公开(公告)号：US20050215939A1

公开(公告)日：2005-09-29

申请号：US11137808

申请日：2005-05-25

申请人： Jessica Lemay ,  Dane Jackson ,  Michael Miller ,  Wayne Melvin

发明人： Jessica Lemay ,  Dane Jackson ,  Michael Miller ,  Wayne Melvin

IPC分类号： A61F13/26 ,  A61F13/20

CPC分类号： A61F13/26 ,  Y10S604/904 ,  Y10T156/10 ,  Y10T156/1038

摘要： There is provided a multiple-component tampon applicator formed from at least three separate components. A fingergrip having a reduced cross-section as compared to that of the barrel may be formed such that it is a separate component or is integrally formed with a barrel component. The reduced cross-section fingergrip provides exceptional grippability to the user. The multiple components may be formed from materials including, for example, biopolymer including starches and proteins, cardboard, heat shrink plastic, paper slurry, plastic, plastic tubing, pulp slurry, pulp-molded paper, or any combinations thereof. Prior to assembly of the applicator and prior to loading the barrel component with an absorbent pledget, petals may be formed on the insertion end of the barrel using existing processes and equipment. Alternatively, a separate insertion tip component having petals may be formed. This separate component may then be connected to the barrel component either before or after an absorbent pledget is loaded into the barrel component.

公开(公告)号：US20050192421A1

公开(公告)日：2005-09-01

申请号：US10789319

申请日：2004-02-27

申请人： Frank Xu ,  Michael Miller ,  Michael Watts

发明人： Frank Xu ,  Michael Miller ,  Michael Watts

IPC分类号： C08L83/04 ,  C08L83/06

CPC分类号： B82Y10/00 ,  B82Y40/00 ,  G03F7/0002

摘要： The present invention includes a composition for a silicon-containing material used as an etch mask for underlying layers. More specifically, the silicon-containing material may be used as an etch mask for a patterned imprinted layer comprising protrusions and recessions. To that end, in one embodiment of the present invention, the composition includes a hydroxyl-functional silicone component, a cross-linking component, a catalyst component, and a solvent. This composition allows the silicon-containing material to selectively etch the protrusions and the segments of the patterned imprinting layer in superimposition therewith, while minimizing the etching of the segments in superposition with the recessions, and therefore allowing an in-situ hardened mask to be created by the silicon-containing material, with the hardened mask and the patterned imprinting layer forming a substantially planarized profile.

摘要翻译： 本发明包括用作下层的蚀刻掩模的含硅材料用组合物。 更具体地，含硅材料可以用作包括突起和凹陷的图案化印记层的蚀刻掩模。 为此，在本发明的一个实施方案中，组合物包括羟基官能的硅氧烷组分，交联组分，催化剂组分和溶剂。 该组合物允许含硅材料与图案化压印层的突起和段的叠加选择性地蚀刻，同时最小化与凹陷叠加的段的蚀刻，并且因此允许形成原位硬化的掩模 通过含硅材料，硬化的掩模和图案化的压印层形成基本平坦化的轮廓。

公开(公告)号：US20050172199A1

公开(公告)日：2005-08-04

申请号：US10772034

申请日：2004-02-03

申请人： Michael Miller ,  Lyman Horne ,  W. Willes ,  Douglas Grover

发明人： Michael Miller ,  Lyman Horne ,  W. Willes ,  Douglas Grover

IPC分类号： G08C25/02 ,  H04L1/08 ,  H04L1/16 ,  H04L1/18

CPC分类号： H04L1/188 ,  H04L1/08 ,  H04L1/16 ,  H04L1/1819

摘要： A data networking system designed to provide efficient yet reliable transportation of data across a time division multiplexed network. This invention allows for redundantly sending and resending of segments in a dynamic manner. In addition, segments are fragmented, resized and sent with low overhead due to dynamic header sizes, segment sizes, forward error correction, and cyclic redundancy checks. The result is a very adaptive network that meets the demanding requirements of networks such as power line and wireless while still being able to transport data for voice, audio, video, computer, control, and the like.

摘要翻译： 一种数据网络系统，旨在通过时分复用网络提供高效可靠的数据传输。 本发明允许以动态方式冗余地发送和重新发送段。 另外，由于动态报头大小，段大小，前向纠错和循环冗余检查，段被分段，调整大小并以低开销发送。 结果是一个非常适合的网络，满足诸如电力线和无线等网络的苛刻要求，同时仍然能够传输语音，音频，视频，计算机，控制等数据。

