公开(公告)号：US09649424B2

公开(公告)日：2017-05-16

申请号：US13381433

申请日：2010-06-28

申请人： Nobuhiko Sato ,  Shinya Yoshida ,  Akira Kobayashi ,  Masaru Nakatani

发明人： Nobuhiko Sato ,  Shinya Yoshida ,  Akira Kobayashi ,  Masaru Nakatani

IPC分类号： C12N15/10 ,  A61M1/36 ,  A61M1/02 ,  B01D39/16 ,  D04H1/4382

CPC分类号： A61M1/3679 ,  A61M1/02 ,  A61M1/0209 ,  A61M1/0218 ,  A61M2202/0427 ,  A61M2202/0429 ,  A61M2202/0439 ,  B01D39/1623 ,  B01D2239/1208 ,  B01D2239/1233 ,  C12N15/1017 ,  D04H1/4382

摘要： The present invention relates to a separation system and a separation material for easily and rapidly separating a red blood cell-rich fraction, a white blood cell-rich fraction, and/or a platelet-rich fraction from a biological fluid containing these blood cell components without the necessity of performing centrifugation. The separation of a red blood cell-rich fraction, a white blood cell-rich fraction, and/or a platelet-rich fraction from a biological fluid can be accomplished by capturing white blood cells and platelets on a blood cell separation material by contacting the biological fluid with the blood cell separation material, thereby providing a red blood cell-rich fraction; and recovering a white blood cell-rich fraction by separating white blood cells captured from the resulting blood cell separation material using a separation solution.

公开(公告)号：US09273275B2

公开(公告)日：2016-03-01

申请号：US13807546

申请日：2011-06-30

申请人： Akira Kobayashi ,  Masaki Ichimura ,  Masaru Nakatani

发明人： Akira Kobayashi ,  Masaki Ichimura ,  Masaru Nakatani

IPC分类号： C12M3/00 ,  C12M1/00 ,  C12M3/06

CPC分类号： C12M3/06 ,  C12M23/28 ,  C12M23/44 ,  C12M29/00 ,  C12M29/16 ,  C12M33/14 ,  C12M45/00 ,  C12M47/02 ,  C12M47/04

摘要： It is an object to achieve a closed system that has a simple structure without resorting to large scale equipment and that sequentially carries out all of the step of separating useful cells, the step of culturing the useful cells separated in the separation step, and the step of washing and concentrating the cells cultured in the culturing step and to enable the preparation of useful cells having high safety and quality, while improving operability. A disposable set for cell culture includes a cell culture container (CC) having a liquid inlet (Lin) and a liquid outlet (Lout), a cell separation kit (A) that is for separating cells used for cell culture and is connected to the liquid inlet (Lin), and a cell collection kit (B) that is for washing and concentrating cultured cells in the cell culture container (CC) and is connected to the liquid outlet (Lout), and a cell culture device uses the disposable set for cell culture and includes flow path on-off valves and pumps provided at appropriate positions of pipelines of the disposable set and a controller controlling them.

摘要翻译： 本发明的目的是实现具有简单结构的封闭系统，而不需要大型设备，并且顺序地执行分离有用细胞的所有步骤，培养在分离步骤中分离的有用细胞的步骤，以及步骤 洗涤和浓缩培养步骤中培养的细胞，并且能够制备具有高安全性和质量的有用细胞，同时提高可操作性。 用于细胞培养的一次性装置包括具有液体入口（Lin）和液体出口（Lout）的细胞培养容器（CC），用于分离用于细胞培养的细胞的细胞分离试剂盒（A），并连接到 液体入口（Lin）和用于在细胞培养容器（CC）中洗涤和浓缩培养细胞并连接到液体出口（Lout）的细胞收集试剂盒（B），细胞培养装置使用一次性组 用于细胞培养，并且包括在一次性组的管道的适当位置处设置的流路开关阀和泵，以及控制它们的控制器。

公开(公告)号：US09057052B2

公开(公告)日：2015-06-16

申请号：US12091029

申请日：2006-10-20

申请人： Akira Kobayashi ,  Kazuaki Yamamoto ,  Shinya Yoshida ,  Hideo Niwa ,  Naohiro Imai ,  Hirokazu Kurata ,  Yoshiaki Miyamoto

发明人： Akira Kobayashi ,  Kazuaki Yamamoto ,  Shinya Yoshida ,  Hideo Niwa ,  Naohiro Imai ,  Hirokazu Kurata ,  Yoshiaki Miyamoto

