公开(公告)号：US20070213579A1

公开(公告)日：2007-09-13

申请号：US11748418

申请日：2007-05-14

Applicant: Anant Hegde ,  Halil Karabey

Inventor： Anant Hegde ,  Halil Karabey

IPC: A61N1/362

CPC classification number: A61M1/122 ,  A61B5/0215 ,  A61B5/042 ,  A61B5/0452 ,  A61B5/4836 ,  A61B5/6876 ,  A61B2017/00871 ,  A61M1/1053 ,  A61M1/1058 ,  A61M1/106 ,  A61M1/1067 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/127 ,  A61M2205/0283 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/8243 ,  H01L41/27

Abstract: Several electroactive polymer (EAP) actuated vascular assist devices are provided that can be readily implanted within the body of a patient without coming in direct blood contact. The devices are also readily repositioned and/or removed from contact with the internal vasculature or may even be turned OFF remotely. In addition, there is provided a method of fabrication and a method of implanting such devices. There are also provided methods for the augmentation of a body lumen through the use of hemodynamic signals such as pressure or ECG signals to synchronize EAP actuation in the vascular assist system.

Abstract translation: 提供了几种电活性聚合物（EAP）致动的血管辅助装置，其可以容易地植入患者的身体内而不会直接接触血液。 这些装置也容易地重新定位和/或从与内部脉管系统的接触中去除或者甚至可以远程关闭。 此外，提供了一种制造方法和一种植入这种装置的方法。 还提供了通过使用诸如压力或ECG信号之类的血液动力学信号来增加体腔的方法来同步血管辅助系统中的EAP致动。

公开(公告)号：US20060229669A1

公开(公告)日：2006-10-12

申请号：US11340183

申请日：2006-01-25

Applicant: Michael Mirizzi ,  Anna Prestezog ,  Halil Karabey ,  John Rodriguez

Inventor： Michael Mirizzi ,  Anna Prestezog ,  Halil Karabey ,  John Rodriguez

IPC: A61B17/08

CPC classification number: A61B17/12186 ,  A61B17/06 ,  A61B17/12022 ,  A61B17/12031 ,  A61B17/12036 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B17/12181 ,  A61B17/1219 ,  A61B17/122 ,  A61B2017/00898 ,  A61B2017/0474 ,  A61B2017/06176 ,  A61B2017/1205

Abstract: A method of treating a vein comprises accessing a vein at an access point spaced from a sapheno-femoral junction. A bioabsorbable fibrous body is implanted into the vein through the access point. The body is moved in the vein toward the sapheno-femoral junction.

Abstract translation: 治疗静脉的方法包括在与隐窝 - 股骨连接处间隔开的入口处进入静脉。 通过接入点将生物可吸收纤维体植入静脉。 身体静脉移动到隐窝股骨交界处。

公开(公告)号：US20060229668A1

公开(公告)日：2006-10-12

申请号：US11339975

申请日：2006-01-25

Applicant: Anna Prestezog ,  Michael Mirizzi ,  Halil Karabey ,  John Rodriguez ,  Russell Thompson

Inventor： Anna Prestezog ,  Michael Mirizzi ,  Halil Karabey ,  John Rodriguez ,  Russell Thompson

IPC: A61B17/08

CPC classification number: A61B17/12186 ,  A61B17/06 ,  A61B17/12022 ,  A61B17/12031 ,  A61B17/12036 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B17/12181 ,  A61B17/1219 ,  A61B17/122 ,  A61B2017/00898 ,  A61B2017/0474 ,  A61B2017/06176 ,  A61B2017/1205

Abstract: A method of treating a hollow anatomical structure of a patient comprises implanting a bioabsorbable fibrous body in a hollow anatomical structure. The body is secured in the hollow anatomical structure to limit migration of the body within the hollow anatomical structure.

公开(公告)号：US20060212055A1

公开(公告)日：2006-09-21

申请号：US11339927

申请日：2006-01-25

Applicant: Halil Karabey ,  Anna Prestezog ,  Michael Mirizzi

Inventor： Halil Karabey ,  Anna Prestezog ,  Michael Mirizzi

IPC: A61F2/01

CPC classification number: A61B17/12186 ,  A61B17/06 ,  A61B17/12022 ,  A61B17/12031 ,  A61B17/12036 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B17/12181 ,  A61B17/1219 ,  A61B17/122 ,  A61B2017/00898 ,  A61B2017/0474 ,  A61B2017/06176 ,  A61B2017/1205

Abstract: An apparatus for treating a hollow anatomical structure comprises an implant comprising a plurality of bioabsorbable fibers. The implant has a compressed state in which the implant can fit within a cylindrical tube having an inside diameter of 8 French or less. The implant is expandable from the compressed state to an expanded state in which the implant has sufficient size to span the inside diameter of a cylindrical tube having an inside diameter of 12 French or greater.

