公开(公告)号：US09205204B2

公开(公告)日：2015-12-08

申请号：US13567995

申请日：2012-08-06

Applicant: Mahalaxmi Gita Bangera ,  Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Robert Langer ,  Eric C. Leuthardt ,  Stephen L. Malaska ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Sharon L. Wolda ,  Lowell L. Wood, Jr.

Inventor： Mahalaxmi Gita Bangera ,  Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Robert Langer ,  Eric C. Leuthardt ,  Stephen L. Malaska ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Sharon L. Wolda ,  Lowell L. Wood, Jr.

IPC: A61M5/00 ,  A61M5/42 ,  A61M5/46 ,  A61B17/34 ,  G06F17/50 ,  A61B19/00

CPC classification number: A61B34/10 ,  A61B17/3403 ,  A61B2017/3411 ,  A61B2034/108 ,  A61B2090/363 ,  A61M5/422 ,  A61M5/427 ,  A61M5/46 ,  A61M2205/13 ,  A61M2207/00 ,  A61M2210/0606 ,  B29C64/386 ,  B33Y50/02 ,  B33Y80/00 ,  G05B19/4099 ,  G05B2219/35134 ,  G05B2219/49007 ,  G06F17/5086

Abstract: Wearable injection guides and manufacture and use thereof are described, which include: a rigid needle-penetrable material having an inner surface and an outer surface, the inner surface having form-fitting contours substantially conforming to a topography of a body region of an individual and the outer surface including one or more fiducials indication of at least one treatment parameter.

Abstract translation: 描述了可穿戴式注射引导件及其制造和使用，其包括：具有内表面和外表面的刚性可针穿透材料，内表面具有基本上符合个人身体区域的形貌的形状配合轮廓， 所述外表面包括至少一个治疗参数的一个或多个基准指示。

公开(公告)号：US09180280B2

公开(公告)日：2015-11-10

申请号：US12581295

申请日：2009-10-19

Applicant: Daniel Hawkins ,  John M. Adams

Inventor： Daniel Hawkins ,  John M. Adams

IPC: A61M25/10 ,  A61B17/22 ,  A61B17/3207 ,  A61B17/225

CPC classification number: A61M25/1006 ,  A61B17/2202 ,  A61B17/22022 ,  A61B17/22029 ,  A61B17/2256 ,  A61B17/320725 ,  A61B2017/22024 ,  A61B2017/22082 ,  A61B2017/22088 ,  A61M25/104 ,  A61M2025/105 ,  A61M2025/1086

Abstract: A catheter comprises an elongated carrier and a balloon carried by the carrier in sealed relation thereto. The balloon has an outer surface and is arranged to receive a fluid therein that inflates the balloon. The catheter further comprises a shock wave generator within the balloon that forms mechanical shock waves within the balloon, and a medicinal agent carried on the outer surface of the balloon. The medicinal agent is releasable from the balloon by the shock waves.

Abstract translation: 导管包括细长的载体和由载体以与其密封的关系承载的气囊。 气囊具有外表面并且被布置成接收其中使气囊膨胀的流体。 该导管还包括气囊内的冲击波发生器，其在球囊内形成机械冲击波，以及携带在气球的外表面上的药剂。 药剂通过冲击波从气囊释放。

公开(公告)号：US20150168654A1

公开(公告)日：2015-06-18

申请号：US14569107

申请日：2014-12-12

Applicant: Jonathan Hatcher Hatcher ,  Justin Kretschmar ,  Alan McCleary ,  Corey Williams ,  Daniel Hawkins

Inventor： Jonathan Hatcher Hatcher ,  Justin Kretschmar ,  Alan McCleary ,  Corey Williams ,  Daniel Hawkins

IPC: G02B6/38

CPC classification number: G02B6/3816 ,  G02B6/3826 ,  G02B6/506

Abstract: The present invention provides optical connectors and optical feedthrough systems that can be mated and unmated in a harsh environment, such as underwater, and is particularly concerned with a method and apparatus for securing and sealing an optical feedthrough or connector from the surrounding turbid environment.

