-
公开(公告)号：US20120115202A1
公开(公告)日：2012-05-10
申请号：US13322171
申请日：2010-05-26
Applicant: Nathan Nelson , Iftach Yacoby , Ehud Gazit , Itai Benhar
Inventor： Nathan Nelson , Iftach Yacoby , Ehud Gazit , Itai Benhar
CPC classification number: C12P3/00 , C07K14/80 , C12N9/0077
Abstract: A cyanobacterial cell comprising a PSI complex which accepts electrons from at least one respiratory cytochrome is disclosed. Methods of generating same and use of same for the production of hydrogen gas are also disclosed.
Abstract translation: 公开了一种包含接受来自至少一种呼吸细胞色素的电子的PSI复合物的蓝细菌细胞。 还公开了生产氢气的方法及其使用方法。
-
公开(公告)号：US20110286971A1
公开(公告)日：2011-11-24
申请号：US13159171
申请日：2011-06-13
Applicant: Iftach YACOBY , Eliora Z. Ron , Doron Shabat , Marina Shamis , Itai Benhar
Inventor： Iftach YACOBY , Eliora Z. Ron , Doron Shabat , Marina Shamis , Itai Benhar
IPC: A61K35/76 , C12N7/01 , A61P31/10 , A61P37/06 , A61P31/12 , A61P33/00 , A61P9/10 , A61P35/00 , C12N7/00 , A61P31/04
CPC classification number: A61K47/62
Abstract: The present invention relates to the field of drug delivery. More specifically, the invention relates to the preparation and use of a bacteriophage conjugated through a labile/non labile linker or directly to at least 1,000 therapeutic drug molecules such that the drug molecules are conjugated to the outer surface of the bacteriophage. The bacteriophage optionally displays on its coat a ligand that endows it with specificity towards target cells. Thus, there is provided a targeted, high-capacity drug delivery system useful for the treatment of various pathological conditions.
Abstract translation: 本发明涉及药物递送领域。 更具体地，本发明涉及通过不稳定/非不稳定接头缀合的或直接与至少1,000种治疗性药物分子结合的噬菌体的制备和用途，使得药物分子与噬菌体的外表面缀合。 噬菌体任选地在其外壳上显示赋予其对靶细胞特异性的配体。 因此，提供了可用于治疗各种病理状况的靶向高容量药物递送系统。
-
Patent Agency Ranking
公开(公告)号：US20080057038A1
公开(公告)日：2008-03-06
申请号：US11850942
申请日：2007-09-06
Applicant: Iftach Yacoby , Eliora Ron , Doron Shabat , Marina Shamis , Itai Benhar
Inventor： Iftach Yacoby , Eliora Ron , Doron Shabat , Marina Shamis , Itai Benhar
CPC classification number: A61K47/62
Abstract: The present invention relates to the field of drug delivery. More specifically, the invention relates to the preparation and use of a bacteriophage conjugated through a labile/non labile linker or directly to at least 1,000 therapeutic drug molecules such that the drug molecules are conjugated to the outer surface of the bacteriophage. The bacteriophage optionally displays on its coat a ligand that endows it with specificity towards target cells. Thus, there is provided a targeted, high-capacity drug delivery system useful for the treatment of various pathological conditions.
Abstract translation: 本发明涉及药物递送领域。 更具体地，本发明涉及通过不稳定/非不稳定接头缀合的或直接与至少1,000种治疗性药物分子结合的噬菌体的制备和用途，使得药物分子与噬菌体的外表面缀合。 噬菌体任选地在其外壳上显示赋予其对靶细胞特异性的配体。 因此，提供了可用于治疗各种病理状况的靶向高容量药物递送系统。
-
公开(公告)号：US08563294B2
公开(公告)日：2013-10-22
申请号：US13322171
申请日：2010-05-26
Applicant: Nathan Nelson , Iftach Yacoby , Ehud Gazit , Itai Benhar
Inventor： Nathan Nelson , Iftach Yacoby , Ehud Gazit , Itai Benhar
CPC classification number: C12P3/00 , C07K14/80 , C12N9/0077
Abstract: A cyanobacterial cell comprising a PSI complex which accepts electrons from at least one respiratory cytochrome is disclosed. Methods of generating same and use of same for the production of hydrogen gas are also disclosed.