IPC分类号： C12M1/12 ,  C12M1/00 ,  C12M1/36 ,  C12N5/00 ,  C12N5/074 ,  B01D39/16 ,  C12M1/26

CPC分类号： C12N5/0607 ,  B01D39/1623 ,  B01D39/1692 ,  B01D2239/0414 ,  C12M33/14 ,  C12M47/02

摘要： The present invention has its object to provide a material for separating stem cell and a filter for separating stem cell, each is capable of selectively separating and recovering, in a simple and easy manner, stem cells from body fluids or biological tissue-derived treated fluids, a method for separating and recovering stem cells, and stem cells obtained by such method. The present invention is a material for separating stem cell which has a density K of 1.0×104≦K≦1.0×106 and a fiber diameter of 3 to 40 μm; a filter for separating stem cell which comprises the material for separating stem cell as packed in a container having a fluid inlet port and a fluid outlet port; a method of separating and recovering stem cells which comprises using the material for separating stem cell or the filter for separating stem cell; and a method of producing a multipotent cell fraction.

摘要翻译： 本发明的目的是提供用于分离干细胞的材料和用于分离干细胞的过滤器，每种能够以简单和容易的方式从体液或生物组织衍生的处理液中分离和回收干细胞 ，分离和回收干细胞的方法和通过这种方法获得的干细胞。 本发明是一种分离干细胞的材料，其密度K为1.0×104＆nlE; K＆NlE; 1.0×106，纤维直径为3〜40μm; 用于分离干细胞的过滤器，其包括用于分离干细胞的材料，所述干细胞包装在具有流体入口和流体出口的容器中; 分离和回收干细胞的方法，其包括使用用于分离干细胞的材料或用于分离干细胞的过滤器; 以及多能细胞部分的制造方法。

公开(公告)号：US08560135B2

公开(公告)日：2013-10-15

申请号：US13028388

申请日：2011-02-16

申请人： Yasushi Tomita ,  Masahiro Watanabe ,  Takafumi Ebara ,  Yuichi Otake ,  Akira Kobayashi ,  Hideyuki Kawamura

发明人： Yasushi Tomita ,  Masahiro Watanabe ,  Takafumi Ebara ,  Yuichi Otake ,  Akira Kobayashi ,  Hideyuki Kawamura

IPC分类号： G05D3/12

CPC分类号： H02J3/32 ,  H02J7/35 ,  H02J15/00 ,  Y02E10/566 ,  Y02E70/30 ,  Y02P90/50

摘要： An energy management system includes an equipment data management unit which manages charging/discharging loss of a battery and heat radiation loss of an electric water heater, and causes a control unit to perform control to give priority based on the comparison to the energy storage facility more reducing loss and store energy. The energy management system includes a system operation calculation unit which predicts voltage distribution of the next day of a distribution system or demand-and-supply balance amount of the entire system by state monitoring data of a power system, calculates a demand amount increasing target value necessary for avoiding a photovoltaic power generation amount suppression on a consumer end by the voltage distribution of the next day of the distribution system or the demand-and-supply balance amount, and controls the energy storage facilities so as to satisfy the demand amount increasing target value on the consumer end.

摘要翻译： 能量管理系统包括管理电池的充放电损失和电热水器的散热损失的设备数据管理单元，并且使得控制单元基于与能量存储设备的比较来执行优先级的控制 减少损耗和储存能量。 能量管理系统包括：系统运算计算单元，其通过电力系统的状态监视数据来预测分配系统的下一天的电压分配或整个系统的供电平衡量，计算需求量增加目标值 必须通过分配系统的第二天的电压分配或需求 - 供给平衡量来避免消费者端的光伏发电量抑制，并且控制能量存储设施以满足需求量增加目标 价值在消费者端。

公开(公告)号：US07946600B2

公开(公告)日：2011-05-24

申请号：US12283950

申请日：2008-09-17

申请人： Akira Kobayashi

发明人： Akira Kobayashi

IPC分类号： B60G11/28 ,  B60G11/20 ,  B60G11/32

CPC分类号： B60G21/051 ,  B60G13/16 ,  B60G2202/1362 ,  B60G2202/25 ,  B60G2204/122

摘要： In a torsion beam wheel suspension system, a stabilizer bush made of resilient material is received in a hollow interior of a torsion beam that connect intermediate points of a pair of trailing arms, and retains an intermediate part of the stabilizer to the torsion beam. A bracket including a pair of vertical walls opposing lateral sides of the stabilizer bush is attached to a part of the torsion beam to prevent the lateral shifting of the stabilizer bush without any part of the bracket or stabilizer bush restraining the torsional deformation of the stabilizer or torsion beam. The vertical walls may be spaced apart from the stabilizer bush. The structure is not costly and does not cause any complication or difficulty in the assembly work of the rear wheel suspension system. The bracket may have dual purposes of retaining the stabilizer bush and supporting a dynamic damper.