Abstract translation: 本发明提供了可以在诸如水下的恶劣环境下配合和不配合的光学连接器和光学馈通系统，并且特别涉及用于将光学馈通或连接器从周围的混浊环境中固定和密封的方法和装置。

公开(公告)号：US09044619B2

公开(公告)日：2015-06-02

申请号：US13207381

申请日：2011-08-10

Applicant: Daniel Hawkins ,  John M. Adams

Inventor： Daniel Hawkins ,  John M. Adams

IPC: A61B17/22 ,  A61N1/38 ,  A61M25/10 ,  A61N1/05

CPC classification number: A61B17/22022 ,  A61B2017/22025 ,  A61B2017/22054 ,  A61B2017/22061 ,  A61B2017/22062 ,  A61B2017/22068 ,  A61B2017/22098 ,  A61M25/1002 ,  A61M2025/1072 ,  A61N1/056 ,  A61N1/38

Abstract: A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves. The shock waves propagate through the liquid and impinge upon the valve to decalcify and open the valve.

Abstract translation: 瓣膜成形术系统包括适于邻近瓣膜的小叶放置的球囊。 气球用液体充气。 该系统还包括产生冲击波的球囊内的冲击波发生器。 冲击波通过液体传播并撞击阀门以脱钙并打开阀门。

公开(公告)号：US08758308B2

公开(公告)日：2014-06-24

申请号：US11705811

申请日：2007-02-12

Applicant: Clifton A. Alferness ,  John M. Adams ,  Daniel Hawkins

Inventor： Clifton A. Alferness ,  John M. Adams ,  Daniel Hawkins

IPC: A61M5/31

CPC classification number: A61M5/1452 ,  A61M5/1408 ,  A61M5/14248 ,  A61M5/14526 ,  A61M5/1454 ,  A61M5/16881 ,  A61M2005/1405 ,  A61M2005/1426 ,  A61M2005/1585 ,  A61M2005/1587 ,  A61M2025/0266

Abstract: A disposable infusion device comprises a base arranged to adhere to a patient's skin, a cannula arranged to extend from the base to beneath the patient's skin to deliver a liquid medicament to the patient, and a source arranged to provide the cannula with a liquid medicament. The source includes a compressible tube that pumps the liquid medicament to the cannula.

Abstract translation: 一次性输注装置包括布置成粘附到患者皮肤的基部，布置成从基部延伸到患者皮肤下方以将液体药物递送到患者的插管，以及布置成为套管提供液体药物的源。 源包括将液体药物泵送到套管的可压缩管。

公开(公告)号：US20130338770A1

公开(公告)日：2013-12-19

申请号：US13495275

申请日：2012-06-13

Applicant: Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

Inventor： Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC: A61F2/12

CPC classification number: A61F2/12 ,  A61B5/076 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/14735

Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; a plurality of sensor modules attached to the shell, the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, the sensor modules positioned at a distance from each other, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.

Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 至少一个流体可透过的盖，所述盖完全包围所述壳; 多个传感器模块，其附接到所述壳体，所述传感器模块定向成检测所述壳体和所述盖子之间的流体中的一种或多种分析物，所述传感器模块彼此间隔一定距离，其中所述多个传感器模块中的每一个包括 唯一标识符; 以及可操作地附接到所述多个传感器模块的至少一个电源。

公开(公告)号：US20130338768A1

公开(公告)日：2013-12-19

申请号：US13495212

申请日：2012-06-13

Applicant: Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

Inventor： Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC: A61F2/12

CPC classification number: A61F2/12

Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of sensor modules attached to the shell, the sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, the sensor modules positioned at a distance from each other, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.

Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 多个传感器模块，其附接到壳体，所述传感器模块被定向成检测邻近所述壳体的流体中的一种或多种分析物，所述传感器模块相互间隔一定距离，其中所述多个传感器模块中的每一个包括唯一的 标识符 以及可操作地附接到所述多个传感器模块的至少一个电源。

公开(公告)号：US08409151B2

公开(公告)日：2013-04-02

申请号：US13024618

申请日：2011-02-10

Applicant: Daniel Hawkins ,  Brett J. Carter ,  John M. Adams

Inventor： Daniel Hawkins ,  Brett J. Carter ,  John M. Adams

IPC: A61M5/00

CPC classification number: A61M5/158 ,  A61M5/14248 ,  A61M2005/1585 ,  A61M2205/583 ,  A61M2209/045

