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公开(公告)号：US20120244175A1
公开(公告)日：2012-09-27
申请号：US13472035
申请日：2012-05-15
申请人： Teresa Elisa Virginia CABEZON-SILVA , Jean-Pol Cassart , Thierry Coche , Swann Romain Jean-Thomas Gaulis , Carlota Vinals Y De Bassols
发明人： Teresa Elisa Virginia CABEZON-SILVA , Jean-Pol Cassart , Thierry Coche , Swann Romain Jean-Thomas Gaulis , Carlota Vinals Y De Bassols
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , C07K14/82
摘要： CASB7439 polypeptides and polynucleotides, immunogenic compositions comprising them and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB7439 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly colorectal cancers, autoimmune diseases, and related conditions.
摘要翻译： 公开了CASB7439多肽和多核苷酸，包含它们的免疫原性组合物和通过重组技术产生此类多肽的方法。 还公开了在诊断中使用CASB7439多肽和多核苷酸的方法，以及用于预防和治疗癌症，特别是结肠直肠癌，自身免疫疾病和相关病症的疫苗。
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公开(公告)号：US07811574B2
公开(公告)日：2010-10-12
申请号：US10650608
申请日：2003-08-28
申请人： Jean-Pol Cassart , Teresa Elisa Virginia Cabezon-Silva , Thierry Coche , Swann Romain Jean-Thomas Gaulis , Carlota Vinals Y De Bassols
发明人： Jean-Pol Cassart , Teresa Elisa Virginia Cabezon-Silva , Thierry Coche , Swann Romain Jean-Thomas Gaulis , Carlota Vinals Y De Bassols
IPC分类号： A61K39/00
CPC分类号： C07K14/82 , A61K39/00 , C07K14/4748
摘要： CASB7439 polypeptides and polynucleotides, immunogenic compositions comprising them and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB7439 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly colorectal, breast, and lung cancers, autoimmune diseases, and related conditions.
摘要翻译： 公开了CASB7439多肽和多核苷酸，包含它们的免疫原性组合物和通过重组技术产生这种多肽的方法。 还公开了用于诊断中的CASB7439多肽和多核苷酸的方法，以及用于预防和治疗癌症特别是结肠直肠癌，乳腺癌和肺癌，自身免疫疾病和相关病症的疫苗。
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公开(公告)号：US20060269532A1
公开(公告)日：2006-11-30
申请号：US11344932
申请日：2006-02-01
申请人： Jiangchun Xu , Davin Dillon , Jennifer Mitcham , Susan Harlocker , Yuqiu Jiang , Robert Henderson , Michael Kalos , Gary Fanger , Marc Retter , John Stolk , Craig Day , Thomas Vedvick , Darrick Carter , Samuel Li , Aijun Wang , Yasir Skeiky , William Hepler , John Hural , Patricia McNeill , Raymond Houghton , Carlota Vinals y de Bassols , Teresa Foy , Yoshihiro Watanabe , Madeleine Meagher , Ta Deng
发明人： Jiangchun Xu , Davin Dillon , Jennifer Mitcham , Susan Harlocker , Yuqiu Jiang , Robert Henderson , Michael Kalos , Gary Fanger , Marc Retter , John Stolk , Craig Day , Thomas Vedvick , Darrick Carter , Samuel Li , Aijun Wang , Yasir Skeiky , William Hepler , John Hural , Patricia McNeill , Raymond Houghton , Carlota Vinals y de Bassols , Teresa Foy , Yoshihiro Watanabe , Madeleine Meagher , Ta Deng
CPC分类号： C07K14/4748 , A61K2039/505 , C07K16/3069 , C07K2317/34 , C12Q1/68 , C12Q1/6886 , G01N33/57434
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
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公开(公告)号：US20110052615A1
公开(公告)日：2011-03-03
申请号：US12860020
申请日：2010-08-20
申请人： TERESA ELISA VIRGINIA CABEZON-SILVA , JEAN-POL CASSART , THIERRY COCHE , SWANN ROMAIN JEAN-THOMAS GAULIS , CARLOTA VINALS Y DE BASSOLS
发明人： TERESA ELISA VIRGINIA CABEZON-SILVA , JEAN-POL CASSART , THIERRY COCHE , SWANN ROMAIN JEAN-THOMAS GAULIS , CARLOTA VINALS Y DE BASSOLS
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , C07K14/82
摘要： CASB7439 polypeptides and polynucleotides, immunogenic compositions comprising them and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB7439 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly colorectal cancers, autoimmune diseases, and related conditions.
摘要翻译： 公开了CASB7439多肽和多核苷酸，包含它们的免疫原性组合物和通过重组技术产生此类多肽的方法。 还公开了在诊断中使用CASB7439多肽和多核苷酸的方法，以及用于预防和治疗癌症，特别是结肠直肠癌，自身免疫疾病和相关病症的疫苗。
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公开(公告)号：US07439320B2
公开(公告)日：2008-10-21
申请号：US10362597
申请日：2001-08-20
IPC分类号： A61K38/00
CPC分类号： C07K14/475 , A61K38/00 , A61K39/00 , A61K39/0011 , A61K2039/5158 , A61K2039/53 , C07K2319/00
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung, colon, colorectal and breast cancer, are disclosed. Illustrative compositions comprise one or more Cripto tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung, colon, colorectal and breast cancer.
