公开(公告)号：US10324090B2

公开(公告)日：2019-06-18

申请号：US15037838

申请日：2014-11-21

申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA ,  Srinand Sreevatsan ,  Elise Lamont

发明人： Srinand Sreevatsan ,  Elise Lamont

IPC分类号： C12Q1/00 ,  A61K39/02 ,  A61K39/04 ,  G01N33/569 ,  G01N33/92 ,  G01N21/65

摘要： This disclosure provides a method for detecting infection of an animal by Mycobacterium bovis. The method generally includes obtaining a biological sample from a host animal at risk of being infected by Mycobacterium bovis and analyzing the sample for the presence or absence of at least one M. bovis polypeptide. In some embodiments, the method can further include analyzing the sample for the presence or absence of at least one M. bovis lipid. In some embodiments, the method can further include detecting at least one host polypeptide whose expression is greater in a host infected with M. bovis compared to expression in a host known to be uninfected with M bovis.

公开(公告)号：US10323069B2

公开(公告)日：2019-06-18

申请号：US15684358

申请日：2017-08-23

申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA

发明人： Michael Murtaugh ,  Cheryl Dvorak

IPC分类号： C07K14/005 ,  C07K17/00 ,  C07K16/10 ,  A61K39/125 ,  C12N7/00 ,  G01N33/569 ,  A61K39/12 ,  A61K39/00

摘要： A Senecavirus A polypeptide generally includes at least a portion of 151-434 of SEQ ID NO:1, amino acids 435-673 of SEQ ID NO:1, or amino acids 674-937 of SEQ ID NO:1. The Senecavirus A polypeptide may be used as a capture antigen in a method or device for detecting antibody that specifically binds to the Senecavirus A polypeptide. The Senecavirus A polypeptide may be used as a immunogen to vaccinate a subject having or at risk of having a Senecavirus A infection.

公开(公告)号：US10278435B2

公开(公告)日：2019-05-07

申请号：US14266130

申请日：2014-04-30

申请人： Regents of the University of Minnesota

发明人： Elizabeth Kersch Bye ,  Karen Louise LaBat ,  Linsey Ann Gordon ,  Theresa Elizabeth Lastovich

IPC分类号： A41B9/08 ,  A41F9/00 ,  A41D1/06 ,  A41D13/02 ,  A41D13/12 ,  A41D13/00

摘要： One or more embodiments of a protective garment and a method of manufacturing such garments are disclosed. In one or more embodiments, the protective garment can include an elastic lumbar panel attached to a rear portion of a body of the protective garment in a waist region, left and right shoulder elastic straps each including a first end attached to a front portion of the body and a second end attached to the rear portion, a left side elastic waist strap attached to the front portion and extending around a left side of the garment where it is attached to the rear portion, and a right side elastic waist strap attached to the front portion and extending around a right side of the garment where it is attached to the rear portion.

公开(公告)号：US10231712B2

公开(公告)日：2019-03-19

申请号：US13702813

申请日：2011-06-09

申请人： Emad S. Ebbini ,  Andrew J. Casper ,  Dalong Liu ,  John R. Ballard

发明人： Emad S. Ebbini ,  Andrew J. Casper ,  Dalong Liu ,  John R. Ballard

IPC分类号： A61B8/00 ,  A61B8/08 ,  A61N7/02 ,  A61N7/00

摘要： A dual-mode ultrasound system provides real-time imaging and therapy delivery using the same transducer elements of a transducer array. The system may use a multichannel driver to drive the elements of the array. The system uses a real-time monitoring and feedback image control of the therapy based on imaging data acquired using the dual-mode ultrasound array (DMUA) of transducer elements. Further, for example, multimodal coded excitation may be used in both imaging and therapy modes. Still further, for example, adaptive, real-time refocusing for improved imaging and therapy can be achieved using, for example, array directivity vectors obtained from DMUA pulse-echo data.

公开(公告)号：US10166280B2

公开(公告)日：2019-01-01

申请号：US15617541

申请日：2017-06-08

申请人： EPITOPIX LLC

发明人： Patricia E. Tam ,  Michael Nathan Harris ,  Timothy James Tripp ,  Sandra Lobo

IPC分类号： C07K1/00 ,  A61K39/07 ,  C07K14/32 ,  A61K39/00

摘要： The present invention provides isolated polypeptides isolatable from a Bacillus spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.

