing the data produced by Positron Emission Tomography (PET), which method provides for an accurate estimation of vascular compartment volume, VB. An MRI scan and the PET scan is performed simultaneously and the results of the former is used to derive a value for VB. The value so derived is then used in pharmacokinetic modelling along with the results of the functional scan.
摘要翻译： 描述了一种用于获取和分析由正电子发射断层扫描（PET）产生的数据的方法，该方法提供了对血管室容积的准确估计。 MRI扫描和PET扫描同时进行，前者的结果用于导出VB的值。 然后将所得的值与功能扫描的结果一起用于药代动力学建模。
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公开(公告)号：US20050238233A1
公开(公告)日：2005-10-27
申请号：US10525005
申请日：2003-08-18
CPC分类号： G06T7/0012 , G06T7/12 , G06T7/149 , G06T2207/10132 , G06T2207/30048
摘要： A method of computing a contour, such as the endocardial boundary in an ultrasound long-axis view of the heart, is disclosed. A plurality of points are input, each point being indicative of a predetermined landmark point in the image. A preliminary contour is then derived based on the input points and a known average contour shape which has been obtained from a database of contours derived from previous images. Finally, the preliminary contour is deformed to fit features identified in the image by a feature-extraction algorithm, to obtain the computed contour.
摘要翻译： 公开了一种在心脏的超声长轴视图中计算轮廓的方法，例如心内膜边界。 输入多个点，每个点指示图像中的预定的地标点。 然后基于输入点和从从先前图像导出的轮廓的数据库获得的已知平均轮廓形状来导出初步轮廓。 最后，通过特征提取算法将预备轮廓变形以适应图像中识别的特征，以获得计算出的轮廓。
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公开(公告)号：US20050065734A1
公开(公告)日：2005-03-24
申请号：US10921473
申请日：2004-08-19
CPC分类号： G06T7/0012
摘要： A technique for assessing the progression of multilateral dysfunction, e.g. bilateral diseases is described. The process consists of two stages: firstly, a ‘health measure’ is computed for each of the features of the multi-lateral dysfunction. One example is in terms of the progression of Parkinson's disease by applying it to the uptake of imaging agent in the two striata of the brain, which can be viewed using SPECT imaging. In this example, a characteristic graph for each striatum is matched to a family of such graphs in order to quantify the state of each striatum as a health measure. Then the lower health measure is plotted against the higher health measure. This point is then projected onto a previously computed disease progression trajectory which is used to assign a percentage to the progression of the disease, from 0% normal to 100% extreme progression of the disease. In addition to the disease progression percentage, the technique also provides a confidence measure of the accuracy of this estimation. The invention is applicable to other forms of multilateral dysfunction, including other human or animal conditions and dysfunction in non-biological systems such as mechanical, electrical or electronic systems.
摘要翻译： 评估多发功能障碍进展的技术，例如 描述双边疾病。 该过程包括两个阶段：首先，为多侧功能障碍的每个特征计算“健康度量”。 就帕金森氏病的进展而言，一个例子是通过将其应用于大脑两条纹状体中的成像剂的摄取，可以使用SPECT成像进行观察。 在该示例中，每个纹状体的特征图与这样的图的族相匹配，以便将每个纹状体的状态量化为健康度量。 然后，较低的健康指标与较高的健康度量相比较。 然后将该点投影到先前计算的疾病进展轨迹上，该轨迹用于将疾病进展的百分比从疾病的0％正常到100％极端进展分配。 除了疾病进展百分比，该技术还提供了该估计精度的置信度量度。 本发明适用于其他形式的多边功能障碍，包括其他人或动物病症和非生物系统如机械，电气或电子系统中的功能障碍。
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公开(公告)号：US20200279369A1
公开(公告)日：2020-09-03
申请号：US16645872
申请日：2018-09-24
发明人： Timor KADIR , Lyndsey PICKUP , Vaclav POTESIL , Jerome DECLERCK
摘要： A Computer Aided Diagnosis, CADx, system (200) is described that comprises: at least one input (210, 212, 214) configured to provide at least one input medical image; and a CADx processing engine (220) configured to receive and process the at least one input medical image and produce at least one CADx score. A CADx score mapping circuit is operably coupled to the CADx processing engine (220) and configured to: map the at least one CADx score to a risk adjusted virtual score; and generate an output (235) of at least the risk adjusted virtual score associated with the processed at least one input medical image. The at least one CADx score and the risk adjusted virtual score correspond to an equivalent risk of condition or disease associated with a patient.
