公开(公告)号：US20150328377A1

公开(公告)日：2015-11-19

申请号：US14758099

申请日：2013-12-31

Applicant: BACTERIN INTERNATIONAL, INC.

Inventor： Mark SCHALLENBERGER

IPC: A61L31/16 ,  A01N47/44 ,  A01N43/90 ,  A61L31/10 ,  A61L31/08 ,  A61L31/14 ,  A61L27/28 ,  A61L27/54 ,  A01N37/36 ,  A01N37/18

CPC classification number: A61L31/16 ,  A01N37/18 ,  A01N37/36 ,  A01N43/90 ,  A01N47/44 ,  A61L27/18 ,  A61L27/28 ,  A61L27/54 ,  A61L27/58 ,  A61L31/08 ,  A61L31/10 ,  A61L31/148 ,  A61L2300/206 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2300/45 ,  C09D5/14 ,  C08L67/04

Abstract: The present invention relates to an antimicrobial composition, which is a synergistic combination comprising an anti-microbial agent and a polymer or monomer comprising D-alpha hydroxy acid or a polymer capable of releasing a D-alpha hydroxy acid monomer. The present invention also relates to methods for using and applying the same.

Abstract translation: 本发明涉及一种抗微生物组合物，其是包含抗微生物剂和包含D-α羟基酸或能够释放D-α羟基酸单体的聚合物的聚合物或单体的协同组合。 本发明还涉及使用和应用该方法。

公开(公告)号：US09163064B1

公开(公告)日：2015-10-20

申请号：US14692518

申请日：2015-04-21

Applicant: Centaur, Inc.

Inventor： Luis Tonatiuh Melgarejo Garcia ,  Annika Linde ,  Gerald Henry Lushington

IPC: A01N37/18 ,  A61K38/04 ,  C07K7/08

CPC classification number: C07K7/08 ,  A01N37/46 ,  A01N47/44 ,  A01N63/02 ,  A61K38/00 ,  C07K14/47

Abstract: The present disclosure relates to antimicrobial agents and methods of using such agents. The disclosure includes antimicrobial agents having broad spectrum antimicrobial activity, nucleic acids and amino acid sequences encoding such antimicrobial agents, as well as methods of using the antimicrobial agents. The antimicrobial agents of the disclosure may be used to reduce survival of a microbe, as an antimicrobial therapeutic, in microbial treatment protocols, and in research, as well as other uses related to reducing microbe survival. In addition, the disclosure also includes compositions, as well as articles of manufacture, that comprise a broad spectrum antimicrobial agent.

Abstract translation: 本公开涉及抗微生物剂及其使用方法。 本公开内容包括具有广谱抗微生物活性的抗微生物剂，编码这种抗微生物剂的核酸和氨基酸序列，以及使用抗微生物剂的方法。 本公开的抗微生物剂可用于在微生物处理方案中以及与减少微生物存活相关的研究以及其它用途中减少作为抗微生物治疗剂的微生物的存活。 此外，本公开还包括包含广谱抗微生物剂的组合物以及制品。

公开(公告)号：US09149044B2

公开(公告)日：2015-10-06

申请号：US14009193

申请日：2012-04-13

Applicant: Palle Pedersen ,  Clifford George Watrin ,  Michael Oostendorp ,  Andre Luiz-Freitas de Oliveira

Inventor： Palle Pedersen ,  Clifford George Watrin ,  Michael Oostendorp ,  Andre Luiz-Freitas de Oliveira

IPC: A01N63/02 ,  A01N63/00 ,  A01N51/00

CPC classification number: A01N63/00 ,  A01N47/44 ,  A01N63/02 ,  Y02A50/356 ,  A01N2300/00 ,  A01N51/00

Abstract: Combinations suitable for agricultural use can include (I) a nematode-antagonistic biocontrol agent and (II) one or more agents selected, independently of each other, from any one of (A) to (H): (A) at least one fungicide; (B) at least one insecticide; (C) at least one synthetic nematicide; (D) bacterium of the genus Bacillus; (E) Harpin; (F) Isoflavones; (G) Plant growth regulators; and/or (H) Plant activators.

Abstract translation: 适合农业的组合可以包括（I）线虫 - 拮抗生物防治剂和（II）从（A）至（H）中任一个彼此独立地选择的一种或多种药剂：（A）至少一种杀真菌剂 ; （B）至少一种杀虫剂; （C）至少一种合成杀线虫剂; （D）芽孢杆菌属细菌; （E）Harpin; （F）异黄酮; （G）植物生长调节剂; 和/或（H）植物活化剂。

公开(公告)号：US20150272124A1

公开(公告)日：2015-10-01

申请号：US14225039

申请日：2014-03-25

Applicant: Ecolab USA Inc.

