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    AUTOCLAVE OPERATION TO ACCOMMODATE FLUID STERILIZATION CYCLES
    2.
    发明申请
    AUTOCLAVE OPERATION TO ACCOMMODATE FLUID STERILIZATION CYCLES 审中-公开

    公开(公告)号：US20200179548A1

    公开(公告)日：2020-06-11

    申请号：US16705870

    申请日：2019-12-06

    申请人： Immutrix Therapeutics, Inc.

    发明人： Sharif Anani

    IPC分类号： A61L2/24 ,  B01J3/04 ,  A61L2/00 ,  A61L2/07

    摘要： Embodiments relate generally to systems and methods for sterilizing a container comprising a liquid, where a method may comprise placing the container within an autoclave vessel; pressurizing the autoclave vessel to an initial pressure, by pressurizing the autoclave vessel with a clean gas via a first valve; after pressurizing the autoclave vessel to the initial pressure, heating the autoclave vessel to sterilize the liquid within the container within the autoclave vessel; controlling the pressure within the autoclave vessel while heating the autoclave vessel to maintain a pressure within ±10% of the initial pressure via a second valve; and cooling the autoclave vessel after sterilization.

    Universal blood product and methods of preparing and using same
    5.
    发明授权
    Universal blood product and methods of preparing and using same 有权

    公开(公告)号：US11253794B2

    公开(公告)日：2022-02-22

    申请号：US15545233

    申请日：2016-05-27

    申请人： IMMUTRIX THERAPEUTICS, INC.

    发明人： Carol A. Rae ,  Jan S. Simoni ,  John F. Moeller

    IPC分类号： B01D15/20 ,  B01D15/38 ,  B01J20/04 ,  B01J20/28 ,  A61K35/14 ,  B01D15/34 ,  B01J20/20 ,  A61K35/00

    摘要： A method of preparing a universal blood product comprising obtaining a blood product; contacting the blood product with (i) hydroxyapatite; (ii) a carbonaceous material comprising at least a mixture of a first carbon particle having macroporous size α and a second carbon particle having macroporous size β; and (iii) at least one support matrix chemically associated with an antigenic determinant. to form a cleansed product; and recovering the cleansed product. A method of preparing a universal blood product comprising obtaining a blood product; contacting the blood product with (i) hydroxyapatite; (ii) a carbonaceous material comprising at least a mixture of a first carbon particle having macroporous size α and a second carbon particle having macroporous size β; and (iii) at least one support matrix chemically associated with an antigenic determinant. to form a cleansed product; wherein at least one of the hydroxyapatite, carbonaceous material and support matrix is functionalized.