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公开(公告)号：US20170332904A1
公开(公告)日：2017-11-23
申请号：US15612066
申请日：2017-06-02
发明人： John Gannon , Matt Ream , Gary R. Tucholski
CPC分类号： A61B5/0008 , A61B5/0024 , A61B5/01 , A61B5/6833 , A61B5/6898 , A61B5/743 , A61B2562/166
摘要： An actively-powered temperature data logger patch with wireless data communication includes a sealed, flexible battery configured to provide continuous electrical power, and a flexible circuit including a microprocessor, a temperature sensor configured to sense a temperature of a target subject, a wireless communication transmitter and an antenna. In one example, the temperature sensor is located at a first end of the patch, and the antenna is located at an opposite, second end of the patch. The patch is configured to conform to a curved surface of the target subject and includes an adhesive configured to be removably applied to skin of the patient. An external computing device is capable of receiving communication from the wireless communication transmitter of the patch via an electromagnetic field.
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公开(公告)号：US09444078B2
公开(公告)日：2016-09-13
申请号：US14091981
申请日：2013-11-27
发明人： Gary R. Tucholski
CPC分类号： H01M2/0215 , H01M4/08 , H01M4/12 , H01M4/70 , H01M6/045 , H01M6/06 , H01M6/40 , H01M6/46 , H01M2300/0005 , H01M2300/0014
摘要： A flexible battery includes at least one electrochemical cell for generating an electrical current, including a cathode collector layer, a cathode layer, an anode layer, and an optional anode collector layer, some or all of which are formed of a dried or cured ink. A first substrate includes a pair of opposed side portions. A first electrode contact is provided that is electrically coupled to the cathode collector layer and is disposed along one of the pair of opposed side portions of the first substrate, and a second electrode contact is provided that is electrically coupled to the anode layer and is disposed along the other of the pair of opposed side portions of the first substrate. The cathode collector layer includes a geometry having a height and a width such that the number of squares is approximately 5 or less.
摘要翻译： 柔性电池包括用于产生电流的至少一个电化学电池，包括阴极集电器层，阴极层，阳极层和任选的阳极集电器层，其中一些或全部由干燥或固化的油墨形成。 第一基板包括一对相对的侧部。 提供第一电极接触件，其电耦合到阴极集电器层并且沿着第一衬底的一对相对侧部分中的一个设置，并且提供电耦合到阳极层的第二电极接触件，并且被布置 沿着第一基板的一对相对侧部分中的另一个。 阴极集电体层包括几何形状，其高度和宽度使得正方形的数量约为5或更小。
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公开(公告)号：US20130323565A1
公开(公告)日：2013-12-05
申请号：US13899291
申请日：2013-05-21
发明人： Gary R. Tucholski
IPC分类号： H01M6/40
CPC分类号： H01M6/40 , H01M2/0222 , H01M2/08 , H01M2/204 , H01M2/361 , H01M6/42 , H01M10/0427 , H01M10/285 , H01M10/365 , H01M12/085 , Y02E60/128
摘要： A flexible battery includes a first substrate layer with a first cell portion, a second cell portion, and a bridge portion connecting the first and second cell portions. An electrical bridge electrically couples a first electrochemical cell to a second electrochemical cell in series or parallel, and an electrical bridge is flexible and extends across the bridge portion of the first substrate layer. A second substrate layer is connected to the first substrate layer such that both of the first and second electrochemical cells are separately sealed. The flexible battery is configured to be folded over itself along the bridge portion such that the first and second electrochemical cells are arranged in a covering relationship. Optionally, an open gap area is disposed over the bridge portion of the first substrate to facilitate folding the flexible battery over itself along a line extending through the bridge portion.
摘要翻译： 柔性电池包括具有第一单元部分的第一基底层，第二单元部分和连接第一和第二单元部分的桥接部分。 电桥将第一电化学电池串联或并联电耦合到第二电化学电池，并且电桥是柔性的并且延伸穿过第一衬底层的桥接部分。 第二衬底层连接到第一衬底层，使得第一和第二电化学电池单独地被密封。 柔性电池构造成沿着桥接部分自身折叠，使得第一和第二电化学电池被布置成覆盖关系。 可选地，开放间隙区域设置在第一基板的桥接部分上方，以便沿着延伸穿过桥接部分的线将柔性电池折叠在其自身上。
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公开(公告)号：US11819313B2
公开(公告)日：2023-11-21
申请号：US17064708
申请日：2020-10-07
发明人： John Gannon , Matt Ream , Frank Feddrix , Ruth Phillips , Adam Perer , Sashi Kolli
CPC分类号： A61B5/01 , A61B5/0008 , A61B5/7275 , A61B5/746 , G06N3/08
摘要： Continuous temperature monitors can be used to collect frequent temperature data over large periods of time. A machine learning system trained with collected temperature data can be used to predict future temperature data for patients. Such predictions can be clinically beneficial for disease states in which fever can be fatal, particularly for those fevers having fast onset. For example, patients undergoing chimeric antigen receptor T-cell (CAR-T) therapy may suffer fevers caused by cytokine release syndrome (CRS). Accordingly, a continuous temperature monitor is used to collect temperature data from CAR-T patients with high risk of CRS (or like patients with high fever risk), and the collected temperature data processed by a machine learning system to predict the patient's future temperature profiles. Results of analysis of the predicted temperature profiles may then be provided to the patient and/or clinician.
