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    Roadmap for controlling malaria
    1.
    发明授权
    Roadmap for controlling malaria 有权

    公开(公告)号：US11000580B2

    公开(公告)日：2021-05-11

    申请号：US13997269

    申请日：2011-12-20

    申请人： Eng Hong Lee

    发明人： Eng Hong Lee

    IPC分类号： A61K39/00 ,  A61K39/002 ,  A61K39/015 ,  A61K49/00 ,  A61K39/012

    摘要： Embodiments of the present invention concern methods of preventing malaria in a target population of humans comprising: uniformly administering a therapeutically effective amount of a live low dose malaria vaccine to each individual within the target population on each of two or three consecutive days. The methods include using Plasmodium infected mosquitoes to inject Plasmodium into individuals through mosquito bites.

    ROADMAP FOR CONTROLLING MALARIA
    2.
    发明申请
    ROADMAP FOR CONTROLLING MALARIA 审中-公开
    控制疟疾的道路

    公开(公告)号：US20130295138A1

    公开(公告)日：2013-11-07

    申请号：US13997269

    申请日：2011-12-20

    申请人： Eng Hong Lee

    发明人： Eng Hong Lee

    IPC分类号： A61K39/015

    CPC分类号： A61K39/015 ,  A61K39/012 ,  A61K2039/545 ,  A61K2039/552

    摘要： Embodiments of the present invention concern methods of preventing malaria in a target population of humans comprising: uniformly administering a therapeutically effective amount of a live low dose malaria vaccine to each individual within the target population on each of two or three consecutive days. The methods include using Plasmodium infected mosquitoes to inject Plasmodium into individuals through mosquito bites.

    摘要翻译： 本发明的实施方案涉及预防人群目标群体中的疟疾的方法，其包括：在连续两天或连续三天中的每一天中，向目标群体内的每个个体均匀施用治疗有效量的活低剂量疟疾疫苗。 这些方法包括使用感染疟原虫的蚊子通过蚊子叮咬将疟原虫注入个体。

    METHOD OF PROTECTING AGAINST CHRONIC INFECTIONS
    3.
    发明申请
    METHOD OF PROTECTING AGAINST CHRONIC INFECTIONS 审中-公开
    保护慢性感染的方法

    公开(公告)号：US20070087021A1

    公开(公告)日：2007-04-19

    申请号：US11558894

    申请日：2006-11-10

    申请人： Eng-Hong Lee

    发明人： Eng-Hong Lee

    IPC分类号： A61K39/015 ,  A61K31/4706 ,  A61K31/4745

    CPC分类号： A61K39/012 ,  A61K31/4706 ,  A61K31/4745 ,  Y02A50/412

    摘要： The present invention is directed to a method of protecting an animal against against malaria caused by Plasmodium which undergoes more than one stage in its life cycle or undergoes more than one infectious cycle, the method comprising: a) administering to the animal a live vaccine containing sufficient Plasmodium sporozites that are low in pathogenicity and sensitive to one or more anti-malarial drugs to develop an immunological response in the animal; b) maintaining the animal free from anti-malarial drugs effective against Plasmodium for a period of time corresponding to about one life cycle or infectious cycle of the Plasmodium; and c) thereafter administering to the animal a anti-malarial drugs effective against Plasmodium for a period of time corresponding to at least one life cycle or infectious cycle of the Plasmodium.

    摘要翻译： 本发明涉及一种保护动物免于疟疾引起的疟疾的方法，其在其生命周期中经历多于一个阶段或经历多于一个感染循环，所述方法包括：a）向动物施用含有 足够的疟原虫孢子虫具有低致病性，并且对一种或多种抗疟药物敏感以在动物中发展免疫应答; b）保持动物免于抗疟疾药物有效对抗疟原虫的一个生命周期或感染周期的一段时间; 和c）之后向动物施用对抗疟原虫有效的抗疟疾药物，其时间对应于疟原虫的至少一个生命周期或感染周期。

    Method of protecting chronic infections
    4.
    发明申请
    Method of protecting chronic infections 审中-公开
    保护慢性感染的方法

    公开(公告)号：US20060093627A1

    公开(公告)日：2006-05-04

    申请号：US11295511

    申请日：2005-12-07

    申请人： Eng-Hong Lee

    发明人： Eng-Hong Lee

    IPC分类号： A61K39/012

    CPC分类号： A61K9/0056 ,  A61K39/012 ,  A61K47/36 ,  A61K2300/00

    摘要： The present invention is directed to a method of protecting an animal against a chronic disease, the disease being caused by an infectious organism which undergoes more than one stage in its life cycle or undergoes more than one infectious cycle. The method comprises: a) administering to the animal a live vaccine containing sufficient organisms to develop an immunological response in the animal; b) maintaining the animal free from chemotherapeutic agents effective against the infectious organism for a period of time corresponding to about one life or infectious cycle of the organism; and c) thereafter administering to the animal a chemotherapeutic agent effective against the infectious organism for a period of time corresponding to at least one life or infectious cycle of the infectious organism.

