摘要:
The present invention provides apparatuses and methods for sample analysis, such as tissue analysis, that integrate high wavenumber (HW) Raman spectroscopy for chemical composition analysis and optical coherence tomography (OCT) to provide depth and morphological information. The invention also provides side-viewing optical probes that are based on a single double clad optical fiber for performing the combined HW Raman spectroscopy and OCT. Intravascular catheter embodiments and related vascular diagnostic methods are also provided.
摘要:
The present invention provides apparatuses and methods for sample analysis, such as tissue analysis, that integrate high wavenumber (HW) Raman spectroscopy for chemical composition analysis and spectral-domain optical coherence tomography (SD-OCT) to provide depth and morphological information. Intravascular catheter embodiments and related vascular diagnostic methods are also provided.
摘要:
A chirped pulse amplification (CPA) system and method is described wherein a pulse selector is added after a final amplifier in the system. The pulse selector is configured to select amplified pulses such that the system output repetition rate of the CPA system is below an ASE-limiting repetition rate of the amplifiers. The system may also comprise pulse pickers placed before the final amplifier to control pulse energy of the amplified pulses.
摘要:
Optical and optoelectronic articles incorporating an amorphous diamond-like film are disclosed. Specifically, the invention includes optical or optoelectronic articles containing an amorphous diamond-like film overlying two or more proximate substrates, and to methods of making optical and optoelectronic articles. In certain implementations, the film comprises at least about 30 atomic percent carbon, from about 0 to about 50 atomic percent silicon, and from about 0 to about 50 atomic percent oxygen on a hydrogen-free basis. Another embodiment includes optical or optoelectronic articles containing an amorphous diamond-like film that is further coated with a metallic or polymeric material for attachment to a device package.
摘要:
A method for increasing the photosensitivity of a selected portion of an optical fiber and for producing a grating in the selected portion of an optical fiber. The method includes the step of placing the selected portion of the optical fiber in a hydrogen containing atmosphere. The volume of the hydrogen-containing atmosphere immediately surrounding only the selected portion of the optical fiber is heated to a temperature of at least 250° C. Only the selected portion of the optical fiber is exposed to the heated volume of the hydrogen-containing atmosphere at a temperature of at least 250° C. for a predetermined time.
摘要:
A temperature stabilization package comprises a hollow external housing of a thermally insulating material. The hollow external housing includes a holder and a lid to cover the holder. The holder includes a floor having at least one projection and a separating wall around the projection. An internal surface of the lid has at least one post formed therein. The housing surrounds a container that includes a base and a cover over the base to form an internal cavity inside the container. An outer face of the base has at least one lower socket. The cover includes at least one upper collar so that the container may be coupled inside the hollow external housing by engagement of a lower socket with a projection and an upper collar with a post to hold the container substantially surrounded by, but spaced from, the wall and the hollow external housing. The internal cavity maintains a substantially uniform region of temperature therein, shielded from unstable thermal conditions outside the hollow external housing of the temperature stabilization package.
摘要:
A method and an apparatus for writing arbitrary refractive index perturbations along an optical waveguide. The method includes the steps of providing a waveguide having a photosensitive region and providing a writing beam of actinic radiation having a nominal diameter D, the writing beam defining an optical axis. A waveguide is translated relative to the optical axis of the writing beam at a known velocity v(t). A modulator modulates the radiation intensity I(t) of the writing beam as a function of time t to deliver a fluence of radiation, .PHI.(x), directly to the waveguide, wherein ##EQU1## The refractive index change .DELTA.n.sub.(x) at a position x along the waveguide length is related to the fluence delivered to that position as, .DELTA.n.sub.(x) =C.multidot..PHI..sub.(x), wherein C is a scaling factor that accounts for the photosensitivity of the waveguide.
摘要:
The invention provides optical switching-based systems and methods for catheter-based optical diagnosis which are particularly well suited to determining the condition of blood vessels, including the state of the vessels with respect to atherosclerosis and its development. Various embodiments provide catheter-based spectroscopic systems that are configured to cycle between different optical interrogation techniques such as Raman spectroscopy, optical coherence tomography and time-resolved laser-induced fluorescence spectroscopy. One embodiment of the invention provides an intravascular catheter-based diagnostic system that cycles between fingerprint region (200-2,500 cm−1) Raman spectroscopy and high-wavenumber region (2,500-4,000 cm−1) Raman spectroscopy.
摘要:
The invention provides unitary optics modules that integrate several light management functions for performing optical spectroscopy, such as Raman spectroscopy, and optical spectroscopy systems that include one or more of the unitary optics modules. Methods of using the modules and systems are also provided.
摘要:
Methods for optical isolation in high peak power fiber-optic systems prevent damage to a facet within a fiber-optic isolator caused by back-reflected light from, for example, an optical amplifier. Preventing damage to the facet may include expanding a mode area of the back-reflected light and/or reducing a change in refractive index.