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113 条记录 (耗时 0.025 秒)

    Nucleotide sequences encoding the ptsH gene
    81.
    发明授权
    Nucleotide sequences encoding the ptsH gene 有权
    编码ptsH基因的核苷酸序列

    公开(公告)号：US06818432B2

    公开(公告)日：2004-11-16

    申请号：US09819930

    申请日：2001-03-29

    申请人： Mike Farwick ,  Bettina Mockel ,  Walter Pfefferle

    发明人： Mike Farwick ,  Bettina Mockel ,  Walter Pfefferle

    IPC分类号： C12N120

    CPC分类号： C12N9/1205 ,  C12P13/04 ,  C12P13/08

    摘要： The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group comprising a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polynucleotide which codes for a polypeptide containing an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no.2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative production of L-amino acids with enhancement of the ptsH gene coding for component H of the phosphotransferase system, and the use of the above polynucleotides as primer or hybridisation probe.

    摘要翻译： 本发明涉及含有多核苷酸序列的分离的多核苷酸，所述多核苷酸序列选自包含a）多核苷酸的多核苷酸，所述多核苷酸与编码含有SEQ ID NO：1的氨基酸序列的多肽的多核苷酸具有至少70％的同一性。 2，b）编码含有与SEQ ID No.2的氨基酸序列至少70％相同的氨基酸序列的多肽的多核苷酸，c）与a）或b）的多核苷酸互补的多核苷酸， 和d）多核苷酸，其包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸，以及用于增强编码磷酸转移酶系统的组分H的ptsH基因的L-氨基酸的发酵生产的方法， 以及使用上述多核苷酸作为引物或杂交探针。

    Process for the enzymatic production of D-pantothenic acid and/or its salts
    83.
    发明授权
    Process for the enzymatic production of D-pantothenic acid and/or its salts 失效
    用于酶促生产D-泛酸和/或其盐的方法

    公开(公告)号：US06689592B2

    公开(公告)日：2004-02-10

    申请号：US10052270

    申请日：2002-01-23

    申请人： Mechthild Rieping ,  Thomas Hermann ,  Walter Pfefferle

    发明人： Mechthild Rieping ,  Thomas Hermann ,  Walter Pfefferle

    IPC分类号： C12P100

    CPC分类号： C12P13/02 ,  A23K20/174 ,  C12N15/52

    摘要： A process for the enzymatic production of D-pantothenic acid and/or its salts or feedstuffs additives containing the latter by fermentation of microorganisms of the family Enterobacteriaceae, in particular those that already produce D-pantothenic acid, wherein the nucleotide sequence(s) coding for the serC gene is/are enhanced, in particular overexpressed, in the microorganisms.

    摘要翻译： 通过发酵肠杆菌科的微生物，特别是已经产生D-泛酸的微生物的酶促生产D-泛酸和/或其盐或饲料添加剂的方法，其中编码的核苷酸序列 因为serC基因在微生物中被增强，特别是过表达。