End of service life indicator for organic vapor respirator filter cartridge
    72.
    发明授权
    End of service life indicator for organic vapor respirator filter cartridge 有权
    有机蒸汽呼吸器滤芯使用寿命指示器

    公开(公告)号:US08859995B2

    公开(公告)日:2014-10-14

    申请号:US13536019

    申请日:2012-06-28

    IPC分类号: G01J1/58

    摘要: Embodiments generally relate to detection of end of service life for respirator filter cartridges for organic vapor(s). Typically, detection of end of service life might use a competitive UV absorbance-fluorescence approach. Thus, a sensor that emits light upon application of UV may be placed within the cartridge, with a UV lamp and a light detector directed at the sensor. In some embodiments, a plurality of corresponding sensor and UV lamp and light detector might be used. Typically, the light level emitted by the sensor(s) might be used to estimate effective end of service life.

    摘要翻译: 实施例通常涉及用于有机蒸气的呼吸器滤芯的使用寿命终止的检测。 通常,检测使用寿命可能会使用竞争性的紫外吸收 - 荧光法。 因此,在施加UV时发出光的传感器可以被放置在盒内,UV灯和指向传感器的光检测器。 在一些实施例中,可以使用多个对应的传感器和UV灯和光检测器。 通常,由传感器发射的光级可用于估计有效的使用寿命。

    Closed loop optimization of A-V and V-V timing
    73.
    发明授权
    Closed loop optimization of A-V and V-V timing 有权
    闭环优化A-V和V-V定时

    公开(公告)号:US08755882B2

    公开(公告)日:2014-06-17

    申请号:US12962245

    申请日:2010-12-07

    申请人: Li Wang

    发明人: Li Wang

    摘要: Embodiments of close loop optimization of atrio-ventricular (A-V) delay interval and/or inter-ventricular (V-V) timing are disclosed. An implantable medical device includes a housing that supports a processing means adapted for implantation in a patient. There can be two or more electrodes electrically coupled to the processing means where the two or more electrodes can be used for sensing a patient's cardiac signals, which include a far-field EGM. The processing means can determine a width of a P-wave from the sensed far-field EGM. Also included can be a means for delivering an adapted cardiac pacing therapy based upon the width of the P-wave, including revised A-V delay and/or V-V temporal intervals.

    摘要翻译: 公开了房室(A-V)延迟间隔和/或心室间(V-V)定时的闭环优化的实施例。 可植入医疗装置包括支撑适于植入患者体内的处理装置的外壳。 可以有两个或更多个电极耦合到处理装置的电极,其中两个或更多个电极可用于感测患者的心脏信号,其包括远场EGM。 处理装置可以从感测的远场EGM确定P波的宽度。 还包括可以用于基于P波的宽度(包括修正的A-V延迟和/或V-V时间间隔)递送适应的心脏起搏治疗的手段。

    Method for making sulfur-graphene composite material
    75.
    发明授权
    Method for making sulfur-graphene composite material 有权
    制备硫 - 石墨烯复合材料的方法

    公开(公告)号:US08609183B2

    公开(公告)日:2013-12-17

    申请号:US13545170

    申请日:2012-07-10

    IPC分类号: B05D5/12

    摘要: A method for making sulfur-graphene composite material is disclosed. In the method, a dispersed solution including a solvent and a plurality of graphene sheets dispersed in the solvent is provided. A sulfur-source chemical compound is dissolved into the dispersed solution to form a mixture. A reactant, according to the sulfur-source chemical compound, is introduced to the mixture. Elemental sulfur is produced on a surface of the plurality of graphene sheets due to a redox reaction between the sulfur-source chemical compound and the reactant, to achieve the sulfur-graphene composite material. The sulfur-graphene composite material is separated from the solvent.

    摘要翻译: 公开了制备硫 - 石墨烯复合材料的方法。 在该方法中,提供了包含溶剂和分散在溶剂中的多个石墨烯片的分散溶液。 将硫源化合物溶解在分散溶液中以形成混合物。 将根据硫源化合物的反应物引入混合物中。 由于硫源化合物和反应物之间的氧化还原反应,在多个石墨烯片的表面上产生元素硫,以实现硫 - 石墨烯复合材料。 硫 - 石墨烯复合材料与溶剂分离。

    METHODS AND APAPRATUS FOR MANUALLY SUSPENDING INTRATHORACIC IMPEDANCE FLUID STATUS MEASUREMENTS
    77.
    发明申请
    METHODS AND APAPRATUS FOR MANUALLY SUSPENDING INTRATHORACIC IMPEDANCE FLUID STATUS MEASUREMENTS 审中-公开
    用于手动停止静脉内阻滞流体状态测量的方法和APAPRATUS