Inventor： Daniel E. Pedersen ,  Carter M. Silvernail ,  Kerrie E. Walters ,  Hilina Emiru

IPC: A01N47/44 ,  A61K8/41 ,  A61K8/43 ,  A01N25/30 ,  A61K8/81 ,  A61K8/60 ,  A61Q19/10 ,  A61Q19/00 ,  A01N33/12 ,  A61K8/34

CPC classification number: A61K8/43 ,  A01N25/16 ,  A01N25/30 ,  A01N33/12 ,  A01N47/44 ,  A61K8/345 ,  A61K8/41 ,  A61K8/416 ,  A61K8/602 ,  A61K8/8158 ,  A61K2800/30 ,  A61K2800/54 ,  A61K2800/74 ,  A61Q17/005 ,  A61Q19/00 ,  A61Q19/10

Abstract: The antimicrobial composition of the present invention comprises a cationic active ingredient, a foam boosting surfactant, a foam boosting copolymer, a foam stabilizer, and a chelating agent. The present antimicrobial compositions are free of the antimicrobial agent triclosan (i.e., 2,4,4′-trichloro-2′hydroxy-diphenylether), have rapid cidal activity, provide stable copious foam and exhibit enhanced tissue (e.g. skin) compatibility as defined by an in vitro whole toxicology assessment method.

Abstract translation: 本发明的抗微生物组合物包含阳离子活性成分，泡沫促进表面活性剂，泡沫促进共聚物，泡沫稳定剂和螯合剂。 本发明的抗微生物组合物不含抗菌剂三氯生（即2,4,4'-三氯-2'-羟基 - 二苯基醚），具有快速的杀虫活性，提供稳定的大量泡沫，并表现出如所定义的增强的组织（例如皮肤）相容性 通过体外全毒理学评估方法。

公开(公告)号：US20150264922A1

公开(公告)日：2015-09-24

申请号：US14711245

申请日：2015-05-13

Applicant: THE CLOROX COMPANY

Inventor： David R. Scheuing ,  Travers Anderson ,  Thomas F. Fahlen ,  William L. Smith ,  Erika Szekeres ,  Rui Zhang

IPC: A01N25/30 ,  A01N47/44 ,  A01N33/12

CPC classification number: A01N25/30 ,  A01N33/12 ,  A01N47/44 ,  A01N25/00 ,  A01N25/04 ,  A01N25/10

Abstract: The invention relates to polymer-micelle complex. The polymer-micelle complexes include a positively charged micelle selected from the group consisting of a monomeric quaternary ammonium compound, a monomeric biguanide compound, and mixtures thereof. The positively charged micelle is electrostatically bound to a water-soluble polymer bearing a negative charge. The polymer does not comprise block copolymer, latex particles, polymer nanoparticles, cross-linked polymers, silicone copolymer, fluorosurfactant, or amphoteric copolymer. The compositions do not form a coacervate, and do not form a film when applied to a surface.

Abstract translation: 本发明涉及聚合物 - 胶束复合物。 聚合物 - 胶束复合物包括选自单体季铵化合物，单体双胍化合物及其混合物的带正电荷的胶束。 带正电的胶束静电结合到带有负电荷的水溶性聚合物上。 聚合物不包含嵌段共聚物，胶乳颗粒，聚合物纳米颗粒，交联聚合物，硅氧烷共聚物，含氟表面活性剂或两性共聚物。 组合物不形成凝聚层，并且当施加到表面时不形成膜。

公开(公告)号：US09131698B2

公开(公告)日：2015-09-15

申请号：US14125095

申请日：2012-05-08

Applicant: Bei Yin

Inventor： Bei Yin

IPC: A01N25/34 ,  A01N25/00 ,  A01N57/00 ,  A61K31/66 ,  A01N47/10 ,  A61K31/27 ,  A01N33/00 ,  A01N57/20 ,  A01N47/44

CPC classification number: A01N57/20 ,  A01N47/44 ,  A01N2300/00

Abstract: Provided are biocidal compositions comprising: a hydroxymethyl-substituted phosphorus compound and a polymeric biguanide. The compositions are useful for controlling microorganisms in aqueous or water-containing systems.

Abstract translation: 提供的杀生物组合物包含：羟甲基取代的磷化合物和聚合双胍。 该组合物可用于控制含水或含水体系中的微生物。

公开(公告)号：US20150232521A1

公开(公告)日：2015-08-20

申请号：US14609128

申请日：2015-01-29

Applicant: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center

Inventor： Michael R. YEAMAN ,  Nannette Y. YOUNT ,  Eric P. BRASS

IPC: C07K14/47 ,  C12N7/00 ,  A01N47/44 ,  C07K14/005

CPC classification number: C07K14/47 ,  A01N47/44 ,  A61K47/6415 ,  C07K14/005 ,  C07K14/4747 ,  C12N7/00 ,  C12N2795/10031

Abstract: The invention provide isolated peptides, protides and conjugates having novel peptide sequences which are able to induce antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity. The invention also provides a method of inducing programmed cell death in a cell by contacting the cell with an isolated peptide, protide or conjugate described herein. In some aspects, the method can be used in the diagnosis, prevention, or treatment of a disease, such as an infection, cancer, autoimmune disease, or inflammatory disease.

