公开(公告)号：US10016592B2

公开(公告)日：2018-07-10

申请号：US14517611

申请日：2014-10-17

Applicant: Asthmatx, Inc.

Inventor： Michael Biggs ,  Roger A. Stern ,  Christopher J. Danek

IPC: A61B18/14 ,  A61N1/06 ,  A61N1/40 ,  A61B18/00

CPC classification number: A61N1/06 ,  A61B18/14 ,  A61B2018/00541 ,  A61N1/40

Abstract: The present disclosure may include a system for delivering energy to an airway wall of a lung comprising an energy delivering apparatus and a PID controller having one or more variable gain factors. The energy delivering apparatus may include a flexible elongated member and a distal expandable basket having at least one electrode for transferring energy to the airway wall and at least one temperature sensor for measuring temperature.

公开(公告)号：US09358024B2

公开(公告)日：2016-06-07

申请号：US13894164

申请日：2013-05-14

Applicant: Asthmatx, Inc.

Inventor： Christopher James Danek ,  Michael Biggs ,  Bryan E. Loomas ,  Michael D. Laufer ,  Gary Kaplan ,  Kelly M. Shriner

IPC: A61B17/24 ,  A61B18/18 ,  A61B18/00 ,  A61B17/22 ,  A61B18/08 ,  A61B18/14 ,  A61B17/00 ,  A61B18/04 ,  A61B19/00 ,  A61M25/00 ,  A61M29/00 ,  A61N5/06 ,  A61N1/36

CPC classification number: A61B17/24 ,  A61B17/22004 ,  A61B18/00 ,  A61B18/08 ,  A61B18/14 ,  A61B18/1492 ,  A61B18/18 ,  A61B2017/00115 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/22062 ,  A61B2017/242 ,  A61B2018/00083 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00541 ,  A61B2018/00654 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00803 ,  A61B2018/044 ,  A61B2018/046 ,  A61B2018/1807 ,  A61B2090/3614 ,  A61M25/0043 ,  A61M29/00 ,  A61M2025/0096 ,  A61M2210/1039 ,  A61N1/3601 ,  A61N5/0601

Abstract: This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.

公开(公告)号：US20160038230A1

公开(公告)日：2016-02-11

申请号：US14920006

申请日：2015-10-22

Applicant: Asthmatx, Inc.

Inventor： Christopher J. DANEK ,  William WIZEMAN ,  Timothy R. DALBEC ,  Glendon E. FRENCH ,  Michael D. LAUFER

IPC: A61B18/14 ,  A61B1/267 ,  A61B1/00 ,  A61B1/04 ,  A61B8/08 ,  A61B6/03

CPC classification number: A61B18/1492 ,  A61B1/00045 ,  A61B1/04 ,  A61B1/2676 ,  A61B6/032 ,  A61B6/037 ,  A61B8/08 ,  A61B18/1233 ,  A61B34/20 ,  A61B34/25 ,  A61B90/361 ,  A61B2017/00119 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00541 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00898 ,  A61B2018/00904 ,  A61B2018/1475 ,  A61B2034/104 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2090/309 ,  A61B2090/365 ,  A61B2090/367 ,  A61B2090/374 ,  A61B2576/02 ,  A61N1/06 ,  A61N1/3601 ,  A61N1/378 ,  A61N1/403

Abstract: Methods for treating a network of organs including generating a map of at least a portion of the network of organs using a rendering system; selecting at least one treatment location within the luminal passageway of the network of organs; and applying an energy therapy to the treatment location to treat the smooth muscle tissue, where the energy therapy applied to the respective treatment location is defined by a plurality of parameters that are associated with a map. Such a system allows for historical or ideal treatment parameters to be identified, visually or otherwise to actual treatment locations. Also, control systems and methods for delivery of energy that may include control algorithms that prevent energy delivery if a fault is detected and may provide energy delivery to produce a substantially constant temperature at a delivery site. In some embodiments, the control systems and methods may be used to control the delivery of energy, such as radiofrequency energy, to body tissue, such as lung tissue.

Abstract translation: 用于治疗器官网络的方法，包括使用再现系统生成器官网络的至少一部分的地图; 在器官网络的管腔通道内选择至少一个治疗位置; 以及将能量疗法应用于治疗位置以治疗平滑肌组织，其中施加到相应治疗位置的能量疗法由与地图相关联的多个参数定义。 这样的系统允许将历史或理想的治疗参数在视觉上或其他方面被识别到实际的治疗位置。 此外，用于递送能量的控制系统和方法可以包括如果检测到故障时防止能量传递的控制算法，并且可以提供能量输送以在输送部位产生基本上恒定的温度。 在一些实施例中，控制系统和方法可用于控制诸如射频能量的能量传递到诸如肺组织的身体组织。

公开(公告)号：US20160008066A1

公开(公告)日：2016-01-14

申请号：US14861647

申请日：2015-09-22

Applicant: Asthmatx, Inc.