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公开(公告)号：US20160183794A1
公开(公告)日：2016-06-30
申请号：US14587626
申请日：2014-12-31
发明人： John Gannon , Matt Ream , Gary R. Tucholski
CPC分类号： A61B5/0008 , A61B5/0024 , A61B5/01 , A61B5/6833 , A61B5/6898 , A61B5/743 , A61B2562/166
摘要： An actively-powered temperature data logger patch with wireless data communication includes a sealed, flexible battery comprising a printed electrochemical cell with an anode and a cathode, and a flexible circuit including a microprocessor, a temperature sensor configured to sense a temperature of a target subject, a wireless communication transmitter and an antenna. In one example, the temperature sensor is located at a first end of the patch, and the antenna is located at an opposite, second end of the patch. The patch is configured to conform to a curved surface of the target subject and includes an adhesive configured to be removably applied to skin of the patient. An external computing device is capable of receiving communication from the wireless communication transmitter of the patch via an electromagnetic field.
摘要翻译： 具有无线数据通信的主动供电的温度数据记录器补丁包括密封的柔性电池，其包括具有阳极和阴极的印刷电化学电池，以及包括微处理器的柔性电路，温度传感器，被配置为感测目标物体的温度 ，无线通信发射机和天线。 在一个示例中，温度传感器位于贴片的第一端，并且天线位于贴片的相对的第二端。 贴片被构造成符合目标对象的曲面，并且包括构造成可移除地施加到患者皮肤的粘合剂。 外部计算设备能够经由电磁场从补丁的无线通信发射机接收通信。
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公开(公告)号：US20190046033A1
公开(公告)日：2019-02-14
申请号：US15989674
申请日：2018-05-25
发明人： John Gannon , Matt Ream , James M. Petras
摘要： An actively-powered temperature data logger patch with wireless data communication includes a first substrate layer, a second substrate layer, a non-adhesive release layer, and an electronics inlay disposed between the first and second substrate layers. The electronics inlay includes a sealed, flexible battery, and a flexible circuit having a temperature sensor. An outer face of the non-adhesive release layer is has release properties. A replaceable adhesive includes a carrier substrate, a structural adhesive coated on a first face and attached to the outer face of the non-adhesive release layer, and a skin-contact approved adhesive coated on a second opposite face. In another example, an auxiliary sleeve having an exterior surface with an adhesive configured to be removably applied to a subject, may partially enclose the temperature data logger patch in an internal compartment.
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公开(公告)号：US20180028073A1
公开(公告)日：2018-02-01
申请号：US15726908
申请日：2017-10-06
CPC分类号： A61B5/01 , A61B5/0008 , A61B5/002 , A61B5/6833 , A61B2560/0204 , A61B2562/0271 , G01K1/022 , G01K1/024 , G01K13/002
摘要： An actively-powered medical system for monitoring a body temperature of a patient includes a temperature data logger patch with wireless data communication includes a sealed, flexible battery comprising a printed electrochemical cell with an anode and a cathode, and a flexible circuit including a microprocessor, a temperature sensor configured to sense a temperature of a target subject, a wireless communication transceiver and an antenna. In one example, the patch is configured to conform to a curved surface of the target subject. In another example, the patch is used in an actively-powered medical system for monitoring a body temperature of a patient, and includes an adhesive configured to be removably applied to skin of the patient. An external computing device is capable of communication with the wireless communication transceiver of the patch via an electromagnetic field.