    摘要翻译： 本发明涉及一种保护动物免受慢性疾病的方法，该疾病由在其生命周期中经历多于一个阶段或经历多于一个感染周期的感染性生物引起。 该方法包括：a）向动物施用含有足够生物体的活疫苗以在动物中发展免疫应答; b）保持动物免受有效对抗传染性生物体的化学治疗剂相当于生物体的约一个寿命或感染循环的时间; 以及c）此后向所述动物施用对感染性生物有效的化学治疗剂，所述化学治疗剂对应于感染性生物的至少一个寿命或感染循环。

    Method of protecting against coccidiosis
    5.
    发明申请
    Method of protecting against coccidiosis 审中-公开
    防止球虫病的防治方法

    公开(公告)号：US20050226897A1

    公开(公告)日：2005-10-13

    申请号：US11149157

    申请日：2005-06-10

    申请人： Eng-Hong Lee

    发明人： Eng-Hong Lee

    IPC分类号： A61K45/00 ,  A61K9/00 ,  A61K39/012 ,  A61K47/36 ,  A61P31/00 ,  A61P33/02

    CPC分类号： A61K9/0056 ,  A61K39/012 ,  A61K47/36 ,  A61K2300/00

    摘要： In one aspect, the present invention is directed to a method of protecting a poultry bird against coccidiosis. The method comprises: a) administering to the bird a live vaccine containing sufficient number of Eimeria sp. to develop an immunological response in the animal; b) maintaining the animal free from chemotherapeutic agents effective against the Eimeria sp. for a period of time corresponding to about one life cycle or infectious cycle of the Eimeria sp.; and c) thereafter administering to the animal a therapeutic amount of a narasin ionophore for a period of time corresponding to at least one life cycle or infectious cycle of the Eimeria sp.

    摘要翻译： 一方面，本发明涉及一种保护禽鸟抗球虫病的方法。 所述方法包括：a）向所述鸟施用含有足够数量的艾美球虫的活疫苗。 在动物中发展免疫反应; b）保持动物免于对艾美球虫有效的化学治疗剂。 一段时间对应于艾美球虫的约一个生命周期或感染周期。 以及c）此后向所述动物施用治疗量的Narasin离子载体，所述时间对应于艾美球虫的至少一个生命周期或感染循环。

    Drinking tray for small animals shipped in containers
    6.
    发明授权
    Drinking tray for small animals shipped in containers 失效
    小容器的饮水盘运送在集装箱中

    公开(公告)号：US5588395A

    公开(公告)日：1996-12-31

    申请号：US43488

    申请日：1993-04-06

    申请人： Eng-Hong Lee

    发明人： Eng-Hong Lee

    IPC分类号： A01K7/00 ,  A01K39/02 ,  A01K45/00

    CPC分类号： A01K45/005 ,  A01K39/02 ,  A01K7/00

    摘要： The present invention provides for a drinking tray for use by small animals. The drinking tray has at least two fluid containment regions mounted on a common base, the fluid containment regions being separated one from another by elongate openings extending across the tray. In an aspect of the invention there is provided a drinking tray for use in a shipping container for transport of small animals, the shipping container being divided into sections by removable dividers. The drinking tray has a plurality of fluid containment regions mounted on a common base for providing stability. The tray is provided with openings for accepting the inserts which divide the shipping cartons into sections, the openings separating the fluid containment regions one from another such that each section of the shipping carton will be provided with a fluid containment region. Each section of the tray is provided with a fluid holding portion having a capacity to hold sufficient fluid to prevent the dehydration of the animals in the section of the shipping tray during transport.

    摘要翻译： 本发明提供一种用于小型动物的饮用盘。 饮用盘具有至少两个安装在公共基座上的流体容纳区域，流体容纳区域通过延伸穿过托盘的细长开口相互分离。 在本发明的一个方面，提供了一种用于运输小型动物的运输集装箱的饮用盘，该运输容器通过可拆卸的分配器分成多个部分。 饮用盘具有多个安装在公共基座上的流体容纳区，用于提供稳定性。 托盘设置有开口，用于接收将运输纸箱分成多个部分的插入件，开口将流体容纳区域彼此分开，使得运输纸箱的每个部分将设置有流体容纳区域。 托盘的每个部分设置有流体保持部分，其具有保持足够的流体的能力，以防止运输期间运输托盘的部分中的动物脱水。

    DEVICE FOR TESTING THE EFFECTIVENESS OF DISINFECTANTS ON PROTOZOAN PARASITES
    7.
    发明申请
    DEVICE FOR TESTING THE EFFECTIVENESS OF DISINFECTANTS ON PROTOZOAN PARASITES 审中-公开
    用于测试消毒剂对原生动物寄生虫有效性的装置

    公开(公告)号：US20080171355A1

    公开(公告)日：2008-07-17

    申请号：US11939182

    申请日：2007-11-13

    申请人： ENG-HONG LEE

    发明人： ENG-HONG LEE

    IPC分类号： C12Q1/22 ,  C12M1/00

    CPC分类号： C12Q1/22 ,  G01N2333/44 ,  G01N2333/455

    摘要： This invention relates to a device for testing the efficacy of any disinfectant treatment, such as water disinfectants or equipment disinfectants. The device includes a culture of live unsporulated free-living protozoan parasites. If the disinfectant treatment successfully kills all or a substantial number of parasites, then the treatment is effective. One can determine whether the parasites have been killed or not by exposing them to sporulation conditions, and if they sporulate after exposure to the disinfectant treatment, then they were not killed by the disinfectant treatment.