Inventor： Gary S. KAPLAN ,  Christopher J. DANEK ,  William J. WIZEMAN ,  Timothy R. DALBEC ,  Noah D. WEBSTER ,  Huy D. PHAN

IPC: A61B18/14 ,  A61B18/18

CPC classification number: A61B18/1492 ,  A61B18/18 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00541 ,  A61B2018/00797 ,  A61B2018/1437 ,  A61F7/123 ,  A61N1/05

Abstract: This relates to methods and devices for achieving contact between the wall of a cavity or passageway and a medical device when used in tortuous anatomy.

公开(公告)号：US20140018789A1

公开(公告)日：2014-01-16

申请号：US14024340

申请日：2013-09-11

Applicant: Asthmatx, Inc.

Inventor： Gary S. KAPLAN ,  Christopher J. DANEK ,  William J. WIZEMAN ,  Timothy R. DALBEC ,  Noah WEBSTER ,  Huy PHAN

IPC: A61B18/18

CPC classification number: A61B18/1492 ,  A61B18/18 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00541 ,  A61B2018/00797 ,  A61B2018/1437 ,  A61F7/123 ,  A61N1/05

Abstract: A method for treating a subject includes positioning an intraluminal device at a treatment location in an airway of the subject, and delivering energy from an electrode of the intraluminal device to nerve tissue extending along the airway so as to permanently damage the nerve tissue while cooling airway tissue disposed radially between the electrode and the nerve tissue.

Abstract translation: 用于治疗受试者的方法包括将管腔内装置定位在受试者的气道中的治疗位置处，并且将能量从管腔内装置的电极传送到沿着气道延伸的神经组织，以便在冷却气道时永久性地损伤神经组织 组织放置在电极和神经组织之间。

公开(公告)号：US10278766B2

公开(公告)日：2019-05-07

申请号：US14171973

申请日：2014-02-04

Applicant: Asthmatx, Inc.

Inventor： Christopher J. Danek ,  Michael Biggs ,  Bryan E. Loomas ,  Michael D. Laufer ,  Gary S. Kaplan ,  Kelly M. Shriner ,  William J. Wizeman

IPC: A61B18/18 ,  A61B18/14 ,  A61B1/00 ,  A61B5/053 ,  A61B5/08 ,  A61B5/107 ,  A61B5/00 ,  A61B10/04 ,  A61B18/06 ,  A61N5/10 ,  A61B17/00 ,  A61B18/00 ,  A61B90/00

Abstract: This relates to treating airways in a lung to decrease asthmatic symptoms. The also includes steps of measuring a parameter of an airway at a plurality of locations in a lung, identifying at least one treatment site from at least one of the plurality of locations based on the parameter, and applying energy to the treatment site to reduce the ability of the site to narrow.

公开(公告)号：US10219858B2

公开(公告)日：2019-03-05

申请号：US14336678

申请日：2014-07-21

Applicant: Asthmatx, Inc.

Inventor： Christopher J. Danek ,  William Wizeman ,  Timothy R. Dalbec ,  Gary Kaplan

IPC: A61B18/14 ,  A61B18/12 ,  A61N1/06 ,  A61N1/40 ,  A61N1/36 ,  A61B34/20 ,  A61B17/00 ,  A61B18/00 ,  A61B90/30 ,  A61B34/00 ,  A61B90/00

Abstract: Control systems and methods for delivery of energy that may include control algorithms that prevent energy delivery if a fault is detected and may provide energy delivery to produce a substantially constant temperature at a delivery site. In some embodiments, the control systems and methods may be used to control the delivery of energy, such as radiofrequency energy, to body tissue, such as lung tissue.

公开(公告)号：US09931163B2

公开(公告)日：2018-04-03

申请号：US14695842

申请日：2015-04-24

Applicant: Asthmatx, Inc.

Inventor： Christopher J. Danek ,  Michael Biggs ,  Keith M. Burger ,  Bryan E. Loomas ,  Thomas M. Keast ,  Dave Haugaard

IPC: A61B18/14 ,  A61N1/06 ,  A61N5/00 ,  A61N1/40 ,  A61B18/08 ,  A61B17/00 ,  A61B18/00 ,  A61B18/04 ,  A61B90/00

CPC classification number: A61B18/1492 ,  A61B18/08 ,  A61B18/1477 ,  A61B2017/00084 ,  A61B2017/00123 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00541 ,  A61B2018/00791 ,  A61B2018/00982 ,  A61B2018/046 ,  A61B2018/1467 ,  A61B2018/1475 ,  A61B2018/1497 ,  A61B2090/3614 ,  A61N1/06 ,  A61N1/403 ,  A61N5/00

Abstract: An energy delivery device may include an elongate member having a proximal portion, a distal portion, and a lumen extending therebetween. The device may include a deployment member extending through the lumen toward a distal tip of the energy delivery device, and an expandable basket having a plurality of curved electrode legs. Each of the curved electrode legs may have a first end coupled to the distal portion of the elongate member and a second end coupled to the deployment member, and each of the plurality of curved electrode legs may have at least one energy insulated region and one energy active region. The device also may include at least one temperature sensing element coupled to said expandable basket.

