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公开(公告)号:US12070520B2
公开(公告)日:2024-08-27
申请号:US17073510
申请日:2020-10-19
CPC分类号: A61K9/7084 , A61K9/7061 , A61K31/56 , A61K31/57 , A61K31/56 , A61K2300/00 , A61K31/57 , A61K2300/00
摘要: A transdermal drug delivery device is disclosed. Over an extended wear period, the device causes cumulative moderate irritation plus significant irritation of less than 5% and/or achieves a meaningful degree of detachment over a seven day period of less than 20%.
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公开(公告)号:USPP35863P2
公开(公告)日:2024-06-11
申请号:US18445499
申请日:2023-08-31
CPC分类号: A01H6/7463
摘要: A new and distinct variety of peach tree (Prunus persica) is described, which is denominated varietally as ‘Wapeachseven’. This peach tree produces an attractively colored yellow-fleshed, clingstone peach that is mature for harvesting and shipment from approximately September 16 to September 28 under the ecological conditions prevailing in the San Joaquin Valley of central California.
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公开(公告)号:USD700647S1
公开(公告)日:2014-03-04
申请号:US29465321
申请日:2013-08-27
申请人: Richard Wilbern
设计人: Richard Wilbern
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公开(公告)号:US08578979B2
公开(公告)日:2013-11-12
申请号:US13469551
申请日:2012-05-11
申请人: James Johnson
发明人: James Johnson
IPC分类号: B65B3/04
CPC分类号: B67D1/0082 , B67D1/1277 , B67D3/04 , B67D7/005 , F16L29/02 , F16L37/40 , Y10T29/494 , Y10T137/0402
摘要: A collar for a dispensing connector and a fitment assembly are disclosed. The connector collar engages a valved fitment for a container for holding and dispensing fluid. The fitment includes a spout connected to the container and a sliding internal valve body and an external valve body securely positioned within the spout. The connector collar has a fitment end mateable with the fitment so as to compress the top edge of the external valve body so as to form a seal between the external valve body and the dispensing connector.
摘要翻译: 公开了用于分配连接器和配件组件的套环。 连接器套环与用于容纳和分配流体的容器的阀门配件接合。 配件包括连接到容器的喷口和滑动内部阀体以及牢固地定位在喷口内的外部阀体。 连接器套环具有可与配件配合的配件,以便压缩外部阀体的顶部边缘,从而在外部阀体和分配连接器之间形成密封。
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公开(公告)号:USD675937S1
公开(公告)日:2013-02-12
申请号:US29418118
申请日:2012-04-12
申请人: Manny Stern
设计人: Manny Stern
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公开(公告)号:US08148506B2
公开(公告)日:2012-04-03
申请号:US13168592
申请日:2011-06-24
IPC分类号: C07H21/02
CPC分类号: C12Q1/485 , C07H21/04 , C07K2319/90 , C12P21/02 , C12Q1/42 , G01N2500/10
摘要: Applicants have used protein design to develop novel functional protein architectures, termed protein kinase-inducible domains, whose structures are dependent on phosphorylation by specific protein kinases or are dependent on dephosphorylation by specific protein phosphatases. Applicants have designed kinase-inducible domains based on a modular architecture, which allows kinase-inducible domains to be responsive to any specific serine-threonine kinases. Kinase-inducible domains can consist of canonical amino acids, allowing their use as expressible tags of protein kinase activity.
摘要翻译: 申请人已经使用蛋白质设计开发新的功能蛋白质结构,称为蛋白激酶诱导结构域,其结构依赖于特异性蛋白激酶的磷酸化,或依赖于特异性蛋白磷酸酶的去磷酸化。 申请人已经设计了基于模块化结构的激酶诱导结构域,其允许激酶诱导型结构域对任何特定的丝氨酸 - 苏氨酸激酶反应。 激酶诱导型结构域可以由典型氨基酸组成,允许它们用作蛋白激酶活性的可表达标签。
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公开(公告)号:US08036399B2
公开(公告)日:2011-10-11
申请号:US12338628
申请日:2008-12-18
申请人: Chun-Chen Chao , Li-Chang Lai , Shih-Yuan Chang
发明人: Chun-Chen Chao , Li-Chang Lai , Shih-Yuan Chang
IPC分类号: H04B15/00
摘要: An audio output apparatus includes: an audio codec outputting an analog audio signal corresponding to a digital audio signal from a system controller; a switch unit having a first end coupled to the audio codec through a capacitor, and a grounded second end; and a switch controller triggered by a trigger signal to output a control signal to a control end of the switch unit such that the switch unit couples the capacitor to ground in response to the control signal. The trigger signal is generated by one of the system controller, the audio codec, and a power circuit supplying electric power to the system controller, the audio codec and the switch controller upon occurrence of a condition associated with pop noise, and is outputted to the switch controller before the pop noise is generated, such that the pop noise is conducted to ground via the switch unit.
