Abstract:
The present invention provides a novel CXCL12-α2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
Abstract:
A system for aligning the bit of a hand-held tool with the surface of a workpiece wherein a laser beam essentially parallel to the axis of the bit is projected forwardly toward the workpiece and onto a mirror maintained at a preselected angle to the workpiece surface. The incident beam is reflected backwardly onto means detecting both the incident beam and the reflected beam and indicating when the beams are coincident.
Abstract:
An force generator includes an elongate force generator body that has a longitudinal dimension and has a fluid chamber defined therein. The force generator body exhibits a dimensional extension responsive to an increase in fluid in the fluid chamber and a dimensional retraction responsive to a decrease in fluid in the fluid chamber. A restraint apparatus channels the dimensional extension/retraction into the longitudinal dimension and restrains dimensional extension in a dimension transverse thereto.
Abstract:
A cable comprising helically wound superelastic fibers and having a drilling tip provided at its distal end is housed in an elongated holder through which the cable may be advanced, the holder having a distal end for supporting the cable during a drilling operation and through which the distal end of the cable may protrude. The holder includes contains a cable support shaped to bend the cable through a predetermined angle adjacent its distal end and to support the cable as it is rotated and advanced. A motor is attached to the cable remote from the distal end of the cable to rotate the cable in a direction tending to tighten the cable fibers.
Abstract:
A tamper-resistant vehicle event recorder having a combustible film on a polymeric substrate, an ignition mechanism for igniting the combustible coating and an activation mechanism connected to the ignition mechanism for activating the ignition mechanism in response to a vehicular event.
Abstract:
A multi-position tailgate having a movable gate panel. The gate panel is pivotally mounted in a gate frame. The gate frame is hinged to the rear edge of the cargo bed. The gate panel is hinged to the top of the gate frame. Rotation of panel about the two axis permits the gate panel to be positioned parallel to the cargo bed.
Abstract:
An aspiration device for laparoscopic surgery has a tube with a proximal end. A tool access port concentric with the tube permits insertion of a grasping tool for holding a sponge at the distal end of the tube.
Abstract:
A surgical instrument having a surgeon operable control handle for grasping surgical needles or other objects. The instrument has a moveable jaw opposed to a fixed jaw. The control handle engages a clamping spring which closes the jaws and exerts a grasping force which is proportional to the size of the object located between the jaws.
Abstract:
A die (20) particularly adapted for making a screw blank having a reduced diameter, offset or asymmetric section has a first die section (30) having a central bore (32), which mates with a second die section (50) having a smaller diameter and/or offset bore (52). A shaped end (57) of the smaller or offset bore (52), which forms the reduced diameter, offset or asymmetric section of a screw blank, is coated with a hard lubricating material. The method of manufacturing the die (20) involves making two first die sections (30), which are preferably identical, from a first die body (130), and two second die sections (50), which are also preferably identical and adapted to mate with the first die section (30), from a second die body (150).
Abstract:
An improved mounting part is designed for use in securing plastic panels to a metal framework. The mounting part comprises a base plate which is mechanically fastened to the framework by means of substantially oblong cups which are inserted into corresponding slots in the framework and then deformed into round; and a rectangular block for receiving a screw. The plastic panel is secured to the framework by means of a screw threaded fastener which is inserted through an opening in the panel and screwed into a guide hole drilled into the rectangular block and then into the framework. The improved fastener eliminates problems of rust initiation caused by the welded mounting part of the prior art, and acts as a combination of a stand-off washer and a nut.