公开(公告)号：US20150223879A1

公开(公告)日：2015-08-13

申请号：US14695842

申请日：2015-04-24

Applicant: Asthmatx, Inc.

Inventor： Christopher J. DANEK ,  Michael BIGGS ,  Keith M. BURGER ,  Bryan E. LOOMAS ,  Thomas M. KEAST ,  Dave HAUGAARD

IPC: A61B18/14 ,  A61N1/40

CPC classification number: A61B18/1492 ,  A61B18/08 ,  A61B18/1477 ,  A61B2017/00084 ,  A61B2017/00123 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00541 ,  A61B2018/00791 ,  A61B2018/00982 ,  A61B2018/046 ,  A61B2018/1467 ,  A61B2018/1475 ,  A61B2018/1497 ,  A61B2090/3614 ,  A61N1/06 ,  A61N1/403 ,  A61N5/00

Abstract: An energy delivery device may include an elongate member having a proximal portion, a distal portion, and a lumen extending therebetween. The device may include a deployment member extending through the lumen toward a distal tip of the energy delivery device, and an expandable basket having a plurality of curved electrode legs. Each of the curved electrode legs may have a first end coupled to the distal portion of the elongate member and a second end coupled to the deployment member, and each of the plurality of curved electrode legs may have at least one energy insulated region and one energy active region. The device also may include at least one temperature sensing element coupled to said expandable basket.

Abstract translation: 能量递送装置可以包括具有近端部分，远侧部分和在其间延伸的内腔的细长构件。 该装置可以包括展开构件，其延伸穿过内腔朝向能量递送装置的远端，以及具有多个弯曲电极腿的可扩张篮。 每个弯曲电极腿可以具有联接到细长构件的远侧部分的第一端和联接到展开构件的第二端，并且多个弯曲电极腿中的每一个可以具有至少一个能量绝缘区域和一个能量 活跃区域。 该装置还可以包括耦合到所述可膨胀篮的至少一个温度感测元件。

公开(公告)号：US09027564B2

公开(公告)日：2015-05-12

申请号：US13891959

申请日：2013-05-10

Applicant: Asthmatx, Inc.

Inventor： Christopher J. Danek ,  Bryan E. Loomas ,  Thomas M. Keast ,  Michael D. Laufer

IPC: A61B19/00 ,  A61F7/12 ,  A61N5/00 ,  A61B18/08 ,  A61B18/14 ,  A61M25/00 ,  A61M29/00 ,  A61M29/02 ,  A61N1/06 ,  A61N1/40 ,  A61B18/02 ,  A61B18/18 ,  A61B17/00 ,  A61B18/00

CPC classification number: A61B18/02 ,  A61B18/04 ,  A61B18/08 ,  A61B18/1492 ,  A61B18/18 ,  A61B2017/003 ,  A61B2018/00083 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00434 ,  A61B2018/00541 ,  A61B2018/00654 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00803 ,  A61B2018/0212 ,  A61B2090/3614 ,  A61F7/123 ,  A61F2007/0018 ,  A61F2007/0059 ,  A61F2007/126 ,  A61M25/0043 ,  A61M29/00 ,  A61M29/02 ,  A61M2025/0096 ,  A61M2210/1039 ,  A61N1/06 ,  A61N1/403 ,  A61N5/00

Abstract: An embodiment of the invention includes a method for decreasing resistance to airflow within a bronchial tree of a subject. The method may include the step of moving an intraluminal device along a lumen of an airway of a bronchial tree, where the intraluminal device includes an expandable member and an energy emitter. The method also may include damaging nerves along the airway using the intraluminal device without destroying an inner surface of an airway wall disposed radially between the intraluminal device and the nerves.

Abstract translation: 本发明的一个实施例包括一种降低对象支气管树内气流阻力的方法。 该方法可以包括沿着支气管树的气道的内腔移动管腔内装置的步骤，其中管腔内装置包括可扩张构件和能量发射器。 该方法还可以包括使用管腔内装置沿着气道的损伤性神经，而不会破坏设置在管腔内装置和神经之间径向的气道壁的内表面。