公开(公告)号：US10159912B2

公开(公告)日：2018-12-25

申请号：US15148454

申请日：2016-05-06

申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA

发明人： Bo Hu ,  Qiyang He

IPC分类号： B01D15/36 ,  B01J41/12 ,  C07C29/76 ,  B01D15/20 ,  C07F9/117 ,  C12F3/00 ,  C12F3/10 ,  B01J49/07 ,  B01J49/57

摘要： Methods of processing distillates, methods of removing at least some portion of total phosphorus in a distillate, methods of removing at least some portion of the soluble inorganic phosphorus, phytate phosphorus, or some combination thereof in a distillate, methods for obtaining phytate from distillates, methods for producing phytate derivatives and combinations thereof.

公开(公告)号：US10119027B2

公开(公告)日：2018-11-06

申请号：US15125380

申请日：2015-03-13

申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA

发明人： Yi-ru Chen-Sarkanen ,  Simo Sarkanen ,  Yun-Yan Wang

IPC分类号： C08L97/00 ,  C08H7/00 ,  C08K5/07 ,  C08K5/136

摘要： Disclosed herein are compositions that include at least about 75 weight percent (wt %) alkylated lignin based on the total weight of the composition without any solvent(s). The material having a tensile strength of at least about 35 MPa, an elongation-to-break of at least about 1.5%, or both. Articles including such materials and methods of forming the same are also disclosed.

公开(公告)号：US10005077B2

公开(公告)日：2018-06-26

申请号：US14130589

申请日：2012-07-03

申请人： Michael Tsapatsis ,  Kumar Varoon Agrawal

发明人： Michael Tsapatsis ,  Kumar Varoon Agrawal

IPC分类号： B01J31/26 ,  B01D53/22 ,  B01D67/00 ,  B01D69/12 ,  B01D71/02 ,  C01B39/02 ,  B01J37/02 ,  C08K3/34 ,  C30B29/16 ,  B82Y30/00 ,  B82Y40/00

CPC分类号： B01J31/26 ,  B01D53/228 ,  B01D67/0046 ,  B01D67/0051 ,  B01D67/0076 ,  B01D69/12 ,  B01D71/024 ,  B01D71/027 ,  B01D71/028 ,  B01D2323/08 ,  B01D2325/04 ,  B01J37/0215 ,  B01J2231/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01B39/026 ,  C08K3/34 ,  C30B29/16

摘要： Oxide materials, thin films, coatings, and methods of preparing the same are disclosed herein. In certain embodiments the oxide material can have an MWW type framework or an MFI type framework. In one embodiment, the method includes: providing a suspension of an exfoliated layered oxide material in a solvent; and filtering the suspension through a porous support to provide a film of the oxide material, optionally directly on the porous support. Secondary grown films of the oxide material and methods of preparing the same are also provided. Thin zeolite films are attractive for a wide range of applications including molecular sieve membranes and catalytic membrane reactors, permeation barriers, low dielectric constant materials for microelectronics and sensor components for selective sensing.

公开(公告)号：US09796993B2

公开(公告)日：2017-10-24

申请号：US14364448

申请日：2012-12-12

申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA

发明人： Yi-ru Chen-Sarkanen ,  Simo Sarkanen ,  Yun-Yan Wang

IPC分类号： C12P19/14 ,  C12P19/02 ,  C12P19/00

CPC分类号： C12P19/02 ,  C12P19/00 ,  C12P19/14

摘要： A method involving degrading materials that include lignin generally includes contacting a lignin sample with a flavin-dependent monooxygenase and contacting the lignin sample with an auxiliary compound.

公开(公告)号：US09796957B2

公开(公告)日：2017-10-24

申请号：US15067802

申请日：2016-03-11

申请人： Brett Barney ,  Carolann Marie Knutson ,  Mary Plunkett

发明人： Brett Barney ,  Carolann Marie Knutson ,  Mary Plunkett

IPC分类号： C12N1/20 ,  C12R1/065 ,  C07K14/21 ,  C12N9/80

CPC分类号： C12N1/20 ,  C07K14/21 ,  C12N9/80 ,  C12R1/065

摘要： This disclosure describes a genetically-modified diazotrophic microbe and methods that involve the genetically-modified diazotrophic microbe. Generally, the diazotrophic microbe is modified to excrete a nitrogen-containing compound in an amount greater than a comparable control diazotrophic microbe. The genetically-modified diazotrophic microbe can be co-cultured with a non-diazotroph and increase the growth of the non-diazotroph.