    摘要翻译： 本发明涉及一种用于测试任何消毒剂处理功效的装置，例如水消毒剂或设备消毒剂。 该装置包括活的未分配的自由生物原生动物寄生虫的文化。 如果消毒剂治疗成功地杀死了所有或大量的寄生虫，那么治疗是有效的。 可以通过将它们暴露于孢子形成条件来确定寄生虫是否已经被杀死，并且如果它们在暴露于消毒剂处理之后形成孢子，则它们不被消毒剂处理杀死。

    Method of protecting against chronic infections
    8.
    发明授权
    Method of protecting against chronic infections 失效
    防止慢性感染的方法

    公开(公告)号：US06306385B1

    公开(公告)日：2001-10-23

    申请号：US09062316

    申请日：1998-04-20

    申请人： Eng-Hong Lee

    发明人： Eng-Hong Lee

    IPC分类号： A01N6300

    CPC分类号： A61K9/0056 ,  A61K39/012 ,  A61K47/36 ,  A61K2300/00

    摘要： The present invention is directed to a method of protecting an animal against a chronic disease, the disease being caused by an infectious organism which undergoes more than one life cycle. The method comprises: a) administering to the animal a vaccine containing sufficient organisms to develop an immunological response in the animal; b) maintaining the animal free from chemotherapeutic agents effective against the infectious organism for a period of time corresponding to about one life cycle of the organism; and c) thereafter administering to the animal a chemotherapeutic agent effective against the infectious organism for a period of time corresponding to at least one life cycle of the infectious organism.

    摘要翻译： 本发明涉及一种保护动物免受慢性疾病的方法，该疾病由经历多于一个生命周期的感染性生物引起。 该方法包括：a）向动物施用含有足够生物体以在动物中产生免疫应答的疫苗; b）保持动物免受化学治疗剂有效对抗感染性生物体的时间相当于约一个生命周期 有机体 和），然后向所述动物施用对感染性生物有效的化学治疗剂，所述化学治疗剂对应于感染性生物的至少一个生命周期。

    Soft gel delivery system for treating poultry
    10.
    发明授权
    Soft gel delivery system for treating poultry 有权
    用于处理家禽的软胶体递送系统

    公开(公告)号：US08794185B2

    公开(公告)日：2014-08-05

    申请号：US11793047

    申请日：2005-04-14

    申请人： Eng-Hong Lee

    发明人： Eng-Hong Lee

    IPC分类号： A01K39/00 ,  A01K45/00 ,  A61D1/02 ,  A61D7/00

    CPC分类号： A61K39/012 ,  A01K39/01 ,  A01K45/00 ,  A01K45/002 ,  A01K45/007 ,  A61D1/025 ,  A61D7/00 ,  A61K9/06 ,  A61K39/002 ,  A61K45/06 ,  A61K47/36 ,  A61K2039/52 ,  A61K2039/54 ,  A61K2039/542 ,  A61K2039/552 ,  A61K2039/70

    摘要： The present invention is directed to a method of treating poultry hatchlings in a hatchling tray. The method comprises of providing a soft gel form capable of being dispensed through a spray nozzle, providing a spray dispensing apparatus, the apparatus being capable of delivering a predetermined volume of the gel as a plurality of small beadlets through a plurality of nozzles, placing the hatchling tray containing the hatchlings beneath the nozzles of the dispensing apparatus, dispensing the predetermined volume of the soft gel containing the therapeutic agent as small beadlets into the hatchling tray and allowing the hatchlings to consume the beadlets. The pre sent invention is also directed to a dispensing apparatus for dispensing a therapeutic agent in a soft gel into a hatchling tray of poultry hatchlings.

    摘要翻译： 本发明涉及一种在孵化盘中处理家禽幼体的方法。 该方法包括提供能够通过喷嘴分配的软凝胶形式，提供喷雾分配装置，该装置能够通过多个喷嘴将预定体积的凝胶作为多个小珠粒递送， 将分配装置的喷嘴下面的小型幼稚园的幼体托盘分配给小型小珠的预定体积的含有作为小珠粒的治疗剂的软凝胶，并允许幼体消耗小珠。 本发明还涉及一种用于将软凝胶中的治疗剂分配到家禽幼体的孵化盘中的分配装置。