公开(公告)号：US20220054418A1

公开(公告)日：2022-02-24

申请号：US17461713

申请日：2021-08-30

申请人： ICEUTICA PTY LTD.

发明人： Raffaele Cammarano ,  Felix Meiser ,  Almar Postma ,  Frank Caruso

IPC分类号： A61K9/14 ,  A61K9/51 ,  A61K31/192 ,  A61K31/196 ,  A61K31/435 ,  A61K31/4985 ,  A61K31/5513 ,  A61K31/4535 ,  A61K31/551

摘要： A method for producing a composition comprising nanoparticles of a biologically active compound.

公开(公告)号：US20210213028A1

公开(公告)日：2021-07-15

申请号：US17300136

申请日：2021-03-18

申请人： ICEUTICA PTY LTD.

发明人： H. William Bosch

IPC分类号： A61K31/5415 ,  A61K9/14 ,  A61K9/16 ,  A61K9/48 ,  A61K9/00 ,  A61K31/00

摘要： Unit dosage forms of meloxicam containing either 5 mg or 10 mg of meloxicam that provide effective pain relief and have desirable pharmacokinetic properties are described. The unit dosage forms can provide pain relief when a single unit dose is administered to a patient and useful for treating pain such as osteoarthritis pain at a relatively low systemic exposure to meloxicam.

公开(公告)号：US20200085835A1

公开(公告)日：2020-03-19

申请号：US16689032

申请日：2019-11-19

申请人： ICEUTICA PTY LTD.

发明人： H. William Bosch

IPC分类号： A61K31/5415 ,  A61K31/00 ,  A61K9/14 ,  A61K9/16 ,  A61K9/00 ,  A61K9/48

摘要： Unit dosage forms of meloxicam containing either 5 mg or 10 mg of meloxicam that provide effective pain relief and have desirable pharmacokinetic properties are described. The unit dosage forms can provide pain relief when a single unit dose is administered to a patient and useful for treating pain such as osteoarthritis pain at a relatively low systemic exposure to meloxicam.

公开(公告)号：US20190193085A1

公开(公告)日：2019-06-27

申请号：US16289491

申请日：2019-02-28

申请人： ICEUTICA PTY LTD.

发明人： Aaron Dodd ,  Felix Meiser ,  Marck Norret ,  Adrian Russell ,  H. William Bosch

IPC分类号： B02C17/10 ,  A61K31/196 ,  A61K9/14 ,  A01N47/10 ,  A01N57/20 ,  A61K31/137 ,  A61K31/192 ,  A61K31/405 ,  A61K31/415 ,  A61K31/421 ,  A61K31/496 ,  A61K31/5415 ,  A01N25/34 ,  A23P10/30 ,  A61K9/16 ,  A01N39/04

CPC分类号： B02C17/10 ,  A01N25/34 ,  A01N39/04 ,  A01N47/10 ,  A01N57/20 ,  A23P10/30 ,  A61K9/14 ,  A61K9/145 ,  A61K9/146 ,  A61K9/1617 ,  A61K9/1623 ,  A61K9/1635 ,  A61K9/1652 ,  A61K31/137 ,  A61K31/192 ,  A61K31/196 ,  A61K31/405 ,  A61K31/415 ,  A61K31/421 ,  A61K31/496 ,  A61K31/5415

摘要： The present invention relates to methods for producing particles of a biologically active material using dry milling processes as well as compositions comprising such materials, medicaments produced using said biologically active materials in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of said biologically active materials administered by way of said medicaments.

公开(公告)号：US20180194759A1

公开(公告)日：2018-07-12

申请号：US15914377

申请日：2018-03-07

申请人： iCeutica Pty Ltd.

发明人： Aaron DODD ,  Felix MEISER ,  Marck NORRET ,  Adrian RUSSELL ,  H. William BOSCH

IPC分类号： C07D417/12

CPC分类号： C07D417/12 ,  A61K9/14 ,  A61K9/143 ,  A61K9/145 ,  A61K9/146 ,  A61K9/5115 ,  A61K9/5123 ,  A61K9/513 ,  A61K31/5415 ,  B02C23/06 ,  B63B22/026 ,  B63B27/34 ,  B63B2035/442 ,  B63B2035/448 ,  B65H75/38 ,  B65H75/4402 ,  B65H75/4415 ,  B65H75/4486 ,  B65H2701/33 ,  B67D9/00 ,  Y02A50/465 ,  Y10T428/2982

摘要： The present invention relates to methods for producing particles of meloxicam using dry milling processes as well as compositions comprising meloxicam, medicaments produced using meloxicam in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of meloxicam administered by way of said medicaments.

公开(公告)号：US09808468B2

公开(公告)日：2017-11-07

申请号：US15595446

申请日：2017-05-15

申请人： ICEUTICA PTY LTD.