Abstract: An infusion system includes a disposable wearable infusion device and a filler device. The disposable infusion device has a body arranged to be adhered to a patient's skin and a reservoir for holding a liquid medicant to be infused into the patient. The filler device is arranged to detachably receive the infusion device body and to transfer a volume of the liquid medicant to the infusion device reservoir. The filler device may be part of a service device arranged to detachably receive the infusion device and which also includes a cannula driver and a cannula for providing the infusion device with a cannula and deploying the cannula to beneath a patient's skin.

Abstract translation: 输液系统包括一次性佩戴式输液装置和填充装置。 一次性输注装置具有被布置成粘附到患者皮肤的本体和用于保持待注入患者体内的液体药剂的储存器。 填充装置布置成可拆卸地接收输注装置主体并将一定体积的液体药剂输送到输注装置储存器。 填充装置可以是布置成可拆卸地接收输注装置并且还包括插管驱动器和套管的服务装置的一部分，用于为输注装置提供插管并将插管展开到患者皮肤下方。

公开(公告)号：US20120203255A1

公开(公告)日：2012-08-09

申请号：US13267383

申请日：2011-10-06

Applicant: DANIEL HAWKINS ,  John M. Adams ,  Tom Goff

Inventor： DANIEL HAWKINS ,  John M. Adams ,  Tom Goff

IPC: A61B17/22

CPC classification number: A61B17/2202 ,  A61B17/22022 ,  A61B2017/22025 ,  A61B2017/22062 ,  A61B2017/22065

Abstract: A system and method for breaking obstructions in body lumens includes a catheter including an elongated carrier, a balloon at one end of the carrier in sealed relation thereto, the carrier including a channel arranged to receive a fluid that fills and pressurizes the balloon to an internal pressure of greater than two atmospheres, and an arc generator including at least one electrode within the balloon that forms a mechanical shock wave within the balloon. The system further includes a power source that provides electrical energy to the arc generator.

Abstract translation: 用于破坏体腔内的障碍物的系统和方法包括导管，其包括细长的载体，与所述载体的密封关系的一端处的气囊，所述载体包括通道，所述通道被布置成接收将气囊填充并加压到内部 大于2个大气压的压力，以及包括球囊内的至少一个电极的电弧发生器，其在球囊内形成机械冲击波。 该系统还包括向电弧发生器提供电能的电源。

公开(公告)号：US20120165917A1

公开(公告)日：2012-06-28

申请号：US13397952

申请日：2012-02-16

Applicant: Stefan Schreck ,  Daniel Hawkins

Inventor： Stefan Schreck ,  Daniel Hawkins

IPC: A61F2/06

CPC classification number: A61F2/07 ,  A61F2/2412 ,  A61F2/856 ,  A61F2/89 ,  A61F2/90 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2250/0024

Abstract: Some embodiments are directed to a stent graft comprising a first stent graft having a first and a second stent and a first and a second inner graft supported by the first stent, and an outer graft. The second inner graft can be spaced apart from the first inner graft so that a portion of the first stent is not covered by either the first inner graft or the second inner graft. A first and second portion of the outer graft can be attached to the first stent, the outer graft being unsupported by the stent between the first and second portions so as to form a fillable space between the outer graft, the first inner graft, and the second inner graft. Some embodiments further comprise a second stent graft deployable within the inside of the first stent graft to sealingly cover the uncovered portion of the first stent.

Abstract translation: 一些实施例涉及包括具有第一和第二支架的第一支架移植物和由第一支架支撑的第一和第二内部移植物以及外部移植物的支架移植物。 第二内部移植物可以与第一内部移植物间隔开，使得第一支架的一部分不被第一内部移植物或第二内部移植物覆盖。 外部移植物的第一和第二部分可以附接到第一支架，外部移植物在第一和第二部分之间不被支架支撑，以便在外部移植物，第一内部移植物和第二部分之间形成可填充的空间 第二内移植物。 一些实施例还包括可展开在第一支架移植物内部的第二支架移植物，以密封地覆盖第一支架的未覆盖部分。