公开(公告)号：US20050099426A1

公开(公告)日：2005-05-12

申请号：US10703748

申请日：2003-11-07

申请人： Bruno Primerano ,  Michael Miller ,  Michael Murdoch

发明人： Bruno Primerano ,  Michael Miller ,  Michael Murdoch

IPC分类号： G09G3/20 ,  G09G3/32 ,  G09G5/02 ,  H04N1/60

CPC分类号： H04N1/6022 ,  G09G3/20 ,  G09G3/3208 ,  G09G5/02 ,  G09G2300/0452 ,  G09G2320/02

摘要： A method for transforming three color input signals (R, G, B) corresponding to three gamut defining color primaries to four color output signals (R′, G′, B′, W) corresponding to the gamut defining color primaries and one additional color primary W for driving a display having emitters that emit light corresponding to the to the four color output signals including calculating a common signal value S as a function F1 of the three color input signals (R,G,B) for a current and neighboring pixels; determining a final common signal value S′ based upon the common signals for the current and neighboring pixels; calculating the three color signals (R′,G′,B′) by calculating a value of a function F2 of the final common signal value S′ and adding it to each of the three color input signals (R,G,B); and calculating the output signal W as a function F3 of the final common signal value S′.

摘要翻译： 将对应于三个色域定义颜色原色的三色输入信号（R，G，B）变换为与定义颜色原色的色域对应的四色输出信号（R'，G'，B'，W）的一种方法， 用于驱动具有发射与四色输出信号相对应的光的显示器的显示器W，包括计算用于当前和相邻的三色输入信号（R，G，B）的函数F 1的公共信号值S 像素; 基于当前和相邻像素的公共信号确定最终公共信号值S'; 通过计算最终公共信号值S'的函数F 2的值并将其相加到三个颜色输入信号（R，G，B）中的每一个来计算三色信号（R'，G'，B'）， ; 并计算输出信号W作为最终公共信号值S'的函数F 3。

公开(公告)号：US20050085513A1

公开(公告)日：2005-04-21

申请号：US10963711

申请日：2004-10-14

申请人： Erkan Baloglu ,  Michael Miller ,  Ravi Chari

发明人： Erkan Baloglu ,  Michael Miller ,  Ravi Chari

IPC分类号： A61K31/337 ,  A61P31/04 ,  A61P31/12 ,  A61P33/00 ,  A61P35/00 ,  A61P37/06 ,  A61P43/00 ,  C07D305/14 ,  C07D407/12 ,  C07D407/14 ,  C07D409/12 ,  A61K31/4025 ,  A61K31/4433 ,  C07D45/02

CPC分类号： C07D407/12 ,  A61K31/337 ,  C07D305/14 ,  C07D407/14 ,  C07D409/12 ,  Y02A50/423 ,  Y02A50/491

摘要： Included within the scope of the present invention are potent taxanes and taxanes containing a linking group. Also included is a cytotoxic agent comprising one or more taxanes linked to a cell binding agent. A therapeutic composition for inducing cell death in selected cell populations comprising: (A) a cytotoxic amount of one or more taxanes covalently bonded to a cell binding agent through a link, and (B) a pharmaceutically acceptable carrier, diluent or excipient is also included. A method for inducing cell death in selected cell populations comprising contacting target cells or tissue containing target cells with an effective amount of a cytotoxic agent comprising one or more taxanes linked to a cell binding agent is included as well.

摘要翻译： 包括在本发明范围内的有效的紫杉烷类和含有连接基团的紫杉烷类。 还包括细胞毒性剂，其包含与细胞结合剂连接的一种或多种紫杉烷类。 一种用于在所选细胞群体中诱导细胞死亡的治疗组合物，包括：（A）细胞毒性量的一种或多种通过连接体与细胞结合剂共价结合的紫杉烷，和（B）药学上可接受的载体，稀释剂或赋形剂 。 还包括诱导选择的细胞群体中的细胞死亡的方法，包括使靶细胞或含有靶细胞的组织与有效量的包含与细胞结合剂连接的一种或多种紫杉烷的细胞毒性试剂接触。

公开(公告)号：US20050065393A1

公开(公告)日：2005-03-24

申请号：US10984164

申请日：2004-11-09

申请人： Michael Miller

发明人： Michael Miller

IPC分类号： A61B17/34 ,  A61M36/12 ,  A61N5/10 ,  A61N5/00

CPC分类号： A61M37/0069 ,  A61N5/1007 ,  A61N5/1027 ,  A61N2005/1011

摘要： The present invention provides devices for depositing objects into tissue of an animal. The devices include a cannula having a proximal end and an opposite distal end insertable into tissue and defining an exit aperture. The cannula has a sidewall between the distal and proximal ends and defines a passageway in communication with the exit aperture. A distal retaining tab extends from an inner surface of the cannula and is positioned across at least a portion of the passageway adjacent the exit aperture. The distal tab has a first closed position blocking the passageway and a second open position wherein the tab is urged towards the sidewall to allow an object to pass. The tab is resilient to return to the first position after the object passes the tab. In some embodiments, the invention also includes a proximal retaining tab adjacent the proximal end of the cannula and positionable to block a portion of the passageway. The invention also a stylet that is slidable within the passageway to urge the objects out through the exit aperture.

