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    COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS
    1.
    发明申请
    COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS 审中-公开
    组合物及其控制方法

    公开(公告)号：US20150305341A1

    公开(公告)日：2015-10-29

    申请号：US14793893

    申请日：2015-07-08

    Applicant: Karen E. Broglie ,  Kevin Kriss ,  Albert L. Lu ,  Mani Muthalagi ,  James Kevin Presnail

    Inventor： Karen E. Broglie ,  Kevin Kriss ,  Albert L. Lu ,  Mani Muthalagi ,  James Kevin Presnail

    IPC: A01N57/16 ,  A01N65/20 ,  A01N65/44 ,  C12N15/82 ,  C12N15/113

    CPC classification number: A01N57/16 ,  A01N63/00 ,  A01N65/20 ,  A01N65/44 ,  C12N15/113 ,  C12N15/8218 ,  C12N15/8286 ,  C12N2310/11 ,  C12N2310/531 ,  Y02A40/162

    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 1-236 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is D. virgifera virgifera, D. barberi, D. speciosa, or D. undecimpunctata howardi. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.

    Abstract translation: 提供了使用沉积元件的方法和组合物，当由有害生物摄取的诸如鞘翅目植物病虫害（Diaprotica plant pest）的害虫时，会降低害虫中靶序列的表达。 在具体实施方案中，靶序列的表达降低控制有害生物，因此方法和组合物能够限制对植物的损害。 本发明提供了SEQ ID NO：1-236中任一项所述的各种靶多核苷酸或其活性变体及其片段，其中目标害虫中一个或多个序列的表达降低控制害虫（即具有杀虫活性 活动）。 进一步提供的是沉积元件，当受害虫摄入时，降低靶多肽的水平，从而控制害虫。 在具体实施方案中，害虫是D. virgifera virgifera，D.barberi，D. speciosa或D. undecimpunctata howardi。 还提供了包含本发明的沉默元件或其活性变体或片段的植物，植物部分，细菌和其它宿主细胞。

    Viral promoter, truncations thereof, and methods of use
    2.
    发明授权
    Viral promoter, truncations thereof, and methods of use 有权
    病毒启动子，其截短物和使用方法

    公开(公告)号：US08895716B2

    公开(公告)日：2014-11-25

    申请号：US13332439

    申请日：2011-12-21

    Applicant: Scott Diehn ,  Albert L. Lu ,  Carl R. Simmons

    Inventor： Scott Diehn ,  Albert L. Lu ,  Carl R. Simmons

    IPC: C07H21/04 ,  C12N15/82 ,  C12N15/87 ,  C12N15/00 ,  C12N5/10 ,  A01H5/00

    CPC classification number: C12N15/8225 ,  C12N2730/00043

    Abstract: The present disclosure provides compositions and methods for regulating expression of heterologous nucleotide sequences in a plant. Compositions include a novel nucleotide sequence for a promoter. A method for expressing a heterologous nucleotide sequence in a plant using the promoter sequence disclosed herein is provided. The method comprises stably incorporating into the genome of a plant cell a nucleotide sequence operably linked to the promoter of the present invention and regenerating a stably transformed plant that expresses the nucleotide sequence.

    Abstract translation: 本公开提供了用于调节植物中异源核苷酸序列表达的组合物和方法。 组合物包括用于启动子的新型核苷酸序列。 提供了使用本文公开的启动子序列在植物中表达异源核苷酸序列的方法。 该方法包括将与本发明的启动子可操作地连接的核苷酸序列稳定地并入植物细胞的基因组中，并再生表达核苷酸序列的稳定转化的植物。

    Viral promoter, truncations thereof, and methods of use
    4.
    发明授权
    Viral promoter, truncations thereof, and methods of use 有权

    公开(公告)号：US08344206B2

    公开(公告)日：2013-01-01

    申请号：US12775669

    申请日：2010-05-07

    Applicant: Scott Diehn ,  Albert L. Lu ,  Carl R. Simmons

    Inventor： Scott Diehn ,  Albert L. Lu ,  Carl R. Simmons

    IPC: C12N15/82 ,  C12N15/113 ,  C12N5/10

    CPC classification number: C12N15/8216

    Abstract: The present disclosure provides compositions and methods for regulating expression of heterologous nucleotide sequences in a plant. Compositions include a novel nucleotide sequence for a promoter. A method for expressing a heterologous nucleotide sequence in a plant using the promoter sequence disclosed herein is provided. The method comprises stably incorporating into the genome of a plant cell a nucleotide sequence operably linked to the promoter of the present invention and regenerating a stably transformed plant that expresses the nucleotide sequence.

    VIRAL PROMOTER, TRUNCATIONS THEREOF, AND METHODS OF USE
    6.
    发明申请
    VIRAL PROMOTER, TRUNCATIONS THEREOF, AND METHODS OF USE 有权
    司法促进者，其职权及其使用方法

    公开(公告)号：US20120167249A1

    公开(公告)日：2012-06-28

    申请号：US13329511

    申请日：2011-12-19

    Applicant: Scott Diehn ,  Albert L. Lu ,  Carl R. Simmons

    Inventor： Scott Diehn ,  Albert L. Lu ,  Carl R. Simmons

    IPC: A01H1/00 ,  C12N15/82 ,  A01H5/00 ,  A01H5/10 ,  C12N15/63 ,  C12N5/04

    CPC classification number: C12N15/8226 ,  C12N15/8216 ,  C12N15/8227 ,  C12N15/8286 ,  Y02A40/162

    Abstract: The present disclosure provides compositions and methods for regulating expression of heterologous nucleotide sequences in a plant. Compositions include a novel nucleotide sequence for a promoter. A method for expressing a heterologous nucleotide sequence in a plant using the promoter sequence disclosed herein is provided. The method comprises stably incorporating into the genome of a plant cell a nucleotide sequence operably linked to the promoter of the present invention and regenerating a stably transformed plant that expresses the nucleotide sequence.

    Abstract translation: 本公开提供了用于调节植物中异源核苷酸序列表达的组合物和方法。 组合物包括用于启动子的新型核苷酸序列。 提供了使用本文公开的启动子序列在植物中表达异源核苷酸序列的方法。 该方法包括将与本发明的启动子可操作地连接的核苷酸序列稳定地并入植物细胞的基因组中，并再生表达核苷酸序列的稳定转化的植物。

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