发明人： H. William Bosch

IPC分类号： A61K31/5415 ,  A61K31/00 ,  A61K9/16 ,  A61K9/14

CPC分类号： A61K31/5415 ,  A61K9/0053 ,  A61K9/14 ,  A61K9/145 ,  A61K9/1617 ,  A61K9/1623 ,  A61K9/1652 ,  A61K9/4858 ,  A61K31/00 ,  Y10T428/2982

摘要： Unit dosage forms of meloxicam containing either 5 mg or 10 mg of meloxicam that provide effective pain relief and have desirable pharmacokinetic properties are described. The unit dosage forms can provide pain relief when a single unit dose is administered to a patient and useful for treating pain such as osteoarthritis pain at a relatively low systemic exposure to meloxicam.

公开(公告)号：US09649318B2

公开(公告)日：2017-05-16

申请号：US14974108

申请日：2015-12-18

申请人： ICEUTICA PTY LTD.

发明人： H. William Bosch

IPC分类号： A61K31/5415 ,  A61K31/00 ,  A61K9/16 ,  A61K9/14

CPC分类号： A61K31/5415 ,  A61K9/0053 ,  A61K9/14 ,  A61K9/145 ,  A61K9/1617 ,  A61K9/1623 ,  A61K9/1652 ,  A61K9/4858 ,  A61K31/00 ,  Y10T428/2982

摘要： Unit dosage forms of meloxicam containing either 5 mg or 10 mg of meloxicam that provide effective pain relief and have desirable pharmacokinetic properties are described. The unit dosage forms can provide pain relief when a single unit dose is administered to a patient and useful for treating pain such as osteoarthritis pain at a relatively low systemic exposure to meloxicam.

公开(公告)号：US09522135B2

公开(公告)日：2016-12-20

申请号：US14810240

申请日：2015-07-27

申请人： ICEUTICA PTY LTD.

发明人： Aaron Dodd ,  Felix Meiser ,  Marck Norret ,  Adrian Russell ,  H. William Bosch

IPC分类号： A61K31/405 ,  B82Y5/00 ,  A61J3/02 ,  A61K9/14 ,  A61K9/51

CPC分类号： A61K31/405 ,  A61J3/02 ,  A61K9/14 ,  A61K9/143 ,  A61K9/145 ,  A61K9/146 ,  A61K9/5115 ,  A61K9/5123 ,  A61K9/513 ,  A61K9/5192 ,  B82Y5/00 ,  Y10S977/915 ,  Y10T428/2982

摘要： The present invention relates to methods for producing particles of indomethacin using dry milling processes as well as compositions comprising indomethacin, medicaments produced using indomethacin in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of indomethacin administered by way of said medicaments.

公开(公告)号：US20160102086A1

公开(公告)日：2016-04-14

申请号：US14970048

申请日：2015-12-15

申请人： iCeutica Pty Ltd.

发明人： Aaron DODD ,  Felix MEISER ,  Marck NORRET ,  Adrian RUSSELL ,  H. William BOSCH

IPC分类号： C07D417/12 ,  B02C23/06

CPC分类号： C07D417/12 ,  A61K9/14 ,  A61K9/143 ,  A61K9/145 ,  A61K9/146 ,  A61K9/5115 ,  A61K9/5123 ,  A61K9/513 ,  A61K31/5415 ,  B02C23/06 ,  B63B22/026 ,  B63B27/34 ,  B63B2035/442 ,  B63B2035/448 ,  B65H75/38 ,  B65H75/4402 ,  B65H75/4415 ,  B65H75/4486 ,  B65H2701/33 ,  B67D9/00 ,  Y02A50/465 ,  Y10T428/2982

摘要： The present invention relates to methods for producing particles of meloxicam using dry milling processes as well as compositions comprising meloxicam, medicaments produced using meloxicam in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of meloxicam administered by way of said medicaments.

摘要翻译： 本发明涉及使用干磨法生产美洛昔康颗粒的方法以及包含美洛昔康的组合物，使用颗粒形式和/或组合物的美洛昔康制备的药物以及使用治疗有效的方法治疗动物（包括人）的方法 通过所述药物施用的美洛昔康的量。

公开(公告)号：US09089471B2

公开(公告)日：2015-07-28

申请号：US14284981

申请日：2014-05-22

申请人： ICEUTICA PTY LTD.

发明人： Aaron Dodd ,  Felix Meiser ,  Marck Norret ,  Adrian Russell ,  H. William Bosch

IPC分类号： A61J3/02 ,  A61K31/405 ,  A61K9/14 ,  A61K9/51 ,  B82Y5/00

CPC分类号： A61K31/405 ,  A61J3/02 ,  A61K9/14 ,  A61K9/143 ,  A61K9/145 ,  A61K9/146 ,  A61K9/5115 ,  A61K9/5123 ,  A61K9/513 ,  A61K9/5192 ,  B82Y5/00 ,  Y10S977/915 ,  Y10T428/2982

摘要： The present invention relates to methods for producing particles of indomethacin using dry milling processes as well as compositions comprising indomethacin, medicaments produced using indomethacin in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of indomethacin administered by way of said medicaments.

摘要翻译： 本发明涉及使用干磨法生产吲哚美辛颗粒的方法以及包含消炎痛的组合物，使用颗粒形式的消炎痛产生的药物和/或组合物，以及使用治疗有效的方法治疗动物（包括人）的方法 通过所述药物施用的吲哚美辛量。