摘要翻译: 音频输出装置包括:音频编解码器,输出对应于来自系统控制器的数字音频信号的模拟音频信号; 开关单元,其具有通过电容器耦合到音频编解码器的第一端和接地的第二端; 以及由触发信号触发的开关控制器,以将控制信号输出到开关单元的控制端,使得开关单元响应于控制信号将电容器耦合到地。 触发信号由系统控制器,音频编解码器之一产生,并且在发生与弹出噪声相关联的状况的情况下向系统控制器,音频编解码器和开关控制器提供电力的电源电路产生,并被输出到 开关控制器在产生弹跳噪声之前,使得弹出噪声通过开关单元传导到地面。
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公开(公告)号:US07919675B2
公开(公告)日:2011-04-05
申请号:US12571471
申请日:2009-10-01
申请人: Michael Godwin , Feng Han , Alec A. Hayes , Xu Hu , Soon-Chun Jeong , Guihua Lu , M. A. Saghai Maroof
发明人: Michael Godwin , Feng Han , Alec A. Hayes , Xu Hu , Soon-Chun Jeong , Guihua Lu , M. A. Saghai Maroof
CPC分类号: A01H1/04 , C07K14/415 , C12N15/8282 , C12N15/8283 , C12Q1/6895 , C12Q2600/13 , C12Q2600/156 , C12Q2600/172
摘要: The invention provides novel molecular genetic markers in soybean, where the markers are useful, for example, in the marker-assisted selection of gene alleles that impart disease-resistance, thereby allowing the identification and selection of a disease-resistant plant. The markers also find use in positional cloning of disease-resistance genes.
摘要翻译: 本发明在大豆中提供了新的分子遗传标记,其中标记可用于例如赋予抗病性的基因等位基因的标记辅助选择,从而允许鉴定和选择抗病植物。 标记也用于抗病基因的定位克隆。
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9.
公开(公告)号:US07910799B2
公开(公告)日:2011-03-22
申请号:US12512178
申请日:2009-07-30
申请人: Hong Lu , Feng Han , Scott Sebastian , Donald Kyle , Paul Stephens , Thomas C. Corbin , Jeffrey Thompson
发明人: Hong Lu , Feng Han , Scott Sebastian , Donald Kyle , Paul Stephens , Thomas C. Corbin , Jeffrey Thompson
CPC分类号: C12Q1/6895 , A01H1/04 , A01H5/10 , C12N15/8282 , C12Q2600/13 , C12Q2600/156
摘要: The invention relates to methods and compositions for identifying soybean plants that are tolerant, have improved tolerance or are susceptible to Fusarium solani infection (the causative agent of sudden death syndrome or SDS). The methods use molecular genetic markers to identify, select and/or construct disease-tolerant plants or identify and counterselect disease-susceptible plants. Soybean plants that display tolerance or improved tolerance to Fusarium solani infection that are generated by the methods of the invention are also a feature of the invention.
摘要翻译: 本发明涉及用于鉴定耐受性好,具有改善的耐受性或易受镰孢镰刀菌感染(猝死综合征或SDS的致病因子)的大豆植物的方法和组合物。 该方法使用分子遗传标记来鉴定,选择和/或构建耐病植物或识别并对抗疾病敏感植物。 通过本发明的方法产生的显示对茄病菌感染的耐受性或改善的耐受性的大豆植物也是本发明的一个特征。
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公开(公告)号:US07888323B2
公开(公告)日:2011-02-15
申请号:US11605182
申请日:2006-11-28
申请人: John D. Lambris , Madan Katragadda
发明人: John D. Lambris , Madan Katragadda
IPC分类号: A61K38/10
CPC分类号: C07K7/64 , A61K38/00 , C07K1/00 , C07K7/08 , C07K14/472
摘要: Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds.
摘要翻译: 公开了包含能够结合C3蛋白和抑制补体活化的肽和肽模拟物的化合物。 与目前可获得的化合物相比,这些化合物显示出显着改善的补体活化抑制活性。
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