Device for detecting molecules, method for detecting molecules
    2.
    发明申请
    Device for detecting molecules, method for detecting molecules 审中-公开
    检测分子的装置,检测分子的方法

    公开(公告)号:US20060127949A1

    公开(公告)日:2006-06-15

    申请号:US11233913

    申请日:2005-09-23

    CPC classification number: G01N33/6845 C07K16/00 C07K2317/567 C07K2317/569

    Abstract: A construct is provided that is capable of binding a plurality of molecules, the construct comprising a first moiety with a first molecule binding region and a first molecule non-binding region; and a second moiety with a second molecule-binding region and a second molecule-non-binding region, whereby the first binding region and second binding region are at opposite ends of the construct. Also provided is a method for detecting protein having certain amino acid sequences, the method comprising supplying a collection of proteins each with unknown amino acid sequences, contacting the collection with a moiety having a plurality of binding sites capable of binding with the protein having certain amino acid sequences so as to form a moiety-protein complex, and mixing the complex with a marker specific for the moiety in an amount sufficient to indicate existence of the complex

    Abstract translation: 提供能够结合多个分子的构建体,所述构建体包含具有第一分子结合区域和第一分子非结合区域的第一部分; 和具有第二分子结合区和第二分子 - 非结合区的第二部分,其中第一结合区和第二结合区位于构建体的相对端。 还提供了一种用于检测具有某些氨基酸序列的蛋白质的方法,所述方法包括提供各自具有未知氨基酸序列的蛋白质的集合,使所述收集物与具有多个能够与具有某些氨基酸的蛋白质结合的结合位点的部分接触 酸序列,以便形成部分 - 蛋白质复合物,并将复合物与足以表明复合物存在的量的该部分特异性标记物混合

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