摘要翻译： 本发明提供了用于将物体沉积到动物组织中的装置。 这些装置包括具有近端和相对的远端插入到组织中并限定出口孔的插管。 套管在远端和近端之间具有侧壁，并且限定与出口孔连通的通道。 远侧保持突出部从套管的内表面延伸并且位于与出口孔相邻的通道的至少一部分上。 远端突片具有阻挡通道的第一关闭位置和第二打开位置，其中突片朝向侧壁被推动以允许物体通过。 标签弹性回到对象通过标签后的第一个位置。 在一些实施例中，本发明还包括邻近套管的近端并且可定位成阻挡通道的一部分的近侧保持突出部。 本发明还提供一种可在通道内滑动以便通过出口孔推动物体的探针。

公开(公告)号：US20050059666A1

公开(公告)日：2005-03-17

申请号：US10970216

申请日：2004-10-21

申请人： Michael Miller

发明人： Michael Miller

IPC分类号： A61K31/18 ,  A61K31/506 ,  A61P1/04 ,  A61P11/06 ,  A61P17/00 ,  A61P17/06 ,  A61P19/02 ,  A61P25/28 ,  A61P29/00 ,  A61P31/12 ,  A61P31/18 ,  A61P37/02 ,  A61P37/08 ,  A61P43/00 ,  C07D401/14 ,  C07D403/06 ,  C07D409/14 ,  C07D417/14 ,  A61K31/496 ,  A61K31/4545 ,  C07D43/14

CPC分类号： C07D401/14 ,  A61K31/18 ,  A61K31/506 ,  A61K45/06 ,  C07D403/06 ,  C07D409/14 ,  C07D417/14 ,  A61K2300/00

摘要： Compounds of the formula or a pharmaceutically acceptable salt or isomer thereof, wherein: Q, X and Z are CH or N; R, R4-R7 and R13 are H or alkyl; R1 is H, alkyl, fluoroalkyl, R9-arylalkyl, R9-heteroarylalkyl, alkyl-SO2—, cycloalkyl-SO2—, fluoroalkyl-SO2—, R9-aryl-SO2—, R9-heteroaryl-SO2-, N(R22)(R23)—SO2—, alkyl-C(O)—, cycloalkyl-C(O)—, fluoroalkyl-C(O)—, R9-aryl-C(O)—, NH-alkyl-C(O)— or R9-aryl-NH—C(O)—; R2 is H and R3 is H, alkyl, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, R9-aryl, R9-arylalkyl, R9-heteroaryl, or R9-heteroarylalkyl, and when X and Z are each CH, R3 is alkoxy, R9-aryloxy, R9-heteroaryloxy, alkylC(O)O—, alkylaminoC(O)O—, alkylC(O)NR13—, alkylOC(O)NR13— or alkylaminoC(O)NR13—; or R2 and R3 together are ═O, ═NOR10, ═N—NR11R12 or ═CH-alkyl; R8 is substituted phenyl, substituted heteroaryl, naphthyl, fluorenyl, diphenymethyl, alpha-substituted benzyl or alpha-substituted heteroarylmethyl; R9-R12 are as defined; are disclosed for the treatment of HIV, solid organ transplant rejection, graft v. host disease, inflammatory diseases, atopic dermatitis, asthma, allergies or multiple sclerosis, as well as pharmaceutical compositions and combinations with antiviral or anti-inflammatory agents.

摘要翻译： 下式的化合物或其药学上可接受的盐或异构体，其中：Q，X和Z是CH或N; R 4，R 4 -R 7和R 13是H或烷基; R 1是H，烷基，氟烷基，R 9 - 芳基烷基，R 9 - 杂芳基烷基，烷基-SO 2 - ，环烷基-SO 2 - ，氟烷基-SO 2 - ，R 9 - 芳基-SO 2 - R 9 - 杂芳基-SO 2 - ，N（R 22）（R 23）-SO 2 - ，烷基-C（O） - ，环烷基-C（O） - ，氟烷基-C（O） ，R 9 - 芳基-C（O） - ，NH-烷基-C（O） - 或R 9 - 芳基-NH-C（O） - ; R 2是H，R 3是H，烷基，烷氧基烷基，环烷基，环烷基烷基，R 9 - 芳基，R 9 - 芳基烷基，R 9 - 杂芳基或R 9 - 杂芳基烷基 当X和Z各自为CH时，R 3为烷氧基，R 9 - 芳氧基，R 9 - 杂芳氧基，烷基C（O）O-，烷基氨基C（O）O-，烷基C（O）NR 烷基OC（O）NR 13 - 或烷基氨基C（O）NR 13 - ; 或R 2和R 3一起为= O，= NOR 10，= N-NR 11或= CH-烷基; R 8是取代的苯基，取代的杂芳基，萘基，芴基，二苯甲基，α-取代的苄基或α-取代的杂芳基甲基; R 9 -R 12定义如上; 被公开用于治疗HIV，实体器官移植排斥，移植物抗宿主病，炎性疾病，特应性皮炎，哮喘，过敏或多发性硬化，以及药物组合物和与抗病毒或抗炎剂的组合。