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公开(公告)号：US20100092052A1
公开(公告)日：2010-04-15
申请号：US12575653
申请日：2009-10-08
IPC分类号： G06K9/00
CPC分类号： A61B6/12 , A61B5/20 , A61B5/201 , A61B5/7239 , A61B6/037 , G01T1/00 , G06F19/00 , G06T7/0016 , G06T2207/10104 , G06T2207/30084
摘要： In a method and apparatus for analyzing medical imaging data of a subject from an imaging modality using a tracer, data from detection of tracer emission events at least one region of a scanned imaging volume are obtained, and the data processed to establish sub-periods or time points within a scan period for the emission events. A rate of change of emission events per unit time for a given region is then calculated, for example by obtaining a number of emission events in each sub-period in the given region, and fitting a line through the values for the sub-periods.
摘要翻译： 在使用示踪剂从成像模态分析被检体的医学成像数据的方法和装置中，获得来自扫描成像体积的至少一个区域的示踪剂发射事件的检测的数据，并且处理数据以建立子周期或 在发射事件的扫描周期内的时间点。 然后计算给定区域的每单位时间的排放事件的变化率，例如通过获得给定区域中的每个子周期中的排放事件的数量，以及通过子周期的值拟合一行。
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公开(公告)号：US20210365709A1
公开(公告)日：2021-11-25
申请号：US16755173
申请日：2018-10-15
申请人： Jerome DECLERCK , Timor KADIR , Optellum Limited
发明人： Jerome DECLERCK , Timor KADIR
摘要： A quantification system (700) is described that includes: at least one input (710) configured to provide two input medical images and two locations of interest in said input medical images that correspond to a same anatomical region; and a mapping circuit (725) configured to compute a direct quantification of change of said input medical images from the at least one input (710).
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9.发明授权Method and system for multi-organ segmentation using learning-based segmentation and level set optimization 有权使用基于学习的分割和水平集优化的多器官分割的方法和系统公开(公告)号：US09042620B2
公开(公告)日：2015-05-26
申请号：US13416508
申请日：2012-03-09
申请人： Timo Kohlberger , Michal Sofka , Jens Wetzl , Jingdan Zhang , Shaohua Kevin Zhou , Neil Birkbeck , Jerome Declerck , Jens Kaftan
发明人： Timo Kohlberger , Michal Sofka , Jens Wetzl , Jingdan Zhang , Shaohua Kevin Zhou , Neil Birkbeck , Jerome Declerck , Jens Kaftan
CPC分类号： G06T7/0083 , G06K9/6209 , G06T7/12 , G06T2207/10081 , G06T2207/20081 , G06T2207/20161 , G06T2207/30048 , G06T2207/30084
摘要： A method and system for automatic multi-organ segmentation in a 3D image, such as a 3D computed tomography (CT) volume using learning-base segmentation and level set optimization is disclosed. A plurality of meshes are segmented in a 3D medical image, each mesh corresponding to one of a plurality of organs. A level set in initialized by converting each of the plurality of meshes to a respective signed distance map. The level set optimized by refining the signed distance map corresponding to each one of the plurality of organs to minimize an energy function.
摘要翻译： 公开了一种3D图像自动多器官分割的方法和系统，例如使用学习型基础分割和级别集优化的3D计算机断层摄影（CT）体积。 在3D医学图像中分割多个网格，每个网格对应于多个器官中的一个。 通过将多个网格中的每一个转换为相应的带符号距离图来初始化的级别。 通过精化对应于多个器官中的每一个的有符号距离图来最优化能量函数来优化的级别集合。
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公开(公告)号：US20120170820A1
公开(公告)日：2012-07-05
申请号：US13303445
申请日：2011-11-23
IPC分类号： G06K9/00
CPC分类号： G06T7/30 , G06T2207/10104 , G06T2207/10108
摘要： In a method or apparatus of comparing two image data sets from medical imaging data of a subject, a first, three-dimensional image data set of the subject is obtained. A second, two-dimensional image data set of the subject is also obtained. The first data set is registered with the second data set. Data from the first, three-dimensional image data set is processed to determine a voxel in the first data set which corresponds to a given pixel in the second, two-dimensional image data set.
摘要翻译： 在从对象的医学成像数据中比较两个图像数据集的方法或装置中，获得被摄体的第一，三维图像数据集。 还获得了被摄体的第二个二维图像数据集。 第一数据集被注册到第二数据集。 来自第一，三维图像数据集的数据被处理以确定与第二二维图像数据集中的给定像素相对应的第一数据集中的体素。
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