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公开(公告)号：US09027242B2
公开(公告)日：2015-05-12
申请号：US13625366
申请日：2012-09-24
发明人： Gary R. Tucholski
CPC分类号： H01M2/30 , H01M4/42 , H01M6/005 , H01M6/12 , H05K1/16 , H05K2201/10037 , Y10T29/49108 , Y10T29/4911 , Y10T29/49128 , Y10T29/4913 , Y10T29/49169 , Y10T29/49226
摘要： A method of manufacturing an electrical device comprises the steps of providing a substrate, providing an electrical component on the substrate, providing a first electrical contact on the substrate that is electrically connected to the electrical component, and providing an electrochemical cell on or integrating the substrate for providing electrical energy to said electrical component. The electrochemical cell comprises at least one electrochemical layer comprising a cured or dried ink and a first electrode contact electrically connected to said at least one electrochemical layer. The method further includes the step of securing the electrochemical cell to the substrate through an electrically conductive connection that provides both a structural connection and an electrical connection between the first electrical contact and the first electrode contact.
摘要翻译： 制造电子器件的方法包括以下步骤：提供衬底，在衬底上提供电子部件，在衬底上提供电连接到电气部件上的第一电接触，以及在衬底上提供电化学电池 用于向所述电气部件提供电能。 电化学电池包括至少一个包含固化或干燥的油墨的电化学层和与所述至少一个电化学层电连接的第一电极接触。 该方法还包括通过提供第一电触点和第一电触点之间的结构连接和电连接的导电连接将电化学电池固定到基板的步骤。
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公开(公告)号：US08765284B2
公开(公告)日：2014-07-01
申请号：US13899291
申请日：2013-05-21
发明人： Gary R. Tucholski
CPC分类号： H01M6/40 , H01M2/0222 , H01M2/08 , H01M2/204 , H01M2/361 , H01M6/42 , H01M10/0427 , H01M10/285 , H01M10/365 , H01M12/085 , Y02E60/128
摘要： A flexible battery includes a first substrate layer with a first cell portion, a second cell portion, and a bridge portion connecting the first and second cell portions. An electrical bridge electrically couples a first electrochemical cell to a second electrochemical cell in series or parallel, and an electrical bridge is flexible and extends across the bridge portion of the first substrate layer. A second substrate layer is connected to the first substrate layer such that both of the first and second electrochemical cells are separately sealed. The flexible battery is configured to be folded over itself along the bridge portion such that the first and second electrochemical cells are arranged in a covering relationship. Optionally, an open gap area is disposed over the bridge portion of the first substrate to facilitate folding the flexible battery over itself along a line extending through the bridge portion.
摘要翻译： 柔性电池包括具有第一单元部分的第一基底层，第二单元部分和连接第一和第二单元部分的桥接部分。 电桥将第一电化学电池串联或并联电耦合到第二电化学电池，并且电桥是柔性的并且延伸穿过第一衬底层的桥接部分。 第二衬底层连接到第一衬底层，使得第一和第二电化学电池单独地被密封。 柔性电池构造成沿着桥接部分自身折叠，使得第一和第二电化学电池被布置成覆盖关系。 可选地，开放间隙区域设置在第一基板的桥接部分上方，以便沿着延伸穿过桥接部分的线将柔性电池折叠在其自身上。
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公开(公告)号：US20140121557A1
公开(公告)日：2014-05-01
申请号：US13926508
申请日：2013-06-25
IPC分类号： A61B5/01
CPC分类号： A61B5/01 , A61B5/0008 , A61B5/002 , A61B5/6833 , A61B2560/0204 , A61B2562/0271 , G01K1/022 , G01K1/024 , G01K13/002
摘要： An actively-powered temperature data logger patch with wireless data communication includes a sealed, flexible battery comprising a printed electrochemical cell with an anode and a cathode, and a flexible circuit including a microprocessor, a temperature sensor configured to sense a temperature of a target subject, a wireless communication transceiver and an antenna. In one example, the flexible battery and flexible circuit are arranged in a covering, stacked arrangement between first and second substrate layers, and the patch configured to conform to a curved surface of the target subject. In another example, the patch is used in an actively-powered medical system for monitoring a body temperature of a patient, and includes an adhesive configured to be removably applied to skin of the patient. An external computing device is capable of two way communication with the wireless communication transceiver of the patch via an electromagnetic field.
摘要翻译： 具有无线数据通信的主动供电的温度数据记录器补丁包括密封的柔性电池，其包括具有阳极和阴极的印刷电化学电池，以及包括微处理器的柔性电路，温度传感器，被配置为感测目标物体的温度 ，无线通信收发器和天线。 在一个示例中，柔性电池和柔性电路布置在第一和第二基底层之间的覆盖层叠布置中，并且所述贴片被配置成符合目标对象的曲面。 在另一示例中，所述贴片用于主动式医疗系统中，用于监测患者的体温，并且包括被配置为可移除地施加到患者皮肤的粘合剂。 外部计算设备能够通过电磁场与补丁的无线通信收发器进行双向通信。
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