公开(公告)号：US06259521B1

公开(公告)日：2001-07-10

申请号：US09412216

申请日：1999-10-05

申请人： Michael Miller ,  Greg Goodwin

发明人： Michael Miller ,  Greg Goodwin

IPC分类号： G01N2100

CPC分类号： G03F7/70558 ,  G03F7/70616

摘要： A method for controlling uniformity in a wafer is provided. A wafer is provided. A layer of photoresist is formed on the wafer, and the photoresist layer is patterned. A portion of the patterned photoresist layer is illuminated in at least first and second positions. Light reflected at the two positions is measured to generate first and second measurements. A recipe of a stepper is adjusted in response to the first measurement differing from the second measurement. A wafer processing system includes a stepper, a scatterometer, and a process controller. The stepper is adapted to expose a layer of photoresist in accordance with a recipe to generate an exposed layer of photoresist. The scatterometer is adapted to take first and second measurements in at least first and second positions on the exposed layer of photoresist. The process controller is adapted to compare the first and second measurements and adjust the recipe based on the first and second measurements.

摘要翻译： 提供了一种用于控制晶片中的均匀性的方法。 提供晶片。 在晶片上形成一层光致抗蚀剂，并对光致抗蚀剂层进行图案化。 图案化光致抗蚀剂层的一部分在至少第一和第二位置被照亮。 测量在两个位置处反射的光以产生第一和第二测量。 响应于与第二测量不同的第一测量来调节步进器的配方。 晶片处理系统包括步进器，散射仪和过程控制器。 步进器适于根据配方暴露一层光致抗蚀剂以产生曝光的光致抗蚀剂层。 散射仪适于在曝光的光致抗蚀剂层上的至少第一和第二位置进行第一和第二测量。 过程控制器适于比较第一和第二测量值，并且基于第一和第二测量来调整配方。

公开(公告)号：US5217181A

公开(公告)日：1993-06-08

申请号：US843831

申请日：1992-02-28

申请人： Christian U. Hammarskjold ,  Ulf G. Hammarskjold ,  Michael Miller

发明人： Christian U. Hammarskjold ,  Ulf G. Hammarskjold ,  Michael Miller

IPC分类号： B60N2/07

CPC分类号： B60N2/0715 ,  B60N2/071

摘要： A sliding support of the type which mounts to and traverses along a vertical support structure. The sliding support is comprised of a track, a sliding structure which is vertically supported and a non-lubricating bearing material. The track defines an interior channel which is co-extensive to the distance traversed by the sliding support and an aperture, opposite the support structure, and in communication with the internal channel. The sliding structure has a slide means located in the channel and overlying the aperture. A horizontal support means is secured to the slide means and extends through the aperture. A vertical support means is secured to the horizontal support means and maintains the horizontal support means in a horizontal plane. The non-lubricated bearing material is positioned in the channel between the channel and the slide means.

摘要翻译： 一种滑动支架，其安装在垂直支撑结构上并沿其横向移动。 滑动支架由轨道，垂直支撑的滑动结构和非润滑轴承材料构成。 该轨道限定内部通道，该内部通道与由滑动支撑件穿过的距离共同延伸，并且与支撑结构相对并且与内部通道连通。 滑动结构具有位于通道中并覆盖孔的滑动装置。 水平支撑装置固定到滑动装置并延伸穿过孔。 垂直支撑装置被固定到水平支撑装置并将水平支撑装置保持在水平面中。 非润滑的轴承材料位于通道和滑动装置之间的通道中。

公开(公告)号：US11950524B2

公开(公告)日：2024-04-09

申请号：US16939877

申请日：2020-07-27

申请人： Michael Miller

发明人： Michael Miller

IPC分类号： A01B1/20 ,  A01D7/00 ,  B25G3/02 ,  E01C19/44 ,  E04F21/24

CPC分类号： A01B1/20 ,  A01D7/00 ,  B25G3/02 ,  E01C19/44 ,  E04F21/241

摘要： A hand tool includes a tool handle and a tool head having a body portion, with the handle secured to a back support plate portion which connects normal relative to the back plate portion, a first plate portion extending from a first side of the back plate portion having a toothed edge and a second plate portion extending from a second side of the back plate portion having a level edge, wherein each of the plate portions extend at an angle of from between 5 to 45 degrees relative to the back support plate portion.