摘要翻译： 公开了用于治疗和诊断癌症，特别是肺癌，结肠癌，结肠直肠癌和乳腺癌的组合物和方法。 说明性组合物包含一个或多个Cripto肿瘤多肽，其免疫原性部分，编码此类多肽的多核苷酸，表达此类多肽的抗原呈递细胞，以及对表达此类多肽的细胞特异的T细胞。 所公开的组合物可用于例如疾病，特别是肺，结肠，结肠直肠和乳腺癌的诊断，预防和/或治疗。
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公开(公告)号：US07033827B2
公开(公告)日：2006-04-25
申请号：US10144678
申请日：2002-05-09
申请人： Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Robert A. Henderson , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler , John Hural , Patricia D. McNeill , Raymond L. Houghton , Carlota Vinals y de Bassols , Teresa M. Foy , Yoshihiro Watanabe , Madeleine Joy Meagher , Ta Deng
发明人： Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Robert A. Henderson , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler , John Hural , Patricia D. McNeill , Raymond L. Houghton , Carlota Vinals y de Bassols , Teresa M. Foy , Yoshihiro Watanabe , Madeleine Joy Meagher , Ta Deng
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2035/124 , A61K2039/505 , A61K2039/5156 , A61K2039/53 , C07K14/47 , C07K14/4748 , C07K14/705 , C07K16/3069 , C07K2317/34 , C07K2319/00 , C12N9/6424 , C12N2710/14143 , C12N2760/16022
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
摘要翻译： 公开了用于治疗和诊断癌症，特别是前列腺癌的组合物和方法。 说明性组合物包含一种或多种前列腺特异性多肽，其免疫原性部分，编码此类多肽的多核苷酸，表达此类多肽的抗原呈递细胞，以及对表达此类多肽的细胞特异的T细胞。 所公开的组合物可用于例如疾病，特别是前列腺癌的诊断，预防和/或治疗。
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公开(公告)号：US20060052593A1
公开(公告)日：2006-03-09
申请号：US11199820
申请日：2005-08-09
CPC分类号： C07K14/47 , A61K39/00 , A61K2039/5154 , A61K2039/55561 , A61K2039/57 , C07K2319/00
摘要： CASB618 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB618 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly ovarian and colon cancers, autoimmune diseases, and related conditions.
摘要翻译： 公开了CASB618多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还公开了在诊断中使用CASB618多肽和多核苷酸的方法，以及用于癌症，特别是卵巢和结肠癌，自身免疫疾病和相关病症的预防和治疗性治疗的疫苗。
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公开(公告)号：US06943236B2
公开(公告)日：2005-09-13
申请号：US10012896
申请日：2001-12-10
申请人： Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler , Robert A. Henderson , John Hural , Patricia D. McNeill , Raymond L. Houghton , Carlota Vinals y de Bassols , Teresa M. Foy , Yoshihiro Watanabe , Madeleine Joy Meagher
发明人： Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler , Robert A. Henderson , John Hural , Patricia D. McNeill , Raymond L. Houghton , Carlota Vinals y de Bassols , Teresa M. Foy , Yoshihiro Watanabe , Madeleine Joy Meagher
IPC分类号： A61K35/12 , A61K38/00 , A61K39/00 , A61K48/00 , C07K14/11 , C07K14/47 , C07K14/705 , C07K16/30 , C12N9/64 , C07K14/00 , C07H21/02 , C12Q1/68 , C12N1/20
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2035/124 , A61K2039/505 , A61K2039/5156 , A61K2039/53 , C07K14/47 , C07K14/4748 , C07K14/705 , C07K16/3069 , C07K2317/34 , C07K2317/73 , C07K2319/00 , C12N9/6424 , C12N2760/16022
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
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公开(公告)号：US08207123B2
公开(公告)日：2012-06-26
申请号：US12860020
申请日：2010-08-20
申请人： Teresa Elisa Virginia Cabezon-Silva , Jean-Pol Cassart , Thierry Coche , Swann Romain Jean-Thomas Gaulis , Carlota Vinals Y De Bassols
发明人： Teresa Elisa Virginia Cabezon-Silva , Jean-Pol Cassart , Thierry Coche , Swann Romain Jean-Thomas Gaulis , Carlota Vinals Y De Bassols
IPC分类号： A61K38/00
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , C07K14/82
摘要： CASB7439 polypeptides and polynucleotides, immunogenic compositions comprising them and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB7439 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly colorectal cancers, autoimmune diseases, and related conditions.
摘要翻译： 公开了CASB7439多肽和多核苷酸，包含它们的免疫原性组合物和通过重组技术产生此类多肽的方法。 还公开了在诊断中使用CASB7439多肽和多核苷酸的方法，以及用于预防和治疗癌症，特别是结肠直肠癌，自身免疫疾病和相关病症的疫苗。
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10.发明申请BASB027 PROTEINS AND GENES FROM MORAXELLA CATARRHALIS, ANTIGENS, ANTIBODIES, AND USES 审中-公开来自MORAXELLA CATARRHALIS，抗原，抗体和用途的BASB027蛋白质和基因公开(公告)号：US20100143412A1
公开(公告)日：2010-06-10
申请号：US12621280
申请日：2009-11-18
CPC分类号： C07K14/212 , A61K39/00 , C07K2319/00
摘要： The invention provides BASB027 polypeptides and polynucleotides encoding BASB027 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
摘要翻译： 本发明提供BASB027多肽和编码BASB027多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供诊断，预防和治疗用途。
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