公开(公告)号：US20050137712A1

公开(公告)日：2005-06-23

申请号：US10971505

申请日：2004-10-22

Applicant: Michael Biggs ,  Thomas Keast ,  Bryan Loomas ,  Don Tanaka ,  David Thompson ,  Gary Kaplan ,  Kelly Shriner ,  Halil Karabey ,  Russ Redmond ,  Claude Vidal ,  Mike Collinson ,  Cary Cole ,  Michael Willink

Inventor： Michael Biggs ,  Thomas Keast ,  Bryan Loomas ,  Don Tanaka ,  David Thompson ,  Gary Kaplan ,  Kelly Shriner ,  Halil Karabey ,  Russ Redmond ,  Claude Vidal ,  Mike Collinson ,  Cary Cole ,  Michael Willink

IPC: A61F2/02 ,  A61B17/00 ,  A61B17/02 ,  A61B17/064 ,  A61B17/068 ,  A61B17/12 ,  A61F2/04 ,  A61F2/86

CPC classification number: A61F2/86 ,  A61B17/0218 ,  A61B17/064 ,  A61B17/068 ,  A61B17/12022 ,  A61B17/12104 ,  A61B17/12172 ,  A61B2017/00252 ,  A61B2017/0046 ,  A61B2017/00477 ,  A61F2/07 ,  A61F2/2412 ,  A61F2/91 ,  A61F2002/043 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0078

Abstract: Devices and methods are directed to improving the gaseous exchange in a lung of an individual having, for instance, chronic obstructive pulmonary disease. More particularly, conduits may be deployed in the lung to maintain collateral openings (or channels) surgically created through airway walls. This tends to facilitate both the exchange of oxygen ultimately into the blood and decompress hyper-inflated lungs.

公开(公告)号：US20110251592A1

公开(公告)日：2011-10-13

申请号：US12939961

申请日：2010-11-04

Applicant: Michael BIGGS ,  Thomas KEAST ,  Bryan LOOMAS ,  Don TANAKA ,  David THOMPSON ,  Gary KAPLAN ,  Kelly SHRINER ,  Halil KARABEY ,  Russ REDMOND ,  Claude VIDAL ,  Mike COLLINSON ,  Cary COLE ,  Michael WILLINK

Inventor： Michael BIGGS ,  Thomas KEAST ,  Bryan LOOMAS ,  Don TANAKA ,  David THOMPSON ,  Gary KAPLAN ,  Kelly SHRINER ,  Halil KARABEY ,  Russ REDMOND ,  Claude VIDAL ,  Mike COLLINSON ,  Cary COLE ,  Michael WILLINK

IPC: A61M25/00 ,  A61B18/18

CPC classification number: A61F2/86 ,  A61B17/0218 ,  A61B17/064 ,  A61B17/068 ,  A61B17/12022 ,  A61B17/12104 ,  A61B17/12172 ,  A61B2017/00252 ,  A61B2017/0046 ,  A61B2017/00477 ,  A61F2/07 ,  A61F2/2412 ,  A61F2/91 ,  A61F2002/043 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0078

Abstract: Devices and methods are directed to improving the gaseous exchange in a lung of an individual having, for instance, chronic obstructive pulmonary disease. More particularly, conduits may be deployed in the lung to maintain collateral openings (or channels) surgically created through airway walls. This tends to facilitate both the exchange of oxygen ultimately into the blood and decompress hyper-inflated lungs. The conduit includes a radially expandable center section having a first end, a second end, and a passageway extending from the first end to the second end. A control segment may be associated with the conduit to limit the degree of radial expansion. The conduit further includes a plurality of deflectable members extending from the ends of the center section. A tissue barrier may coaxially surround the conduit such that tissue ingrowth is prevented. The conduits may also include hold-down members and bioactive coatings that serve to prevent ejection of the conduit as well as prevent narrowing of the passageway due to tissue ingrowth.

Abstract translation: 装置和方法旨在改善具有例如慢性阻塞性肺疾病的个体的肺中的气体交换。 更具体地，导管可以部署在肺中以保持通过气道壁手术产生的侧支开口（或通道）。 这倾向于促进氧气最终进入血液并减压超膨胀的肺。 导管包括具有第一端，第二端和从第一端延伸到第二端的通道的可径向扩张的中心部分。 控制段可以与管道相关联以限制径向膨胀的程度。 导管还包括从中心部分的端部延伸的多个可偏转构件。 组织屏障可以同轴地围绕导管，从而防止组织向内生长。 导管还可以包括用于防止导管喷射的压紧构件和生物活性涂层，并且防止由于组织向内生长导致的通道变窄。

