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公开(公告)号：US20140037647A1
公开(公告)日：2014-02-06
申请号：US14112358
申请日：2012-03-28
Applicant: Mark A. Rubin , Himisha Beltran
Inventor： Mark A. Rubin , Himisha Beltran
CPC classification number: G01N33/6893 , A61K31/00 , A61K31/437 , A61K31/444 , A61K31/496 , A61K31/506 , A61K31/519 , A61K31/5377 , A61K31/55 , A61K31/675 , A61K31/713 , C12Q1/6886 , C12Q2600/112 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , G01N2333/82 , G01N2333/91215
Abstract: Disclosed herein are new prognostic molecular markers for prostate cancer. More specifically, the invention has identified that overexpression or amplification of at least one of AURKA or MYCN define a distinct subgroup of prostate cancer that is predisposed to the development of lethal NEPC, who will benefit from early intervention.
Abstract translation: 本文公开了用于前列腺癌的新的预后分子标记。 更具体地，本发明已经确定，AURKA或MYCN中的至少一种的过度表达或扩增定义了易于发生致死性NEPC的前列腺癌的不同亚组，其将受益于早期干预。
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公开(公告)号：US09568483B2
公开(公告)日：2017-02-14
申请号：US14112358
申请日：2012-03-28
Applicant: Mark A. Rubin , Himisha Beltran
Inventor： Mark A. Rubin , Himisha Beltran
IPC: C12Q1/68 , C07H21/04 , G01N33/68 , G01N33/574 , A61K31/00 , A61K31/437 , A61K31/444 , A61K31/496 , A61K31/506 , A61K31/519 , A61K31/5377 , A61K31/55 , A61K31/675 , A61K31/713
CPC classification number: G01N33/6893 , A61K31/00 , A61K31/437 , A61K31/444 , A61K31/496 , A61K31/506 , A61K31/519 , A61K31/5377 , A61K31/55 , A61K31/675 , A61K31/713 , C12Q1/6886 , C12Q2600/112 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , G01N2333/82 , G01N2333/91215
Abstract: Disclosed herein are new prognostic molecular markers for prostate cancer. More specifically, the invention has identified that overexpression or amplification of at least one of AURKA or MYCN define a distinct subgroup of prostate cancer that is predisposed to the development of lethal NEPC, who will benefit from early intervention.
Abstract translation: 本文公开了用于前列腺癌的新的预后分子标记。 更具体地，本发明已经确定，AURKA或MYCN中的至少一种的过度表达或扩增定义了易于发生致死性NEPC的前列腺癌的不同亚组，其将受益于早期干预。
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