Abstract translation: 本发明提供具有能够诱导抗微生物，抗癌，抗炎，抗增殖或程序性细胞死亡活性的新肽序列的分离的肽，抗原和缀合物。 本发明还提供了通过使细胞与本文所述的分离的肽，抗原或缀合物接触来诱导细胞中程序性细胞死亡的方法。 在某些方面，该方法可用于诊断，预防或治疗诸如感染，癌症，自身免疫性疾病或炎性疾病的疾病。

公开(公告)号：US20150223464A1

公开(公告)日：2015-08-13

申请号：US14615552

申请日：2015-02-06

Applicant: GOJO INDUSTRIES, INC.

Inventor： James Edmund Bingham ,  David R. Macinga

IPC: A01N47/44 ,  A01N47/28 ,  A01N31/02

CPC classification number: A01N31/02 ,  A01N37/02 ,  A01N37/04 ,  A01N43/16 ,  A01N47/28 ,  A01N47/44 ,  A01N59/00 ,  C11D3/2003 ,  C11D3/48 ,  C11D7/261

Abstract: Compositions and methods for the disinfection of surfaces are provided. The compositions include at least about 40 weight percent of a C1-6 alcohol, and a primary enhancer selected from protein denaturants. The disinfectant composition is characterized by a pH of less than about 3. Broad spectrum efficacy is achieved, and synergistic activity is exhibited against C. difficile spores.

Abstract translation: 提供了表面消毒的组合物和方法。 组合物包含至少约40重量％的C 1-6醇，和选自蛋白质变性剂的主要增强剂。 消毒剂组合物的特征在于pH小于约3。实现了广谱功效，并且对艰难梭菌孢子表现出协同活性。

公开(公告)号：US09095137B2

公开(公告)日：2015-08-04

申请号：US10590309

申请日：2005-02-21

Applicant: Yuichi Ohkawara

Inventor： Yuichi Ohkawara

IPC: A01N43/40 ,  A01P7/04 ,  A01N43/56

CPC classification number: A01N43/56 ,  A01N43/50 ,  A01N47/44 ,  A01N51/00 ,  A01N47/40 ,  A01N2300/00

Abstract: Insecticide compositions which comprise one or not less than two kinds of compounds being selected from a compound represented by the formula [I]: or a salt thereof, and a neonicotinoid compound represented by the formula [II]: The insecticide compositions can produce higher insecticidal effects than would be expected when each of the active ingredients is used singly, namely a synergistic effect, thus enabling reductions in the rate or number of application of agrochemicals and pesticides to be realized.

Abstract translation: 选自由式[I]表示的化合物或其盐的一种或不少于两种化合物的杀虫剂组合物和由式[II]表示的新烟碱类化合物：杀虫剂组合物可以产生更高的杀虫剂 当每种活性成分单独使用时即预期的效果，即协同效应，从而能够降低要实现的农药和农药的使用速率或数量。

公开(公告)号：US20150164077A1

公开(公告)日：2015-06-18

申请号：US14402984

申请日：2013-05-22

Applicant: Dow Global Technologies LLC ,  Rohm and Haas Company

Inventor： Emerentiana Sianawati ,  Jon B. Raymond

IPC: A01N43/80 ,  A01N43/40 ,  A01N33/20 ,  A01N43/70 ,  A01N43/32 ,  A01N47/44 ,  A01N31/08

CPC classification number: A01N43/80 ,  A01N31/08 ,  A01N33/20 ,  A01N43/32 ,  A01N43/40 ,  A01N43/70 ,  A01N47/44

Abstract: Synergistic microbicidal compositions containing N-methyl-1,2-benzisothiazolin-3-one and dodecylguanidine, poly(hexamethylene biguanide hydrochloride), sodium pyrithione, sodium ortho-phenylphenate, terbutryn, dimethoxane or 2-(hydroxymethyl)-2-nitropropane-1,3-diol.

Abstract translation: 含有N-甲基-1,2-苯并异噻唑啉-3-酮和十二烷基胍的协同杀菌组合物，聚（六亚甲基双胍盐酸盐），吡啶硫酮钠，邻苯基苯甲酸钠，叔丁基二甲氧基硅烷或2-（羟甲基）-2-硝基丙烷-1 ，3-二醇。