摘要翻译： 在扭力梁车轮悬挂系统中，由弹性材料制成的稳定器衬套被容纳在扭转梁的中空内部，该扭转梁连接一对牵引臂的中间点，并将稳定器的中间部分保持在扭转梁上。 包括一对相对于稳定器衬套横向侧面的垂直壁的托架被安装在扭转梁的一部分上，以防止稳定器衬套的横向移动，而没有任何支架或稳定器衬套的任何部分限制稳定器的扭转变形或 扭力梁。 垂直壁可以与稳定器衬套间隔开。 该结构不是昂贵的，并且不会导致后轮悬挂系统的组装工作的任何复杂性或困难。 支架可以具有保持稳定器衬套和支撑动态阻尼器的双重目的。

公开(公告)号：US07923130B2

公开(公告)日：2011-04-12

申请号：US12599756

申请日：2008-05-23

申请人： Akihiko Shibata ,  Haruyo Fukui ,  Shinya Imamura ,  Akira Kobayashi

发明人： Akihiko Shibata ,  Haruyo Fukui ,  Shinya Imamura ,  Akira Kobayashi

IPC分类号： B32B9/00 ,  B23B27/14

CPC分类号： C23C14/0641 ,  C23C14/0664 ,  C23C14/32 ,  C23C28/042 ,  C23C28/044 ,  C23C28/42 ,  C23C30/005 ,  Y10T428/24975 ,  Y10T428/26 ,  Y10T428/265 ,  Y10T428/30 ,  Y10T428/31678

摘要： A surface-coated cutting tool according to the present invention including a substrate and a coating film formed on the substrate is characterized in that the coating film includes a composite super multi-layer film obtained by alternately stacking one or more first super multi-layer film and one or more second super multi-layer film, the first super multi-layer film above is formed by alternately stacking one or more A1 layer and one or more B layer, the second super multi-layer film above is formed by alternately stacking one or more A2 layer and one or more C layer, each of the A1 layer above and the A2 layer above is composed of any of TiN, TiCN, TiAlN, and TiAlCN, the B layer above is composed of TiSiN or TiSiCN, and the C layer above is composed of AlCrN or AlCrCN.

摘要翻译： 根据本发明的表面涂层切削工具，其特征在于，包括基板和形成在所述基板上的涂膜，其特征在于，所述涂膜包括复合超多层膜，其通过交替地层叠一个以上的第一超多层膜 和一个或多个第二超多层膜，上述第一超多层膜通过交替堆叠一个或多个Al层和一个或多个B层形成，上述第二超多层膜通过交替堆叠一个 或更多的A2层和一层或多层C层，上述A1层和A2层均由TiN，TiCN，TiAlN和TiAlCN中的任一种构成，上述B层由TiSiN或TiSiCN组成，C层 以上层由AlCrN或AlCrCN组成。

公开(公告)号：US20110078283A1

公开(公告)日：2011-03-31

申请号：US12674219

申请日：2008-08-12

申请人： Junichi Gokurakuji ,  Akira Kobayashi ,  Katsuhiro Ochiai ,  Shigeki Mukaiyama ,  Motonobu Kimura ,  Kaname Naito ,  Shuhei Miura ,  Kaori Sugiyama

发明人： Junichi Gokurakuji ,  Akira Kobayashi ,  Katsuhiro Ochiai ,  Shigeki Mukaiyama ,  Motonobu Kimura ,  Kaname Naito ,  Shuhei Miura ,  Kaori Sugiyama

IPC分类号： G06F15/16

CPC分类号： G06Q10/107 ,  G06Q10/06 ,  G06Q50/32 ,  H04L63/02 ,  H04L63/168 ,  H04W76/10

摘要： A service providing system is connected to a user terminal via a network, acquires a request message described with an upper layer protocol exceeding three layers for requesting desired data and transmitted by the user terminal, and analyzes the content of a body portion of the message. In the case where unwanted information or unusual information is contained in request content, the unwanted information or the unusual information is eliminated by subjecting the request message to a predefined process.

摘要翻译： 服务提供系统经由网络连接到用户终端，获取用超过三层的上层协议描述的请求消息，用于请求所需数据并由用户终端发送，并分析消息的正文部分的内容。 在请求内容中包含不需要的信息或异常信息的情况下，通过对请求消息进行预定义的处理来消除不需要的信息或异常信息。