    公开(公告)号:US20120303085A1

    公开(公告)日:2012-11-29

    申请号:US13570858

    申请日:2012-08-09

    IPC分类号: A61N1/365

    摘要: The capability to suspend a patient alert relating to a monitored physiologic parameters addresses a need to selectively shut off a patient-alert signal or signals during the time a patient is being treated for an excursion in the parameter. Of course, in general a signal call attention to a patient's a potentially deleterious status or condition for which they should seek medical attention. Once a chronically-implanted monitoring device has detected or provided information about the parameter relative to a desired value, trend, or range and a clinician has been notified and intervened the alert signal is temporarily disabled for a predetermined period. That is, once the notification occurs and alert has served its purpose, the alert mechanism is selectively deactivated while the patient ostensibly begins to gradually correct the monitored physiologic parameter under a caregiver's direction and control. After which time, the alert will reactivate.

    摘要翻译: 暂停与所监测的生理参数相关的患者警报的能力解决了在患者被治疗参数期间偏移的时间期间选择性地切断病人警报信号或信号的需要。 当然,一般来说,一个信号会引起对患者的一个潜在的有害的状态或状况的关注,他们应该寻求医疗护理。 一旦长期植入的监测装置已经相对于期望值,趋势或范围已经检测或提供了关于参数的信息,并且已通知临床医生并且中介了警报信号暂时禁用预定时间段。 也就是说,一旦通知发生并且警报已经达到其目的,则警告机制被选择性地去激活,同时患者表面上开始逐渐校正受照顾者的方向和控制下的监测的生理参数。 之后,警报将重新启动。

    REGULATORY T CELL MEDIATOR PROTEINS AND USES THEREOF
    78.
    发明申请
    REGULATORY T CELL MEDIATOR PROTEINS AND USES THEREOF 有权
    调节性T细胞介质蛋白及其用途

    公开(公告)号:US20120301484A1

    公开(公告)日:2012-11-29

    申请号:US13546098

    申请日:2012-07-11

    IPC分类号: C07K16/28 A61K39/395

    摘要: The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates αCD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon αCD3/αGITR stimulation. This protein has been designated Treg-sTNF. Proteins, antibodies, activated T cells and methods for using the same are disclosed.In particular methods of using these proteins and compounds, preferably antibodies, which bind or modulate (agonize or antagonize) the activity of these proteins, as immune modulators and for the treatment of cancer, autoimmune disease, allergy, infection and inflammatory conditions, e.g. multiple sclerosis is disclosed

    摘要翻译: 本发明涉及新型调节性T细胞蛋白。 称为PD-L3的一种蛋白质类似于PD-L1家族的成员,并且在体外共同刺激T细胞的αCD3增殖。 第二种TNF样蛋白也被鉴定为在αCD3/αGITR刺激下上调。 该蛋白质已被命名为Treg-sTNF。 公开了蛋白质,抗体,活化的T细胞和使用它们的方法。 特别是使用这些蛋白质和化合物(优选抗体)的方法,其结合或调节(激动或拮抗)这些蛋白质的活性,作为免疫调节剂和用于治疗癌症,自身免疫疾病,变态反应,感染和炎性病症,例如, 公开了多发性硬化

    METHOD AND APPARATUS FOR IMPROVING POWER OUTPUT EFFICIENCY OF LINE DRIVER
    79.
    发明申请
    METHOD AND APPARATUS FOR IMPROVING POWER OUTPUT EFFICIENCY OF LINE DRIVER 有权
    提高线路驱动器功率输出效率的方法和装置

    公开(公告)号:US20120294438A1

    公开(公告)日:2012-11-22

    申请号:US13565532

    申请日:2012-08-02

    IPC分类号: H04M9/00

    CPC分类号: H04M11/062

    摘要: A method and an apparatus for improving power output efficiency of a line driver are disclosed. The method includes: obtaining a current working parameter of an xDSL subscriber board, where the current working parameter includes at least one of a working mode configured on a subscriber port of the xDSL subscriber board and current output power of the subscriber port; and determining, according to the current working parameter, a control signal for a line driver in the xDSL subscriber board and outputting the control signal.

    摘要翻译: 公开了一种用于提高线路驱动器的功率输出效率的方法和装置。 该方法包括:获取xDSL用户板的当前工作参数,其中当前工作参数包括在xDSL用户板的用户端口上配置的工作模式和用户端口的当前输出功率中的至少一个; 以及根据当前工作参数确定xDSL用户板中的线路驱动器的控制信号并输出​​该控制信号。