摘要:
A method of treating cancer or metastasis is provided involving administering at least one oncostatin M (OSM) antagonist to a subject, wherein the subject has been diagnosed with cancer. Administration of an OSM antagonist such as a small molecule pharmaceutical is provided as well as an anti-OSM antibody, an anti-OSM aptamer, and an OSM mRNA antagonist. The OSM antagonists were found to inhibit or prevent tumor cell detachment, proliferation and metastasis in several cancer types.
摘要:
A method of treating cancer or metastasis is provided involving administering at least one oncostatin M (OSM) antagonist to a subject, wherein the subject has been diagnosed with cancer. Administration of an OSM antagonist such as a small molecule pharmaceutical is provided as well as an anti-OSM antibody, an anti-OSM aptamer, and an OSM mRNA antagonist. The OSM antagonists were found to inhibit or prevent tumor cell detachment, proliferation and metastasis in several cancer types.
摘要:
The present disclosure provides a convertor for X-ray radiography and its manufacturing method and an X-ray detector, wherein the surface of the scintillator facing the X-ray is covered with photonic crystals of a two-dimensional or three-dimensional spatial structure capable of reflecting the visible light facing the photonic crystals generated by the scintillator to increase the intensity of the output light of the scintillator by more than 100%, thus enhancing the image brightness and improving the image resolution, in addition to reducing to a certain extent the interference between pixels due to the ability of the photonic crystals to control the direction of the light being reflected, for example, by controlling the reflecting direction so as to be vertical to the surface of the scintillator, and the manufacturing method and material for the photonic crystals are low in cost without toxicity, enabling it to be used more widely.
摘要:
Disclosed herein are the methods to improve the electrical conductivity for micro-moulded plastic parts containing carbon nanotubes. The polymer/carbon nanotubes composites suitable for polymer micromoulding including 80˜99.95 wt % of a polymer pellet or powder, 0-2 wt % of antioxidant, 0-2 wt % of dispersant agent and 0.05-20 wt % of carbon nanotube with a diameter 0.5-200 nm and a length of 200 nm-20 μm are firstly prepared through melt extrusion. The plastic microparts are prepared by micromoulding of the polymer/carbon nanotubes composites including micro extrusion, micro injection and hot embossing at optimized processing conditions and then are subject to a post thermal treatment to enhance the electrical conductivity. The post thermal treatment methods include electric heating, microwave, infrared or plasma heating. The methods disclosed can be used to prepare electrical conductive biomedical implanted plastic micro devices for minimally invasive surgery, biomedical sensors, microelectrodes, drug delivery devices, automated pipetting systems, breathing tubes, EMI devices etc.
摘要:
The invention discloses a security configuration verification device for performing a security configuration verification on a network device, which comprises: one or more preconfigured scanning policies; a scanning policy generator, which selects a scanning policy from the one or more preconfigured scanning policies to generate a new scanning policy corresponding to the network device; and a scanner, which performs the security scanning on the network device with the generated new scanning policy and thereby performs the security configuration verification. The invention also discloses a corresponding security configuration verification method and a network system employing the verification device.
摘要:
The present disclosure provides a convertor for X-ray radiography and its manufacturing method and an X-ray detector, wherein the surface of the scintillator facing the X-ray is covered with photonic crystals of a two-dimensional or three-dimensional spatial structure capable of reflecting the visible light facing the photonic crystals generated by the scintillator to increase the intensity of the output light of the scintillator by more than 100%, thus enhancing the image brightness and improving the image resolution, in addition to reducing to a certain extent the interference between pixels due to the ability of the photonic crystals to control the direction of the light being reflected, for example, by controlling the reflecting direction so as to be vertical to the surface of the scintillator, and the manufacturing method and material for the photonic crystals are low in cost without toxicity, enabling it to be used more widely.
摘要:
Gene expression is controlled at the transcriptional level by very diverse group of proteins called transcription factors (TFs). 5671 soybean (Glycine max) genes have been identified and disclosed as putative transcription factors through mining of soybean genome sequences. Distinct classes of the TFs are also disclosed which may be expressed and or function in a manner that is tissue specific, developmental stage specific, biotic and/or abiotic stress specific. Manipulation and/or genetic engineering of specific transcription factors may improve the agronomic performance or nutritional quality of plants. Transgenic plants expressing a select number of these TFs are disclosed. These transgenic plants show some promising traits, such as improving the capability of the plant to grow and reproduce under drought conditions.
摘要:
A method for fabricating ultra-short T-gates on heterojunction field effect transistors (HFETs) comprising the steps of (a) providing a coating of three layers of resists, with polymethylmethacrylate (PMMA) with high molecular weight on the bottom, polydimethylglutarimide (PMGI) in the middle, and PMMA with low molecular weight on the top; (b) in a first exposure, exposing and developing the layers with a dose of a developer that is high enough to allow the developer to break the top PMMA but low to avoid contributing significantly to the overall dose received in the bottom PMMA layer; and (c) in a second exposure, using an exposure and developing process to define 0.03-0.05 um openings in the bottom PMMA layer.