公开(公告)号：US20110002552A1

公开(公告)日：2011-01-06

申请号：US12745011

申请日：2008-11-26

申请人： Yutaka Yamamoto ,  Masaaki Nagahara ,  Akira Kobayashi

发明人： Yutaka Yamamoto ,  Masaaki Nagahara ,  Akira Kobayashi

IPC分类号： G06K9/36

CPC分类号： H04N19/117 ,  H04N19/14 ,  H04N19/176 ,  H04N19/436 ,  H04N19/86

摘要： An FFT analysis is performed to the image data of one frame which has been decoded, and a cutoff frequency on the assumption that the original signal has first-order attenuation characteristics is obtained each in the horizontal direction and in the vertical direction. A sampled-data H∞ filter (digital filter) which has been previously designed in such a manner as to have different parameters corresponding to different cutoff frequencies is selected. By using this filter, a filtering process is performed to the image data which has been decoded both in the horizontal direction and in the vertical direction. Since the variety of the analog frequency characteristics of the original image is taken into account for every frame of image, the information that seems to be a noise yet actually exists in the original image is less likely to be removed, and a mosquito noise and block noise associated with a coding/decoding process can be efficiently removed.

摘要翻译： 对已经解码的一帧的图像数据执行FFT分析，并且假定在水平方向和垂直方向上都获得了原始信号具有一阶衰减特性的截止频率。 选择先前以具有对应于不同截止频率的不同参数设计的采样数据H∞滤波器（数字滤波器）。 通过使用该滤波器，对在水平方向和垂直方向上解码的图像数据进行滤波处理。 由于对于每一帧图像都考虑了原始图像的模拟频率特性的多样性，原始图像中实际上仍然存在噪声的信息不太可能被去除，并且蚊子噪声和阻塞 可以有效地去除与编码/解码处理相关联的噪声。

公开(公告)号：US20100235702A1

公开(公告)日：2010-09-16

申请号：US12716340

申请日：2010-03-03

申请人： JIRO TANIMOTO ,  Akira Kobayashi

发明人： JIRO TANIMOTO ,  Akira Kobayashi

IPC分类号： H04L1/18 ,  G06F11/14

CPC分类号： H04L1/1887 ,  H04L2001/0093

摘要： Intended is to avoid retransmission requests from congesting and data retransmission from being disabled.The receiver 200, when detecting an error whose error correction by an error correcting code is impossible, transmits a request for retransmitting the block to the transmitter 100 through the unicast network 400, and the transmitter 100 receives the retransmission request and selects either the multicast network 300 or the unicast network 400 according to the number of retransmission requests transmitted from the receiver 200 to control simultaneous retransmission of the block.

摘要翻译： 旨在避免来自拥塞和数据重传的重传请求被禁用。 接收机200通过单播网络400发送通过纠错码进行纠错的错误时，通过单播网络400向发送机100发送重发请求，发送机100接收重发请求，并选择组播网络 300或单播网络400，根据从接收机200发送的重发请求的数量，以控制块的同时重传。

公开(公告)号：US20100215951A1

公开(公告)日：2010-08-26

申请号：US12599756

申请日：2008-05-23

申请人： Akihiko Shibata ,  Haruyo Fukui ,  Shinya Imamura ,  Akira Kobayashi

发明人： Akihiko Shibata ,  Haruyo Fukui ,  Shinya Imamura ,  Akira Kobayashi

IPC分类号： B32B9/00 ,  B32B15/04

CPC分类号： C23C14/0641 ,  C23C14/0664 ,  C23C14/32 ,  C23C28/042 ,  C23C28/044 ,  C23C28/42 ,  C23C30/005 ,  Y10T428/24975 ,  Y10T428/26 ,  Y10T428/265 ,  Y10T428/30 ,  Y10T428/31678

摘要： A surface-coated cutting tool according to the present invention including a substrate and a coating film formed on the substrate is characterized in that the coating film includes a composite super multi-layer film obtained by alternately stacking one or more first super multi-layer film and one or more second super multi-layer film, the first super multi-layer film above is formed by alternately stacking one or more A1 layer and one or more B layer, the second super multi-layer film above is formed by alternately stacking one or more A2 layer and one or more C layer, each of the A1 layer above and the A2 layer above is composed of any of TiN, TiCN, TiAlN, and TiAlCN, the B layer above is composed of TiSiN or TiSiCN, and the C layer above is composed of AlCrN or AlCrCN.

摘要翻译： 根据本发明的表面涂层切削工具，其特征在于，包括基板和形成在所述基板上的涂膜，其特征在于，所述涂膜包括复合超多层膜，其通过交替地层叠一个以上的第一超多层膜 和一个或多个第二超多层膜，上述第一超多层膜通过交替堆叠一个或多个Al层和一个或多个B层形成，上述第二超多层膜通过交替堆叠一个 或更多的A2层和一层或多层C层，上述A1层和A2层均由TiN，TiCN，TiAlN和TiAlCN中的任一种构成，上述B层由TiSiN或TiSiCN组成，C层 以上层由AlCrN或AlCrCN组成。