Abstract translation: 公开了一种包含接受来自至少一种呼吸细胞色素的电子的PSI复合物的蓝细菌细胞。 还公开了生产氢气的方法及其使用方法。
-
公开(公告)号：US20100203609A1
公开(公告)日：2010-08-12
申请号：US12670407
申请日：2008-07-23
Applicant: Iftach Yacoby , Ehud Gazit , Nathan Nelson , Itai Benhar
Inventor： Iftach Yacoby , Ehud Gazit , Nathan Nelson , Itai Benhar
CPC classification number: C12P3/00 , C12M21/02 , C12M21/18 , C12M31/10 , C12M47/10 , C12N9/0067 , C12N9/96 , C12N15/62 , C12Y112/98002
Abstract: An isolated polypeptide comprising a hydrogen generating enzyme attached to a heterologous ferredoxin is disclosed, as well as polynucleotides encoding same, nucleic acid constructs capable of expressing same and cells expressing same. A method for generating hydrogen using the isolated polypeptide is also disclosed.
Abstract translation: 公开了包含与异源铁氧还蛋白连接的产氢酶的分离的多肽，以及编码其的多核苷酸，能够表达其的核酸构建体和表达相同的细胞。 还公开了使用分离的多肽产生氢的方法。
-
公开(公告)号：US09181555B2
公开(公告)日：2015-11-10
申请号：US12670407
申请日：2008-07-23
Applicant: Iftach Yacoby , Ehud Gazit , Nathan Nelson , Itai Benhar
Inventor： Iftach Yacoby , Ehud Gazit , Nathan Nelson , Itai Benhar
CPC classification number: C12P3/00 , C12M21/02 , C12M21/18 , C12M31/10 , C12M47/10 , C12N9/0067 , C12N9/96 , C12N15/62 , C12Y112/98002
Abstract: An isolated polypeptide comprising a hydrogen generating enzyme attached to a heterologous ferredoxin is disclosed, as well as polynucleotides encoding same, nucleic acid constructs capable of expressing same and cells expressing same. A method for generating hydrogen using the isolated polypeptide is also disclosed.
Abstract translation: 公开了包含与异源铁氧还蛋白连接的产氢酶的分离的多肽，以及编码其的多核苷酸，能够表达其的核酸构建体和表达相同的细胞。 还公开了使用分离的多肽产生氢的方法。
-
公开(公告)号：US07985573B2
公开(公告)日：2011-07-26
申请号：US11850942
申请日：2007-09-06
Applicant: Iftach Yacoby , Eliora Z. Ron , Doron Shabat , Marina Shamis , Itai Benhar
Inventor： Iftach Yacoby , Eliora Z. Ron , Doron Shabat , Marina Shamis , Itai Benhar
CPC classification number: A61K47/62
Abstract: The present invention relates to the field of drug delivery. More specifically, the invention relates to the preparation and use of a bacteriophage conjugated through a labile/non labile linker or directly to at least 1,000 therapeutic drug molecules such that the drug molecules are conjugated to the outer surface of the bacteriophage. The bacteriophage optionally displays on its coat a ligand that endows it with specificity towards target cells. Thus, there is provided a targeted, high-capacity drug delivery system useful for the treatment of various pathological conditions.
Abstract translation: 本发明涉及药物递送领域。 更具体地，本发明涉及通过不稳定/非不稳定接头缀合的或直接与至少1,000种治疗性药物分子结合的噬菌体的制备和用途，使得药物分子与噬菌体的外表面缀合。 噬菌体任选地在其外壳上显示赋予其对靶细胞特异性的配体。 因此，提供了可用于治疗各种病理状况的靶向高容量药物递送系统。
-
-
-
-
-
-
Search Results
7
records
(took 0.02 seconds)