公开(公告)号：US20060293647A1

公开(公告)日：2006-12-28

申请号：US11472793

申请日：2006-06-22

Applicant: Robert McRae ,  Michael Mirizzi ,  Brady Esch ,  Anna Prestezog ,  Todd Schoenberger ,  Halil Karabey ,  Jeff Zalewski

Inventor： Robert McRae ,  Michael Mirizzi ,  Brady Esch ,  Anna Prestezog ,  Todd Schoenberger ,  Halil Karabey ,  Jeff Zalewski

IPC: A61B18/04 ,  A61M31/00

CPC classification number: A61B18/18 ,  A61B18/1477 ,  A61B18/1492 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00404 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2218/002 ,  A61M25/0068 ,  A61M25/0074 ,  A61M25/0082 ,  A61M25/0084 ,  A61M2025/0087 ,  A61M2202/0007 ,  A61M2210/12

Abstract: A catheter is usable to treat a hollow anatomical structure (HAS). The catheter comprises one or more shafts which extend away from a proximal end of the catheter toward a distal end thereof. The catheter further comprises an HAS constriction energy source located at or near the distal end of the catheter. The catheter further comprises at least one radially expandable transmural fluid delivery channel located in the catheter near the HAS constriction energy source.

公开(公告)号：US20060212127A1

公开(公告)日：2006-09-21

申请号：US11339978

申请日：2006-01-25

Applicant: Halil Karabey ,  Anna Prestezog ,  Michael Mirizzi ,  Brian Farley ,  John Rodriguez ,  Russell Thompson

Inventor： Halil Karabey ,  Anna Prestezog ,  Michael Mirizzi ,  Brian Farley ,  John Rodriguez ,  Russell Thompson

IPC: A61F2/04 ,  A61F2/06

CPC classification number: A61B17/12186 ,  A61B17/06 ,  A61B17/12022 ,  A61B17/12031 ,  A61B17/12036 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B17/12181 ,  A61B17/1219 ,  A61B17/122 ,  A61B2017/00898 ,  A61B2017/0474 ,  A61B2017/06176 ,  A61B2017/1205

Abstract: An apparatus for treating a hollow anatomical structure comprises an implant sized for insertion into a hollow anatomical structure. The implant comprises a plurality of loose, bulked fibers. The fibers are formed from one or more bioabsorbable materials.

Abstract translation: 用于治疗中空解剖结构的装置包括尺寸适于插入中空解剖结构中的植入物。 植入物包括多个松散的膨松纤维。 纤维由一种或多种生物可吸收材料形成。

公开(公告)号：US20070248640A1

公开(公告)日：2007-10-25

申请号：US11407858

申请日：2006-04-20

Applicant: Halil Karabey ,  Michael Mirizzi ,  Anna Prestezog

Inventor： Halil Karabey ,  Michael Mirizzi ,  Anna Prestezog

IPC: A61F2/00

CPC classification number: A61B17/12022 ,  A61B17/0057 ,  A61B17/0401 ,  A61B17/12036 ,  A61B17/12109 ,  A61B17/12159 ,  A61B17/12172 ,  A61B17/12181 ,  A61B17/1219 ,  A61B2017/00637 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/0443 ,  A61B2017/06176 ,  A61B2017/1205

Abstract: Apparatus and methods for treating a hollow anatomical structure comprises an implant sized for insertion into a hollow anatomical structure. The implant comprises a plurality of loose, bulked fibers. The fibers are formed from one or more bioabsorbable materials. Upon implantation, the apparatus causes a partial occlusion of the hollow anatomical structure, followed by a complete or substantially complete occlusion.

Abstract translation: 用于治疗中空解剖结构的装置和方法包括尺寸适于插入中空解剖结构中的植入物。 植入物包括多个松散的膨松纤维。 纤维由一种或多种生物可吸收材料形成。 植入后，该装置引起中空解剖结构的部分闭塞，随后完全或完全闭塞。

公开(公告)号：US20060052822A1

公开(公告)日：2006-03-09

申请号：US11212539

申请日：2005-08-26

Applicant: Michael Mirizzi ,  Halil Karabey ,  Anna Prestezog ,  Bob McRae

Inventor： Michael Mirizzi ,  Halil Karabey ,  Anna Prestezog ,  Bob McRae

IPC: A61B17/08

CPC classification number: A61B17/12022 ,  A61B17/00491 ,  A61B17/12109 ,  A61B17/12181 ,  A61B17/12186 ,  A61B17/1219 ,  A61B17/12195 ,  A61B2017/00004 ,  A61L24/0042 ,  A61L31/148

Abstract: This invention relates to occlusion of a hollow anatomical structure by inserting an occluding device or occluding material into a hollow anatomical structure or surrounding native tissue.

Abstract translation: 本发明涉及通过将闭塞装置或闭塞材料插入中空解剖结构或周围的天然组织来封闭中空解剖结构。